 Thioacetamide
"Thioacetamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A crystalline compound used as a laboratory reagent in place of HYDROGEN SULFIDE. It is a potent hepatocarcinogen.
| Descriptor ID |
D013853
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| MeSH Number(s) |
D02.065.064.786 D02.065.900.890 D02.241.081.018.110.786 D02.886.685.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Thioacetamide".
Below are MeSH descriptors whose meaning is more specific than "Thioacetamide".
This graph shows the total number of publications written about "Thioacetamide" by people in this website by year, and whether "Thioacetamide" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thioacetamide" by people in Profiles.
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Sharma S, Mishra R, Walker BL, Deshmukh S, Zampino M, Patel J, Anamalai M, Simpson D, Singh IS, Kaushal S, Kaushal S. Celastrol, an oral heat shock activator, ameliorates multiple animal disease models of cell death. Cell Stress Chaperones. 2015 Jan; 20(1):185-201.
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Chilakapati J, Korrapati MC, Shankar K, Hill RA, Warbritton A, Latendresse JR, Mehendale HM. Role of CYP2E1 and saturation kinetics in the bioactivation of thioacetamide: Effects of diet restriction and phenobarbital. Toxicol Appl Pharmacol. 2007 Feb 15; 219(1):72-84.
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Chilakapati J, Shankar K, Korrapati MC, Hill RA, Mehendale HM. Saturation toxicokinetics of thioacetamide: role in initiation of liver injury. Drug Metab Dispos. 2005 Dec; 33(12):1877-85.
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Shankar K, Vaidya VS, Wang T, Bucci TJ, Mehendale HM. Streptozotocin-induced diabetic mice are resistant to lethal effects of thioacetamide hepatotoxicity. Toxicol Appl Pharmacol. 2003 Apr 15; 188(2):122-34.
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Wang T, Shankar K, Bucci TJ, Warbritton A, Mehendale HM. Diallyl sulfide inhibition of CYP2E1 does not rescue diabetic rats from thioacetamide-induced mortality. Toxicol Appl Pharmacol. 2001 May 15; 173(1):27-37.
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Wang T, Shankar K, Ronis MJ, Mehendale HM. Potentiation of thioacetamide liver injury in diabetic rats is due to induced CYP2E1. J Pharmacol Exp Ther. 2000 Aug; 294(2):473-9.
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