 Insulin-Like Growth Factor II
"Insulin-Like Growth Factor II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults.
| Descriptor ID |
D007335
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| MeSH Number(s) |
D12.644.276.937.420 D12.776.124.862.425 D12.776.467.937.420 D23.529.937.420
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| Concept/Terms |
Insulin-Like Growth Factor II- Insulin-Like Growth Factor II
- IGF-II
- Insulin Like Growth Factor II
- Insulin-Like Somatomedin Peptide II
- Insulin Like Somatomedin Peptide II
- Multiplication-Stimulating Factor
- Factor, Multiplication-Stimulating
- Multiplication Stimulating Factor
- Somatomedin A
- Somatomedin MSA
- IGF-2
- Multiplication-Stimulating Activity
- Multiplication Stimulating Activity
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Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor II".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor II".
This graph shows the total number of publications written about "Insulin-Like Growth Factor II" by people in this website by year, and whether "Insulin-Like Growth Factor II" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2006 | 2 | 1 | 3 | | 2007 | 0 | 1 | 1 | | 2008 | 2 | 0 | 2 | | 2009 | 1 | 1 | 2 | | 2010 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2017 | 3 | 0 | 3 | | 2018 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor II" by people in Profiles.
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McCoard S, Haack N, Heiser A, Maclean P. Effect of birth rank, and placentome subtype on expression of genes involved in placental nutrient transport in sheep. Theriogenology. 2023 Jun; 203:109-117.
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Ali A, Swanepoel CM, Winger QA, Rozance PJ, Anthony RV. Chorionic somatomammotropin RNA interference alters fetal liver glucose utilization. J Endocrinol. 2020 12; 247(3):251-262.
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White A, Louey S, Chang EI, Boehmer BH, Goldstrohm D, Jonker SS, Rozance PJ. A 1?week IGF-1 infusion decreases arterial insulin concentrations but increases pancreatic insulin content and islet vascularity in fetal sheep. Physiol Rep. 2018 09; 6(17):e13840.
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Perng W, Rifas-Shiman SL, McCulloch S, Chatzi L, Mantzoros C, Hivert MF, Oken E. Associations of cord blood metabolites with perinatal characteristics, newborn anthropometry, and cord blood hormones in project viva. Metabolism. 2017 11; 76:11-22.
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Miles FL, Goodman PJ, Tangen C, Torkko KC, Schenk JM, Song X, Pollak M, Thompson IM, Neuhouser ML. Interactions of the Insulin-Like Growth Factor Axis and Vitamin D in Prostate Cancer Risk in the Prostate Cancer Prevention Trial. Nutrients. 2017 Apr 12; 9(4).
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Sun RC, Choi PM, Diaz-Miron JL, Sommovilla J, Guo J, Erwin CR, Warner BW. Epithelial IGF1R is dispensable for IGF2 mediated enhanced intestinal adaptation in retinoblastoma-deficient mice. J Pediatr Surg. 2017 Jun; 52(6):1026-1030.
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Higgins JS, Vaughan OR, Fernandez de Liger E, Fowden AL, Sferruzzi-Perri AN. Placental phenotype and resource allocation to fetal growth are modified by the timing and degree of hypoxia during mouse pregnancy. J Physiol. 2016 Mar 01; 594(5):1341-56.
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Choi PM, Sun RC, Sommovilla J, Diaz-Miron J, Guo J, Erwin CR, Warner BW. IGF-2 is necessary for retinoblastoma-mediated enhanced adaptation after small-bowel resection. J Gastrointest Surg. 2014 Nov; 18(11):1887-93.
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Neville MC, Webb P, Ramanathan P, Mannino MP, Pecorini C, Monks J, Anderson SM, MacLean P. The insulin receptor plays an important role in secretory differentiation in the mammary gland. Am J Physiol Endocrinol Metab. 2013 Nov 01; 305(9):E1103-14.
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Popkie AP, Zeidner LC, Albrecht AM, D'Ippolito A, Eckardt S, Newsom DE, Groden J, Doble BW, Aronow B, McLaughlin KJ, White P, Phiel CJ. Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci. J Biol Chem. 2010 Dec 31; 285(53):41337-47.
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