Rhodamine 123
"Rhodamine 123" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fluorescent probe with low toxicity which is a potent substrate for ATP-BINDING CASSETTE, SUB-FAMILY B, MEMBER 1 and the bacterial multidrug efflux transporter. It is used to assess mitochondrial bioenergetics in living cells and to measure the efflux activity of ATP-BINDING CASSETTE, SUB-FAMILY B, MEMBER 1 in both normal and malignant cells. (Leukemia 1997;11(7):1124-30)
Descriptor ID |
D020112
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MeSH Number(s) |
D03.633.300.953.600.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Rhodamine 123".
Below are MeSH descriptors whose meaning is more specific than "Rhodamine 123".
This graph shows the total number of publications written about "Rhodamine 123" by people in this website by year, and whether "Rhodamine 123" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 | 2001 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Rhodamine 123" by people in Profiles.
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Wempe MF, Wright C, Little JL, Lightner JW, Large SE, Caflisch GB, Buchanan CM, Rice PJ, Wacher VJ, Ruble KM, Edgar KJ. Inhibiting efflux with novel non-ionic surfactants: Rational design based on vitamin E TPGS. Int J Pharm. 2009 Mar 31; 370(1-2):93-102.
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Collnot EM, Baldes C, Wempe MF, Hyatt J, Navarro L, Edgar KJ, Schaefer UF, Lehr CM. Influence of vitamin E TPGS poly(ethylene glycol) chain length on apical efflux transporters in Caco-2 cell monolayers. J Control Release. 2006 Mar 10; 111(1-2):35-40.
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Ng KY, Cho CW, Henthorn TK, Tanguay RL. Effect of heat preconditioning on the uptake and permeability of R123 in brain microvessel endothelial cells during mild heat treatment. J Pharm Sci. 2004 Apr; 93(4):896-907.
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Liu Y, Lillehei K, Cobb WN, Christians U, Ng KY. Overcoming MDR by ultrasound-induced hyperthermia and P-glycoprotein modulation. Biochem Biophys Res Commun. 2001 Nov 23; 289(1):62-8.
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Cho CW, Liu Y, Yan X, Henthorn T, Ng KY. Carrier-mediated uptake of rhodamine 123: implications on its use for MDR research. Biochem Biophys Res Commun. 2000 Dec 09; 279(1):124-30.
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Van Blerkom J, Davis P, Alexander S. Differential mitochondrial distribution in human pronuclear embryos leads to disproportionate inheritance between blastomeres: relationship to microtubular organization, ATP content and competence. Hum Reprod. 2000 Dec; 15(12):2621-33.
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