Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Leslie Anne Leinwand

TitleDistinguished Professor
InstitutionUniversity of Colorado Boulder
DepartmentBiology-MCD Instruction
Phone303/492-7606
    Other Positions
    TitleDirector-Faculty
    InstitutionUniversity of Colorado Boulder
    DepartmentBiology-MCD Instruction


    Collapse Research 
    Collapse research activities and funding
    R01HL119937     (LEINWAND, LESLIE ANNE)Apr 1, 2014 - Sep 30, 2018
    NIH
    Translating Python Biology to the Mammalian Heart
    Role: Principal Investigator
    R01HL117138     (LEINWAND, LESLIE ANNE)Aug 20, 2013 - Jan 31, 2022
    NIH
    Molecular characterization of cardiomyopathy mutations in human cardiac myosin
    Role: Principal Investigator
    R01HL085573     (LEINWAND, LESLIE ANNE)Apr 16, 2007 - Mar 31, 2012
    NIH
    Mechanisms of myopathy caused by mutations in the myosin rod
    Role: Principal Investigator
    R25RR017253     (LEINWAND, LESLIE ANNE)Sep 30, 2002 - Aug 31, 2006
    NIH
    DENVER CARDIOVASCULAR HEALTH EDUCATION ALLIANCE, PHASE I
    Role: Principal Investigator
    R13HL069887     (LEINWAND, LESLIE ANNE)Jun 1, 2002 - May 31, 2003
    NIH
    Conference on Molecular Biology of the Heart
    Role: Principal Investigator
    R01AR048817     (LEINWAND, LESLIE ANNE)May 1, 2002 - Apr 30, 2008
    NIH
    Developmental Myosin Heavy Chain Regulation and Function
    Role: Principal Investigator
    R13AR044487     (LEINWAND, LESLIE ANNE)Apr 1, 1997 - Mar 31, 1998
    NIH
    CONFERENCE ON MOLECULAR BIOLOGY OF MUSCLE DEVELOPMENT
    Role: Principal Investigator
    T32HL007822     (BUTTRICK, PETER N.)Jul 1, 1996 - Jun 30, 2024
    NIH
    Post Graduate Studies in Cardiovascular Research
    Role: Co-Principal Investigator
    T32HL007851     (LEINWAND, LESLIE ANNE)Jul 1, 1996 - Jun 30, 2007
    NIH
    Mechanisms of Cardiovascular Disease and Gene Therapy
    Role: Principal Investigator
    R01HL050560     (LEINWAND, LESLIE ANNE)Jul 1, 1993 - Jan 31, 2013
    NIH
    Mediators of Cardiac Adaptation
    Role: Principal Investigator
    R37HL050560     (LEINWAND, LESLIE ANNE)Jul 1, 1993 - Jun 30, 2003
    NIH
    IN VIVO MODELS OF CARDIAC GENE REGULATION
    Role: Principal Investigator
    R13AR041717     (LEINWAND, LESLIE ANNE)Jun 12, 1992 - Jun 11, 1993
    NIH
    GORDON RESEARCH CONFERENCE--CELL &MOL BIO OF MYOGENESIS
    Role: Principal Investigator
    U09RG000142     (STANTON, BRUCE A.)Jul 1, 1991 - Sep 30, 2006
    NIH
    PHYSIOLOGY AND PATHOLOGY SPECIALS
    Role: Co-Principal Investigator
    T32HL007675     (SIBINGA, NICHOLAS E)Jul 1, 1989 - Jun 30, 2015
    NIH
    Mechanisms of Cardiovascular Diseases
    Role: Co-Principal Investigator
    R01GM029090     (LEINWAND, LESLIE ANNE)Sep 1, 1981 - May 31, 2028
    NIH
    Myosin Gene Diversity and Function
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Martin TG, Juarros MA, Cleveland JC, Bristow MR, Ambardekar AV, Buttrick PM, Leinwand LA. Assessment of Autophagy Markers Suggests Increased Activity Following LVAD Therapy. JACC Basic Transl Sci. 2023 Sep; 8(9):1043-1056. PMID: 37791310.
      View in: PubMed
    2. Lehman SJ, Meller A, Solieva SO, Lotthammer JM, Greenberg L, Langer SJ, Greenberg MJ, Tardiff JC, Bowman GR, Leinwand L. Divergent Molecular Phenotypes in Point Mutations at the Same Residue in Beta-Myosin Heavy Chain Lead to Distinct Cardiomyopathies. bioRxiv. 2023 Jul 03. PMID: 37461648.
      View in: PubMed
    3. Liu C, Karabina A, Meller A, Bhattacharjee A, Agostino CJ, Bowman GR, Ruppel KM, Spudich JA, Leinwand LA. Homologous mutations in ?, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation. bioRxiv. 2023 Jul 02. PMID: 37425764.
      View in: PubMed
    4. Russell AJ, DuVall M, Barthel B, Qian Y, Peter AK, Newell-Stamper BL, Hunt K, Lehman S, Madden M, Schlachter S, Robertson B, Van Deusen A, Rodriguez HM, Vera C, Su Y, Claflin DR, Brooks SV, Nghiem P, Rutledge A, Juehne TI, Yu J, Barton ER, Luo YE, Patsalos A, Nagy L, Sweeney HL, Leinwand LA, Koch K. Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy. J Clin Invest. 2023 05 15; 133(10). PMID: 36995778.
      View in: PubMed
    5. Liang Q, Chan YC, Toscano J, Bjorkman KK, Leinwand LA, Parker R, Nozik ES, Nesbitt DJ, Ye J. Breath analysis by ultra-sensitive broadband laser spectroscopy detects SARS-CoV-2 infection. J Breath Res. 2023 04 05; 17(3). PMID: 37016829.
      View in: PubMed
    6. Lee LA, Barrick SK, Buvoli AE, Walklate J, Stump WT, Geeves M, Greenberg MJ, Leinwand LA. Distinct effects of two hearing loss-associated mutations in?the sarcomeric myosin MYH7b. J Biol Chem. 2023 05; 299(5):104631. PMID: 36963494.
      View in: PubMed
    7. Meller A, Lotthammer JM, Smith LG, Novak B, Lee LA, Kuhn CC, Greenberg L, Leinwand LA, Greenberg MJ, Bowman GR. Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains. Elife. 2023 01 27; 12. PMID: 36705568.
      View in: PubMed
    8. Gotthardt M, Badillo-Lisakowski V, Parikh VN, Ashley E, Furtado M, Carmo-Fonseca M, Schudy S, Meder B, Grosch M, Steinmetz L, Crocini C, Leinwand L. Cardiac splicing as a diagnostic and therapeutic target. Nat Rev Cardiol. 2023 08; 20(8):517-530. PMID: 36653465.
      View in: PubMed
    9. Martin TG, Juarros MA, Leinwand LA. Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential. Nat Rev Cardiol. 2023 05; 20(5):347-363. PMID: 36596855.
      View in: PubMed
    10. Lee LA, Barrick SK, Meller A, Walklate J, Lotthammer JM, Tay JW, Stump WT, Bowman G, Geeves MA, Greenberg MJ, Leinwand LA. Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles. J Biol Chem. 2023 01; 299(1):102657. PMID: 36334627.
      View in: PubMed
    11. Tan Y, Martin TG, Harrison BC, Leinwand LA. Utility of the burmese Python as a model for studying plasticity of extreme physiological systems. J Muscle Res Cell Motil. 2023 Jun; 44(2):95-106. PMID: 36316565.
      View in: PubMed
    12. Molkentin JD, Leinwand LA. Remembering Jeff Robbins: The Father of Cardiac Transgenesis. JACC Basic Transl Sci. 2022 Oct; 7(10):1063-1065. PMID: 36337923.
      View in: PubMed
    13. Walker CJ, Batan D, Bishop CT, Ramirez D, Aguado BA, Schroeder ME, Crocini C, Schwisow J, Moulton K, Macdougall L, Weiss RM, Allen MA, Dowell R, Leinwand LA, Anseth KS. Extracellular matrix stiffness controls cardiac valve myofibroblast activation through epigenetic remodeling. Bioeng Transl Med. 2022 Sep; 7(3):e10394. PMID: 36176599.
      View in: PubMed
    14. Zhao Y, Riching AS, Knight WE, Chi C, Broadwell LJ, Du Y, Abdel-Hafiz M, Ambardekar AV, Irwin DC, Proenza C, Xu H, Leinwand LA, Walker LA, Woulfe KC, Bristow MR, Buttrick PM, Song K. Cardiomyocyte-Specific Long Noncoding RNA Regulates Alternative Splicing of the Triadin Gene in the Heart. Circulation. 2022 08 30; 146(9):699-714. PMID: 35862102.
      View in: PubMed
    15. Axelsson Raja A, Wakimoto H, DeLaughter DM, Reichart D, Gorham J, Conner DA, Lun M, Probst CK, Sakai N, Knipe RS, Montesi SB, Shea B, Adam LP, Leinwand LA, Wan W, Choi ES, Lindberg EL, Patone G, Noseda M, H?bner N, Seidman CE, Tager AM, Seidman JG, Ho CY. Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model. Proc Natl Acad Sci U S A. 2022 07 12; 119(28):e2204174119. PMID: 35787042.
      View in: PubMed
    16. Magida JA, Tan Y, Wall CE, Harrison BC, Marr TG, Peter AK, Riquelme CA, Leinwand LA. Burmese pythons exhibit a transient adaptation to nutrient overload that prevents liver damage. J Gen Physiol. 2022 04 04; 154(4). PMID: 35323838.
      View in: PubMed
    17. Lehman SJ, Crocini C, Leinwand LA. Targeting the sarcomere in inherited cardiomyopathies. Nat Rev Cardiol. 2022 06; 19(6):353-363. PMID: 35304599.
      View in: PubMed
    18. Muehleman DL, Crocini C, Swearingen AR, Ozeroff CD, Leinwand LA. Regression from pathological hypertrophy in mice is sexually dimorphic and stimulus specific. Am J Physiol Heart Circ Physiol. 2022 05 01; 322(5):H785-H797. PMID: 35302880.
      View in: PubMed
    19. Aguado BA, Walker CJ, Grim JC, Schroeder ME, Batan D, Vogt BJ, Rodriguez AG, Schwisow JA, Moulton KS, Weiss RM, Heistad DD, Leinwand LA, Anseth KS. Genes That Escape X Chromosome Inactivation Modulate Sex Differences in Valve Myofibroblasts. Circulation. 2022 02 15; 145(7):513-530. PMID: 35000411.
      View in: PubMed
    20. Walker CJ, Crocini C, Ramirez D, Killaars AR, Grim JC, Aguado BA, Clark K, Allen MA, Dowell RD, Leinwand LA, Anseth KS. Author Correction: Nuclear mechanosensing drives chromatin remodelling in persistently activated fibroblasts. Nat Biomed Eng. 2021 Dec; 5(12):1517-1518. PMID: 34050334.
      View in: PubMed
    21. Bjorkman KK, Saldi TK, Lasda E, Bauer LC, Kovarik J, Gonzales PK, Fink MR, Tat KL, Hager CR, Davis JC, Ozeroff CD, Brisson GR, Larremore DB, Leinwand LA, McQueen MB, Parker R. Higher Viral Load Drives Infrequent Severe Acute Respiratory Syndrome Coronavirus 2 Transmission Between Asymptomatic Residence Hall Roommates. J Infect Dis. 2021 10 28; 224(8):1316-1324. PMID: 34302469.
      View in: PubMed
    22. Reeves K, Liebig J, Feula A, Saldi T, Lasda E, Johnson W, Lilienfeld J, Maggi J, Pulley K, Wilkerson PJ, Real B, Zak G, Davis J, Fink M, Gonzales P, Hager C, Ozeroff C, Tat K, Alkire M, Butler C, Coe E, Darby J, Freeman N, Heuer H, Jones JR, Karr M, Key S, Maxwell K, Nelson L, Saldana E, Shea R, Salveson L, Tomlinson K, Vargas-Barriga J, Vigil B, Brisson G, Parker R, Leinwand LA, Bjorkman K, Mansfeldt C. High-resolution within-sewer SARS-CoV-2 surveillance facilitates informed intervention. Water Res. 2021 Oct 01; 204:117613. PMID: 34500183.
      View in: PubMed
    23. Lee LA, Broadwell LJ, Buvoli M, Leinwand LA. Nonproductive Splicing Prevents Expression of MYH7b Protein in the Mammalian Heart. J Am Heart Assoc. 2021 07 20; 10(14):e020965. PMID: 34227390.
      View in: PubMed
    24. Walker CJ, Schroeder ME, Aguado BA, Anseth KS, Leinwand LA. Matters of the heart: Cellular sex differences. J Mol Cell Cardiol. 2021 11; 160:42-55. PMID: 34166708.
      View in: PubMed
    25. Johnson CA, McGreig JE, Jeanfavre ST, Walklate J, Vera CD, Farr? M, Mulvihill DP, Baines AJ, Ridout M, Leinwand LA, Wass MN, Geeves MA. Identification of sequence changes in myosin II that adjust muscle contraction velocity. PLoS Biol. 2021 06; 19(6):e3001248. PMID: 34111116.
      View in: PubMed
    26. Yang Q, Saldi TK, Gonzales PK, Lasda E, Decker CJ, Tat KL, Fink MR, Hager CR, Davis JC, Ozeroff CD, Muhlrad D, Clark SK, Fattor WT, Meyerson NR, Paige CL, Gilchrist AR, Barbachano-Guerrero A, Worden-Sapper ER, Wu SS, Brisson GR, McQueen MB, Dowell RD, Leinwand L, Parker R, Sawyer SL. Just 2% of SARS-CoV-2-positive individuals carry 90% of the virus circulating in communities. Proc Natl Acad Sci U S A. 2021 05 25; 118(21). PMID: 33972412.
      View in: PubMed
    27. Peter AK, Walker CJ, Ceccato T, Trexler CL, Ozeroff CD, Lugo KR, Perry AR, Anseth KS, Leinwand LA. Cardiac Fibroblasts Mediate a Sexually Dimorphic Fibrotic Response to ?-Adrenergic Stimulation. J Am Heart Assoc. 2021 06; 10(11):e018876. PMID: 33998248.
      View in: PubMed
    28. Broadwell LJ, Smallegan MJ, Rigby KM, Navarro-Arriola JS, Montgomery RL, Rinn JL, Leinwand LA. Myosin 7b is a regulatory long noncoding RNA (lncMYH7b) in the human heart. J Biol Chem. 2021 Jan-Jun; 296:100694. PMID: 33895132.
      View in: PubMed
    29. Walker CJ, Crocini C, Ramirez D, Killaars AR, Grim JC, Aguado BA, Clark K, Allen MA, Dowell RD, Leinwand LA, Anseth KS. Nuclear mechanosensing drives chromatin remodelling in persistently activated fibroblasts. Nat Biomed Eng. 2021 12; 5(12):1485-1499. PMID: 33875841.
      View in: PubMed
    30. Yang Q, Meyerson NR, Clark SK, Paige CL, Fattor WT, Gilchrist AR, Barbachano-Guerrero A, Healy BG, Worden-Sapper ER, Wu SS, Muhlrad D, Decker CJ, Saldi TK, Lasda E, Gonzales P, Fink MR, Tat KL, Hager CR, Davis JC, Ozeroff CD, Brisson GR, McQueen MB, Leinwand LA, Parker R, Sawyer SL. Saliva TwoStep for rapid detection of asymptomatic SARS-CoV-2 carriers. Elife. 2021 03 29; 10. PMID: 33779548.
      View in: PubMed
    31. Yang Q, Saldi TK, Lasda E, Decker CJ, Paige CL, Muhlrad D, Gonzales PK, Fink MR, Tat KL, Hager CR, Davis JC, Ozeroff CD, Meyerson NR, Clark SK, Fattor WT, Gilchrist AR, Barbachano-Guerrero A, Worden-Sapper ER, Wu SS, Brisson GR, McQueen MB, Dowell RD, Leinwand L, Parker R, Sawyer SL. Just 2% of SARS-CoV-2-positive individuals carry 90% of the virus circulating in communities. medRxiv. 2021 Mar 05. PMID: 33688663.
      View in: PubMed
    32. Yang Q, Meyerson NR, Clark SK, Paige CL, Fattor WT, Gilchrist AR, Barbachano-Guerrero A, Healy BG, Worden-Sapper ER, Wu SS, Muhlrad D, Decker CJ, Saldi TK, Lasda E, Gonzales PK, Fink MR, Tat KL, Hager CR, Davis JC, Ozeroff CD, Brisson GR, McQueen MB, Leinwand L, Parker R, Sawyer SL. Saliva TwoStep for rapid detection of asymptomatic SARS-CoV-2 carriers. medRxiv. 2021 Feb 16. PMID: 33619503.
      View in: PubMed
    33. Lakdawala NK, Olivotto I, Day SM, Han L, Ashley EA, Michels M, Ingles J, Semsarian C, Jacoby D, Jefferies JL, Colan SD, Pereira AC, Rossano JW, Wittekind S, Ware JS, Saberi S, Helms AS, Cirino AL, Leinwand LA, Seidman CE, Ho CY. Associations Between Female Sex, Sarcomere Variants, and Clinical Outcomes in Hypertrophic Cardiomyopathy. Circ Genom Precis Med. 2021 02; 14(1):e003062. PMID: 33284039.
      View in: PubMed
    34. Ceccato TL, Starbuck RB, Hall JK, Walker CJ, Brown TE, Killgore JP, Anseth KS, Leinwand LA. Defining the Cardiac Fibroblast Secretome in a Fibrotic Microenvironment. J Am Heart Assoc. 2020 10 20; 9(19):e017025. PMID: 32924724.
      View in: PubMed
    35. Bjorkman KK, Guess MG, Harrison BC, Polmear MM, Peter AK, Leinwand LA. miR-206 enforces a slow muscle phenotype. J Cell Sci. 2020 08 11; 133(15). PMID: 32620696.
      View in: PubMed
    36. I?igo MR, Amorese AJ, Tarpey MD, Balestrieri NP, Jones KG, Patteson DJ, Jackson KC, Torres MJ, Lin CT, Smith CD, Heden TD, McMillin SL, Weyrauch LA, Stanley EC, Schmidt CA, Kilburg-Basnyat BB, Reece SW, Psaltis CE, Leinwand LA, Funai K, McClung JM, Gowdy KM, Witczak CA, Lowe DA, Neufer PD, Spangenburg EE. Estrogen receptor-a in female skeletal muscle is not required for regulation of muscle insulin sensitivity and mitochondrial regulation. Mol Metab. 2020 04; 34:1-15. PMID: 32180550.
      View in: PubMed
    37. Liu Y, Afzal J, Vakrou S, Greenland GV, Talbot CC, Hebl VB, Guan Y, Karmali R, Tardiff JC, Leinwand LA, Olgin JE, Das S, Fukunaga R, Abraham MR. Differences in microRNA-29 and Pro-fibrotic Gene Expression in Mouse and Human Hypertrophic Cardiomyopathy. Front Cardiovasc Med. 2019; 6:170. PMID: 31921893.
      View in: PubMed
    38. Bjorkman KK, Buvoli M, Pugach EK, Polmear MM, Leinwand LA. miR-1/206 downregulates splicing factor Srsf9 to promote C2C12 differentiation. Skelet Muscle. 2019 12 02; 9(1):31. PMID: 31791406.
      View in: PubMed
    39. Vera CD, Johnson CA, Walklate J, Adhikari A, Svicevic M, Mijailovich SM, Combs AC, Langer SJ, Ruppel KM, Spudich JA, Geeves MA, Leinwand LA. Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties. J Biol Chem. 2019 11 15; 294(46):17451-17462. PMID: 31582565.
      View in: PubMed
    40. Aguado BA, Schuetze KB, Grim JC, Walker CJ, Cox AC, Ceccato TL, Tan AC, Sucharov CC, Leinwand LA, Taylor MRG, McKinsey TA, Anseth KS. Transcatheter aortic valve replacements alter circulating serum factors to mediate myofibroblast deactivation. Sci Transl Med. 2019 09 11; 11(509). PMID: 31511425.
      View in: PubMed
    41. Johnson CA, Walklate J, Svicevic M, Mijailovich SM, Vera C, Karabina A, Leinwand LA, Geeves MA. The ATPase cycle of human muscle myosin II isoforms: Adaptation of a single mechanochemical cycle for different physiological roles. J Biol Chem. 2019 09 27; 294(39):14267-14278. PMID: 31387944.
      View in: PubMed
    42. Peter AK, Rossi AC, Buvoli M, Ozeroff CD, Crocini C, Perry AR, Buvoli AE, Lee LA, Leinwand LA. Expression of Normally Repressed Myosin Heavy Chain 7b in the Mammalian Heart Induces Dilated Cardiomyopathy. J Am Heart Assoc. 2019 08 06; 8(15):e013318. PMID: 31364453.
      View in: PubMed
    43. G?nay KA, Ceccato TL, Silver JS, Bannister KL, Bednarski OJ, Leinwand LA, Anseth KS. PEG-Anthracene Hydrogels as an On-Demand Stiffening Matrix To Study Mechanobiology. Angew Chem Int Ed Engl. 2019 07 15; 58(29):9912-9916. PMID: 31119851.
      View in: PubMed
    44. Crocini C, Walker CJ, Anseth KS, Leinwand LA. Three-dimensional encapsulation of adult mouse cardiomyocytes in hydrogels with tunable stiffness. Prog Biophys Mol Biol. 2020 08; 154:71-79. PMID: 31122749.
      View in: PubMed
    45. Lee LA, Karabina A, Broadwell LJ, Leinwand LA. The ancient sarcomeric myosins found in specialized muscles. Skelet Muscle. 2019 03 05; 9(1):7. PMID: 30836986.
      View in: PubMed
    46. Chung E, Haizlip KM, Leinwand LA. Pregnancy late in rodent life has detrimental effects on the heart. Am J Physiol Heart Circ Physiol. 2018 09 01; 315(3):H482-H491. PMID: 29750565.
      View in: PubMed
    47. Ujfalusi Z, Vera CD, Mijailovich SM, Svicevic M, Yu EC, Kawana M, Ruppel KM, Spudich JA, Geeves MA, Leinwand LA. Dilated cardiomyopathy myosin mutants have reduced force-generating capacity. J Biol Chem. 2018 06 08; 293(23):9017-9029. PMID: 29666183.
      View in: PubMed
    48. Vakrou S, Fukunaga R, Foster DB, Sorensen L, Liu Y, Guan Y, Woldemichael K, Pineda-Reyes R, Liu T, Tardiff JC, Leinwand LA, Tocchetti CG, Abraham TP, O'Rourke B, Aon MA, Abraham MR. Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models. JCI Insight. 2018 03 22; 3(6). PMID: 29563334.
      View in: PubMed
    49. Bristow MR, Leinwand LA, Olson EN. Entrepreneurialism in the Translational?Biologic Sciences: Why, How, and However. JACC Basic Transl Sci. 2018 Feb; 3(1):1-8. PMID: 30062188.
      View in: PubMed
    50. Trexler CL, Odell AT, Jeong MY, Dowell RD, Leinwand LA. Transcriptome and Functional Profile of Cardiac Myocytes Is Influenced by Biological Sex. Circ Cardiovasc Genet. 2017 Oct; 10(5). PMID: 29030402.
      View in: PubMed
    51. Luckey SW, Haines CD, Konhilas JP, Luczak ED, Messmer-Kratzsch A, Leinwand LA. Cyclin D2 is a critical mediator of exercise-induced cardiac hypertrophy. Exp Biol Med (Maywood). 2017 Dec; 242(18):1820-1830. PMID: 28901173.
      View in: PubMed
    52. Peter AK, Crocini C, Leinwand LA. Expanding our scientific horizons: utilization of unique model organisms in biological research. EMBO J. 2017 08 15; 36(16):2311-2314. PMID: 28694243.
      View in: PubMed
    53. Vega RB, Konhilas JP, Kelly DP, Leinwand LA. Molecular Mechanisms Underlying Cardiac Adaptation to Exercise. Cell Metab. 2017 May 02; 25(5):1012-1026. PMID: 28467921.
      View in: PubMed
    54. Wan W, Leinwand L. Computational Approach to Measuring Myocyte Disarray in Animal Models of Heart Disease. Curr Protoc Hum Genet. 2017 04 06; 93:15.11.1-15.11.9. PMID: 28384401.
      View in: PubMed
    55. Soto SM, Blake AC, Wesolowski SR, Rozance PJ, Barthel KB, Gao B, Hetrick B, McCurdy CE, Garza NG, Hay WW, Leinwand LA, Friedman JE, Brown LD. Myoblast replication is reduced in the IUGR fetus despite maintained proliferative capacity in vitro. J Endocrinol. 2017 03; 232(3):475-491. PMID: 28053000.
      View in: PubMed
    56. Schiaffino S, Murgia M, Leinwand LA, Reggiani C. Letter to the editor: Comments on Stuart et al. (2016): "Myosin content of individual human muscle fibers isolated by laser capture microdissection". Am J Physiol Cell Physiol. 2016 12 01; 311(6):C1048-C1049. PMID: 27956413.
      View in: PubMed
    57. Feinstein-Linial M, Buvoli M, Buvoli A, Sadeh M, Dabby R, Straussberg R, Shelef I, Dayan D, Leinwand LA, Birk OS. Two novel MYH7 proline substitutions cause Laing Distal Myopathy-like phenotypes with variable expressivity and neck extensor contracture. BMC Med Genet. 2016 08 12; 17(1):57. PMID: 27519903.
      View in: PubMed
    58. Peter AK, Bjerke MA, Leinwand LA. Biology of the cardiac myocyte in heart disease. Mol Biol Cell. 2016 07 15; 27(14):2149-60. PMID: 27418636.
      View in: PubMed
    59. Pugach EK, Blenck CL, Dragavon JM, Langer SJ, Leinwand LA. Estrogen receptor profiling and activity in cardiac myocytes. Mol Cell Endocrinol. 2016 08 15; 431:62-70. PMID: 27164442.
      View in: PubMed
    60. Blenck CL, Harvey PA, Reckelhoff JF, Leinwand LA. The Importance of Biological Sex and Estrogen in Rodent Models of Cardiovascular Health and Disease. Circ Res. 2016 Apr 15; 118(8):1294-312. PMID: 27081111.
      View in: PubMed
    61. Walklate J, Vera C, Bloemink MJ, Geeves MA, Leinwand L. The Most Prevalent Freeman-Sheldon Syndrome Mutations in the Embryonic Myosin Motor Share Functional Defects. J Biol Chem. 2016 May 06; 291(19):10318-31. PMID: 26945064.
      View in: PubMed
    62. Green EM, Wakimoto H, Anderson RL, Evanchik MJ, Gorham JM, Harrison BC, Henze M, Kawas R, Oslob JD, Rodriguez HM, Song Y, Wan W, Leinwand LA, Spudich JA, McDowell RS, Seidman JG, Seidman CE. A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice. Science. 2016 Feb 05; 351(6273):617-21. PMID: 26912705.
      View in: PubMed
    63. Nag S, Sommese RF, Ujfalusi Z, Combs A, Langer S, Sutton S, Leinwand LA, Geeves MA, Ruppel KM, Spudich JA. Contractility parameters of human ?-cardiac myosin with the hypertrophic cardiomyopathy mutation R403Q show loss of motor function. Sci Adv. 2015 Oct; 1(9):e1500511. PMID: 26601291.
      View in: PubMed
    64. Schiaffino S, Rossi AC, Smerdu V, Leinwand LA, Reggiani C. Developmental myosins: expression patterns and functional significance. Skelet Muscle. 2015; 5:22. PMID: 26180627.
      View in: PubMed
    65. Taylor KC, Buvoli M, Korkmaz EN, Buvoli A, Zheng Y, Heinze NT, Cui Q, Leinwand LA, Rayment I. Skip residues modulate the structural properties of the myosin rod and guide thick filament assembly. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):E3806-15. PMID: 26150528.
      View in: PubMed
    66. Pugach EK, Richmond PA, Azofeifa JG, Dowell RD, Leinwand LA. Prolonged Cre expression driven by the a-myosin heavy chain promoter can be cardiotoxic. J Mol Cell Cardiol. 2015 Sep; 86:54-61. PMID: 26141530.
      View in: PubMed
    67. Harvey PA, Leinwand LA. Oestrogen enhances cardiotoxicity induced by Sunitinib by regulation of drug transport and metabolism. Cardiovasc Res. 2015 Jul 01; 107(1):66-77. PMID: 26009590.
      View in: PubMed
    68. Hajj GP, Chu Y, Lund DD, Magida JA, Funk ND, Brooks RM, Baumbach GL, Zimmerman KA, Davis MK, El Accaoui RN, Hameed T, Doshi H, Chen B, Leinwand LA, Song LS, Heistad DD, Weiss RM. Spontaneous Aortic Regurgitation and Valvular Cardiomyopathy in Mice. Arterioscler Thromb Vasc Biol. 2015 Jul; 35(7):1653-62. PMID: 25997932.
      View in: PubMed
    69. Guess MG, Barthel KK, Harrison BC, Leinwand LA. miR-30 family microRNAs regulate myogenic differentiation and provide negative feedback on the microRNA pathway. PLoS One. 2015; 10(2):e0118229. PMID: 25689854.
      View in: PubMed
    70. Haizlip KM, Harrison BC, Leinwand LA. Sex-based differences in skeletal muscle kinetics and fiber-type composition. Physiology (Bethesda). 2015 Jan; 30(1):30-9. PMID: 25559153.
      View in: PubMed
    71. Konhilas JP, Chen H, Luczak E, McKee LA, Regan J, Watson PA, Stauffer BL, Khalpey ZI, Mckinsey TA, Horn T, LaFleur B, Leinwand LA. Diet and sex modify exercise and cardiac adaptation in the mouse. Am J Physiol Heart Circ Physiol. 2015 Jan 15; 308(2):H135-45. PMID: 25398983.
      View in: PubMed
    72. Harvey PA, Leinwand LA. Dietary phytoestrogens present in soy dramatically increase cardiotoxicity in male mice receiving a chemotherapeutic tyrosine kinase inhibitor. Mol Cell Endocrinol. 2015 Jan 05; 399:330-5. PMID: 25458703.
      View in: PubMed
    73. Wang H, Leinwand LA, Anseth KS. Cardiac valve cells and their microenvironment--insights from in vitro studies. Nat Rev Cardiol. 2014 Dec; 11(12):715-27. PMID: 25311230.
      View in: PubMed
    74. Wang H, Leinwand LA, Anseth KS. Roles of transforming growth factor-?1 and OB-cadherin in porcine cardiac valve myofibroblast differentiation. FASEB J. 2014 Oct; 28(10):4551-62. PMID: 25008089.
      View in: PubMed
    75. Burns KM, Byrne BJ, Gelb BD, K?hn B, Leinwand LA, Mital S, Pearson GD, Rodefeld M, Rossano JW, Stauffer BL, Taylor MD, Towbin JA, Redington AN. New mechanistic and therapeutic targets for pediatric heart failure: report from a National Heart, Lung, and Blood Institute working group. Circulation. 2014 Jul 01; 130(1):79-86. PMID: 24982119.
      View in: PubMed
    76. Magida JA, Leinwand LA. Metabolic crosstalk between the heart and liver impacts familial hypertrophic cardiomyopathy. EMBO Mol Med. 2014 04; 6(4):482-95. PMID: 24567073.
      View in: PubMed
    77. Chung E, Leinwand LA. Pregnancy as a cardiac stress model. Cardiovasc Res. 2014 Mar 15; 101(4):561-70. PMID: 24448313.
      View in: PubMed
    78. Harvey PA, Wall C, Luckey SW, Langer S, Leinwand LA. The python project: a unique model for extending research opportunities to undergraduate students. CBE Life Sci Educ. 2014; 13(4):698-710. PMID: 25452492.
      View in: PubMed
    79. Bloemink M, Deacon J, Langer S, Vera C, Combs A, Leinwand L, Geeves MA. The hypertrophic cardiomyopathy myosin mutation R453C alters ATP binding and hydrolysis of human cardiac ?-myosin. J Biol Chem. 2014 Feb 21; 289(8):5158-67. PMID: 24344137.
      View in: PubMed
    80. Wang H, Tibbitt MW, Langer SJ, Leinwand LA, Anseth KS. Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):19336-41. PMID: 24218588.
      View in: PubMed
    81. Chung E, Yeung F, Leinwand LA. Calcineurin activity is required for cardiac remodelling in pregnancy. Cardiovasc Res. 2013 Dec 01; 100(3):402-10. PMID: 23985902.
      View in: PubMed
    82. Bloemink MJ, Deacon JC, Resnicow DI, Leinwand LA, Geeves MA. The superfast human extraocular myosin is kinetically distinct from the fast skeletal IIa, IIb, and IId isoforms. J Biol Chem. 2013 Sep 20; 288(38):27469-27479. PMID: 23908353.
      View in: PubMed
    83. Guess MG, Barthel KK, Pugach EK, Leinwand LA. Measuring microRNA reporter activity in skeletal muscle using hydrodynamic limb vein injection of plasmid DNA combined with in vivo imaging. Skelet Muscle. 2013 Aug 01; 3(1):19. PMID: 23915674.
      View in: PubMed
    84. Wang H, Sridhar B, Leinwand LA, Anseth KS. Characterization of cell subpopulations expressing progenitor cell markers in porcine cardiac valves. PLoS One. 2013; 8(7):e69667. PMID: 23936071.
      View in: PubMed
    85. Sommese RF, Sung J, Nag S, Sutton S, Deacon JC, Choe E, Leinwand LA, Ruppel K, Spudich JA. Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human ?-cardiac myosin motor function. Proc Natl Acad Sci U S A. 2013 Jul 30; 110(31):12607-12. PMID: 23798412.
      View in: PubMed
    86. Kucherlapati R, Leinwand LA. Frank Ruddle (1929-2013). Am J Hum Genet. 2013 Jun 06; 92(6):839-40. PMID: 24242788.
      View in: PubMed
    87. Leinwand LA, Harrison BC. Young at heart. Cell. 2013 May 09; 153(4):743-5. PMID: 23663775.
      View in: PubMed
    88. Xu R, Andres-Mateos E, Mejias R, MacDonald EM, Leinwand LA, Merriman DK, Fink RH, Cohn RD. Hibernating squirrel muscle activates the endurance exercise pathway despite prolonged immobilization. Exp Neurol. 2013 Sep; 247:392-401. PMID: 23333568.
      View in: PubMed
    89. Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, Greene NP, Wu J, Estall JL, Irving BA, Lanza IR, Rasbach KA, Okutsu M, Nair KS, Yan Z, Leinwand LA, Spiegelman BM. A PGC-1a isoform induced by resistance training regulates skeletal muscle hypertrophy. Cell. 2012 Dec 07; 151(6):1319-31. PMID: 23217713.
      View in: PubMed
    90. Deacon JC, Bloemink MJ, Rezavandi H, Geeves MA, Leinwand LA. Erratum to: Identification of functional differences between recombinant human a and ? cardiac myosin motors. Cell Mol Life Sci. 2012 Dec; 69(24):4239-55. PMID: 23001010.
      View in: PubMed
    91. Andres-Mateos E, Brinkmeier H, Burks TN, Mejias R, Files DC, Steinberger M, Soleimani A, Marx R, Simmers JL, Lin B, Finanger Hedderick E, Marr TG, Lin BM, Hourd? C, Leinwand LA, Kuhl D, F?ller M, Vogelsang S, Hernandez-Diaz I, Vaughan DK, Alvarez de la Rosa D, Lang F, Cohn RD. Activation of serum/glucocorticoid-induced kinase 1 (SGK1) is important to maintain skeletal muscle homeostasis and prevent atrophy. EMBO Mol Med. 2013 01; 5(1):80-91. PMID: 23161797.
      View in: PubMed
    92. Andres-Mateos E, Mejias R, Soleimani A, Lin BM, Burks TN, Marx R, Lin B, Zellars RC, Zhang Y, Huso DL, Marr TG, Leinwand LA, Merriman DK, Cohn RD. Impaired skeletal muscle regeneration in the absence of fibrosis during hibernation in 13-lined ground squirrels. PLoS One. 2012; 7(11):e48884. PMID: 23155423.
      View in: PubMed
    93. Nandakumar J, Bell CF, Weidenfeld I, Zaug AJ, Leinwand LA, Cech TR. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature. 2012 Dec 13; 492(7428):285-9. PMID: 23103865.
      View in: PubMed
    94. Cosper PF, Harvey PA, Leinwand LA. Interferon-? causes cardiac myocyte atrophy via selective degradation of myosin heavy chain in a model of chronic myocarditis. Am J Pathol. 2012 Dec; 181(6):2038-46. PMID: 23058369.
      View in: PubMed
    95. Spangenburg EE, Geiger PC, Leinwand LA, Lowe DA. Regulation of physiological and metabolic function of muscle by female sex steroids. Med Sci Sports Exerc. 2012 Sep; 44(9):1653-62. PMID: 22525764.
      View in: PubMed
    96. Chung E, Heimiller J, Leinwand LA. Distinct cardiac transcriptional profiles defining pregnancy and exercise. PLoS One. 2012; 7(7):e42297. PMID: 22860109.
      View in: PubMed
    97. Moore JR, Leinwand L, Warshaw DM. Understanding cardiomyopathy phenotypes based on the functional impact of mutations in the myosin motor. Circ Res. 2012 Jul 20; 111(3):375-85. PMID: 22821910.
      View in: PubMed
    98. Wang H, Haeger SM, Kloxin AM, Leinwand LA, Anseth KS. Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus. PLoS One. 2012; 7(7):e39969. PMID: 22808079.
      View in: PubMed
    99. Haines CD, Harvey PA, Luczak ED, Barthel KK, Konhilas JP, Watson PA, Stauffer BL, Leinwand LA. Estrogenic compounds are not always cardioprotective and can be lethal in males with genetic heart disease. Endocrinology. 2012 Sep; 153(9):4470-9. PMID: 22778230.
      View in: PubMed
    100. Leinwand LA, Tardiff JC, Gregorio CC. Mutations in the sensitive giant titin result in a broken heart. Circ Res. 2012 Jul 06; 111(2):158-61. PMID: 22773424.
      View in: PubMed
    101. Haines CD, Harvey PA, Leinwand LA. Estrogens mediate cardiac hypertrophy in a stimulus-dependent manner. Endocrinology. 2012 Sep; 153(9):4480-90. PMID: 22759381.
      View in: PubMed
    102. Thompson RC, Buvoli M, Buvoli A, Leinwand LA. Myosin filament assembly requires a cluster of four positive residues located in the rod domain. FEBS Lett. 2012 Sep 21; 586(19):3008-12. PMID: 22728135.
      View in: PubMed
    103. Yeung F, Chung E, Guess MG, Bell ML, Leinwand LA. Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos. Nucleic Acids Res. 2012 Aug; 40(15):7303-18. PMID: 22638570.
      View in: PubMed
    104. Chung E, Yeung F, Leinwand LA. Akt and MAPK signaling mediate pregnancy-induced cardiac adaptation. J Appl Physiol (1985). 2012 May; 112(9):1564-75. PMID: 22345431.
      View in: PubMed
    105. Deacon JC, Bloemink MJ, Rezavandi H, Geeves MA, Leinwand LA. Identification of functional differences between recombinant human a and ? cardiac myosin motors. Cell Mol Life Sci. 2012 07; 69(13):2261-77. PMID: 22349210.
      View in: PubMed
    106. Buvoli M, Buvoli A, Leinwand LA. Effects of pathogenic proline mutations on myosin assembly. J Mol Biol. 2012 Feb 03; 415(5):807-18. PMID: 22155079.
      View in: PubMed
    107. Anderson WA, Amasino RM, Ares M, Banerjee U, Bartel B, Corces VG, Drennan CL, Elgin SC, Epstein IR, Fanning E, Guillette LJ, Handelsman J, Hatfull GF, Hoy RR, Kelley D, Leinwand LA, Losick R, Lu Y, Lynn DG, Neuhauser C, O'Dowd DK, Olivera T, Pevzner P, Richards-Kortum RR, Rine J, Sah RL, Strobel SA, Walker GC, Walt DR, Warner IM, Wessler S, Willard HF, Zare RN. Competencies: a cure for pre-med curriculum. Science. 2011 Nov 11; 334(6057):760-1. PMID: 22076362.
      View in: PubMed
    108. Riquelme CA, Magida JA, Harrison BC, Wall CE, Marr TG, Secor SM, Leinwand LA. Fatty acids identified in the Burmese python promote beneficial cardiac growth. Science. 2011 Oct 28; 334(6055):528-31. PMID: 22034436.
      View in: PubMed
    109. Cosper PF, Leinwand LA. Myosin heavy chain is not selectively decreased in murine cancer cachexia. Int J Cancer. 2012 Jun 01; 130(11):2722-7. PMID: 21796617.
      View in: PubMed
    110. Harvey PA, Leinwand LA. The cell biology of disease: cellular mechanisms of cardiomyopathy. J Cell Biol. 2011 Aug 08; 194(3):355-65. PMID: 21825071.
      View in: PubMed
    111. Lemon DD, Horn TR, Cavasin MA, Jeong MY, Haubold KW, Long CS, Irwin DC, McCune SA, Chung E, Leinwand LA, McKinsey TA. Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension. J Mol Cell Cardiol. 2011 Jul; 51(1):41-50. PMID: 21539845.
      View in: PubMed
    112. Luczak ED, Barthel KK, Stauffer BL, Konhilas JP, Cheung TH, Leinwand LA. Remodeling the cardiac transcriptional landscape with diet. Physiol Genomics. 2011 Jun 28; 43(12):772-80. PMID: 21487031.
      View in: PubMed
    113. Leinwand LA, Moss RL. Medicine. Chemically tuned myosin motors. Science. 2011 Mar 18; 331(6023):1392-3. PMID: 21415340.
      View in: PubMed
    114. Harrison BC, Allen DL, Leinwand LA. IIb or not IIb? Regulation of myosin heavy chain gene expression in mice and men. Skelet Muscle. 2011 Feb 01; 1(1):5. PMID: 21798083.
      View in: PubMed
    115. Cosper PF, Leinwand LA. Cancer causes cardiac atrophy and autophagy in a sexually dimorphic manner. Cancer Res. 2011 Mar 01; 71(5):1710-20. PMID: 21163868.
      View in: PubMed
    116. Wall CE, Cozza S, Riquelme CA, McCombie WR, Heimiller JK, Marr TG, Leinwand LA. Whole transcriptome analysis of the fasting and fed Burmese python heart: insights into extreme physiological cardiac adaptation. Physiol Genomics. 2011 Jan 01; 43(2):69-76. PMID: 21045117.
      View in: PubMed
    117. Konhilas JP, Boucek DM, Horn TR, Johnson GL, Leinwand LA. The role of MEKK1 in hypertrophic cardiomyopathy. Int Heart J. 2010 Jul; 51(4):277-84. PMID: 20716846.
      View in: PubMed
    118. Bell ML, Buvoli M, Leinwand LA. Uncoupling of expression of an intronic microRNA and its myosin host gene by exon skipping. Mol Cell Biol. 2010 Apr; 30(8):1937-45. PMID: 20154144.
      View in: PubMed
    119. Bhupathy P, Haines CD, Leinwand LA. Influence of sex hormones and phytoestrogens on heart disease in men and women. Womens Health (Lond). 2010 Jan; 6(1):77-95. PMID: 20088732.
      View in: PubMed
    120. Resnicow DI, Deacon JC, Warrick HM, Spudich JA, Leinwand LA. Functional diversity among a family of human skeletal muscle myosin motors. Proc Natl Acad Sci U S A. 2010 Jan 19; 107(3):1053-8. PMID: 20080549.
      View in: PubMed
    121. Armel TZ, Leinwand LA. A mutation in the beta-myosin rod associated with hypertrophic cardiomyopathy has an unexpected molecular phenotype. Biochem Biophys Res Commun. 2010 Jan 01; 391(1):352-6. PMID: 19913502.
      View in: PubMed
    122. Armel TZ, Leinwand LA. Mutations at the same amino acid in myosin that cause either skeletal or cardiac myopathy have distinct molecular phenotypes. J Mol Cell Cardiol. 2010 May; 48(5):1007-13. PMID: 19854198.
      View in: PubMed
    123. Sivaramakrishnan S, Ashley E, Leinwand L, Spudich JA. Insights into human beta-cardiac myosin function from single molecule and single cell studies. J Cardiovasc Transl Res. 2009 Dec; 2(4):426-40. PMID: 20560001.
      View in: PubMed
    124. Hughes TS, Langer SJ, Virtanen SI, Chavez RA, Watkins LR, Milligan ED, Leinwand LA. Immunogenicity of intrathecal plasmid gene delivery: cytokine release and effects on transgene expression. J Gene Med. 2009 Sep; 11(9):782-90. PMID: 19533588.
      View in: PubMed
    125. Benton JA, Kern HB, Leinwand LA, Mariner PD, Anseth KS. Statins block calcific nodule formation of valvular interstitial cells by inhibiting alpha-smooth muscle actin expression. Arterioscler Thromb Vasc Biol. 2009 Nov; 29(11):1950-7. PMID: 19679827.
      View in: PubMed
    126. Hutchinson MR, Zhang Y, Shridhar M, Evans JH, Buchanan MM, Zhao TX, Slivka PF, Coats BD, Rezvani N, Wieseler J, Hughes TS, Landgraf KE, Chan S, Fong S, Phipps S, Falke JJ, Leinwand LA, Maier SF, Yin H, Rice KC, Watkins LR. Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain Behav Immun. 2010 Jan; 24(1):83-95. PMID: 19679181.
      View in: PubMed
    127. Sloane E, Langer S, Jekich B, Mahoney J, Hughes T, Frank M, Seibert W, Huberty G, Coats B, Harrison J, Klinman D, Poole S, Maier S, Johnson K, Chavez R, Watkins LR, Leinwand L, Milligan E. Immunological priming potentiates non-viral anti-inflammatory gene therapy treatment of neuropathic pain. Gene Ther. 2009 Oct; 16(10):1210-22. PMID: 19571887.
      View in: PubMed
    128. Armel TZ, Leinwand LA. Mutations in the beta-myosin rod cause myosin storage myopathy via multiple mechanisms. Proc Natl Acad Sci U S A. 2009 Apr 14; 106(15):6291-6. PMID: 19336582.
      View in: PubMed
    129. Luckey SW, Walker LA, Smyth T, Mansoori J, Messmer-Kratzsch A, Rosenzweig A, Olson EN, Leinwand LA. The role of Akt/GSK-3beta signaling in familial hypertrophic cardiomyopathy. J Mol Cell Cardiol. 2009 May; 46(5):739-47. PMID: 19233194.
      View in: PubMed
    130. Hamady M, Buvoli M, Leinwand LA, Knight R. Estimate of the abundance of cardiomyopathic mutations in the ?-myosin gene. Int J Cardiol. 2010 Sep 24; 144(1):124-6. PMID: 19174318.
      View in: PubMed
    131. Luczak ED, Leinwand LA. Sex-based cardiac physiology. Annu Rev Physiol. 2009; 71:1-18. PMID: 18828746.
      View in: PubMed
    132. Chung E, Leinwand LA. Rescuing cardiac malfunction: the roles of the chaperone-like small heat shock proteins. Circ Res. 2008 Dec 05; 103(12):1351-3. PMID: 19059837.
      View in: PubMed
    133. Hughes TS, Langer SJ, Johnson KW, Chavez RA, Watkins LR, Milligan ED, Leinwand LA. Intrathecal injection of naked plasmid DNA provides long-term expression of secreted proteins. Mol Ther. 2009 Jan; 17(1):88-94. PMID: 18941439.
      View in: PubMed
    134. Sloane E, Ledeboer A, Seibert W, Coats B, van Strien M, Maier SF, Johnson KW, Chavez R, Watkins LR, Leinwand L, Milligan ED, Van Dam AM. Anti-inflammatory cytokine gene therapy decreases sensory and motor dysfunction in experimental Multiple Sclerosis: MOG-EAE behavioral and anatomical symptom treatment with cytokine gene therapy. Brain Behav Immun. 2009 Jan; 23(1):92-100. PMID: 18835435.
      View in: PubMed
    135. Buvoli M, Hamady M, Leinwand LA, Knight R. Bioinformatics assessment of beta-myosin mutations reveals myosin's high sensitivity to mutations. Trends Cardiovasc Med. 2008 May; 18(4):141-9. PMID: 18555187.
      View in: PubMed
    136. Resnicow DI, Hooft AM, Harrison BC, Baker JE, Leinwand LA. GFP fails to inhibit actin-myosin interactions in vitro. Nat Methods. 2008 Mar; 5(3):212-3; author reply 213-4. PMID: 18309305.
      View in: PubMed
    137. Harrison BC, Leinwand LA. Fighting fat with muscle: bulking up to slim down. Cell Metab. 2008 Feb; 7(2):97-8. PMID: 18249167.
      View in: PubMed
    138. Jensen DR, Knaub LA, Konhilas JP, Leinwand LA, MacLean PS, Eckel RH. Increased thermoregulation in cold-exposed transgenic mice overexpressing lipoprotein lipase in skeletal muscle: an avian phenotype? J Lipid Res. 2008 Apr; 49(4):870-9. PMID: 18175800.
      View in: PubMed
    139. Konhilas JP, Leinwand LA. The effects of biological sex and diet on the development of heart failure. Circulation. 2007 Dec 04; 116(23):2747-59. PMID: 18056540.
      View in: PubMed
    140. Sheren J, Langer SJ, Leinwand LA. A randomized library approach to identifying functional lox site domains for the Cre recombinase. Nucleic Acids Res. 2007; 35(16):5464-73. PMID: 17702764.
      View in: PubMed
    141. Buvoli M, Buvoli A, Leinwand LA. Interplay between exonic splicing enhancers, mRNA processing, and mRNA surveillance in the dystrophic Mdx mouse. PLoS One. 2007 May 09; 2(5):e427. PMID: 17487273.
      View in: PubMed
    142. Benoit DS, Tripodi MC, Blanchette JO, Langer SJ, Leinwand LA, Anseth KS. Integrin-linked kinase production prevents anoikis in human mesenchymal stem cells. J Biomed Mater Res A. 2007 May; 81(2):259-68. PMID: 17335036.
      View in: PubMed
    143. Watson PA, Reusch JE, McCune SA, Leinwand LA, Luckey SW, Konhilas JP, Brown DA, Chicco AJ, Sparagna GC, Long CS, Moore RL. Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H246-59. PMID: 17337597.
      View in: PubMed
    144. Leinwand LA. Molecular events underlying pregnancy-induced cardiomyopathy. Cell. 2007 Feb 09; 128(3):437-8. PMID: 17289564.
      View in: PubMed
    145. Ledeboer A, Jekich BM, Sloane EM, Mahoney JH, Langer SJ, Milligan ED, Martin D, Maier SF, Johnson KW, Leinwand LA, Chavez RA, Watkins LR. Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. Brain Behav Immun. 2007 Jul; 21(5):686-98. PMID: 17174526.
      View in: PubMed
    146. Milligan ED, Soderquist RG, Malone SM, Mahoney JH, Hughes TS, Langer SJ, Sloane EM, Maier SF, Leinwand LA, Watkins LR, Mahoney MJ. Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain. Neuron Glia Biol. 2006 Nov; 2(4):293-308. PMID: 18079973.
      View in: PubMed
    147. Voelkel NF, Quaife RA, Leinwand LA, Barst RJ, McGoon MD, Meldrum DR, Dupuis J, Long CS, Rubin LJ, Smart FW, Suzuki YJ, Gladwin M, Denholm EM, Gail DB. Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure. Circulation. 2006 Oct 24; 114(17):1883-91. PMID: 17060398.
      View in: PubMed
    148. Luckey SW, Mansoori J, Fair K, Antos CL, Olson EN, Leinwand LA. Blocking cardiac growth in hypertrophic cardiomyopathy induces cardiac dysfunction and decreased survival only in males. Am J Physiol Heart Circ Physiol. 2007 Feb; 292(2):H838-45. PMID: 17012357.
      View in: PubMed
    149. Milligan ED, Sloane EM, Langer SJ, Hughes TS, Jekich BM, Frank MG, Mahoney JH, Levkoff LH, Maier SF, Cruz PE, Flotte TR, Johnson KW, Mahoney MM, Chavez RA, Leinwand LA, Watkins LR. Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain. Pain. 2006 Dec 15; 126(1-3):294-308. PMID: 16949747.
      View in: PubMed
    150. Geurts AM, Collier LS, Geurts JL, Oseth LL, Bell ML, Mu D, Lucito R, Godbout SA, Green LE, Lowe SW, Hirsch BA, Leinwand LA, Largaespada DA. Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers. PLoS Genet. 2006 Sep 29; 2(9):e156. PMID: 17009875.
      View in: PubMed
    151. Sucharov CC, Langer S, Bristow M, Leinwand L. Shuttling of HDAC5 in H9C2 cells regulates YY1 function through CaMKIV/PKD and PP2A. Am J Physiol Cell Physiol. 2006 Nov; 291(5):C1029-37. PMID: 16822951.
      View in: PubMed
    152. Dennehey BK, Leinwand LA, Krauter KS. Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts. J Muscle Res Cell Motil. 2006; 27(8):559-75. PMID: 16819597.
      View in: PubMed
    153. Konhilas JP, Leinwand LA. Partnering up for cardiac hypertrophy. Circ Res. 2006 Apr 28; 98(8):985-7. PMID: 16645146.
      View in: PubMed
    154. Beylkin DH, Allen DL, Leinwand LA. MyoD, Myf5, and the calcineurin pathway activate the developmental myosin heavy chain genes. Dev Biol. 2006 Jun 15; 294(2):541-53. PMID: 16584724.
      View in: PubMed
    155. Sucharov CC, Mariner PD, Nunley KR, Long C, Leinwand L, Bristow MR. A beta1-adrenergic receptor CaM kinase II-dependent pathway mediates cardiac myocyte fetal gene induction. Am J Physiol Heart Circ Physiol. 2006 Sep; 291(3):H1299-308. PMID: 16501029.
      View in: PubMed
    156. Konhilas JP, Watson PA, Maass A, Boucek DM, Horn T, Stauffer BL, Luckey SW, Rosenberg P, Leinwand LA. Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy. Circ Res. 2006 Mar 03; 98(4):540-8. PMID: 16439687.
      View in: PubMed
    157. Stauffer BL, Konhilas JP, Luczak ED, Leinwand LA. Soy diet worsens heart disease in mice. J Clin Invest. 2006 Jan; 116(1):209-16. PMID: 16395406.
      View in: PubMed
    158. Cushing MC, Jaeggli MP, Masters KS, Leinwand LA, Anseth KS. Serum deprivation improves seeding and repopulation of acellular matrices with valvular interstitial cells. J Biomed Mater Res A. 2005 Oct 01; 75(1):232-41. PMID: 16088888.
      View in: PubMed
    159. Masters KS, Shah DN, Leinwand LA, Anseth KS. Crosslinked hyaluronan scaffolds as a biologically active carrier for valvular interstitial cells. Biomaterials. 2005 May; 26(15):2517-25. PMID: 15585254.
      View in: PubMed
    160. Milligan ED, Langer SJ, Sloane EM, He L, Wieseler-Frank J, O'Connor K, Martin D, Forsayeth JR, Maier SF, Johnson K, Chavez RA, Leinwand LA, Watkins LR. Controlling pathological pain by adenovirally driven spinal production of the anti-inflammatory cytokine, interleukin-10. Eur J Neurosci. 2005 Apr; 21(8):2136-48. PMID: 15869510.
      View in: PubMed
    161. Konhilas JP, Widegren U, Allen DL, Paul AC, Cleary A, Leinwand LA. Loaded wheel running and muscle adaptation in the mouse. Am J Physiol Heart Circ Physiol. 2005 Jul; 289(1):H455-65. PMID: 15734890.
      View in: PubMed
    162. Milligan ED, Sloane EM, Langer SJ, Cruz PE, Chacur M, Spataro L, Wieseler-Frank J, Hammack SE, Maier SF, Flotte TR, Forsayeth JR, Leinwand LA, Chavez R, Watkins LR. Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10. Mol Pain. 2005 Feb 25; 1:9. PMID: 15813997.
      View in: PubMed
    163. Allen DL, Weber JN, Sycuro LK, Leinwand LA. Myocyte enhancer factor-2 and serum response factor binding elements regulate fast Myosin heavy chain transcription in vivo. J Biol Chem. 2005 Apr 29; 280(17):17126-34. PMID: 15728583.
      View in: PubMed
    164. Mariner PD, Luckey SW, Long CS, Sucharov CC, Leinwand LA. Yin Yang 1 represses alpha-myosin heavy chain gene expression in pathologic cardiac hypertrophy. Biochem Biophys Res Commun. 2005 Jan 07; 326(1):79-86. PMID: 15567155.
      View in: PubMed
    165. Maass AH, Ikeda K, Oberdorf-Maass S, Maier SK, Leinwand LA. Hypertrophy, fibrosis, and sudden cardiac death in response to pathological stimuli in mice with mutations in cardiac troponin T. Circulation. 2004 Oct 12; 110(15):2102-9. PMID: 15466629.
      View in: PubMed
    166. Masters KS, Shah DN, Walker G, Leinwand LA, Anseth KS. Designing scaffolds for valvular interstitial cells: cell adhesion and function on naturally derived materials. J Biomed Mater Res A. 2004 Oct 01; 71(1):172-80. PMID: 15368267.
      View in: PubMed
    167. Sucharov CC, Helmke SM, Langer SJ, Perryman MB, Bristow M, Leinwand L. The Ku protein complex interacts with YY1, is up-regulated in human heart failure, and represses alpha myosin heavy-chain gene expression. Mol Cell Biol. 2004 Oct; 24(19):8705-15. PMID: 15367688.
      View in: PubMed
    168. Konhilas JP, Maass AH, Luckey SW, Stauffer BL, Olson EN, Leinwand LA. Sex modifies exercise and cardiac adaptation in mice. Am J Physiol Heart Circ Physiol. 2004 Dec; 287(6):H2768-76. PMID: 15319208.
      View in: PubMed
    169. Johnston IN, Milligan ED, Wieseler-Frank J, Frank MG, Zapata V, Campisi J, Langer S, Martin D, Green P, Fleshner M, Leinwand L, Maier SF, Watkins LR. A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine. J Neurosci. 2004 Aug 18; 24(33):7353-65. PMID: 15317861.
      View in: PubMed
    170. Walker GA, Masters KS, Shah DN, Anseth KS, Leinwand LA. Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease. Circ Res. 2004 Aug 06; 95(3):253-60. PMID: 15217906.
      View in: PubMed
    171. Stelzer JE, Patel JR, Olsson MC, Fitzsimons DP, Leinwand LA, Moss RL. Expression of cardiac troponin T with COOH-terminal truncation accelerates cross-bridge interaction kinetics in mouse myocardium. Am J Physiol Heart Circ Physiol. 2004 Oct; 287(4):H1756-61. PMID: 15165990.
      View in: PubMed
    172. Olsson MC, Palmer BM, Stauffer BL, Leinwand LA, Moore RL. Morphological and functional alterations in ventricular myocytes from male transgenic mice with hypertrophic cardiomyopathy. Circ Res. 2004 Feb 06; 94(2):201-7. PMID: 14670849.
      View in: PubMed
    173. Rice NA, Leinwand LA. Skeletal myosin heavy chain function in cultured lung myofibroblasts. J Cell Biol. 2003 Oct 13; 163(1):119-29. PMID: 14557251.
      View in: PubMed
    174. Leinwand LA. Hope for a broken heart? Cell. 2003 Sep 19; 114(6):658-9. PMID: 14505565.
      View in: PubMed
    175. Leinwand LA. Sex is a potent modifier of the cardiovascular system. J Clin Invest. 2003 Aug; 112(3):302-7. PMID: 12897194.
      View in: PubMed
    176. Maass AH, Leinwand LA. Mechanisms of the pathogenesis of troponin T-based familial hypertrophic cardiomyopathy. Trends Cardiovasc Med. 2003 Aug; 13(6):232-7. PMID: 12922019.
      View in: PubMed
    177. Harrison BC, Allen DL, Girten B, Stodieck LS, Kostenuik PJ, Bateman TA, Morony S, Lacey D, Leinwand LA. Skeletal muscle adaptations to microgravity exposure in the mouse. J Appl Physiol (1985). 2003 Dec; 95(6):2462-70. PMID: 12882990.
      View in: PubMed
    178. Haubold KW, Allen DL, Capetanaki Y, Leinwand LA. Loss of desmin leads to impaired voluntary wheel running and treadmill exercise performance. J Appl Physiol (1985). 2003 Oct; 95(4):1617-22. PMID: 12844497.
      View in: PubMed
    179. Maass A, Langer SJ, Oberdorf-Maass S, Bauer S, Neyses L, Leinwand LA. Rational promoter selection for gene transfer into cardiac cells. J Mol Cell Cardiol. 2003 Jul; 35(7):823-31. PMID: 12818573.
      View in: PubMed
    180. Carnes J, Jacobson M, Leinwand L, Yarus M. Stop codon suppression via inhibition of eRF1 expression. RNA. 2003 Jun; 9(6):648-53. PMID: 12756323.
      View in: PubMed
    181. Sucharov CC, Mariner P, Long C, Bristow M, Leinwand L. Yin Yang 1 is increased in human heart failure and represses the activity of the human alpha-myosin heavy chain promoter. J Biol Chem. 2003 Aug 15; 278(33):31233-9. PMID: 12754214.
      View in: PubMed
    182. Weisbart RH, Yang F, Chan G, Wakelin R, Ferreri K, Zack DJ, Harrison B, Leinwand LA, Cole GM. Cell type specific targeted intracellular delivery into muscle of a monoclonal antibody that binds myosin IIb. Mol Immunol. 2003 Mar; 39(13):783-9. PMID: 12617993.
      View in: PubMed
    183. Haubold K, Herrmann H, Langer SJ, Evans RM, Leinwand LA, Klymkowsky MW. Acute effects of desmin mutations on cytoskeletal and cellular integrity in cardiac myocytes. Cell Motil Cytoskeleton. 2003 Feb; 54(2):105-21. PMID: 12529857.
      View in: PubMed
    184. Buvoli M, Buvoli A, Leinwand LA. Suppressor tRNAs: protocols and applications for cardiac gene transfer. Methods Mol Biol. 2003; 219:115-27. PMID: 12597002.
      View in: PubMed
    185. Allen DL, Leinwand LA. Intracellular calcium and myosin isoform transitions. Calcineurin and calcium-calmodulin kinase pathways regulate preferential activation of the IIa myosin heavy chain promoter. J Biol Chem. 2002 Nov 22; 277(47):45323-30. PMID: 12235157.
      View in: PubMed
    186. Crystal RG, Bitterman PB, Mossman B, Schwarz MI, Sheppard D, Almasy L, Chapman HA, Friedman SL, King TE, Leinwand LA, Liotta L, Martin GR, Schwartz DA, Schultz GS, Wagner CR, Musson RA. Future research directions in idiopathic pulmonary fibrosis: summary of a National Heart, Lung, and Blood Institute working group. Am J Respir Crit Care Med. 2002 Jul 15; 166(2):236-46. PMID: 12119236.
      View in: PubMed
    187. Langer SJ, Ghafoori AP, Byrd M, Leinwand L. A genetic screen identifies novel non-compatible loxP sites. Nucleic Acids Res. 2002 Jul 15; 30(14):3067-77. PMID: 12136089.
      View in: PubMed
    188. Allen DL, Harrison BC, Leinwand LA. Molecular and genetic approaches to studying exercise performance and adaptation. Exerc Sport Sci Rev. 2002 Jul; 30(3):99-105. PMID: 12150574.
      View in: PubMed
    189. Lerman I, Harrison BC, Freeman K, Hewett TE, Allen DL, Robbins J, Leinwand LA. Genetic variability in forced and voluntary endurance exercise performance in seven inbred mouse strains. J Appl Physiol (1985). 2002 Jun; 92(6):2245-55. PMID: 12015333.
      View in: PubMed
    190. Buvoli M, Langer SJ, Bialik S, Leinwand LA. Potential limitations of transcription terminators used as transgene insulators in adenoviral vectors. Gene Ther. 2002 Feb; 9(3):227-31. PMID: 11859427.
      View in: PubMed
    191. Buvoli M, Leinwand LA. Direct gene transfer into mouse heart. Methods Enzymol. 2002; 346:134-42. PMID: 11883064.
      View in: PubMed
    192. Maass A, Konhilas JP, Stauffer BL, Leinwand LA. From sarcomeric mutations to heart disease: understanding familial hypertrophic cardiomyopathy. Cold Spring Harb Symp Quant Biol. 2002; 67:409-15. PMID: 12858566.
      View in: PubMed
    193. Harrison BC, Bell ML, Allen DL, Byrnes WC, Leinwand LA. Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice. J Appl Physiol (1985). 2002 Jan; 92(1):313-22. PMID: 11744674.
      View in: PubMed
    194. Allen DL, Sartorius CA, Sycuro LK, Leinwand LA. Different pathways regulate expression of the skeletal myosin heavy chain genes. J Biol Chem. 2001 Nov 23; 276(47):43524-33. PMID: 11551968.
      View in: PubMed
    195. Freeman K, Nakao K, Leinwand LA. Low sequence variation in the gene encoding the human beta-myosin heavy chain. Genomics. 2001 Aug; 76(1-3):73-80. PMID: 11549319.
      View in: PubMed
    196. Maass A, Leinwand LA. A role for calreticulin in the adult heart? J Clin Invest. 2001 May; 107(10):1223-5. PMID: 11375411.
      View in: PubMed
    197. Allen DL, Harrison BC, Maass A, Bell ML, Byrnes WC, Leinwand LA. Cardiac and skeletal muscle adaptations to voluntary wheel running in the mouse. J Appl Physiol (1985). 2001 May; 90(5):1900-8. PMID: 11299284.
      View in: PubMed
    198. Freeman K, Lerman I, Kranias EG, Bohlmeyer T, Bristow MR, Lefkowitz RJ, Iaccarino G, Koch WJ, Leinwand LA. Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy. J Clin Invest. 2001 Apr; 107(8):967-74. PMID: 11306600.
      View in: PubMed
    199. Leinwand LA. Calcineurin inhibition and cardiac hypertrophy: a matter of balance. Proc Natl Acad Sci U S A. 2001 Mar 13; 98(6):2947-9. PMID: 11248009.
      View in: PubMed
    200. S?billon P, Bonne G, Flavigny J, Venin S, Rouche A, Fiszman M, Vikstrom K, Leinwand L, Carrier L, Schwartz K. COOH-terminal truncated human cardiac MyBP-C alters myosin filament organization. C R Acad Sci III. 2001 Mar; 324(3):251-60. PMID: 11291312.
      View in: PubMed
    201. Allen DL, Harrison BC, Sartorius C, Byrnes WC, Leinwand LA. Mutation of the IIB myosin heavy chain gene results in muscle fiber loss and compensatory hypertrophy. Am J Physiol Cell Physiol. 2001 Mar; 280(3):C637-45. PMID: 11171584.
      View in: PubMed
    202. Olsson MC, Palmer BM, Leinwand LA, Moore RL. Gender and aging in a transgenic mouse model of hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol. 2001 Mar; 280(3):H1136-44. PMID: 11179057.
      View in: PubMed
    203. Chandra M, Rundell VL, Tardiff JC, Leinwand LA, De Tombe PP, Solaro RJ. Ca(2+) activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T. Am J Physiol Heart Circ Physiol. 2001 Feb; 280(2):H705-13. PMID: 11158969.
      View in: PubMed
    204. Allen DL, Leinwand LA. Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains. Dev Biol. 2001 Jan 15; 229(2):383-95. PMID: 11150240.
      View in: PubMed
    205. Freeman K, Colon-Rivera C, Olsson MC, Moore RL, Weinberger HD, Grupp IL, Vikstrom KL, Iaccarino G, Koch WJ, Leinwand LA. Progression from hypertrophic to dilated cardiomyopathy in mice that express a mutant myosin transgene. Am J Physiol Heart Circ Physiol. 2001 Jan; 280(1):H151-9. PMID: 11123229.
      View in: PubMed
    206. Walker GA, Guerrero IA, Leinwand LA. Myofibroblasts: molecular crossdressers. Curr Top Dev Biol. 2001; 51:91-107. PMID: 11236717.
      View in: PubMed
    207. Carnes J, Frolova L, Zinnen S, Drugeon G, Phillippe M, Justesen J, Haenni AL, Leinwand L, Kisselev LL, Yarus M. Suppression of eukaryotic translation termination by selected RNAs. RNA. 2000 Oct; 6(10):1468-79. PMID: 11073222.
      View in: PubMed
    208. Allen DL, Harrison BC, Leinwand LA. Inactivation of myosin heavy chain genes in the mouse: diverse and unexpected phenotypes. Microsc Res Tech. 2000 Sep 15; 50(6):492-9. PMID: 10998638.
      View in: PubMed
    209. Buvoli A, Buvoli M, Leinwand LA. Enhanced detection of tRNA isoacceptors by combinatorial oligonucleotide hybridization. RNA. 2000 Jun; 6(6):912-8. PMID: 10864048.
      View in: PubMed
    210. Testa M, Ennezat PV, Vikstrom KL, Demopoulos L, Gentilucci M, Loperfido F, Fanelli R, Kitsis RN, Leinwand LA, LeJemtel TH. Modulation of vascular endothelial gene expression by physical training in patients with chronic heart failure. Ital Heart J. 2000 Jun; 1(6):426-30. PMID: 10929744.
      View in: PubMed
    211. Buvoli M, Buvoli A, Leinwand LA. Suppression of nonsense mutations in cell culture and mice by multimerized suppressor tRNA genes. Mol Cell Biol. 2000 May; 20(9):3116-24. PMID: 10757796.
      View in: PubMed
    212. Maass A, Leinwand LA. Animal models of hypertrophic cardiomyopathy. Curr Opin Cardiol. 2000 May; 15(3):189-96. PMID: 10952427.
      View in: PubMed
    213. Miyata S, Minobe W, Bristow MR, Leinwand LA. Myosin heavy chain isoform expression in the failing and nonfailing human heart. Circ Res. 2000 Mar 03; 86(4):386-90. PMID: 10700442.
      View in: PubMed
    214. Tardiff JC, Hewett TE, Factor SM, Vikstrom KL, Robbins J, Leinwand LA. Expression of the beta (slow)-isoform of MHC in the adult mouse heart causes dominant-negative functional effects. Am J Physiol Heart Circ Physiol. 2000 Feb; 278(2):H412-9. PMID: 10666070.
      View in: PubMed
    215. Li K, Zhang J, Buvoli M, Yan XD, Leinwand L, He H. Ochre suppressor transfer RNA restored dystrophin expression in mdx mice. Life Sci. 2000; 66(5):PL 83. PMID: 10681222.
      View in: PubMed
    216. Lu BD, Allen DL, Leinwand LA, Lyons GE. Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development. Dev Biol. 1999 Dec 01; 216(1):312-26. PMID: 10588881.
      View in: PubMed
    217. Tardiff JC, Hewett TE, Palmer BM, Olsson C, Factor SM, Moore RL, Robbins J, Leinwand LA. Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy. J Clin Invest. 1999 Aug; 104(4):469-81. PMID: 10449439.
      View in: PubMed
    218. Weiss A, Schiaffino S, Leinwand LA. Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity. J Mol Biol. 1999 Jul 02; 290(1):61-75. PMID: 10388558.
      View in: PubMed
    219. Welikson RE, Buck SH, Patel JR, Moss RL, Vikstrom KL, Factor SM, Miyata S, Weinberger HD, Leinwand LA. Cardiac myosin heavy chains lacking the light chain binding domain cause hypertrophic cardiomyopathy in mice. Am J Physiol. 1999 06; 276(6):H2148-58. PMID: 10362699.
      View in: PubMed
    220. Weiss A, McDonough D, Wertman B, Acakpo-Satchivi L, Montgomery K, Kucherlapati R, Leinwand L, Krauter K. Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):2958-63. PMID: 10077619.
      View in: PubMed
    221. Roopnarine O, Leinwand LA. Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy. Biophys J. 1998 Dec; 75(6):3023-30. PMID: 9826622.
      View in: PubMed
    222. Tardiff JC, Factor SM, Tompkins BD, Hewett TE, Palmer BM, Moore RL, Schwartz S, Robbins J, Leinwand LA. A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy. J Clin Invest. 1998 Jun 15; 101(12):2800-11. PMID: 9637714.
      View in: PubMed
    223. Sartorius CA, Lu BD, Acakpo-Satchivi L, Jacobsen RP, Byrnes WC, Leinwand LA. Myosin heavy chains IIa and IId are functionally distinct in the mouse. J Cell Biol. 1998 May 18; 141(4):943-53. PMID: 9585413.
      View in: PubMed
    224. Vikstrom KL, Bohlmeyer T, Factor SM, Leinwand LA. Hypertrophy, pathology, and molecular markers of cardiac pathogenesis. Circ Res. 1998 Apr 20; 82(7):773-8. PMID: 9562436.
      View in: PubMed
    225. Mayer DC, Leinwand LA. Sarcomeric gene expression and contractility in myofibroblasts. J Cell Biol. 1997 Dec 15; 139(6):1477-84. PMID: 9396753.
      View in: PubMed
    226. Acakpo-Satchivi LJ, Edelmann W, Sartorius C, Lu BD, Wahr PA, Watkins SC, Metzger JM, Leinwand L, Kucherlapati R. Growth and muscle defects in mice lacking adult myosin heavy chain genes. J Cell Biol. 1997 Dec 01; 139(5):1219-29. PMID: 9382868.
      View in: PubMed
    227. Nakao K, Minobe W, Roden R, Bristow MR, Leinwand LA. Myosin heavy chain gene expression in human heart failure. J Clin Invest. 1997 Nov 01; 100(9):2362-70. PMID: 9410916.
      View in: PubMed
    228. von Harsdorf R, Edwards JG, Shen YT, Kudej RK, Dietz R, Leinwand LA, Nadal-Ginard B, Vatner SF. Identification of a cis-acting regulatory element conferring inducibility of the atrial natriuretic factor gene in acute pressure overload. J Clin Invest. 1997 Sep 01; 100(5):1294-304. PMID: 9276748.
      View in: PubMed
    229. Li K, Welikson RE, Vikstrom KL, Leinwand LA. Direct gene transfer into the mouse heart. J Mol Cell Cardiol. 1997 May; 29(5):1499-504. PMID: 9201634.
      View in: PubMed
    230. Siri FM, Jelicks LA, Leinwand LA, Gardin JM. Gated magnetic resonance imaging of normal and hypertrophied murine hearts. Am J Physiol. 1997 May; 272(5 Pt 2):H2394-402. PMID: 9176310.
      View in: PubMed
    231. Sohn RL, Vikstrom KL, Strauss M, Cohen C, Szent-Gyorgyi AG, Leinwand LA. A 29 residue region of the sarcomeric myosin rod is necessary for filament formation. J Mol Biol. 1997 Feb 21; 266(2):317-30. PMID: 9047366.
      View in: PubMed
    232. Cohn JN, Bristow MR, Chien KR, Colucci WS, Frazier OH, Leinwand LA, Lorell BH, Moss AJ, Sonnenblick EH, Walsh RA, Mockrin SC, Reinlib L. Report of the National Heart, Lung, and Blood Institute Special Emphasis Panel on Heart Failure Research. Circulation. 1997 Feb 18; 95(4):766-70. PMID: 9054723.
      View in: PubMed
    233. Vikstrom KL, Seiler SH, Sohn RL, Strauss M, Weiss A, Welikson RE, Leinwand LA. The vertebrate myosin heavy chain: genetics and assembly properties. Cell Struct Funct. 1997 Feb; 22(1):123-9. PMID: 9113398.
      View in: PubMed
    234. Kass-Eisler A, Leinwand LA. DNA- and adenovirus-mediated gene transfer into cardiac muscle. Methods Cell Biol. 1997; 52:423-37. PMID: 9379963.
      View in: PubMed
    235. Li K, Buvoli M, Welikson RE, Vikstrom KL, Leinwand LA. Advances in cardiovascular gene transfer. Cardiologia. 1997 Jan; 42(1):39-46. PMID: 9118153.
      View in: PubMed
    236. Li K, Zhang J, Buvoli M, Yan XD, Leinwand L, He H. Ochre suppressor transfer RNA restored dystrophin expression in mdx mice. Life Sci. 1997; 61(15):PL 205-9. PMID: 9328234.
      View in: PubMed
    237. Gardin JM, Siri F, Kitsis RN, Leinwand L. Intravascular Ultrasound Catheter Evaluation of the Left Ventricle in Mice: A Feasibility Study. Echocardiography. 1996 Nov; 13(6):609-612. PMID: 11442975.
      View in: PubMed
    238. Vikstrom KL, Factor SM, Leinwand LA. Mice expressing mutant myosin heavy chains are a model for familial hypertrophic cardiomyopathy. Mol Med. 1996 Sep; 2(5):556-67. PMID: 8898372.
      View in: PubMed
    239. Vatner SF, Berk BC, Leinwand LA, Libby P, Schwartz K, Strauss HC. A second term for the editors. Status and goals for the review process. Circ Res. 1996 Jul; 79(1):1-3. PMID: 8925556.
      View in: PubMed
    240. Gall J, Kass-Eisler A, Leinwand L, Falck-Pedersen E. Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes. J Virol. 1996 Apr; 70(4):2116-23. PMID: 8642632.
      View in: PubMed
    241. Edwards JG, Lyons GE, Micales BK, Malhotra A, Factor S, Leinwand LA. Cardiomyopathy in transgenic myf5 mice. Circ Res. 1996 Mar; 78(3):379-87. PMID: 8593696.
      View in: PubMed
    242. Kass-Eisler A, Leinwand L, Gall J, Bloom B, Falck-Pedersen E. Circumventing the immune response to adenovirus-mediated gene therapy. Gene Ther. 1996 Feb; 3(2):154-62. PMID: 8867863.
      View in: PubMed
    243. Vikstrom KL, Leinwand LA. Contractile protein mutations and heart disease. Curr Opin Cell Biol. 1996 Feb; 8(1):97-105. PMID: 8791411.
      View in: PubMed
    244. Seiler SH, Fischman DA, Leinwand LA. Modulation of myosin filament organization by C-protein family members. Mol Biol Cell. 1996 Jan; 7(1):113-27. PMID: 8741844.
      View in: PubMed
    245. Weiss A, Leinwand LA. The mammalian myosin heavy chain gene family. Annu Rev Cell Dev Biol. 1996; 12:417-39. PMID: 8970733.
      View in: PubMed
    246. Kass-Eisler A, Li K, Leinwand LA. Prospects for gene therapy with direct injection of polynucleotides. Ann N Y Acad Sci. 1995 Nov 27; 772:232-40. PMID: 8546398.
      View in: PubMed
    247. Gardin JM, Siri FM, Kitsis RN, Edwards JG, Leinwand LA. Echocardiographic assessment of left ventricular mass and systolic function in mice. Circ Res. 1995 May; 76(5):907-14. PMID: 7729009.
      View in: PubMed
    248. Liao L, Sindhwani R, Rojkind M, Factor S, Leinwand L, Diamond B. Antibody-mediated autoimmune myocarditis depends on genetically determined target organ sensitivity. J Exp Med. 1995 Mar 01; 181(3):1123-31. PMID: 7869033.
      View in: PubMed
    249. Vikstrom KL, Factor SM, Leinwand LA. A murine model for hypertrophic cardiomyopathy. Z Kardiol. 1995; 84 Suppl 4:49-54. PMID: 8585273.
      View in: PubMed
    250. Smerdu V, Karsch-Mizrachi I, Campione M, Leinwand L, Schiaffino S. Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle. Am J Physiol. 1994 Dec; 267(6 Pt 1):C1723-8. PMID: 7545970.
      View in: PubMed
    251. Kass-Eisler A, Falck-Pedersen E, Elfenbein DH, Alvira M, Buttrick PM, Leinwand LA. The impact of developmental stage, route of administration and the immune system on adenovirus-mediated gene transfer. Gene Ther. 1994 Nov; 1(6):395-402. PMID: 7584105.
      View in: PubMed
    252. Kaplan ML, Cheslow Y, Vikstrom K, Malhotra A, Geenen DL, Nakouzi A, Leinwand LA, Buttrick PM. Cardiac adaptations to chronic exercise in mice. Am J Physiol. 1994 Sep; 267(3 Pt 2):H1167-73. PMID: 8092282.
      View in: PubMed
    253. Cho M, Hughes SM, Karsch-Mizrachi I, Travis M, Leinwand LA, Blau HM. Fast myosin heavy chains expressed in secondary mammalian muscle fibers at the time of their inception. J Cell Sci. 1994 Sep; 107 ( Pt 9):2361-71. PMID: 7531198.
      View in: PubMed
    254. Sindhwani R, Ismail-Beigi F, Leinwand LA. Post-transcriptional regulation of rat alpha cardiac myosin heavy chain gene expression. J Biol Chem. 1994 Feb 04; 269(5):3272-6. PMID: 8106364.
      View in: PubMed
    255. Sweeney HL, Straceski AJ, Leinwand LA, Tikunov BA, Faust L. Heterologous expression of a cardiomyopathic myosin that is defective in its actin interaction. J Biol Chem. 1994 Jan 21; 269(3):1603-5. PMID: 8294404.
      View in: PubMed
    256. Straceski AJ, Geisterfer-Lowrance A, Seidman CE, Seidman JG, Leinwand LA. Functional analysis of myosin missense mutations in familial hypertrophic cardiomyopathy. Proc Natl Acad Sci U S A. 1994 Jan 18; 91(2):589-93. PMID: 8290568.
      View in: PubMed
    257. Buttrick PM, Kaplan M, Leinwand LA, Scheuer J. Alterations in gene expression in the rat heart after chronic pathological and physiological loads. J Mol Cell Cardiol. 1994 Jan; 26(1):61-7. PMID: 8196070.
      View in: PubMed
    258. LeBlanc-Straceski JM, Fukui Y, Sohn RL, Spudich JA, Leinwand LA. Functional analysis of a cardiac myosin rod in Dictyostelium discoideum. Cell Motil Cytoskeleton. 1994; 27(4):313-26. PMID: 8069939.
      View in: PubMed
    259. Weiss A, Mayer DC, Leinwand LA. Diversity of myosin-based motility: multiple genes and functions. Soc Gen Physiol Ser. 1994; 49:159-71. PMID: 7939894.
      View in: PubMed
    260. Kass-Eisler A, Falck-Pedersen E, Alvira M, Rivera J, Buttrick PM, Wittenberg BA, Cipriani L, Leinwand LA. Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo. Proc Natl Acad Sci U S A. 1993 Dec 15; 90(24):11498-502. PMID: 8265580.
      View in: PubMed
    261. Liao L, Sindhwani R, Leinwand L, Diamond B, Factor S. Cardiac alpha-myosin heavy chains differ in their induction of myocarditis. Identification of pathogenic epitopes. J Clin Invest. 1993 Dec; 92(6):2877-82. PMID: 7504694.
      View in: PubMed
    262. Hughes SM, Cho M, Karsch-Mizrachi I, Travis M, Silberstein L, Leinwand LA, Blau HM. Three slow myosin heavy chains sequentially expressed in developing mammalian skeletal muscle. Dev Biol. 1993 Jul; 158(1):183-99. PMID: 7687223.
      View in: PubMed
    263. Buttrick PM, Kaplan ML, Kitsis RN, Leinwand LA. Distinct behavior of cardiac myosin heavy chain gene constructs in vivo. Discordance with in vitro results. Circ Res. 1993 Jun; 72(6):1211-7. PMID: 8495550.
      View in: PubMed
    264. Vikstrom KL, Rovner AS, Saez CG, Bravo-Zehnder M, Straceski AJ, Leinwand LA. Sarcomeric myosin heavy chain expressed in nonmuscle cells forms thick filaments in the presence of substoichiometric amounts of light chains. Cell Motil Cytoskeleton. 1993; 26(3):192-204. PMID: 8293476.
      View in: PubMed
    265. Ogata I, S?ez CG, Greenwel P, Ponce Mde L, Geerts A, Leinwand LA, Rojkind M. Rat liver fat-storing cell lines express sarcomeric myosin heavy chain mRNA and protein. Cell Motil Cytoskeleton. 1993; 26(2):125-32. PMID: 8287498.
      View in: PubMed
    266. Yoon SJ, Seiler SH, Kucherlapati R, Leinwand L. Organization of the human skeletal myosin heavy chain gene cluster. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):12078-82. PMID: 1465443.
      View in: PubMed
    267. Epstein HF, Fischman DA, Bader D, Changeux JP, Buckhold K, Ordahl CP, Hoffman E, Kedes LH, Konieczny S, Leinwand LA. Myoblast therapy. Science. 1992 Aug 07; 257(5071):738. PMID: 1496388.
      View in: PubMed
    268. Nadal-Ginard B, Leinwand LA, Libby P, Schwartz K, Strauss HC, Vatner SF. Cellular and molecular biology of the cardiovascular system. Circ Res. 1992 Jul; 71(1):1-2. PMID: 1606658.
      View in: PubMed
    269. Kraft R, Kadyk L, Leinwand LA. Sequence organization of variant mouse 4.5 S RNA genes and pseudogenes. Genomics. 1992 Mar; 12(3):555-66. PMID: 1373121.
      View in: PubMed
    270. Kitsis RN, Leinwand LA. Discordance between gene regulation in vitro and in vivo. Gene Expr. 1992; 2(4):313-8. PMID: 1472867.
      View in: PubMed
    271. Feghali R, Karsch-Mizrachi I, Leinwand LA, Kohtz DS. Four sarcomeric myosin heavy chain genes are expressed by human fetal skeletal muscle cells differentiating in culture. Gene Expr. 1992; 2(1):49-58. PMID: 1617302.
      View in: PubMed
    272. Buttrick PM, Kass A, Kitsis RN, Kaplan ML, Leinwand LA. Behavior of genes directly injected into the rat heart in vivo. Circ Res. 1992 Jan; 70(1):193-8. PMID: 1309314.
      View in: PubMed
    273. Leinwand LA, Leiden JM. Gene transfer into cardiac myocytes in vivo. Trends Cardiovasc Med. 1991 Oct-Nov; 1(7):271-6. PMID: 21239293.
      View in: PubMed
    274. Kitsis RN, Buttrick PM, McNally EM, Kaplan ML, Leinwand LA. Hormonal modulation of a gene injected into rat heart in vivo. Proc Natl Acad Sci U S A. 1991 May 15; 88(10):4138-42. PMID: 2034660.
      View in: PubMed
    275. Fishman GI, Eddy RL, Shows TB, Rosenthal L, Leinwand LA. The human connexin gene family of gap junction proteins: distinct chromosomal locations but similar structures. Genomics. 1991 May; 10(1):250-6. PMID: 1646158.
      View in: PubMed
    276. Fishman GI, Moreno AP, Spray DC, Leinwand LA. Functional analysis of human cardiac gap junction channel mutants. Proc Natl Acad Sci U S A. 1991 May 01; 88(9):3525-9. PMID: 1850831.
      View in: PubMed
    277. McNally EM, Bravo-Zehnder MM, Leinwand LA. Identification of sequences necessary for the association of cardiac myosin subunits. J Cell Biol. 1991 May; 113(3):585-90. PMID: 2016338.
      View in: PubMed
    278. Fishman GI, Hertzberg EL, Spray DC, Leinwand LA. Expression of connexin43 in the developing rat heart. Circ Res. 1991 Mar; 68(3):782-7. PMID: 1660362.
      View in: PubMed
    279. Buttrick P, Malhotra A, Factor S, Greenen D, Leinwand L, Scheuer J. Effect of aging and hypertension on myosin biochemistry and gene expression in the rat heart. Circ Res. 1991 Mar; 68(3):645-52. PMID: 1835908.
      View in: PubMed
    280. Frankel S, Sohn R, Leinwand L. The use of sarkosyl in generating soluble protein after bacterial expression. Proc Natl Acad Sci U S A. 1991 Feb 15; 88(4):1192-6. PMID: 1705029.
      View in: PubMed
    281. McNally E, Sohn R, Frankel S, Leinwand L. Expression of myosin and actin in Escherichia coli. Methods Enzymol. 1991; 196:368-89. PMID: 2034131.
      View in: PubMed
    282. Goodwin EB, Leinwand LA, Szent-Gy?rgyi AG. Regulation of scallop myosin by mutant regulatory light chains. J Mol Biol. 1990 Nov 05; 216(1):85-93. PMID: 2146399.
      View in: PubMed
    283. Frankel S, Condeelis J, Leinwand L. Expression of actin in Escherichia coli. Aggregation, solubilization, and functional analysis. J Biol Chem. 1990 Oct 15; 265(29):17980-7. PMID: 2211676.
      View in: PubMed
    284. Fishman GI, Spray DC, Leinwand LA. Molecular characterization and functional expression of the human cardiac gap junction channel. J Cell Biol. 1990 Aug; 111(2):589-98. PMID: 1696265.
      View in: PubMed
    285. Karsch-Mizrachi I, Feghali R, Shows TB, Leinwand LA. Generation of a full-length human perinatal myosin heavy-chain-encoding cDNA. Gene. 1990 May 14; 89(2):289-94. PMID: 2373371.
      View in: PubMed
    286. Rovner AS, McNally EM, Leinwand LA. Complete cDNA sequence of rat atrial myosin light chain 1: patterns of expression during development and with hypertension. Nucleic Acids Res. 1990 Mar 25; 18(6):1581-6. PMID: 2326197.
      View in: PubMed
    287. Saez CG, Myers JC, Shows TB, Leinwand LA. Human nonmuscle myosin heavy chain mRNA: generation of diversity through alternative polyadenylylation. Proc Natl Acad Sci U S A. 1990 Feb; 87(3):1164-8. PMID: 1967836.
      View in: PubMed
    288. Tsika RW, Bahl JJ, Leinwand LA, Morkin E. Thyroid hormone regulates expression of a transfected human alpha-myosin heavy-chain fusion gene in fetal rat heart cells. Proc Natl Acad Sci U S A. 1990 Jan; 87(1):379-83. PMID: 2296592.
      View in: PubMed
    289. McNally EM, Kraft R, Bravo-Zehnder M, Taylor DA, Leinwand LA. Full-length rat alpha and beta cardiac myosin heavy chain sequences. Comparisons suggest a molecular basis for functional differences. J Mol Biol. 1989 Dec 05; 210(3):665-71. PMID: 2614840.
      View in: PubMed
    290. McNally EM, Gianola KM, Leinwand LA. Complete nucleotide sequence of full length cDNA for rat alpha cardiac myosin heavy chain. Nucleic Acids Res. 1989 Sep 25; 17(18):7527-8. PMID: 2798111.
      View in: PubMed
    291. Kraft R, Bravo-Zehnder M, Taylor DA, Leinwand LA. Complete nucleotide sequence of full length cDNA for rat beta cardiac myosin heavy chain. Nucleic Acids Res. 1989 Sep 25; 17(18):7529-30. PMID: 2798112.
      View in: PubMed
    292. Karsch-Mizrachi I, Travis M, Blau H, Leinwand LA. Expression and DNA sequence analysis of a human embryonic skeletal muscle myosin heavy chain gene. Nucleic Acids Res. 1989 Aug 11; 17(15):6167-79. PMID: 2771643.
      View in: PubMed
    293. Feghali R, Leinwand LA. Molecular genetic characterization of a developmentally regulated human perinatal myosin heavy chain. J Cell Biol. 1989 May; 108(5):1791-7. PMID: 2715179.
      View in: PubMed
    294. McNally EM, Buttrick PM, Leinwand LA. Ventricular myosin light chain 1 is developmentally regulated and does not change in hypertension. Nucleic Acids Res. 1989 Apr 11; 17(7):2753-67. PMID: 2717409.
      View in: PubMed
    295. Leinwand LA, Sohn R, Frankel SA, Goodwin EB, McNally EM. Bacterial expression of eukaryotic contractile proteins. Cell Motil Cytoskeleton. 1989; 14(1):3-11. PMID: 2684424.
      View in: PubMed
    296. Eghbali M, Blumenfeld OO, Seifter S, Buttrick PM, Leinwand LA, Robinson TF, Zern MA, Giambrone MA. Localization of types I, III and IV collagen mRNAs in rat heart cells by in situ hybridization. J Mol Cell Cardiol. 1989 Jan; 21(1):103-13. PMID: 2716064.
      View in: PubMed
    297. Deka N, Wong E, Matera AG, Kraft R, Leinwand LA, Schmid CW. Repetitive nucleotide sequence insertions into a novel calmodulin-related gene and its processed pseudogene. Gene. 1988 Nov 15; 71(1):123-34. PMID: 2463956.
      View in: PubMed
    298. McNally EM, Goodwin EB, Spudich JA, Leinwand LA. Coexpression and assembly of myosin heavy chain and myosin light chain in Escherichia coli. Proc Natl Acad Sci U S A. 1988 Oct; 85(19):7270-3. PMID: 3050991.
      View in: PubMed
    299. Heller DL, Gianola KM, Leinwand LA. A highly conserved mouse gene with a propensity to form pseudogenes in mammals. Mol Cell Biol. 1988 Jul; 8(7):2797-803. PMID: 3405219.
      View in: PubMed
    300. Kraft R, Tardiff J, Krauter KS, Leinwand LA. Using mini-prep plasmid DNA for sequencing double stranded templates with Sequenase. Biotechniques. 1988 Jun; 6(6):544-6, 549. PMID: 3273187.
      View in: PubMed
    301. De Lozanne A, Berlot CH, Leinwand LA, Spudich JA. Expression in Escherichia coli of a functional Dictyostelium myosin tail fragment. J Cell Biol. 1987 Dec; 105(6 Pt 2):2999-3005. PMID: 3320060.
      View in: PubMed
    302. Kraft R, Leinwand LA. Sequence of the complete P protein gene and part of the M protein gene from the histidine transport operon of Escherichia coli compared to that of Salmonella typhimurium. Nucleic Acids Res. 1987 Oct 26; 15(20):8568. PMID: 3313284.
      View in: PubMed
    303. Goodwin EB, Szent-Gyorgyi AG, Leinwand LA. Cloning and characterization of the scallop essential and regulatory myosin light chain cDNAs. J Biol Chem. 1987 Aug 15; 262(23):11052-6. PMID: 2440882.
      View in: PubMed
    304. Saez LJ, Gianola KM, McNally EM, Feghali R, Eddy R, Shows TB, Leinwand LA. Human cardiac myosin heavy chain genes and their linkage in the genome. Nucleic Acids Res. 1987 Jul 10; 15(13):5443-59. PMID: 3037493.
      View in: PubMed
    305. Warrick HM, De Lozanne A, Leinwand LA, Spudich JA. Conserved protein domains in a myosin heavy chain gene from Dictyostelium discoideum. Proc Natl Acad Sci U S A. 1986 Dec; 83(24):9433-7. PMID: 3540939.
      View in: PubMed
    306. Saez L, Leinwand LA. Characterization of diverse forms of myosin heavy chain expressed in adult human skeletal muscle. Nucleic Acids Res. 1986 Apr 11; 14(7):2951-69. PMID: 2421254.
      View in: PubMed
    307. Goodenow M, Kessler K, Leinwand L, Lilly F. Absence of trisomy 15 in chemically induced murine T-cell lymphomas. Cancer Genet Cytogenet. 1986 Jan 15; 19(3-4):205-11. PMID: 3484666.
      View in: PubMed
    308. Schwartz CE, McNally E, Leinwand L, Skolnick MH. A polymorphic human myosin heavy chain locus is linked to an anonymous single copy locus (D17S1) at 17p13. Cytogenet Cell Genet. 1986; 43(1-2):117-20. PMID: 2877813.
      View in: PubMed
    309. DeLozanne A, Lewis M, Spudich JA, Leinwand LA. Cloning and characterization of a nonmuscle myosin heavy chain cDNA. Proc Natl Acad Sci U S A. 1985 Oct; 82(20):6807-10. PMID: 3901008.
      View in: PubMed
    310. Paulson KE, Deka N, Schmid CW, Misra R, Schindler CW, Rush MG, Kadyk L, Leinwand L. A transposon-like element in human DNA. Nature. 1985 Jul 25-31; 316(6026):359-61. PMID: 2862587.
      View in: PubMed
    311. Jackson M, Heller D, Leinwand L. Transcriptional measurements of mouse repeated DNA sequences. Nucleic Acids Res. 1985 May 10; 13(9):3389-403. PMID: 4000975.
      View in: PubMed
    312. Chinsky J, Goodenow MM, Jackson M, Lilly F, Leinwand L, Childs G. Comparison of endogenous murine leukemia virus proviral organization and RNA expression in 3-methylcholanthrene-induced and spontaneous thymic lymphomas in RF and AKR mice. J Virol. 1985 Jan; 53(1):94-9. PMID: 2981367.
      View in: PubMed
    313. Sun L, Paulson KE, Schmid CW, Kadyk L, Leinwand L. Non-Alu family interspersed repeats in human DNA and their transcriptional activity. Nucleic Acids Res. 1984 Mar 26; 12(6):2669-90. PMID: 6546796.
      View in: PubMed
    314. Heller D, Jackson M, Leinwand L. Organization and expression of non-Alu family interspersed repetitive DNA sequences in the mouse genome. J Mol Biol. 1984 Mar 15; 173(4):419-36. PMID: 6708106.
      View in: PubMed
    315. Enat R, Jefferson DM, Ruiz-Opazo N, Gatmaitan Z, Leinwand LA, Reid LM. Hepatocyte proliferation in vitro: its dependence on the use of serum-free hormonally defined medium and substrata of extracellular matrix. Proc Natl Acad Sci U S A. 1984 Mar; 81(5):1411-5. PMID: 6584889.
      View in: PubMed
    316. Gatmaitan Z, Jefferson DM, Ruiz-Opazo N, Biempica L, Arias IM, Dudas G, Leinwand LA, Reid LM. Regulation of growth and differentiation of a rat hepatoma cell line by the synergistic interactions of hormones and collagenous substrata. J Cell Biol. 1983 Oct; 97(4):1179-90. PMID: 6137487.
      View in: PubMed
    317. Leinwand LA, Fournier RE, Nadal-Ginard B, Shows TB. Multigene family for sarcomeric myosin heavy chain in mouse and human DNA: localization on a single chromosome. Science. 1983 Aug 19; 221(4612):766-9. PMID: 6879174.
      View in: PubMed
    318. Leinwand LA, Saez L, McNally E, Nadal-Ginard B. Isolation and characterization of human myosin heavy chain genes. Proc Natl Acad Sci U S A. 1983 Jun; 80(12):3716-20. PMID: 6304733.
      View in: PubMed
    319. Leinwand LA, Wydro RM, Nadal-Ginard B. Small RNA molecules related to the Alu family of repetitive DNA sequences. Mol Cell Biol. 1982 Nov; 2(11):1320-30. PMID: 6186902.
      View in: PubMed
    320. Krauter K, Leinwand L, D'Eustachio P, Ruddle F, Darnell JE. Structural genes of the mouse major urinary protein are on chromosome 4. J Cell Biol. 1982 Aug; 94(2):414-7. PMID: 7107707.
      View in: PubMed
    321. Pease LR, Nathenson SG, Leinwand LA. Mapping class I gene sequences in the major histocompatibility complex. Nature. 1982 Jul 22; 298(5872):382-5. PMID: 6283386.
      View in: PubMed
    322. Haynes SR, Toomey TP, Leinwand L, Jelinek WR. The Chinese hamster Alu-equivalent sequence: a conserved highly repetitious, interspersed deoxyribonucleic acid sequence in mammals has a structure suggestive of a transposable element. Mol Cell Biol. 1981 Jul; 1(7):573-83. PMID: 9279371.
      View in: PubMed
    323. Jelinek WR, Toomey TP, Leinwand L, Duncan CH, Biro PA, Choudary PV, Weissman SM, Rubin CM, Houck CM, Deininger PL, Schmid CW. Ubiquitous, interspersed repeated sequences in mammalian genomes. Proc Natl Acad Sci U S A. 1980 Mar; 77(3):1398-402. PMID: 6246492.
      View in: PubMed
    324. Swan D, D'Eustachio P, Leinwand L, Seidman J, Keithley D, Ruddle FH. Chromosomal assignment of the mouse kappa light chain genes. Proc Natl Acad Sci U S A. 1979 Jun; 76(6):2735-9. PMID: 111241.
      View in: PubMed
    325. Kozak CA, Fournier RE, Leinwand LA, Ruddle FH. Assignment of the gene governing cellular ouabain resistance to Mus musculus chromosome 3 using human/mouse microcell hybrids. Biochem Genet. 1979 Feb; 17(1-2):23-34. PMID: 454358.
      View in: PubMed
    326. Jelinek W, Leinwand L. Low molecular weight RNAs hydrogen-bonded to nuclear and cytoplasmic poly(A)-terminated RNA from cultured Chinese hamster ovary cells. Cell. 1978 Sep; 15(1):205-14. PMID: 699042.
      View in: PubMed
    327. Ruddle NH, Conta BS, Leinwand L, Kozak C, Ruddle F, Besmer P, Baltimore D. Assignment of the receptor for ecotropic murine leukemia virus to mouse chromosome 5. J Exp Med. 1978 Aug 01; 148(2):451-65. PMID: 212501.
      View in: PubMed
    328. Leinwand L, Nichols E, Ruddle FH. Assignment of the gene for glyoxylase I to mouse chromosome 17 by somatic cell genetics. Biochem Genet. 1978 Aug; 16(7-8):659-66. PMID: 569476.
      View in: PubMed
    329. Leinwand LA, Ruddle FH. Assignment of the gene for dipeptidase 2 to Mus musculus chromosome 18 by somatic cell hybridization. Biochem Genet. 1978 Jun; 16(5-6):477-84. PMID: 736882.
      View in: PubMed
    330. Leinwand LA, Kozak CA, Ruddle FH. Assignment of the genes for triose phosphate isomerase to chromosome 6 and tripeptidase-1 to chromosome 10 in Mus musculus by somatic cell hybridization. Somatic Cell Genet. 1978 Mar; 4(2):233-40. PMID: 566475.
      View in: PubMed
    331. Leinwand L, Fournier RE, Nichols EA, Ruddle FH. Assignment of the gene for adenosine kinase to chromosome 14 in Mus musculus by somatic cell hybridization. Cytogenet Cell Genet. 1978; 21(1-2):77-85. PMID: 206412.
      View in: PubMed
    Leinwand's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    See all (1013) concept(s)
    _
    Co-Authors Expand Description
    See all (56) people
    _
    Similar People Expand Description
    See all (60) people
    _
    Same Department Expand Description
    Search Department

    Copyright © 2024 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)