 Mismatch Repair Endonuclease PMS2
"Mismatch Repair Endonuclease PMS2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A MutL protein and component of the DNA MISMATCH REPAIR system. Its ENDONUCLEASE activity introduces SINGLE-STRAND DNA BREAKS which create entry points for EXO1 exonuclease to remove the strand containing the mismatch. It may also function in DNA DAMAGE signaling.
| Descriptor ID |
D000070976
|
| MeSH Number(s) |
D08.811.074.766.250 D08.811.277.040.025.215.250 D08.811.277.352.335.350.600 D12.776.260.540.250
|
| Concept/Terms |
Mismatch Repair Endonuclease PMS2- Mismatch Repair Endonuclease PMS2
- PMS1 Homolog 2, Mismatch Repair Protein
- PMS2 Protein
- Postmeiotic Segregation Increased-S. cerevisiae-2
- Postmeiotic Segregation Increased S. cerevisiae 2
- PMS-2 Protein
- PMS 2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Mismatch Repair Endonuclease PMS2".
Below are MeSH descriptors whose meaning is more specific than "Mismatch Repair Endonuclease PMS2".
This graph shows the total number of publications written about "Mismatch Repair Endonuclease PMS2" by people in this website by year, and whether "Mismatch Repair Endonuclease PMS2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Mismatch Repair Endonuclease PMS2" by people in Profiles.
-
Kahn RM, Gordhandas S, Maddy BP, Baltich Nelson B, Askin G, Christos PJ, Caputo TA, Chapman-Davis E, Holcomb K, Frey MK. Universal endometrial cancer tumor typing: How much has immunohistochemistry, microsatellite instability, and MLH1 methylation improved the diagnosis of Lynch syndrome across the population? Cancer. 2019 09 15; 125(18):3172-3183.
-
Biller JA, Butros SR, Chan-Smutko G, Abrams AN, Chung DC, Hagen CE. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 6-2016. A 10-Year-Old Boy with Abdominal Cramping and Fevers. N Engl J Med. 2016 Feb 25; 374(8):772-81.
-
Ait Ouakrim D, Dashti SG, Chau R, Buchanan DD, Clendenning M, Rosty C, Winship IM, Young JP, Giles GG, Leggett B, Macrae FA, Ahnen DJ, Casey G, Gallinger S, Haile RW, Le Marchand L, Thibodeau SN, Lindor NM, Newcomb PA, Potter JD, Baron JA, Hopper JL, Jenkins MA, Win AK. Aspirin, Ibuprofen, and the Risk of Colorectal Cancer in Lynch Syndrome. J Natl Cancer Inst. 2015 Sep; 107(9).
-
Clay MR, Allison KH, Folkins AK, Longacre TA. Risk of secondary malignancy (including breast) in patients with mismatch-repair protein deficiency. Am J Surg Pathol. 2014 Nov; 38(11):1494-500.
-
Lindsay H, Jubran RF, Wang L, Kipp BR, May WA. Simultaneous colonic adenocarcinoma and medulloblastoma in a 12-year-old with biallelic deletions in PMS2. J Pediatr. 2013 Aug; 163(2):601-3.
-
Win AK, Lindor NM, Winship I, Tucker KM, Buchanan DD, Young JP, Rosty C, Leggett B, Giles GG, Goldblatt J, Macrae FA, Parry S, Kalady MF, Baron JA, Ahnen DJ, Marchand LL, Gallinger S, Haile RW, Newcomb PA, Hopper JL, Jenkins MA. Risks of colorectal and other cancers after endometrial cancer for women with Lynch syndrome. J Natl Cancer Inst. 2013 Feb 20; 105(4):274-9.
-
Win AK, Parry S, Parry B, Kalady MF, Macrae FA, Ahnen DJ, Young GP, Lipton L, Winship I, Boussioutas A, Young JP, Buchanan DD, Arnold J, Le Marchand L, Newcomb PA, Haile RW, Lindor NM, Gallinger S, Hopper JL, Jenkins MA. Risk of metachronous colon cancer following surgery for rectal cancer in mismatch repair gene mutation carriers. Ann Surg Oncol. 2013 Jun; 20(6):1829-36.
-
Win AK, Young JP, Lindor NM, Tucker KM, Ahnen DJ, Young GP, Buchanan DD, Clendenning M, Giles GG, Winship I, Macrae FA, Goldblatt J, Southey MC, Arnold J, Thibodeau SN, Gunawardena SR, Bapat B, Baron JA, Casey G, Gallinger S, Le Marchand L, Newcomb PA, Haile RW, Hopper JL, Jenkins MA. Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study. J Clin Oncol. 2012 Mar 20; 30(9):958-64.
-
Win AK, Dowty JG, English DR, Campbell PT, Young JP, Winship I, Macrae FA, Lipton L, Parry S, Young GP, Buchanan DD, Mart?nez ME, Jacobs ET, Ahnen DJ, Haile RW, Casey G, Baron JA, Lindor NM, Thibodeau SN, Newcomb PA, Potter JD, Le Marchand L, Gallinger S, Hopper JL, Jenkins MA. Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes. Br J Cancer. 2011 Jun 28; 105(1):162-9.
-
Mauris J, Evans TC. A human PMS2 homologue from Aquifex aeolicus stimulates an ATP-dependent DNA helicase. J Biol Chem. 2010 Apr 09; 285(15):11087-92.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|