 Methadone
"Methadone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
| Descriptor ID |
D008691
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| MeSH Number(s) |
D02.522.675
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Methadone".
Below are MeSH descriptors whose meaning is more specific than "Methadone".
This graph shows the total number of publications written about "Methadone" by people in this website by year, and whether "Methadone" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 1 | 2 | | 2002 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2008 | 1 | 3 | 4 | | 2010 | 1 | 1 | 2 | | 2011 | 3 | 0 | 3 | | 2013 | 3 | 2 | 5 | | 2014 | 0 | 1 | 1 | | 2015 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 0 | 2 | 2 | | 2019 | 5 | 3 | 8 | | 2020 | 4 | 4 | 8 | | 2021 | 0 | 4 | 4 | | 2022 | 0 | 4 | 4 | | 2023 | 2 | 6 | 8 | | 2024 | 5 | 2 | 7 | | 2025 | 8 | 1 | 9 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Methadone" by people in Profiles.
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Scherbak Y, Wehrer M, Jacknin G, Nelson A, Calcaterra S. Bridging the Gap: Empowering Pharmacists in Inpatient Injectable Naltrexone and Hospital-Dispensed Methadone Process Development. J Am Coll Clin Pharm. 2026 Mar; 9(3):e70186.
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Kulik GL, Hsu HY, Rudolph J, Jiang Y, Erlandson KM, Piggott DA, Mehta S, Walston JD, Kirk G, Brown TT, Sun J. The association of methadone use with physical function and frailty among persons who inject drugs. Addiction. 2026 May; 121(5):1217-1226.
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Henthorn TK, Kharasch ED. Population Pharmacokinetics of Intravenous Methadone Enantiomers in Adults: A Comprehensive Model. Clin Pharmacol Ther. 2026 Mar; 119(3):739-750.
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Nunes JC, Costa GPA, De Aquino JP, Adinoff B. Expanding Access to Buprenorphine and Methadone: Global Perspectives and Policy Recommendations. Subst Use Addctn J. 2026 Apr; 47(2):595-610.
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Calcaterra SL, Weimer MB, Grimm E, Scherbak Y, Abdel Galil R, Berger O, Bowman LA, Nesbit SA, Barany A, Buresh ME. Leveraging the 72-Hour Rule Change to Support Transition From Hospital to Opioid Treatment Program. JAMA Netw Open. 2025 Nov 03; 8(11):e2544996.
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Guan X, Jurecka C, Padmanabhan P, Yamkovoy K, Christine PJ, Binswanger IA, Glanz JM, Kline DM, Barocas JA. Impact of increased criminal penalties for fentanyl possession on initiation and retention on medications for opioid use disorder in Colorado. Int J Drug Policy. 2025 Dec; 146:105037.
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Calcaterra SL, Lockhart S, Natvig C, Mikulich-Gilbertson SK. Measuring the Impact of a Multi-Site In-Hospital Intervention for Opioid Use Disorder Treatment Provision: A Survey of Hospital-Based Clinicians. J Gen Intern Med. 2026 03; 41(4):1048-1057.
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Christine PJ, Blum J, Tillman AR, Braun HM, Hinrichs M, Hurley H, Al-Tayyib A. Evaluation of a Novel Patient-Centered Methadone Restart Protocol. JAMA Netw Open. 2025 Aug 01; 8(8):e2529393.
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Nunes JC, Adinoff B. Reducing stigma and expanding methadone access in the U.S.: the Modernizing Opioid Treatment Access Act and beyond. Am J Drug Alcohol Abuse. 2025; 51(4):413-418.
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Haber LA, Berk J, Taub J, South AM. Initiating Medications for Opioid Use Disorder in Hospitalized Incarcerated Patients. J Gen Intern Med. 2025 11; 40(14):3481-3485.
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