 MAP Kinase Kinase Kinase 5
"MAP Kinase Kinase Kinase 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 150-kDa MAP kinase kinase kinase that may play a role in the induction of APOPTOSIS. It has specificity for MAP KINASE KINASE 3; MAP KINASE KINASE 4; and MAP KINASE KINASE 6.
| Descriptor ID |
D048848
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| MeSH Number(s) |
D08.811.913.696.620.682.700.559.500 D12.644.360.400.500 D12.776.476.400.500
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| Concept/Terms |
MAP Kinase Kinase Kinase 5- MAP Kinase Kinase Kinase 5
- Apoptosis Signal-Regulating Kinase 1
- Apoptosis Signal Regulating Kinase 1
- MAPK Kinase Kinase 5
- MAP3K5 Protein Kinase
- Protein Kinase, MAP3K5
- Mitogen-Activated Kinase Kinase Kinase Kinase 5
- Mitogen Activated Kinase Kinase Kinase Kinase 5
- ASK1 Protein Kinase
- Protein Kinase, ASK1
- MAPKKK5
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Below are MeSH descriptors whose meaning is more general than "MAP Kinase Kinase Kinase 5".
Below are MeSH descriptors whose meaning is more specific than "MAP Kinase Kinase Kinase 5".
This graph shows the total number of publications written about "MAP Kinase Kinase Kinase 5" by people in this website by year, and whether "MAP Kinase Kinase Kinase 5" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "MAP Kinase Kinase Kinase 5" by people in Profiles.
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Liles JT, Corkey BK, Notte GT, Budas GR, Lansdon EB, Hinojosa-Kirschenbaum F, Badal SS, Lee M, Schultz BE, Wise S, Pendem S, Graupe M, Castonguay L, Koch KA, Wong MH, Papalia GA, French DM, Sullivan T, Huntzicker EG, Ma FY, Nikolic-Paterson DJ, Altuhaifi T, Yang H, Fogo AB, Breckenridge DG. ASK1 contributes to fibrosis and dysfunction in models of kidney disease. J Clin Invest. 2018 10 01; 128(10):4485-4500.
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Naik MU, Patel P, Derstine R, Turaga R, Chen X, Golla K, Neeves KB, Ichijo H, Naik UP. Ask1 regulates murine platelet granule secretion, thromboxane A2 generation, and thrombus formation. Blood. 2017 03 02; 129(9):1197-1209.
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Klawitter J, Klawitter J, Agardi E, Corby K, Leibfritz D, Lowes BD, Christians U, Seres T. Association of DJ-1/PTEN/AKT- and ASK1/p38-mediated cell signalling with ischaemic cardiomyopathy. Cardiovasc Res. 2013 Jan 01; 97(1):66-76.
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Basu S, Pathak SK, Banerjee A, Pathak S, Bhattacharyya A, Yang Z, Talarico S, Kundu M, Basu J. Execution of macrophage apoptosis by PE_PGRS33 of Mycobacterium tuberculosis is mediated by Toll-like receptor 2-dependent release of tumor necrosis factor-alpha. J Biol Chem. 2007 Jan 12; 282(2):1039-50.
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McLaughlin NJ, Banerjee A, Kelher MR, Gamboni-Robertson F, Hamiel C, Sheppard FR, Moore EE, Silliman CC. Platelet-activating factor-induced clathrin-mediated endocytosis requires beta-arrestin-1 recruitment and activation of the p38 MAPK signalosome at the plasma membrane for actin bundle formation. J Immunol. 2006 Jun 01; 176(11):7039-50.
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Srikanth S, Franklin CC, Duke RC, Kraft RS. Human DU145 prostate cancer cells overexpressing mitogen-activated protein kinase phosphatase-1 are resistant to Fas ligand-induced mitochondrial perturbations and cellular apoptosis. Mol Cell Biochem. 1999 Sep; 199(1-2):169-78.
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