Tocolytic Agents
"Tocolytic Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that prevent preterm labor and immature birth by suppressing uterine contractions (TOCOLYSIS). Agents used to delay premature uterine activity include magnesium sulfate, beta-mimetics, oxytocin antagonists, calcium channel inhibitors, and adrenergic beta-receptor agonists. The use of intravenous alcohol as a tocolytic is now obsolete.
Descriptor ID |
D015149
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MeSH Number(s) |
D27.505.696.875.825 D27.505.954.705.825
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Concept/Terms |
Tocolytic Effect- Tocolytic Effect
- Effect, Tocolytic
- Tocolytic Effects
- Effects, Tocolytic
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Below are MeSH descriptors whose meaning is more general than "Tocolytic Agents".
Below are MeSH descriptors whose meaning is more specific than "Tocolytic Agents".
This graph shows the total number of publications written about "Tocolytic Agents" by people in this website by year, and whether "Tocolytic Agents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 2004 | 2 | 0 | 2 | 2006 | 1 | 0 | 1 | 2008 | 1 | 0 | 1 | 2009 | 0 | 1 | 1 | 2010 | 1 | 0 | 1 | 2011 | 0 | 1 | 1 | 2015 | 0 | 1 | 1 | 2017 | 0 | 1 | 1 | 2018 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tocolytic Agents" by people in Profiles.
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Hanley M, Sayres L, Reiff ES, Wood A, Grotegut CA, Kuller JA. Tocolysis: A Review of the Literature. Obstet Gynecol Surv. 2019 Jan; 74(1):50-55.
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Howley LW, Chatterjee D, Patel SS, Cuneo BF, Crombleholme TM, Behrendt N, Zaretsky MV, Marwan AI, Zuk J, Galan HL, Wood C. Indomethacin Dosing and Constriction of the Ductus Arteriosus During Open Fetal Surgery for Myelomeningocele Repair. Fetal Diagn Ther. 2019; 45(5):339-344.
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Sharma V, Nair SV, Jaitley P, Nakade UP, Sharma A, Choudhury S, Garg SK. ATP-sensitive and maxi potassium channels regulate BRL 37344-induced tocolysis in buffaloes-an in?vitro study. Theriogenology. 2018 Feb; 107:194-202.
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Alston MJ, Alexandrovic K, Stiglich N, Metz TD. Discontinuation of Tocolytics for Preterm Labor in an Academic Safety Net Hospital: Impact on the Duration of Betamethasone Exposure. J Reprod Med. 2016 Mar-Apr; 61(3-4):109-13.
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Faucett AM, Metz TD, DeWitt PE, Gibbs RS. Effect of obesity on neonatal outcomes in pregnancies with preterm premature rupture of membranes. Am J Obstet Gynecol. 2016 Feb; 214(2):287.e1-287.e5.
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Reeves SA, Gibbs RS, Clark SL. Magnesium for fetal neuroprotection. Am J Obstet Gynecol. 2011 Mar; 204(3):202.e1-4.
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Ridge AL, Bero LA, Hill SR. Identifying barriers to the availability and use of Magnesium Sulphate Injection in resource poor countries: a case study in Zambia. BMC Health Serv Res. 2010 Dec 16; 10:340.
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Bastek JA, Srinivas SK, Sammel MD, Elovitz MA. Do neonatal outcomes differ depending on the cause of preterm birth? A comparison between spontaneous birth and iatrogenic delivery for preeclampsia. Am J Perinatol. 2010 Feb; 27(2):163-9.
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Olson DM, Christiaens I, Gracie S, Yamamoto Y, Mitchell BF. Emerging tocolytics: challenges in designing and testing drugs to delay preterm delivery and prolong pregnancy. Expert Opin Emerg Drugs. 2008 Dec; 13(4):695-707.
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Heyborne K. Magnesium sulfate tocolysis: time to quit. Obstet Gynecol. 2007 Feb; 109(2 Pt 1):450; author reply 451.
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