 Tiotropium Bromide
"Tiotropium Bromide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A scopolamine derivative and CHOLINERGIC ANTAGONIST that functions as a BRONCHODILATOR AGENT. It is used in the treatment of CHRONIC OBSTRUCTIVE PULMONARY DISEASE.
| Descriptor ID |
D000069447
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| MeSH Number(s) |
D02.145.074.722.822.887 D03.132.889.601.887 D03.605.084.500.722.822.887 D03.605.869.822.887
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| Concept/Terms |
Tiotropium Bromide- Tiotropium Bromide
- Bromide, Tiotropium
- 7-((hydroxybis(2-thienyl)acetyl)oxy)-9,9-dimethyl-3-oxa-9-azoniatricyclo(3.3.1.0(2,4))nonane bromide
BA 679 BR- BA 679 BR
- 679 BR, BA
- BR, BA 679
- BA-679 BR
- BA679 BR
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Below are MeSH descriptors whose meaning is more general than "Tiotropium Bromide".
Below are MeSH descriptors whose meaning is more specific than "Tiotropium Bromide".
This graph shows the total number of publications written about "Tiotropium Bromide" by people in this website by year, and whether "Tiotropium Bromide" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2015 | 1 | 1 | 2 | | 2016 | 2 | 0 | 2 | | 2017 | 3 | 0 | 3 | | 2018 | 3 | 0 | 3 | | 2019 | 4 | 0 | 4 |
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Below are the most recent publications written about "Tiotropium Bromide" by people in Profiles.
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Graham LM, Kerstjens HAM, Vogelberg C, Hamelmann E, Szefler SJ, Pisternick-Ruf W, Engel M, El Azzi G, Unseld A, Foggs MB. Safety of tiotropium Respimat? in black or African-American patients with symptomatic asthma. Respir Med. 2019 08; 155:58-60.
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Vogelberg C, Szefler SJ, Vrijlandt EJLE, Boner AL, Engel M, El Azzi G, Vulcu SD, Moroni-Zentgraf PM, Eickmeier O, Hamelmann EH. Tiotropium add-on therapy is safe and?reduces seasonal worsening in paediatric?asthma patients. Eur Respir J. 2019 06; 53(6).
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Lazarus SC, Krishnan JA, King TS, Lang JE, Blake KV, Covar R, Lugogo N, Wenzel S, Chinchilli VM, Mauger DT, Dyer AM, Boushey HA, Fahy JV, Woodruff PG, Bacharier LB, Cabana MD, Cardet JC, Castro M, Chmiel J, Denlinger L, DiMango E, Fitzpatrick AM, Gentile D, Hastie A, Holguin F, Israel E, Jackson D, Kraft M, LaForce C, Lemanske RF, Martinez FD, Moore W, Morgan WJ, Moy JN, Myers R, Peters SP, Phipatanakul W, Pongracic JA, Que L, Ross K, Smith L, Szefler SJ, Wechsler ME, Sorkness CA. Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level. N Engl J Med. 2019 05 23; 380(21):2009-2019.
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Szefler SJ, Vogelberg C, Bernstein JA, Goldstein S, Mansfield L, Zaremba-Pechmann L, Engel M, Hamelmann E. Tiotropium Is Efficacious in 6- to 17-Year-Olds with Asthma, Independent of T2 Phenotype. J Allergy Clin Immunol Pract. 2019 Sep - Oct; 7(7):2286-2295.e4.
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Grossman NL, Doros GD, Fandino N, Fuhlbrigge AL, Pace WD, Wechsler ME, Yawn BP, Israel E. Susceptibility to exacerbations in Black adults with asthma. J Asthma. 2019 Jul; 56(7):704-710.
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Hamelmann E, Szefler SJ. Efficacy and Safety of Tiotropium in Children and Adolescents. Drugs. 2018 Mar; 78(3):327-338.
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Vrijlandt EJLE, El Azzi G, Vandewalker M, Rupp N, Harper T, Graham L, Szefler SJ, Moroni-Zentgraf P, Sharma A, Vulcu SD, Sigmund R, Chawes B, Engel M, Bisgaard H. Safety and efficacy of tiotropium in children aged 1-5 years with persistent asthmatic symptoms: a randomised, double-blind, placebo-controlled trial. Lancet Respir Med. 2018 02; 6(2):127-137.
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Hamelmann E, Vogelberg C, Szefler SJ. Reply to 'Can a better patient phenotyping predict the efficacy of tiotropium in asthmatic adolescents?' Expert Opin Pharmacother. 2017 06; 18(8):837-838.
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Szefler SJ, Murphy K, Harper T, Boner A, Laki I, Engel M, El Azzi G, Moroni-Zentgraf P, Finnigan H, Hamelmann E. A phase III randomized controlled trial of tiotropium add-on therapy in children with severe symptomatic asthma. J Allergy Clin Immunol. 2017 Nov; 140(5):1277-1287.
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Hamelmann E, Vogelberg C, Szefler SJ. Tiotropium for the treatment of asthma in adolescents. Expert Opin Pharmacother. 2017 Feb; 18(3):305-312.
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