Polypharmacology
"Polypharmacology" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The design or use of pharmaceutical agents that act on multiple targets or disease pathways.
| Descriptor ID |
D064798
|
| MeSH Number(s) |
E05.295.500.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Polypharmacology".
Below are MeSH descriptors whose meaning is more specific than "Polypharmacology".
This graph shows the total number of publications written about "Polypharmacology" by people in this website by year, and whether "Polypharmacology" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Polypharmacology" by people in Profiles.
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Liao Y, Remsing Rix LL, Li X, Fang B, Izumi V, Welsh EA, Monastyrskyi A, Haura EB, Koomen JM, Doebele RC, Rix U. Differential network analysis of ROS1 inhibitors reveals lorlatinib polypharmacology through co-targeting PYK2. Cell Chem Biol. 2024 Feb 15; 31(2):284-297.e10.
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Chow YL, Singh S, Carpenter AE, Way GP. Predicting drug polypharmacology from cell morphology readouts using variational autoencoder latent space arithmetic. PLoS Comput Biol. 2022 02; 18(2):e1009888.