 Scleritis
"Scleritis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Refers to any inflammation of the sclera including episcleritis, a benign condition affecting only the episclera, which is generally short-lived and easily treated. Classic scleritis, on the other hand, affects deeper tissue and is characterized by higher rates of visual acuity loss and even mortality, particularly in necrotizing form. Its characteristic symptom is severe and general head pain. Scleritis has also been associated with systemic collagen disease. Etiology is unknown but is thought to involve a local immune response. Treatment is difficult and includes administration of anti-inflammatory and immunosuppressive agents such as corticosteroids. Inflammation of the sclera may also be secondary to inflammation of adjacent tissues, such as the conjunctiva.
| Descriptor ID |
D015423
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| MeSH Number(s) |
C11.790.500
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| Concept/Terms |
Necrotizing Scleritis- Necrotizing Scleritis
- Necrotizing Scleritides
- Scleritides, Necrotizing
- Scleritis, Necrotizing
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Below are MeSH descriptors whose meaning is more general than "Scleritis".
Below are MeSH descriptors whose meaning is more specific than "Scleritis".
This graph shows the total number of publications written about "Scleritis" by people in this website by year, and whether "Scleritis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2022 | 3 | 0 | 3 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Scleritis" by people in Profiles.
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Junek ML, Zhao L, Garner S, Cuthbertson D, Pagnoux C, Koening CL, Langford CA, McAlear CA, Monach PA, Moreland LW, Rhee RL, Seo P, Specks U, Sreih AG, Warrington K, Wechsler ME, Merkel PA, Khalidi NA. Ocular manifestations of ANCA-associated vasculitis. Rheumatology (Oxford). 2023 07 05; 62(7):2517-2524.
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Reddy AK, Kolfenbach JR, Palestine AG. Ocular manifestations of rheumatoid arthritis. Curr Opin Ophthalmol. 2022 Nov 01; 33(6):551-556.
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Mehta N, Taravella MJ, Reddy AK. Necrotizing Scleritis Secondary to Exposed Polypropylene Suture. Ophthalmology. 2023 Jul; 130(7):691.
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Mudie LI, Reddy AK, Patnaik JL, Pecen P, Kim E, Cole K, Palestine AG. Evaluation of the SUN Classification Criteria for Uveitides in an Academic Uveitis Practice. Am J Ophthalmol. 2022 09; 241:57-63.
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Shah J, Shah A, Hassman L, Gutierrez A. Ocular Manifestations of Inflammatory Bowel Disease. Inflamm Bowel Dis. 2021 10 20; 27(11):1832-1838.
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Wargo JJ, Adams M, Trevino J. Subcorneal pustular dermatosis and episcleritis associated with poorly controlled ulcerative colitis. BMJ Case Rep. 2017 Jan 30; 2017.
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Levitt AE, McManus KT, McClellan AL, Davis JL, Goldhardt R, Galor A. Ocular Inflammation in the Setting of Concomitant Systemic Autoimmune Conditions in an Older Male Population. Cornea. 2015 Jul; 34(7):762-7.
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Raiji VR, Palestine AG, Parver DL. Scleritis and systemic disease association in a community-based referral practice. Am J Ophthalmol. 2009 Dec; 148(6):946-50.
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Davidson RS, Erlanger M, Taravella M, Gregory DG, Durairaj VD. Tarsoconjunctival pedicle flap for the management of a severe scleral melt. Cornea. 2007 Feb; 26(2):235-7.
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Taravella MJ, Johnson DW, Petty JG, Keyser RB, Foster CS, Lundberg BE. Infectious posterior scleritis caused by Pseudallescheria boydii. Clinicopathologic findings. Ophthalmology. 1997 Aug; 104(8):1312-6.
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