 Sickle Cell Trait
"Sickle Cell Trait" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The condition of being heterozygous for hemoglobin S.
| Descriptor ID |
D012805
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| MeSH Number(s) |
C15.378.071.141.150.150.670 C15.378.420.155.668 C16.320.070.150.670 C16.320.365.155.668
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| Concept/Terms |
Sickle Cell Trait- Sickle Cell Trait
- Cell Trait, Sickle
- Cell Traits, Sickle
- Sickle Cell Traits
- Trait, Sickle Cell
- Traits, Sickle Cell
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Below are MeSH descriptors whose meaning is more general than "Sickle Cell Trait".
- Diseases [C]
- Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
- Anemia [C15.378.071]
- Anemia, Hemolytic [C15.378.071.141]
- Anemia, Hemolytic, Congenital [C15.378.071.141.150]
- Anemia, Sickle Cell [C15.378.071.141.150.150]
- Sickle Cell Trait [C15.378.071.141.150.150.670]
- Hemoglobinopathies [C15.378.420]
- Anemia, Sickle Cell [C15.378.420.155]
- Sickle Cell Trait [C15.378.420.155.668]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Anemia, Hemolytic, Congenital [C16.320.070]
- Anemia, Sickle Cell [C16.320.070.150]
- Sickle Cell Trait [C16.320.070.150.670]
- Hemoglobinopathies [C16.320.365]
- Anemia, Sickle Cell [C16.320.365.155]
- Sickle Cell Trait [C16.320.365.155.668]
Below are MeSH descriptors whose meaning is more specific than "Sickle Cell Trait".
This graph shows the total number of publications written about "Sickle Cell Trait" by people in this website by year, and whether "Sickle Cell Trait" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2023 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Sickle Cell Trait" by people in Profiles.
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D'Alessandro A, Nouraie SM, Zhang Y, Cendali F, Gamboni F, Reisz JA, Zhang X, Bartsch KW, Galbraith MD, Gordeuk VR, Gladwin MT. In vivo evaluation of the effect of sickle cell hemoglobin S, C and therapeutic transfusion on erythrocyte metabolism and cardiorenal dysfunction. Am J Hematol. 2023 07; 98(7):1017-1028.
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Reiner AP, Raffield LM, Franceschini N, Auer PL, Lange EM, Nickerson DA, Zakai NA, Correa A, Olson N. Effect of Sickle Cell Trait and APOL1 Genotype on the Association of Soluble uPAR with Kidney Function Measures in Black Americans. Clin J Am Soc Nephrol. 2021 Feb 08; 16(2):287-289.
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Douce DR, Soliman EZ, Naik R, Hyacinth HI, Cushman M, Winkler CA, Howard G, Lange EM, Lange LA, Irvin MR, Zakai NA. Association of sickle cell trait with atrial fibrillation: The REGARDS cohort. J Electrocardiol. 2019 Jul - Aug; 55:1-5.
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Naik RP, Smith-Whitley K, Hassell KL, Umeh NI, de Montalembert M, Sahota P, Haywood C, Jenkins J, Lloyd-Puryear MA, Joiner CH, Bonham VL, Kato GJ. Clinical Outcomes Associated With Sickle Cell Trait: A Systematic Review. Ann Intern Med. 2018 11 06; 169(9):619-627.
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Raffield LM, Ulirsch JC, Naik RP, Lessard S, Handsaker RE, Jain D, Kang HM, Pankratz N, Auer PL, Bao EL, Smith JD, Lange LA, Lange EM, Li Y, Thornton TA, Young BA, Abecasis GR, Laurie CC, Nickerson DA, McCarroll SA, Correa A, Wilson JG, Lettre G, Sankaran VG, Reiner AP. Common a-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease. PLoS Genet. 2018 03; 14(3):e1007293.
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Raffield LM, Zakai NA, Duan Q, Laurie C, Smith JD, Irvin MR, Doyle MF, Naik RP, Song C, Manichaikul AW, Liu Y, Durda P, Rotter JI, Jenny NS, Rich SS, Wilson JG, Johnson AD, Correa A, Li Y, Nickerson DA, Rice K, Lange EM, Cushman M, Lange LA, Reiner AP. D-Dimer in African Americans: Whole Genome Sequence Analysis and Relationship to Cardiovascular Disease Risk in the Jackson Heart Study. Arterioscler Thromb Vasc Biol. 2017 11; 37(11):2220-2227.
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Osei-Hwedieh DO, Kanias T, Croix CS, Jessup M, Xiong Z, Sinchar D, Franks J, Xu Q, M Novelli E, Sertorio JT, Potoka K, Binder RJ, Basu S, Belanger AM, Kim-Shapiro DB, Triulzi D, Lee JS, Gladwin MT. Sickle Cell Trait Increases Red Blood Cell Storage Hemolysis and Post-Transfusion Clearance in Mice. EBioMedicine. 2016 Sep; 11:239-248.
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Goodman J, Hassell K, Irwin D, Witkowski EH, Nuss R. The splenic syndrome in individuals with sickle cell trait. High Alt Med Biol. 2014 Dec; 15(4):468-71.
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Buckner TW, Key NS. Venous thrombosis in blacks. Circulation. 2012 Feb 14; 125(6):837-9.
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Field JJ, Strunk RC, Knight-Perry JE, Blinder MA, Townsend RR, DeBaun MR. Urinary cysteinyl leukotriene E4 significantly increases during pain in children and adults with sickle cell disease. Am J Hematol. 2009 Apr; 84(4):231-3.
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