 Phosphofructokinase-1
"Phosphofructokinase-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, TYPE C; found in platelets, brain, and other tissues.
| Descriptor ID |
D010732
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| MeSH Number(s) |
D08.811.913.696.620.225.850.500
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| Concept/Terms |
Phosphofructokinase-1- Phosphofructokinase-1
- Phosphofructokinase 1
- 6-Phosphofructokinase
- 6 Phosphofructokinase
- Fructose-6-phosphate 1-Phosphotransferase
- 6-Phosphofructo-1-kinase
- Fructose-6-P 1-Kinase
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Below are MeSH descriptors whose meaning is more general than "Phosphofructokinase-1".
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This graph shows the total number of publications written about "Phosphofructokinase-1" by people in this website by year, and whether "Phosphofructokinase-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phosphofructokinase-1" by people in Profiles.
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Aguilo F, Li S, Balasubramaniyan N, Sancho A, Benko S, Zhang F, Vashisht A, Rengasamy M, Andino B, Chen CH, Zhou F, Qian C, Zhou MM, Wohlschlegel JA, Zhang W, Suchy FJ, Walsh MJ. Deposition of 5-Methylcytosine on Enhancer RNAs Enables the Coactivator Function of PGC-1a. Cell Rep. 2016 Jan 26; 14(3):479-492.
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Bruns DR, Brown RD, Stenmark KR, Buttrick PM, Walker LA. Mitochondrial integrity in a neonatal bovine model of right ventricular dysfunction. Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15; 308(2):L158-67.
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Dourmashkin JT, Chang GQ, Gayles EC, Hill JO, Fried SK, Julien C, Leibowitz SF. Different forms of obesity as a function of diet composition. Int J Obes (Lond). 2005 Nov; 29(11):1368-78.
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Houle-Leroy P, Garland T, Swallow JG, Guderley H. Effects of voluntary activity and genetic selection on muscle metabolic capacities in house mice Mus domesticus. J Appl Physiol (1985). 2000 Oct; 89(4):1608-16.
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Gayles EC, Pagliassotti MJ, Prach PA, Koppenhafer TA, Hill JO. Contribution of energy intake and tissue enzymatic profile to body weight gain in high-fat-fed rats. Am J Physiol. 1997 Jan; 272(1 Pt 2):R188-94.
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Dong A, Prestrelski SJ, Allison SD, Carpenter JF. Infrared spectroscopic studies of lyophilization- and temperature-induced protein aggregation. J Pharm Sci. 1995 Apr; 84(4):415-24.
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Jones JP, MacLean PS, Winder WW. Correlation between fructose 2,6-bisphosphate and lactate production in skeletal muscle. J Appl Physiol (1985). 1994 May; 76(5):2169-76.
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Carpenter JF, Prestrelski SJ, Arakawa T. Separation of freezing- and drying-induced denaturation of lyophilized proteins using stress-specific stabilization. I. Enzyme activity and calorimetric studies. Arch Biochem Biophys. 1993 Jun; 303(2):456-64.
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Prestrelski SJ, Arakawa T, Carpenter JF. Separation of freezing- and drying-induced denaturation of lyophilized proteins using stress-specific stabilization. II. Structural studies using infrared spectroscopy. Arch Biochem Biophys. 1993 Jun; 303(2):465-73.
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Carpenter JF, Crowe JH. An infrared spectroscopic study of the interactions of carbohydrates with dried proteins. Biochemistry. 1989 May 02; 28(9):3916-22.
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