 Thyrotropin, beta Subunit
"Thyrotropin, beta Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The beta subunit of thyroid stimulating hormone, thyrotropin. It is a 112-amino acid glycopolypeptide of about 16 kD. Full biological activity of TSH requires the non-covalently bound heterodimers of an alpha and a beta subunit.
| Descriptor ID |
D037322
|
| MeSH Number(s) |
D06.472.699.631.525.883.500 D12.644.548.691.525.883.500
|
| Concept/Terms |
Thyrotropin, beta Subunit- Thyrotropin, beta Subunit
- Thyrotropin, beta Chain
- Thyroid Stimulating Hormone, beta Subunit
- TSHB Gene Product
- Thyrotropin-beta
- Thyrotropin beta
- TSH, beta Subunit
- TSH-beta
- TSH beta
- TSH, beta Chain
- Thyrotropin, beta Polypeptide Chain
|
Below are MeSH descriptors whose meaning is more general than "Thyrotropin, beta Subunit".
Below are MeSH descriptors whose meaning is more specific than "Thyrotropin, beta Subunit".
This graph shows the total number of publications written about "Thyrotropin, beta Subunit" by people in this website by year, and whether "Thyrotropin, beta Subunit" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Thyrotropin, beta Subunit" by people in Profiles.
-
Janssen JS, Sharma V, Pugazhenthi U, Sladek C, Wood WM, Haugen BR. A rexinoid antagonist increases the hypothalamic-pituitary-thyroid set point in mice and thyrotrope cells. Mol Cell Endocrinol. 2011 Jun 06; 339(1-2):1-6.
-
Zhang Z, Florez S, Gutierrez-Hartmann A, Martin JF, Amendt BA. MicroRNAs regulate pituitary development, and microRNA 26b specifically targets lymphoid enhancer factor 1 (Lef-1), which modulates pituitary transcription factor 1 (Pit-1) expression. J Biol Chem. 2010 Nov 05; 285(45):34718-28.
-
Jonsen MD, Duval DL, Gutierrez-Hartmann A. The 26-amino acid beta-motif of the Pit-1beta transcription factor is a dominant and independent repressor domain. Mol Endocrinol. 2009 Sep; 23(9):1371-84.
-
Sarapura VD, Wood WM, Woodmansee WW, Haakinson DJ, Dowding JM, Gordon DF, Ridgway EC. Pituitary tumors arising from glycoprotein hormone alpha-subunit-deficient mice contain transcription factors and receptors present in thyrotropes. Pituitary. 2006; 9(1):11-8.
-
McDermott MT, Haugen BR, Black JN, Wood WM, Gordon DF, Ridgway EC. Congenital isolated central hypothyroidism caused by a "hot spot" mutation in the thyrotropin-beta gene. Thyroid. 2002 Dec; 12(12):1141-6.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|