 Convulsants
"Convulsants" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Substances that act in the brain stem or spinal cord to produce tonic or clonic convulsions, often by removing normal inhibitory tone. They were formerly used to stimulate respiration or as antidotes to barbiturate overdose. They are now most commonly used as experimental tools.
| Descriptor ID |
D003292
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| MeSH Number(s) |
D27.505.696.282.224 D27.505.954.427.220.224
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| Concept/Terms |
Convulsant Effect- Convulsant Effect
- Effect, Convulsant
- Convulsant Effects
- Effects, Convulsant
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Below are MeSH descriptors whose meaning is more general than "Convulsants".
Below are MeSH descriptors whose meaning is more specific than "Convulsants".
This graph shows the total number of publications written about "Convulsants" by people in this website by year, and whether "Convulsants" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 | | 1998 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Convulsants" by people in Profiles.
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Grabenstatter HL, Dudek FE. Effect of carbamazepine on spontaneous recurrent seizures recorded from the dentate gyrus in rats with kainate-induced epilepsy. Epilepsia. 2019 04; 60(4):636-647.
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Hamilton LR, Schachter SC, Myers TM. Time Course, Behavioral Safety, and Protective Efficacy of Centrally Active Reversible Acetylcholinesterase Inhibitors in Cynomolgus Macaques. Neurochem Res. 2017 Jul; 42(7):1962-1971.
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Frey L, Lepkin A, Schickedanz A, Huber K, Brown MS, Serkova N. ADC mapping and T1-weighted signal changes on post-injury MRI predict seizure susceptibility after experimental traumatic brain injury. Neurol Res. 2014 Jan; 36(1):26-37.
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Zhang G, Raol YS, Hsu FC, Brooks-Kayal AR. Long-term alterations in glutamate receptor and transporter expression following early-life seizures are associated with increased seizure susceptibility. J Neurochem. 2004 Jan; 88(1):91-101.
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Will MJ, Watkins LR, Maier SF. Uncontrollable stress potentiates morphine's rewarding properties. Pharmacol Biochem Behav. 1998 Jul; 60(3):655-64.
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Todorovic SM, Lingle CJ. Pharmacological properties of T-type Ca2+ current in adult rat sensory neurons: effects of anticonvulsant and anesthetic agents. J Neurophysiol. 1998 Jan; 79(1):240-52.
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Grahn RE, Kalman BA, Brennan FX, Watkins LR, Maier SF. The elevated plus-maze is not sensitive to the effect of stressor controllability in rats. Pharmacol Biochem Behav. 1995 Nov; 52(3):565-70.
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Maier SF, Busch CR, Maswood S, Grahn RE, Watkins LR. The dorsal raphe nucleus is a site of action mediating the behavioral effects of the benzodiazepine receptor inverse agonist DMCM. Behav Neurosci. 1995 Aug; 109(4):759-66.
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Fleshner M, Brohm MM, Laudenslager ML, Watkins LR, Maier SF. Modulation of the in vivo antibody response by a benzodiazepine inverse agonist (DMCM) administered centrally or peripherally. Physiol Behav. 1993 Dec; 54(6):1149-54.
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Melchior CL, Garrett KM, Tabakoff B. A benzodiazepine antagonist action of CL 218,872. Life Sci. 1984 May 28; 34(22):2201-6.
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