Phosgene
"Phosgene" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly toxic gas that has been used as a chemical warfare agent. It is an insidious poison as it is not irritating immediately, even when fatal concentrations are inhaled. (From The Merck Index, 11th ed, p7304)
Descriptor ID |
D010705
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MeSH Number(s) |
D02.522.741
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phosgene".
Below are MeSH descriptors whose meaning is more specific than "Phosgene".
This graph shows the total number of publications written about "Phosgene" by people in this website by year, and whether "Phosgene" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2017 | 2 | 0 | 2 | 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosgene" by people in Profiles.
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Goswami DG, Singh SK, Okoyeocha EOM, Roney AK, Madadgar O, Tuttle R, Sosna W, Anantharam P, Croutch CR, Agarwal R, Tewari-Singh N. Dermal Exposure to Vesicating Nettle Agent Phosgene Oxime: Clinically Relevant Biomarkers and Skin Injury Progression in Murine Models. J Pharmacol Exp Ther. 2024 01 17; 388(2):536-545.
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Goswami DG, Agarwal R, Tewari-Singh N. Phosgene oxime: Injury and associated mechanisms compared to vesicating agents sulfur mustard and lewisite. Toxicol Lett. 2018 Sep 01; 293:112-119.
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Tewari-Singh N, Goswami DG, Kant R, Croutch CR, Casillas RP, Orlicky DJ, Agarwal R. Cutaneous exposure to vesicant phosgene oxime: Acute effects on the skin and systemic toxicity. Toxicol Appl Pharmacol. 2017 02 15; 317:25-32.
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Pohl LR, Schulick RD, Highet RJ, George JW. Reductive-oxygenation mechanism of metabolism of carbon tetrachloride to phosgene by cytochrome P-450. Mol Pharmacol. 1984 Mar; 25(2):318-21.
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Branchflower RV, Schulick RD, George JW, Pohl LR. Comparison of the effects of methyl-N-butyl ketone and phenobarbital on rat liver cytochromes P-450 and the metabolism of chloroform to phosgene. Toxicol Appl Pharmacol. 1983 Dec; 71(3):414-21.
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