Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate.
Cook DR, Maxwell IH, Glode LM, Maxwell F, Stevens JO, Purner MB, Wagner E, Curiel DT, Curiel TJ. Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate. Cancer Biother. 1994; 9(2):131-41.
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Adenoviridae
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Animals
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Biotin
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Cell Line, Transformed
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Diphtheria Toxin
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DNA, Recombinant
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Female
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Gene Expression Regulation, Neoplastic
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Genes, Immunoglobulin
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Genes, Reporter
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Genes, Synthetic
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Genetic Therapy
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Herpesvirus 4, Human
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Immunoglobulin kappa-Chains
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Ligands
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Lymphoma, B-Cell
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Male
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Mice
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Mice, SCID
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Peptide Fragments
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Polylysine
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Promoter Regions, Genetic
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Recombinant Fusion Proteins