 Calcimycin
"Calcimycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.
| Descriptor ID |
D000001
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| MeSH Number(s) |
D03.633.100.221.173
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| Concept/Terms |
A-23187- A-23187
- A 23187
- A23187
- Antibiotic A23187
- A23187, Antibiotic
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Below are MeSH descriptors whose meaning is more general than "Calcimycin".
Below are MeSH descriptors whose meaning is more specific than "Calcimycin".
This graph shows the total number of publications written about "Calcimycin" by people in this website by year, and whether "Calcimycin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 | | 1995 | 0 | 3 | 3 | | 1996 | 1 | 5 | 6 | | 1997 | 0 | 2 | 2 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 4 | 4 | | 2000 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2003 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2008 | 0 | 2 | 2 | | 2009 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Calcimycin" by people in Profiles.
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Yun B, Lee H, Ewing H, Gelb MH, Leslie CC. Off-target effect of the cPLA2a inhibitor pyrrophenone: Inhibition of calcium release from the endoplasmic reticulum. Biochem Biophys Res Commun. 2016 10 07; 479(1):61-6.
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Zarini S, Hankin JA, Murphy RC, Gij?n MA. Lysophospholipid acyltransferases and eicosanoid biosynthesis in zebrafish myeloid cells. Prostaglandins Other Lipid Mediat. 2014 Oct; 113-115:52-61.
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Barajas-Espinosa A, Ni NC, Yan D, Zarini S, Murphy RC, Funk CD. The cysteinyl leukotriene 2 receptor mediates retinal edema and pathological neovascularization in a murine model of oxygen-induced retinopathy. FASEB J. 2012 Mar; 26(3):1100-9.
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Talahalli R, Zarini S, Sheibani N, Murphy RC, Gubitosi-Klug RA. Increased synthesis of leukotrienes in the mouse model of diabetic retinopathy. Invest Ophthalmol Vis Sci. 2010 Mar; 51(3):1699-708.
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Berry KA, Henson PM, Murphy RC. Effects of acrolein on leukotriene biosynthesis in human neutrophils. Chem Res Toxicol. 2008 Dec; 21(12):2424-32.
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Zharikov S, Krotova K, Hu H, Baylis C, Johnson RJ, Block ER, Patel J. Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells. Am J Physiol Cell Physiol. 2008 Nov; 295(5):C1183-90.
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Tucker DE, Gij?n MA, Spencer DM, Qiu ZH, Gelb MH, Leslie CC. Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages. J Leukoc Biol. 2008 Sep; 84(3):798-806.
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Sanderson MP, Abbott CA, Tada H, Seno M, Dempsey PJ, Dunbar AJ. Hydrogen peroxide and endothelin-1 are novel activators of betacellulin ectodomain shedding. J Cell Biochem. 2006 Oct 01; 99(2):609-23.
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Zarini S, Gij?n MA, Folco G, Murphy RC. Effect of arachidonic acid reacylation on leukotriene biosynthesis in human neutrophils stimulated with granulocyte-macrophage colony-stimulating factor and formyl-methionyl-leucyl-phenylalanine. J Biol Chem. 2006 Apr 14; 281(15):10134-42.
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Zemski Berry KA, Murphy RC. Analysis of polyunsaturated aminophospholipid molecular species using isotope-tagged derivatives and tandem mass spectrometry/mass spectrometry/mass spectrometry. Anal Biochem. 2006 Feb 01; 349(1):118-28.
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