 Swati Ghosh
| Title | Research Instructor |
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| Institution | University of Colorado Denver - Anschutz Medical Campus |
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| Department | SOM-PEDS |
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ORCID
.gif) | 0000-0002-1902-8025  |
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 Biography | 2022 - 2023 | Principal Investigator, CCTSI Child and Maternal Health Pilot Grant Program (CMH-Pilot) Grant | | 2023 - 2024 | Principal Investigator , NIDDK ( Childhood liver disease research network) |
Overview - Macrophage, Liver, HIF1, LRH-1 ,FXR ,signaing Hepatocytes, Cholangiocytes, NGS, ChiP, RNA seq,
Bibliographic
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Ghosh S, Devereaux MW, Liu C, Sokol RJ. LRH-1 agonist DLPC through STAT6 promotes macrophage polarization and prevents parenteral nutrition-associated cholestasis in mice. Hepatology. 2024 05 01; 79(5):986-1004. PMID: 37976384.
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Ghosh S, Devereaux MW, Orlicky DJ, Sokol RJ. Publisher Correction: Pharmacologic inhibition of HNF4a prevents parenteral nutrition associated cholestasis in mice. Sci Rep. 2023 Jul 19; 13(1):11673. PMID: 37468479.
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Ghosh S, Devereaux MW, Orlicky DJ, Sokol RJ. Pharmacologic inhibition of HNF4a prevents parenteral nutrition associated cholestasis in mice. Sci Rep. 2023 05 12; 13(1):7752. PMID: 37173326.
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Ghosh S, Devereaux MW, Anderson AL, El Kasmi KC, Sokol RJ. Stat3 role in the protective effect of FXR Agonist in parenteral nutrition-associated cholestasis. Hepatol Commun. 2023 03 01; 7(3):e0056. PMID: 36848082.
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El Kasmi KC, Ghosh S, Anderson AL, Devereaux MW, Balasubramaniyan N, D'Alessandro A, Orlicky DJ, Suchy FJ, Shearn CT, Sokol RJ. Pharmacologic activation of hepatic farnesoid X receptor prevents parenteral nutrition-associated cholestasis in mice. Hepatology. 2022 02; 75(2):252-265. PMID: 34387888.
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Jo JR, An S, Ghosh S, Nedumaran B, Kim YD. Growth hormone promotes hepatic gluconeogenesis by enhancing BTG2-YY1 signaling pathway. Sci Rep. 2021 09 23; 11(1):18999. PMID: 34556771.
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Ghosh S, Devereaux MW, Anderson AL, Gehrke S, Reisz JA, D'Alessandro A, Orlicky DJ, Lovell M, El Kasmi KC, Shearn CT, Sokol RJ. NF-?B Regulation of LRH-1 and ABCG5/8 Potentiates Phytosterol Role in the Pathogenesis of Parenteral Nutrition-Associated Cholestasis. Hepatology. 2021 12; 74(6):3284-3300. PMID: 34310734.
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Jo JR, Lee SE, An S, Nedumaran B, Ghosh S, Park KG, Kim YD. Gluconeogenic signals regulate hepcidin gene expression via a CRBN-KLF15 axis. BMB Rep. 2021 04; 54(4):221-226. PMID: 33795032.
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Swati Ghosh, Aimee Anderson, Michael Devereaux, Karim C El Kasmi, Ronald J Sokol. STAT3 Signaling May Mediate Protective Effect Of FXR Agonist IN Parental Nutrition Associated Cholestasis. 2020; 72(HEPATOLOGY):48A-49A.
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Swati Ghosh, Aimee L Anderson, Michael W Devereaux, Ronald J Sokol. Targeting HNF4 alpha IN NFKB-Activated Parenteral Nutrition Associated Cholestasis. 2019; 70:470A-470A.
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El Kasmi KC, Vue PM, Anderson AL, Devereaux MW, Ghosh S, Balasubramaniyan N, Fillon SA, Dahrenmoeller C, Allawzi A, Woods C, McKenna S, Wright CJ, Johnson L, D'Alessandro A, Reisz JA, Nozik-Grayck E, Suchy FJ, Sokol RJ. Macrophage-derived IL-1?/NF-?B signaling mediates parenteral nutrition-associated cholestasis. Nat Commun. 2018 04 11; 9(1):1393. PMID: 29643332.
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Cinghu S, Yellaboina S, Freudenberg JM, Ghosh S, Zheng X, Oldfield AJ, Lackford BL, Zaykin DV, Hu G, Jothi R. Integrative framework for identification of key cell identity genes uncovers determinants of ES cell identity and homeostasis. Proc Natl Acad Sci U S A. 2014 Apr 22; 111(16):E1581-90. PMID: 24711389.
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Freudenberg JM, Ghosh S, Lackford BL, Yellaboina S, Zheng X, Li R, Cuddapah S, Wade PA, Hu G, Jothi R. Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity. Nucleic Acids Res. 2012 Apr; 40(8):3364-77. PMID: 22210859.
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Ghosh S, Thakur MK. Age-dependent decrease in the interaction of beta-tubulin with estrogen receptor alpha transactivation domain in mouse brain. Neurosci Lett. 2009 Oct 30; 464(3):218-21. PMID: 19715742.
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Ghosh S, Thakur MK. Interaction of estrogen receptor-alpha ligand binding domain with nuclear proteins of aging mouse brain. J Neurosci Res. 2009 Aug 15; 87(11):2591-600. PMID: 19326447.
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Ghosh S, Thakur MK. Interaction of estrogen receptor-alpha transactivation domain with nuclear proteins of mouse brain: p68 RNA helicase shows age- and sex-specific change. J Neurosci Res. 2009 May 01; 87(6):1323-8. PMID: 19025768.
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Thakur MK, Ghosh S. GST-tagged mouse estrogen receptor alpha-transactivation domain fusion protein is specifically degraded during its over-expression in E. coli and purification. Mol Biol Rep. 2010 Mar; 37(3):1335-40. PMID: 19319663.
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Thakur MK, Ghosh S. Interaction of estrogen receptor alpha transactivation domain with MTA1 decreases in old mouse brain. J Mol Neurosci. 2009 Mar; 37(3):269-73. PMID: 18679832.
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Ghosh S, Thakur MK. Tissue-specific expression of receptor-interacting protein in aging mouse. Age (Dordr). 2008 Dec; 30(4):237-43. PMID: 19424847.
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Ghosh S, Thakur MK. Overproduction of mouse estrogen receptor alpha-ligand binding domain decreases bacterial growth. Mol Biol Rep. 2008 Dec; 35(4):589-94. PMID: 17786586.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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| Year | Publications |
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| 2007 | 1 | | 2008 | 2 | | 2009 | 4 | | 2011 | 1 | | 2014 | 1 | | 2018 | 1 | | 2019 | 1 | | 2020 | 1 | | 2021 | 4 | | 2023 | 4 |
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