 Homogentisate 1,2-Dioxygenase
"Homogentisate 1,2-Dioxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mononuclear Fe(II)-dependent oxygenase, this enzyme catalyzes the conversion of homogentisate to 4-maleylacetoacetate, the third step in the pathway for the catabolism of TYROSINE. Deficiency in the enzyme causes ALKAPTONURIA, an autosomal recessive disorder, characterized by homogentisic aciduria, OCHRONOSIS and ARTHRITIS. This enzyme was formerly characterized as EC 1.13.1.5 and EC 1.99.2.5.
| Descriptor ID |
D050560
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| MeSH Number(s) |
D08.811.682.690.416.326
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| Concept/Terms |
Homogentisate 1,2-Dioxygenase- Homogentisate 1,2-Dioxygenase
- 1,2-Dioxygenase, Homogentisate
- Homogentisate 1,2 Dioxygenase
- Homogentisic Acid Oxidase
- Acid Oxidase, Homogentisic
- Oxidase, Homogentisic Acid
- Homogentisate Oxygenase
- Oxygenase, Homogentisate
- Homogentisate Dioxygenase
- Dioxygenase, Homogentisate
- Homogentisate Oxidase
- Oxidase, Homogentisate
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Below are MeSH descriptors whose meaning is more general than "Homogentisate 1,2-Dioxygenase".
Below are MeSH descriptors whose meaning is more specific than "Homogentisate 1,2-Dioxygenase".
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