 Thyroid Hormone Receptors beta
"Thyroid Hormone Receptors beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by alternative splicing. Mutations in the THRB gene cause THYROID HORMONE RESISTANCE SYNDROME.
| Descriptor ID |
D037042
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| MeSH Number(s) |
D12.776.624.664.700.830.750 D12.776.826.850.750
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| Concept/Terms |
Thyroid Hormone Receptors beta- Thyroid Hormone Receptors beta
- TR beta
- Thyroid Hormone Receptor beta
- ERBA2 Gene Products
- Gene Products, ERBA2
- NR1A2 Gene Products
- Gene Products, NR1A2
- Receptors beta, Thyroid Hormone
- c-erbA beta
- c erbA beta
- THRB Gene Products
- Gene Products, THRB
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Below are MeSH descriptors whose meaning is more general than "Thyroid Hormone Receptors beta".
Below are MeSH descriptors whose meaning is more specific than "Thyroid Hormone Receptors beta".
This graph shows the total number of publications written about "Thyroid Hormone Receptors beta" by people in this website by year, and whether "Thyroid Hormone Receptors beta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thyroid Hormone Receptors beta" by people in Profiles.
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Bolf EL, Gillis NE, Davidson CD, Cozzens LM, Kogut S, Tomczak JA, Frietze S, Carr FE. Common tumor-suppressive signaling of thyroid hormone receptor beta in breast and thyroid cancer cells. Mol Carcinog. 2021 12; 60(12):874-885.
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Bolf EL, Gillis NE, Davidson CD, Rodriguez PD, Cozzens L, Tomczak JA, Frietze S, Carr FE. Thyroid Hormone Receptor Beta Induces a Tumor-Suppressive Program in Anaplastic Thyroid Cancer. Mol Cancer Res. 2020 10; 18(10):1443-1452.
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Gillis NE, Taber TH, Bolf EL, Beaudet CM, Tomczak JA, White JH, Stein JL, Stein GS, Lian JB, Frietze S, Carr FE. Thyroid Hormone Receptor ? Suppression of RUNX2 Is Mediated by Brahma-Related Gene 1-Dependent Chromatin Remodeling. Endocrinology. 2018 06 01; 159(6):2484-2494.
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O'Shea PJ, Kim DW, Logan JG, Davis S, Walker RL, Meltzer PS, Cheng SY, Williams GR. Advanced bone formation in mice with a dominant-negative mutation in the thyroid hormone receptor ? gene due to activation of Wnt/?-catenin protein signaling. J Biol Chem. 2012 May 18; 287(21):17812-17822.
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