Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Sabrina Leigh Spencer

TitleAsst Professor
InstitutionUniversity of Colorado Boulder
DepartmentChemistry & Biochemistry

    Collapse Research 
    Collapse research activities and funding
    K22CA188144     (SPENCER, SABRINA LEIGH)Sep 15, 2014 - Aug 31, 2017
    NIH/NCI
    Proliferation-quiescence control by integration of stress and mitogen signaling
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Arora M, Spencer SL. A Cell-Cycle "Safe Space" for Surviving Chemotherapy. Cell Syst. 2017 Sep 27; 5(3):161-162. PMID: 28957649.
      View in: PubMed
    2. Gookin S, Min M, Phadke H, Chung M, Moser J, Miller I, Carter D, Spencer SL. A map of protein dynamics during cell-cycle progression and cell-cycle exit. PLoS Biol. 2017 Sep; 15(9):e2003268. PMID: 28892491.
      View in: PubMed
    3. Arora M, Moser J, Phadke H, Basha AA, Spencer SL. Endogenous Replication Stress in Mother Cells Leads to Quiescence of Daughter Cells. Cell Rep. 2017 May 16; 19(7):1351-1364. PMID: 28514656.
      View in: PubMed
    4. Cappell SD, Chung M, Jaimovich A, Spencer SL, Meyer T. Irreversible APC(Cdh1) Inactivation Underlies the Point of No Return for Cell-Cycle Entry. Cell. 2016 Jun 30; 166(1):167-80. PMID: 27368103.
      View in: PubMed
    5. Overton KW, Spencer SL, Noderer WL, Meyer T, Wang CL. Basal p21 controls population heterogeneity in cycling and quiescent cell cycle states. Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41):E4386-93. PMID: 25267623; PMCID: PMC4205626.
    6. Spencer SL, Cappell SD, Tsai FC, Overton KW, Wang CL, Meyer T. The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit. Cell. 2013 Oct 10; 155(2):369-83. PMID: 24075009; PMCID: PMC4001917.
    7. Flusberg DA, Roux J, Spencer SL, Sorger PK. Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes. Mol Biol Cell. 2013 Jul; 24(14):2186-200. PMID: 23699397; PMCID: PMC3708725.
    8. Gaudet S, Spencer SL, Chen WW, Sorger PK. Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis. PLoS Comput Biol. 2012; 8(4):e1002482. PMID: 22570596; PMCID: PMC3343095.
    9. Spencer SL, Sorger PK. Measuring and modeling apoptosis in single cells. Cell. 2011 Mar 18; 144(6):926-39. PMID: 21414484; PMCID: PMC3087303.
    10. Kim KA, Spencer SL, Albeck JG, Burke JM, Sorger PK, Gaudet S, Kim DH. Systematic calibration of a cell signaling network model. BMC Bioinformatics. 2010 Apr 23; 11:202. PMID: 20416044.
      View in: PubMed
    11. Niepel M, Spencer SL, Sorger PK. Non-genetic cell-to-cell variability and the consequences for pharmacology. Curr Opin Chem Biol. 2009 Dec; 13(5-6):556-61. PMID: 19833543; PMCID: PMC2975492.
    12. Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK. Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature. 2009 May 21; 459(7245):428-32. PMID: 19363473; PMCID: PMC2858974.
    13. Pepper JW, Scott Findlay C, Kassen R, Spencer SL, Maley CC. Cancer research meets evolutionary biology. Evol Appl. 2009 Feb; 2(1):62-70. PMID: 25567847; PMCID: PMC3352411.
    14. Albeck JG, Burke JM, Spencer SL, Lauffenburger DA, Sorger PK. Modeling a snap-action, variable-delay switch controlling extrinsic cell death. PLoS Biol. 2008 Dec 02; 6(12):2831-52. PMID: 19053173.
      View in: PubMed
    15. Spencer SL, Gerety RA, Pienta KJ, Forrest S. Modeling somatic evolution in tumorigenesis. PLoS Comput Biol. 2006 Aug 18; 2(8):e108. PMID: 16933983; PMCID: PMC1550273.
    16. Spencer SL, Berryman MJ, GarcĂ­a JA, Abbott D. An ordinary differential equation model for the multistep transformation to cancer. J Theor Biol. 2004 Dec 21; 231(4):515-24. PMID: 15488528.
      View in: PubMed
    Spencer's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _

    Copyright © 2017 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.10.0)