Tolazoline
"Tolazoline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
| Descriptor ID |
D014043
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| MeSH Number(s) |
D03.383.129.308.436.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tolazoline".
Below are MeSH descriptors whose meaning is more specific than "Tolazoline".
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Below are the most recent publications written about "Tolazoline" by people in Profiles.
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Abman SH, Wilkening RB, Ward RM, Accurso FJ. Adaptation of fetal pulmonary blood flow to local infusion of tolazoline. Pediatr Res. 1986 Nov; 20(11):1131-5.
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Miller DD, Hamada A, Craig EC, Christoph GG, Gallucci JC, Rice PJ, Banning JW, Patil PN. Optically active catecholimidazolines: a study of steric interactions at alpha-adrenoreceptors. J Med Chem. 1983 Jul; 26(7):957-63.