Rats, Inbred OLETF

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"Rats, Inbred OLETF" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An inbred strain of Long-Evans rats that develops hyperglycemia, hyperinsulinemia, and mild obesity, mostly in males, that resembles non-insulin-dependent diabetes mellitus in humans. It was developed from outbred Long-Evans stock in 1983.

Descriptor ID	D020334
MeSH Number(s)	B01.050.050.199.520.760.290 B01.050.150.900.649.313.992.635.505.700.400.290
Concept/Terms	Rats, Inbred OLETF Rats, Inbred OLETF Inbred OLETF Rat Inbred OLETF Rats OLETF Rat, Inbred OLETF Rats, Inbred Rat, Inbred OLETF Rats, OLETF OLETF Rat OLETF Rats Rat, OLETF Otsuka-Long-Evans-Tokushima Fatty Rats Fatty Rats, Otsuka-Long-Evans-Tokushima Otsuka Long Evans Tokushima Fatty Rats Rats, Otsuka-Long-Evans-Tokushima Fatty Otsuka-Long-Evans-Tokushima Rats Otsuka Long Evans Tokushima Rats Rats, Otsuka-Long-Evans-Tokushima

Below are MeSH descriptors whose meaning is more general than "Rats, Inbred OLETF".

Organisms [B]
Eukaryota [B01]
Animals [B01.050]
Animal Population Groups [B01.050.050]
Animals, Laboratory [B01.050.050.199]
Animals, Inbred Strains [B01.050.050.199.520]
Rats, Inbred Strains [B01.050.050.199.520.760]
Rats, Inbred OLETF [B01.050.050.199.520.760.290]
Chordata [B01.050.150]
Vertebrates [B01.050.150.900]
Mammals [B01.050.150.900.649]
Eutheria [B01.050.150.900.649.313]
Rodentia [B01.050.150.900.649.313.992]
Muridae [B01.050.150.900.649.313.992.635]
Murinae [B01.050.150.900.649.313.992.635.505]
Rats [B01.050.150.900.649.313.992.635.505.700]
Rats, Inbred Strains [B01.050.150.900.649.313.992.635.505.700.400]
Rats, Inbred OLETF [B01.050.150.900.649.313.992.635.505.700.400.290]

Below are MeSH descriptors whose meaning is related to "Rats, Inbred OLETF".

Below are MeSH descriptors whose meaning is more specific than "Rats, Inbred OLETF".

publications

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Below are the most recent publications written about "Rats, Inbred OLETF" by people in Profiles.

Panasevich MR, Schuster CM, Phillips KE, Meers GM, Chintapalli SV, Wankhade UD, Shankar K, Butteiger DN, Krul ES, Thyfault JP, Rector RS. Soy compared with milk protein in a Western diet changes fecal microbiota and decreases hepatic steatosis in obese OLETF rats. J Nutr Biochem. 2017 08; 46:125-136.

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Hinton PS, Shankar K, Eaton LM, Rector RS. Obesity-related changes in bone structural and material properties in hyperphagic OLETF rats and protection by voluntary wheel running. Metabolism. 2015 Aug; 64(8):905-16.

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Linden MA, Meers GM, Ruebel ML, Jenkins NT, Booth FW, Laughlin MH, Ibdah JA, Thyfault JP, Rector RS. Hepatic steatosis development with four weeks of physical inactivity in previously active, hyperphagic OLETF rats. Am J Physiol Regul Integr Comp Physiol. 2013 May 01; 304(9):R763-71.

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Mikus CR, Roseguini BT, Uptergrove GM, Morris EM, Rector RS, Libla JL, Oberlin DJ, Borengasser SJ, Taylor AM, Ibdah JA, Laughlin MH, Thyfault JP. Voluntary wheel running selectively augments insulin-stimulated vasodilation in arterioles from white skeletal muscle of insulin-resistant rats. Microcirculation. 2012 Nov; 19(8):729-38.

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Rector RS, Uptergrove GM, Morris EM, Borengasser SJ, Laughlin MH, Booth FW, Thyfault JP, Ibdah JA. Daily exercise vs. caloric restriction for prevention of nonalcoholic fatty liver disease in the OLETF rat model. Am J Physiol Gastrointest Liver Physiol. 2011 May; 300(5):G874-83.

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Rector RS, Uptergrove GM, Borengasser SJ, Mikus CR, Morris EM, Naples SP, Laye MJ, Laughlin MH, Booth FW, Ibdah JA, Thyfault JP. Changes in skeletal muscle mitochondria in response to the development of type 2 diabetes or prevention by daily wheel running in hyperphagic OLETF rats. Am J Physiol Endocrinol Metab. 2010 Jun; 298(6):E1179-87.

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Rector RS, Thyfault JP, Laye MJ, Morris RT, Borengasser SJ, Uptergrove GM, Chakravarthy MV, Booth FW, Ibdah JA. Cessation of daily exercise dramatically alters precursors of hepatic steatosis in Otsuka Long-Evans Tokushima Fatty (OLETF) rats. J Physiol. 2008 Sep 01; 586(17):4241-9.

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Rector RS, Thyfault JP, Morris RT, Laye MJ, Borengasser SJ, Booth FW, Ibdah JA. Daily exercise increases hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty rats. Am J Physiol Gastrointest Liver Physiol. 2008 Mar; 294(3):G619-26.

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