Hydroxychloroquine
"Hydroxychloroquine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
Descriptor ID |
D006886
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MeSH Number(s) |
D03.633.100.810.050.180.350
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hydroxychloroquine".
Below are MeSH descriptors whose meaning is more specific than "Hydroxychloroquine".
This graph shows the total number of publications written about "Hydroxychloroquine" by people in this website by year, and whether "Hydroxychloroquine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 0 | 1 | 1999 | 2 | 0 | 2 | 2002 | 1 | 1 | 2 | 2012 | 0 | 2 | 2 | 2013 | 0 | 5 | 5 | 2014 | 1 | 0 | 1 | 2016 | 0 | 1 | 1 | 2017 | 2 | 1 | 3 | 2018 | 0 | 1 | 1 | 2019 | 1 | 0 | 1 | 2020 | 4 | 3 | 7 | 2021 | 3 | 2 | 5 | 2022 | 1 | 4 | 5 | 2023 | 1 | 1 | 2 |
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Below are the most recent publications written about "Hydroxychloroquine" by people in Profiles.
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Libman I, Bingley PJ, Becker D, Buckner JH, DiMeglio LA, Gitelman SE, Greenbaum C, Haller MJ, Ismail HM, Krischer J, Moore WV, Moran A, Muir AB, Raman V, Steck AK, Toledo FGS, Wentworth J, Wherrett D, White P, You L, Herold KC. Hydroxychloroquine in Stage 1 Type 1 Diabetes. Diabetes Care. 2023 11 01; 46(11):2035-2043.
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Bartels CM, Jorge A, Feldman CH, Zell J, Bermas B, Barber CEH, Duarte-Garc?a A, Garg S, Haseley L, Jatwani S, Johansson T, Limanni A, Rodgers W, Rovin BH, Santiago-Casas Y, Suter LG, Barnado A, Ude J, Aguirre A, Li J, Schmajuk G, Yazdany J. Development of American College of Rheumatology Quality Measures for Systemic Lupus Erythematosus: A Modified Delphi Process With Rheumatology Informatics System for Effectiveness (RISE) Registry Data Review. Arthritis Care Res (Hoboken). 2023 11; 75(11):2295-2305.
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Khan R, Panja S, Ding L, Tang S, Tang W, Kapoor E, Bennett RG, Oupick? D. Polymeric Chloroquine as an Effective Antimigration Agent in the Treatment of Pancreatic Cancer. Mol Pharm. 2022 12 05; 19(12):4631-4643.
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Cruz MA, Bohinc D, Andraska EA, Alvikas J, Raghunathan S, Masters NA, van Kleef ND, Bane KL, Hart K, Medrow K, Sun M, Liu H, Haldeman S, Banerjee A, Lessieur EM, Hageman K, Gandhi A, de la Fuente M, Nieman MT, Kern TS, Maas C, de Maat S, Neeves KB, Neal MD, Sen Gupta A, Stavrou EX. Nanomedicine platform for targeting activated neutrophils and neutrophil-platelet complexes using an a1-antitrypsin-derived peptide motif. Nat Nanotechnol. 2022 09; 17(9):1004-1014.
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Griswold MK, Chai PR, Brent J, Weiss S, Askman N, Wax PM, Farrugia LA. Hydroxychloroquine and Chloroquine Toxicity as Reported by Medical Toxicologists to the Toxicology Investigators Consortium (ToxIC) Registry. J Med Toxicol. 2022 07; 18(3):256-259.
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Mondal K, Porter H, Cole J, Pandya HK, Basu SK, Khanam S, Chiu CY, Shah V, Stephenson DJ, Chalfant CE, Mandal N. Hydroxychloroquine Causes Early Inner Retinal Toxicity and Affects Autophagosome-Lysosomal Pathway and Sphingolipid Metabolism in the Retina. Mol Neurobiol. 2022 Jun; 59(6):3873-3887.
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Kaizer AM, Wild J, Lindsell CJ, Rice TW, Self WH, Brown S, Thompson BT, Hart KW, Smith C, Pulia MS, Shapiro NI, Ginde AA. Trial of Early Antiviral Therapies during Non-hospitalized Outpatient Window (TREAT NOW) for COVID-19: a summary of the protocol and analysis plan for a decentralized randomized controlled trial. Trials. 2022 Apr 08; 23(1):273.
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Croci S, Venneri MA, Mantovani S, Fallerini C, Benetti E, Picchiotti N, Campolo F, Imperatore F, Palmieri M, Daga S, Gabbi C, Montagnani F, Beligni G, Farias TDJ, Carriero ML, Di Sarno L, Alaverdian D, Aslaksen S, Cubellis MV, Spiga O, Baldassarri M, Fava F, Norman PJ, Frullanti E, Isidori AM, Amoroso A, Mari F, Furini S, Mondelli MU, Chiariello M, Renieri A, Meloni I. The polymorphism L412F in TLR3 inhibits autophagy and is a marker of severe COVID-19 in males. Autophagy. 2022 07; 18(7):1662-1672.
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Mehta HB, An H, Andersen KM, Mansour O, Madhira V, Rashidi ES, Bates B, Setoguchi S, Joseph C, Kocis PT, Moffitt R, Bennett TD, Chute CG, Garibaldi BT, Alexander GC. Use of Hydroxychloroquine, Remdesivir, and Dexamethasone Among Adults Hospitalized With COVID-19 in the United States : A Retrospective Cohort Study. Ann Intern Med. 2021 10; 174(10):1395-1403.
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Bradley SM, Emmons-Bell S, Mutharasan RK, Rodriguez F, Gupta D, Roth G, Gluckman TJ, Shah RU, Wang TY, Khera R, Peterson PN, Das S. Repeated cross-sectional analysis of hydroxychloroquine deimplementation in the AHA COVID-19 CVD Registry. Sci Rep. 2021 07 23; 11(1):15097.
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