Dihydroergotoxine
"Dihydroergotoxine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixture of three different hydrogenated derivatives of ERGOTAMINE: DIHYDROERGOCORNINE; DIHYDROERGOCRISTINE; and DIHYDROERGOCRYPTINE. Dihydroergotoxine has been proposed to be a neuroprotective agent and a nootropic agent. The mechanism of its therapeutic actions is not clear, but it can act as an alpha-adrenergic antagonist and a dopamine agonist. The methanesulfonate salts of this mixture of alkaloids are called ERGOLOID MESYLATES.
| Descriptor ID |
D004088
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| MeSH Number(s) |
D03.132.327.412.250 D03.633.400.562.400
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Dihydroergotoxine".
Below are MeSH descriptors whose meaning is more specific than "Dihydroergotoxine".
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Below are the most recent publications written about "Dihydroergotoxine" by people in Profiles.
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Thompson TL, Filley CM, Mitchell WD, Culig KM, LoVerde M, Byyny RL. Lack of efficacy of hydergine in patients with Alzheimer's disease. N Engl J Med. 1990 Aug 16; 323(7):445-8.
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Nussenblatt RB, Austin HA, Palestine AG, Preuss HG. Hydergine and cyclosporin nephrotoxicity. Lancet. 1986 May 24; 1(8491):1220-1.