 Buprenorphine
"Buprenorphine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
| Descriptor ID |
D002047
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| MeSH Number(s) |
D03.132.577.249.150 D03.605.497.150 D03.633.400.686.150 D04.615.723.795.150
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| Concept/Terms |
Subutex- Subutex
- Buprex
- Temgesic
- Temgésic
6029-M- 6029-M
- 6029 M
- 6029M
- RX-6029-M
- RX 6029 M
- RX6029M
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Below are MeSH descriptors whose meaning is more general than "Buprenorphine".
Below are MeSH descriptors whose meaning is more specific than "Buprenorphine".
This graph shows the total number of publications written about "Buprenorphine" by people in this website by year, and whether "Buprenorphine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 2 | 1 | 3 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 1 | 3 | | 2018 | 2 | 2 | 4 | | 2019 | 7 | 5 | 12 | | 2020 | 16 | 1 | 17 | | 2021 | 15 | 0 | 15 | | 2022 | 16 | 0 | 16 | | 2023 | 22 | 0 | 22 | | 2024 | 13 | 2 | 15 | | 2025 | 5 | 0 | 5 |
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Below are the most recent publications written about "Buprenorphine" by people in Profiles.
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Becker WC, Seal KH, Nelson DB, DeRonne BM, Kats AM, Morasco BJ, Frank JW, Makris UE, Painter JT, Allen KD, Mixon AS, Bohnert A, Reznik TE, Hagedorn HJ, Hammett P, Borsari B, Baxley C, Krebs EE. Buprenorphine, Pain, and Opioid Use in Patients Taking High-Dose Long-Term Opioids: A Randomized Clinical Trial. JAMA Intern Med. 2025 Apr 01; 185(4):372-381.
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Lebin JA, Sommers S, Lun Z, Hensen C, Hoppe JA. Clinical decision support as an implementation strategy to expand identification and administration of treatment of opioid use disorder in the emergency department. J Subst Use Addict Treat. 2025 May; 172:209653.
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Iscoe MS, Diniz Hooper C, Levy DR, Buchanan L, Dziura J, Meeker D, Taylor RA, D'Onofrio G, Oladele C, Sarpong DF, Paek H, Wilson FP, Heagerty PJ, Delgado MK, Hoppe J, Melnick ER. Adaptive decision support for addiction treatment to implement initiation of buprenorphine for opioid use disorder in the emergency department: protocol for the ADAPT Multiphase Optimization Strategy trial. BMJ Open. 2025 Feb 20; 15(2):e098072.
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Fine DR, Critchley N, Hart K, Regan S, Sporn N, Gaeta J, Wright J, Kruse G, Baggett TP. Buprenorphine adherence among a prospective cohort of homeless-experienced adults with opioid use disorder. Drug Alcohol Depend. 2025 May 01; 270:112598.
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Hall TL, Mendez D, Sobczak C, Mathieu S, Wiggins K, Cebuhar K, Quintana L, Weiss J, Knierim K. Evaluation of a Program Designed to Support Implementation of Prescribing Medication for Treatment of Opioid Use Disorder in Primary Care Practices. Ann Fam Med. 2025 Jan 27; 23(1):44-51.
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Tremonti C, Blogg J, Jamshidi N, Harjanto R, Miles N, Ismay C, Page R, Mills L, Buckley N, Perananthan V, Lintzeris N, Haber P. Methadone-Buprenorphine Transfers Using Low Dosing of Buprenorphine: An Open-label, Nonrandomized Clinical Trial. J Addict Med. 2025 Jan-Feb 01; 19(1):75-82.
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Krumheuer A, Janke AT, Nickel A, Kim E, Bailes C, Ager EE, Purington EK, Mahmood SM, Hooyer M, Ryan ML, Baker JE, Purdy M, Greineder CF, Commissaris CV, Smith SN, Fung CM, Losman ED. Implementation of an Emergency Department Opioid Use Disorder Initiative: Clinical Processes and Institution Specific Education Improve Care. J Emerg Med. 2025 Apr; 71:104-113.
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Sugarman OK, Harris SJ, Byrne L, Flanagan V, Gattine S, Desai I, Heidari O, Gibbons JB, Whaley S, Lucas D, Pugh T, McBride A, Saloner B. How emergency departments are responding to the opioid crisis: Results from a statewide survey in Kentucky. Addict Sci Clin Pract. 2024 Nov 08; 19(1):78.
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Castry M, Tin Y, Feder NM, Lewis N, Chatterjee A, Rudorf M, Samet JH, Beers D, Medley B, Gilbert L, Linas BP, Barocas JA. An economic analysis of the cost of mobile units for harm reduction, naloxone distribution, and medications for opioid use disorder. J Subst Use Addict Treat. 2024 Dec; 167:209517.
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Thakrar AP, Christine PJ, Siaw-Asamoah A, Spadaro A, Faude S, Snider CK, Delgado MK, Lowenstein M, Kampman K, Perrone J, Nelson LS, Kilaru AS. Buprenorphine-Precipitated Withdrawal Among Hospitalized Patients Using Fentanyl. JAMA Netw Open. 2024 09 03; 7(9):e2435895.
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