 Nonsuppressible Insulin-Like Activity
"Nonsuppressible Insulin-Like Activity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A blood protein (NSILA) which mimics the biological activity of insulin in serum, but is not suppressed by insulin antibodies. During acid-ethanol extraction of Cohn fraction III, 10% of the activity is found in the supernatant (NSILA-S) and the remaining activity in the precipitate (NSILA-P). The latter is a large molecular compound, much less stable than the soluble fraction. NSILA-S is a more potent growth factor than insulin and exhibits sulfation activity.
| Descriptor ID |
D009632
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| MeSH Number(s) |
D12.776.124.862.575
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| Concept/Terms |
Nonsuppressible Insulin-Like Activity- Nonsuppressible Insulin-Like Activity
- Activity, Nonsuppressible Insulin-Like
- Insulin-Like Activity, Nonsuppressible
- Nonsuppressible Insulin Like Activity
- Nonsuppressible Insulinlike Activity
- Activity, Nonsuppressible Insulinlike
- Insulinlike Activity, Nonsuppressible
- NSILA
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Below are MeSH descriptors whose meaning is more general than "Nonsuppressible Insulin-Like Activity".
Below are MeSH descriptors whose meaning is more specific than "Nonsuppressible Insulin-Like Activity".
This graph shows the total number of publications written about "Nonsuppressible Insulin-Like Activity" by people in this website by year, and whether "Nonsuppressible Insulin-Like Activity" was a major or minor topic of these publications.
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Below are the most recent publications written about "Nonsuppressible Insulin-Like Activity" by people in Profiles.
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Schalch DS, Heinrich UE, Draznin B, Johnson CJ, Miller LL. Role of the liver in regulating somatomedin activity: hormonal effects on the synthesis and release of insulin-like growth factor and its carrier protein by the isolated perfused rat liver. Endocrinology. 1979 Apr; 104(4):1143-51.
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Burstein PJ, Draznin B, Johnson CJ, Schalch DS. The effect of hypothyroidism on growth, serum growth hormone, the growth hormone-dependent somatomedin, insulin-like growth factor, and its carrier protein in rats. Endocrinology. 1979 Apr; 104(4):1107-11.
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