Shc is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21ras-GTP formation.

Sasaoka T, Draznin B, Leitner JW, Langlois WJ, Olefsky JM. Shc is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21ras-GTP formation. J Biol Chem. 1994 Apr 08; 269(14):10734-8.

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subject areas

Adaptor Proteins, Signal Transducing
Adaptor Proteins, Vesicular Transport
Animals
Cells, Cultured
GRB2 Adaptor Protein
Guanine Nucleotide Exchange Factors
Guanosine Triphosphate
Insulin Receptor Substrate Proteins
Kinetics
Oncogene Protein p21(ras)
Phosphoproteins
Proteins
ras Guanine Nucleotide Exchange Factors
Rats
Receptor, Insulin
Shc Signaling Adaptor Proteins
Signal Transduction
Src Homology 2 Domain-Containing, Transforming Protein 1

authors with profiles

Boris Draznin