 Lipase
"Lipase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. It is produced by glands on the tongue and by the pancreas and initiates the digestion of dietary fats. (From Dorland, 27th ed) EC 3.1.1.3.
| Descriptor ID |
D008049
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| MeSH Number(s) |
D08.811.277.352.100.400
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| Concept/Terms |
Lipase- Lipase
- Triacylglycerol Lipase
- Triolean Hydrolase
- Hydrolase, Triolean
- Triglyceridase
- Triglyceride Lipase
- Lipase, Triglyceride
- Triacylglycerol Hydrolase
- Hydrolase, Triacylglycerol
- Tributyrinase
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Below are MeSH descriptors whose meaning is more general than "Lipase".
Below are MeSH descriptors whose meaning is more specific than "Lipase".
This graph shows the total number of publications written about "Lipase" by people in this website by year, and whether "Lipase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1999 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 1 | 2 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 1 | 2 | | 2008 | 1 | 1 | 2 | | 2010 | 1 | 1 | 2 | | 2011 | 2 | 1 | 3 | | 2013 | 3 | 1 | 4 | | 2014 | 0 | 2 | 2 | | 2015 | 1 | 2 | 3 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2020 | 2 | 1 | 3 | | 2021 | 2 | 2 | 4 | | 2023 | 0 | 2 | 2 | | 2024 | 0 | 1 | 1 | | 2025 | 4 | 1 | 5 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lipase" by people in Profiles.
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Salmon K, Cohen CC, Lange L, Dabelea D, Perng W. Dietary Patterns, Hepatic Fat Fraction, and the Role of Genotype. Nutrients. 2026 Mar 28; 18(7).
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Kelaita DJ, Kaar JL, Schwartz DK. Mixed lipid bilayers enable enhanced stability and activity retention of Lipase A in low-pH environments. Colloids Surf B Biointerfaces. 2026 Jan; 257:115167.
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Kumar M, Wu Y, Knapp J, Pontius CL, Park D, Witte RE, McAllister R, Gupta K, Rajagopalan KN, De Camilli P, Ryan TA. Triglycerides are an important fuel reserve for synapse function in the brain. Nat Metab. 2025 Jul; 7(7):1392-1403.
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Bisirri EA, Kaar JL, Schwartz DK. High-Throughput Screening Identifies Anionic Polymer Supports that Improve Enzyme Activity at Low pH and High Temperature. Langmuir. 2025 Mar 04; 41(8):5335-5346.
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Patterson WB, Young ND, Holzhausen EA, Lurmann F, Liang D, Walker DI, Jones DP, Liao J, Chen Z, Conti DV, Chatzi L, Goodrich JA, Alderete TL. Oxidative gaseous air pollutant exposure interacts with PNPLA3-I148M genotype to influence liver fat fraction and multi-omics profiles in young adults. Environ Pollut. 2025 Mar 01; 368:125692.
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Greenblott DN, Calderon CP, Randolph TW. Representative training data sets are critical for accurate machine-learning classification of microscopy images of particles formed by lipase-catalyzed polysorbate hydrolysis. J Pharm Sci. 2025 Feb; 114(2):1254-1263.
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Sánchez-Morán H, Kaar JL, Schwartz DK. Supra-biological performance of immobilized enzymes enabled by chaperone-like specific non-covalent interactions. Nat Commun. 2024 Mar 14; 15(1):2299.
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Bisirri EA, Wright TA, Schwartz DK, Kaar JL. Tuning Polymer Composition Leads to Activity-Stability Tradeoff in Enzyme-Polymer Conjugates. Biomacromolecules. 2023 09 11; 24(9):4033-4041.
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Floan Sachs G, Ourshalimian S, Jensen AR, Kelley-Quon LI, Padilla BE, Shew SB, Lofberg KM, Smith CA, Roach JP, Pandya SR, Russell KW, Ignacio RC. Machine learning to predict pediatric choledocholithiasis: A Western Pediatric Surgery Research Consortium retrospective study. Surgery. 2023 10; 174(4):934-939.
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Schmidt KA, Jones RB, Rios C, Corona Y, Berger PK, Plows JF, Alderete TL, Fogel J, Hampson H, Hartiala JA, Cai Z, Allayee H, Nayak KS, Sinatra FR, Harlan G, Pickering TA, Salvy SJ, Mack WJ, Kohli R, Goran MI. Clinical Intervention to Reduce Dietary Sugar Does Not Affect Liver Fat in Latino Youth, Regardless of PNPLA3 Genotype: A Randomized Controlled Trial. J Nutr. 2022 07 06; 152(7):1655-1665.
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