Nitric oxide produced by cytochrome c oxidase helps stabilize HIF-1a in hypoxic mammalian cells.
Ball KA, Nelson AW, Foster DG, Poyton RO. Nitric oxide produced by cytochrome c oxidase helps stabilize HIF-1a in hypoxic mammalian cells. Biochem Biophys Res Commun. 2012 Apr 20; 420(4):727-32.