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Edward N Janoff

TitleProfessor-Clinical
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone303/724-4936

    Collapse Research 
    Collapse research activities and funding
    I01CX002137     (JANI, ALKESH HARIHAR)Jul 1, 2022 - Jun 30, 2026
    NIH
    Impaired B Cell and Vaccine Responses with Advance Renal Disease
    Role: Co-Principal Investigator

    I01BX004320     (JANOFF, EDWARD N)Apr 1, 2019 - Mar 31, 2024
    NIH
    Complementary Mechanisms of Protection Against Pneumococcal Infection
    Role: Principal Investigator

    IS1BX004806     (JANOFF, EDWARD N)Jan 1, 2019 - Sep 30, 2019
    NIH
    ShEEP Request for Assuring Research Reproducibility with an Integrated Sample and Data Management System
    Role: Principal Investigator

    I01CX001464     (JANOFF, EDWARD N)Jan 1, 2017 - Dec 31, 2020
    NIH
    Impact of HIV-1 and Aging on Mucosal Vaccine Responses
    Role: Principal Investigator

    R01AI108479     (JANOFF, EDWARD N)Dec 15, 2013 - May 31, 2020
    NIH
    Mechanisms of Impaired HIV-associated B cell and Pneumococcal Vaccine responses
    Role: Principal Investigator

    R01AI097265     (LUZURIAGA, KATHERINE F)Feb 9, 2012 - Jul 31, 2017
    NIH
    HIV-1 Evolution and Functional Correlates of MTCT
    Role: Co-Principal Investigator

    R21AI092468     (JANOFF, EDWARD N)Jul 1, 2011 - Jun 30, 2013
    NIH
    Cross-serotype protection against Streptococcus pneumoniae by induction of neutra
    Role: Principal Investigator

    R01HD059527     (JANOFF, EDWARD N)Sep 15, 2009 - Jun 30, 2014
    NIH
    Mucosal Determinants of HIV Infection of Infants by Breast Milk
    Role: Principal Investigator

    R21AI083615     (JANOFF, EDWARD N)Aug 5, 2009 - Jul 31, 2011
    NIH
    Mucosal Immune Ontogeny and Intestinal Microbiota in Infants
    Role: Principal Investigator

    R21AI077069     (JANOFF, EDWARD N)Sep 21, 2007 - Aug 31, 2010
    NIH
    Mucosal Mechanisms of Control of Influenza
    Role: Principal Investigator

    R21DE015072     (JANOFF, EDWARD N)Jul 22, 2003 - Nov 30, 2005
    NIH
    Role of Tonsils in Induction of Mucosal Immune Responses
    Role: Principal Investigator

    P30AI054907     (CAMPBELL, THOMAS B)May 15, 2003 - Apr 30, 2010
    NIH
    U of Colorado Center for AIDS Research
    Role: Co-Principal Investigator

    R01HD041361     (JANOFF, EDWARD N)Feb 20, 2002 - Jan 31, 2007
    NIH
    Mucosal Defense vs Transmission of HIV by Breast Milk
    Role: Principal Investigator

    R01AI048796     (JANOFF, EDWARD N)Mar 1, 2001 - Feb 28, 2008
    NIH
    MUCOSAL DEFENSE BY IGA AGAINST S PNEUMONIAE
    Role: Principal Investigator

    R01AI042240     (JANOFF, EDWARD N)Apr 1, 1998 - Jun 30, 2003
    NIH
    INTERFERON AND HOST RESPONSE TO PNEUMOCOCCAL INFECTION
    Role: Principal Investigator

    N01DE072623     (JANOFF, EDWARD N)Sep 30, 1997 - Sep 29, 2001
    NIH/NIDCR
    DENTAL AMALGAMS, MERCURY
    Role: Principal Investigator

    N01DE072621     (JANOFF, EDWARD N)Sep 28, 1997
    NIH/NIDCR
    MUCOSAL IMMUNITY TO HIV
    Role: Principal Investigator

    R01AI039445     (JANOFF, EDWARD N)Jul 1, 1996 - Jun 30, 2000
    NIH
    PNEUMOCOCCAL INFECTION AND PROGRESSION OF HIV-1 DISEASE
    Role: Principal Investigator

    N01DE042600     (JANOFF, EDWARD N)Jun 28, 1994 - Sep 27, 1997
    NIH/NIDCR
    ORAL AND TESTINAL RESPONSE TO HIV
    Role: Principal Investigator

    R29AI031373     (JANOFF, EDWARD N)Mar 1, 1991 - Aug 31, 1996
    NIH
    IMMUNITY TO PNEUMOCOCCUS IN HIV
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Okurut S, Boulware DR, Okafor E, Rhein J, Kajumbula H, Bagaya BS, Bwanga F, Olobo JO, Manabe YC, Meya DB, Janoff EN. Divergent neuroimmune signatures in the cerebrospinal fluid predict differential gender-specific survival among patients with HIV-associated cryptococcal meningitis. Front Immunol. 2023; 14:1275443. PMID: 38152404.
      View in: PubMed
    2. Okurut S, Boulware DR, Okafor E, Rhein J, Kajumbula H, Bagaya B, Bwanga F, Olobo JO, Manabe YC, Meya DB, Janoff EN. Divergent Neuroimmune Signatures in the Cerebrospinal Fluid Predict Differential Gender-Specific Survival Among Patients With HIV-Associated Cryptococcal Meningitis. medRxiv. 2023 Aug 15. PMID: 37645984.
      View in: PubMed
    3. Zhao Q, Duck LW, Killian JT, Rosenberg AF, Mannon PJ, King RG, Denson LA, Kugathasan S, Janoff EN, Jenmalm MC, Elson CO. Crohn's patients and healthy infants share immunodominant B cell response to commensal flagellin peptide epitopes. bioRxiv. 2023 Aug 11. PMID: 37609309.
      View in: PubMed
    4. Janoff EN, Brown ST, Belitskaya-Levy I, Curtis JL, Bonomo RA, Miller EK, Goldberg AM, Zehm L, Wills A, Hutchinson C, Dumont LJ, Gleason T, Shih MC. Design of VA CoronavirUs Research and Efficacy Studies-1 (VA CURES-1): A double-blind, randomized placebo-controlled trial of COVID-19 convalescent plasma in hospitalized patients with early respiratory compromise. Contemp Clin Trials Commun. 2023 Oct; 35:101190. PMID: 37560085.
      View in: PubMed
    5. Janoff EN, Tseng HF, Nguyen JL, Alfred T, Vietri J, McDaniel A, Chilson E, Yan Q, Malhotra D, Isturiz RE, Levin MJ. Incidence and clinical outcomes of pneumonia in persons with down syndrome in the United States. Vaccine. 2023 07 12; 41(31):4571-4578. PMID: 37328350.
      View in: PubMed
    6. Jones ST, Guo K, Cooper EH, Dillon SM, Wood C, Nguyen DH, Shen G, Barrett BS, Frank DN, Kroehl M, Janoff EN, Kechris K, Wilson CC, Santiago ML. Altered Immunoglobulin Repertoire and Decreased IgA Somatic Hypermutation in the Gut during Chronic HIV-1 Infection. J Virol. 2022 09 14; 96(17):e0097622. PMID: 35938870.
      View in: PubMed
    7. Bai X, Buckle AM, Vladar EK, Janoff EN, Khare R, Ordway D, Beckham D, Fornis LB, Majluf-Cruz A, Fugit RV, Freed BM, Kim S, Sandhaus RA, Chan ED. Author Correction: Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19. Sci Rep. 2022 Apr 19; 12(1):6466. PMID: 35440617.
      View in: PubMed
    8. Bai X, Buckle AM, Vladar EK, Janoff EN, Khare R, Ordway D, Beckham D, Fornis LB, Majluf-Cruz A, Fugit RV, Freed BM, Kim S, Sandhaus RA, Chan ED. Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19. Sci Rep. 2022 03 25; 12(1):5207. PMID: 35338216.
      View in: PubMed
    9. Miller EK, Goldberg AM, Janoff EN, Brown ST, Curtis JL, Bonomo RA, Shih MC, Gleason TC. Designing and implementing methodology for double-blind, placebo-controlled clinical trials using blood products within the Department of Veterans Affairs. Clin Trials. 2022 04; 19(2):137-145. PMID: 35229691.
      View in: PubMed
    10. Horn KJ, Jaberi Vivar AC, Arenas V, Andani S, Janoff EN, Clark SE. Corynebacterium Species Inhibit Streptococcus pneumoniae Colonization and Infection of the Mouse Airway. Front Microbiol. 2021; 12:804935. PMID: 35082772.
      View in: PubMed
    11. Jha V, Nicholson LK, Gardner EM, Rahkola JT, Pratap H, Scott J, Borgeson M, Jacobelli J, Janoff EN. Impact of HIV-1 Infection and Antigen Class on T Follicular Helper Cell Responses to Pneumococcal Polysaccharide-Protein Conjugate Vaccine-13. J Immunol. 2021 05 15; 206(10):2402-2411. PMID: 33931485.
      View in: PubMed
    12. Erlandson KM, Wilson MP, MaWhinney S, Rapaport E, Liu J, Wilson CC, Rahkola JT, Janoff EN, Brown TT, Campbell TB, Jankowski CM. The Impact of Moderate or High-Intensity Combined Exercise on Systemic Inflammation Among Older Persons With and Without HIV. J Infect Dis. 2021 04 08; 223(7):1161-1170. PMID: 32779711.
      View in: PubMed
    13. Wang Z, Rahkola J, Redzic JS, Chi YC, Tran N, Holyoak T, Zheng H, Janoff E, Eisenmesser E. Mechanism and inhibition of Streptococcus pneumoniae IgA1 protease. Nat Commun. 2020 11 27; 11(1):6063. PMID: 33247098.
      View in: PubMed
    14. Okurut S, Meya DB, Bwanga F, Olobo J, Eller MA, Cham-Jallow F, Bohjanen PR, Pratap H, Palmer BE, Hullsiek KH, Manabe YC, Boulware DR, Janoff EN. B Cell Compartmentalization in Blood and Cerebrospinal Fluid of HIV-Infected Ugandans with Cryptococcal Meningitis. Infect Immun. 2020 02 20; 88(3). PMID: 31871098.
      View in: PubMed
    15. Paukovich N, Redzic JS, Chi YC, Rahkola JT, Issaian A, Blue A, Hansen KC, Janoff EN, Eisenmesser EZ. Streptococcus pneumoniae G5 domains bind different ligands. Protein Sci. 2019 10; 28(10):1797-1805. PMID: 31390088.
      View in: PubMed
    16. Meya DB, Okurut S, Zziwa G, Cose S, Boulware DR, Janoff EN. HIV-Associated Cryptococcal Immune Reconstitution Inflammatory Syndrome Is Associated with Aberrant T Cell Function and Increased Cytokine Responses. J Fungi (Basel). 2019 May 23; 5(2). PMID: 31126019.
      View in: PubMed
    17. Jha V, Janoff EN. Complementary Role of CD4+ T Cells in Response to Pneumococcal Polysaccharide Vaccines in Humans. Vaccines (Basel). 2019 Feb 11; 7(1). PMID: 30754689.
      View in: PubMed
    18. Nicholson LK, Pratap H, Bowers E, Gunzburger E, Bandi SR, Gardner EM, Palmer BE, Wright T, Kittelson J, Janoff EN. Effective B cell activation in vitro during viremic HIV-1 infection with surrogate T cell stimulation. Immunobiology. 2018 12; 223(12):839-849. PMID: 30219203.
      View in: PubMed
    19. Mueller SW, Baumgartner LJ, MacLaren R, Neumann R, Wiktor AJ, Kiser TH, Lindberg G, Cava L, Fish DN, Janoff EN. Divergent humoral responses to 23-valent pneumococcal polysaccharide vaccine in critically-ill burn and neurosurgical patients. PLoS One. 2018; 13(5):e0197037. PMID: 29758059.
      View in: PubMed
    20. Sokoya M, Ramakrishnan VR, Frank DN, Rahkola J, Getz A, Kingdom TT, Kofonow JM, Nguyen Q, Janoff EN. Expression of immunoglobulin D is increased in chronic rhinosinusitis. Ann Allergy Asthma Immunol. 2017 10; 119(4):317-323.e1. PMID: 28958373.
      View in: PubMed
    21. Meya DB, Okurut S, Zziwa G, Cose S, Bohjanen PR, Mayanja-Kizza H, Joloba M, Boulware DR, Yukari Manabe C, Wahl S, Janoff EN. Monocyte Phenotype and IFN-?-Inducible Cytokine Responses Are Associated with Cryptococcal Immune Reconstitution Inflammatory Syndrome. J Fungi (Basel). 2017 Jun 02; 3(2). PMID: 29371546.
      View in: PubMed
    22. Iroh Tam PY, Thielen BK, Obaro SK, Brearley AM, Kaizer AM, Chu H, Janoff EN. Childhood pneumococcal disease in Africa - A systematic review and meta-analysis of incidence, serotype distribution, and antimicrobial susceptibility. Vaccine. 2017 04 04; 35(15):1817-1827. PMID: 28284682.
      View in: PubMed
    23. Chi YC, Rahkola JT, Kendrick AA, Holliday MJ, Paukovich N, Roberts TS, Janoff EN, Eisenmesser EZ. Streptococcus pneumoniae IgA1 protease: A metalloprotease that can catalyze in a split manner in vitro. Protein Sci. 2017 03; 26(3):600-610. PMID: 28028839.
      View in: PubMed
    24. McFarland EJ, Powell TM, Onyango-Makumbi C, Zhang W, Melander K, Naluyima P, Okurut S, Eller MA, Fowler MG, Janoff EN. Ontogeny of CD4+ T Lymphocytes With Phenotypic Susceptibility to HIV-1 During Exclusive and Nonexclusive Breastfeeding in HIV-1-Exposed Ugandan Infants. J Infect Dis. 2017 02 01; 215(3):368-377. PMID: 27932619.
      View in: PubMed
    25. Hawkins KL, Janoff EN, Janson RW. Resolution of Q Fever-Associated Cryoglobulinemia With Anti-CD20 Monoclonal Antibody Treatment. J Investig Med High Impact Case Rep. 2017 Jan-Mar; 5(1):2324709616686612. PMID: 28203574.
      View in: PubMed
    26. Janoff EN. WITHDRAWN: The microbiome and human disease pathogenesis: how do you do what you do to me ?? Transl Res. 2016 Oct 19. PMID: 27832937.
      View in: PubMed
    27. Janoff EN. The microbiome and human disease pathogenesis: how do you do what you do to me ?? Transl Res. 2017 01; 179:1-6. PMID: 27832935.
      View in: PubMed
    28. Malarkey CS, Gustafson CE, Saifee JF, Torres RM, Churchill ME, Janoff EN. Mechanism of Mitochondrial Transcription Factor A Attenuation of CpG-Induced Antibody Production. PLoS One. 2016; 11(6):e0157157. PMID: 27280778.
      View in: PubMed
    29. Meya DB, Manabe YC, Boulware DR, Janoff EN. The immunopathogenesis of cryptococcal immune reconstitution inflammatory syndrome: understanding a conundrum. Curr Opin Infect Dis. 2016 Feb; 29(1):10-22. PMID: 26658650.
      View in: PubMed
    30. Shen R, Achenbach J, Shen Y, Palaia J, Rahkola JT, Nick HJ, Smythies LE, McConnell M, Fowler MG, Smith PD, Janoff EN. Mother-to-Child HIV-1 Transmission Events Are Differentially Impacted by Breast Milk and Its Components from HIV-1-Infected Women. PLoS One. 2015; 10(12):e0145150. PMID: 26680219.
      View in: PubMed
    31. Signoracci GM, Stearns-Yoder KA, Holliman BD, Huggins JA, Janoff EN, Brenner LA. Listening to Our Patients: Learning About Suicide Risk and Protective Factors From Veterans With HIV/AIDS. J Holist Nurs. 2016 Dec; 34(4):318-328. PMID: 26578552.
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    32. Lynch AM, Wagner BD, Deterding RR, Giclas PC, Gibbs RS, Janoff EN, Holers VM, Santoro NF. The relationship of circulating proteins in early pregnancy with preterm birth. Am J Obstet Gynecol. 2016 Apr; 214(4):517.e1-517.e8. PMID: 26576488.
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    33. Bessesen MT, Kotter CV, Wagner BD, Adams JC, Kingery S, Benoit JB, Robertson CE, Janoff EN, Frank DN. MRSA colonization and the nasal microbiome in adults at high risk of colonization and infection. J Infect. 2015 Dec; 71(6):649-57. PMID: 26335708.
      View in: PubMed
    34. Meya DB, Okurut S, Zziwa G, Rolfes MA, Kelsey M, Cose S, Joloba M, Naluyima P, Palmer BE, Kambugu A, Mayanja-Kizza H, Bohjanen PR, Eller MA, Wahl SM, Boulware DR, Manabe YC, Janoff EN. Cellular immune activation in cerebrospinal fluid from ugandans with cryptococcal meningitis and immune reconstitution inflammatory syndrome. J Infect Dis. 2015 May 15; 211(10):1597-606. PMID: 25492918.
      View in: PubMed
    35. Gaensbauer JT, Rakhola JT, Onyango-Makumbi C, Mubiru M, Westcott JE, Krebs NF, Asturias EJ, Fowler MG, McFarland E, Janoff EN. Impaired haemophilus influenzae type b transplacental antibody transmission and declining antibody avidity through the first year of life represent potential vulnerabilities for HIV-exposed but -uninfected infants. Clin Vaccine Immunol. 2014 Dec; 21(12):1661-7. PMID: 25298109.
      View in: PubMed
    36. Boulware DR, Meya DB, Muzoora C, Rolfes MA, Huppler Hullsiek K, Musubire A, Taseera K, Nabeta HW, Schutz C, Williams DA, Rajasingham R, Rhein J, Thienemann F, Lo MW, Nielsen K, Bergemann TL, Kambugu A, Manabe YC, Janoff EN, Bohjanen PR, Meintjes G. Timing of antiretroviral therapy after diagnosis of cryptococcal meningitis. N Engl J Med. 2014 Jun 26; 370(26):2487-98. PMID: 24963568.
      View in: PubMed
    37. Roche AM, Richard AL, Rahkola JT, Janoff EN, Weiser JN. Antibody blocks acquisition of bacterial colonization through agglutination. Mucosal Immunol. 2015 Jan; 8(1):176-85. PMID: 24962092.
      View in: PubMed
    38. Brown GD, Meintjes G, Kolls JK, Gray C, Horsnell W, Achan B, Alber G, Aloisi M, Armstrong-James D, Beale M, Bicanic T, Black J, Bohjanen P, Botes A, Boulware DR, Brown G, Bunjun R, Carr W, Casadevall A, Chang C, Chivero E, Corcoran C, Cross A, Dawood H, Day J, De Bernardis F, De Jager V, De Repentigny L, Denning D, Eschke M, Finkelman M, Govender N, Gow N, Graham L, Gryschek R, Hammond-Aryee K, Harrison T, Heard N, Hill M, Hoving JC, Janoff E, Jarvis J, Kayuni S, King K, Kolls J, Kullberg BJ, Lalloo DG, Letang E, Levitz S, Limper A, Longley N, Machiridza TR, Mahabeer Y, Martinsons N, Meiring S, Meya D, Miller R, Molloy S, Morris L, Mukaremera L, Musubire AK, Muzoora C, Nair A, Nakiwala Kimbowa J, Netea M, Nielsen K, O'hern J, Okurut S, Parker A, Patterson T, Pennap G, Perfect J, Prinsloo C, Rhein J, Rolfes MA, Samuel C, Schutz C, Scriven J, Sebolai OM, Sojane K, Sriruttan C, Stead D, Steyn A, Thawer NK, Thienemann F, Von Hohenberg M, Vreulink JM, Wessels J, Wood K, Yang YL. AIDS-related mycoses: the way forward. Trends Microbiol. 2014 Mar; 22(3):107-9. PMID: 24581941.
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    39. Bowers E, Scamurra RW, Asrani A, Beniguel L, MaWhinney S, Keays KM, Thurn JR, Janoff EN. Decreased mutation frequencies among immunoglobulin G variable region genes during viremic HIV-1 infection. PLoS One. 2014; 9(1):e81913. PMID: 24409278.
      View in: PubMed
    40. Palaia JM, McConnell M, Achenbach JE, Gustafson CE, Stoermer KA, Nolan M, Guay LA, Leitner TK, Matovu F, Taylor AW, Fowler MG, Janoff EN. Neutralization of HIV subtypes A and D by breast milk IgG from women with HIV infection in Uganda. J Infect. 2014 Mar; 68(3):264-72. PMID: 24239588.
      View in: PubMed
    41. Gustafson CE, Higbee D, Yeckes AR, Wilson CC, De Zoeten EF, Jedlicka P, Janoff EN. Limited expression of APRIL and its receptors prior to intestinal IgA plasma cell development during human infancy. Mucosal Immunol. 2014 May; 7(3):467-77. PMID: 24045575.
      View in: PubMed
    42. Janoff EN, Rubins JB, Fasching C, Charboneau D, Rahkola JT, Plaut AG, Weiser JN. Pneumococcal IgA1 protease subverts specific protection by human IgA1. Mucosal Immunol. 2014 Mar; 7(2):249-56. PMID: 23820749.
      View in: PubMed
    43. Pujanauski LM, Janoff EN, McCarter MD, Pelanda R, Torres RM. Mouse marginal zone B cells harbor specificities similar to human broadly neutralizing HIV antibodies. Proc Natl Acad Sci U S A. 2013 Jan 22; 110(4):1422-7. PMID: 23288906.
      View in: PubMed
    44. Aizire J, McConnell MS, Mudiope P, Mubiru M, Matovu F, Parsons TL, Elbireer A, Nolan M, Janoff EN, Fowler MG. Kinetics of nevirapine and its impact on HIV-1 RNA levels in maternal plasma and breast milk over time after perinatal single-dose nevirapine. J Acquir Immune Defic Syndr. 2012 Aug 15; 60(5):483-8. PMID: 22217678.
      View in: PubMed
    45. Frank DN, Manigart O, Leroy V, Meda N, Val?a D, Zhang W, Dabis F, Pace NR, Van de Perre P, Janoff EN. Altered vaginal microbiota are associated with perinatal mother-to-child transmission of HIV in African women from Burkina Faso. J Acquir Immune Defic Syndr. 2012 Jul 01; 60(3):299-306. PMID: 22343176.
      View in: PubMed
    46. Neville MC, Anderson SM, McManaman JL, Badger TM, Bunik M, Contractor N, Crume T, Dabelea D, Donovan SM, Forman N, Frank DN, Friedman JE, German JB, Goldman A, Hadsell D, Hambidge M, Hinde K, Horseman ND, Hovey RC, Janoff E, Krebs NF, Lebrilla CB, Lemay DG, MacLean PS, Meier P, Morrow AL, Neu J, Nommsen-Rivers LA, Raiten DJ, Rijnkels M, Seewaldt V, Shur BD, VanHouten J, Williamson P. Lactation and neonatal nutrition: defining and refining the critical questions. J Mammary Gland Biol Neoplasia. 2012 Jun; 17(2):167-88. PMID: 22752723.
      View in: PubMed
    47. Janoff EN, Gustafson C, Frank DN. The world within: living with our microbial guests and guides. Transl Res. 2012 Oct; 160(4):239-45. PMID: 22732305.
      View in: PubMed
    48. Wahl SM, Redford M, Christensen S, Mack W, Cohn J, Janoff EN, Mestecky J, Jenson HB, Navazesh M, Cohen M, Reichelderfer P, Kovacs A. Systemic and mucosal differences in HIV burden, immune, and therapeutic responses. J Acquir Immune Defic Syndr. 2011 Apr 15; 56(5):401-11. PMID: 21239996.
      View in: PubMed
    49. Boulware DR, Meya DB, Bergemann TL, Wiesner DL, Rhein J, Musubire A, Lee SJ, Kambugu A, Janoff EN, Bohjanen PR. Clinical features and serum biomarkers in HIV immune reconstitution inflammatory syndrome after cryptococcal meningitis: a prospective cohort study. PLoS Med. 2010 Dec 21; 7(12):e1000384. PMID: 21253011.
      View in: PubMed
    50. Bryan CL, Beard KS, Pott GB, Rahkola J, Gardner EM, Janoff EN, Shapiro L. HIV infection is associated with reduced serum alpha-1-antitrypsin concentrations. Clin Invest Med. 2010 Dec 01; 33(6):E384-9. PMID: 21134340.
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    51. Boulware DR, Meya DB, Bergemann TL, Williams D, Vlasova-St Louis IA, Rhein J, Staddon J, Kambugu A, Janoff EN, Bohjanen PR. Antiretroviral therapy down-regulates innate antiviral response genes in patients with AIDS in sub-saharan Africa. J Acquir Immune Defic Syndr. 2010 Dec; 55(4):428-38. PMID: 20838227.
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    52. Crum-Cianflone NF, Huppler Hullsiek K, Roediger M, Ganesan A, Patel S, Landrum ML, Weintrob A, Agan BK, Medina S, Rahkola J, Hale BR, Janoff EN. A randomized clinical trial comparing revaccination with pneumococcal conjugate vaccine to polysaccharide vaccine among HIV-infected adults. J Infect Dis. 2010 Oct 01; 202(7):1114-25. PMID: 20795819.
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    53. Crum-Cianflone NF, Roediger M, Huppler Hullsiek K, Ganesan A, Landrum M, Weintrob A, Agan B, Medina S, Rahkola J, Hale B, Janoff EN. The association of ethnicity with antibody responses to pneumococcal vaccination among adults with HIV infection. Vaccine. 2010 Nov 10; 28(48):7583-8. PMID: 20887830.
      View in: PubMed
    54. Boulware DR, Bonham SC, Meya DB, Wiesner DL, Park GS, Kambugu A, Janoff EN, Bohjanen PR. Paucity of initial cerebrospinal fluid inflammation in cryptococcal meningitis is associated with subsequent immune reconstitution inflammatory syndrome. J Infect Dis. 2010 Sep 15; 202(6):962-70. PMID: 20677939.
      View in: PubMed
    55. Frank DN, Feazel LM, Bessesen MT, Price CS, Janoff EN, Pace NR. The human nasal microbiota and Staphylococcus aureus carriage. PLoS One. 2010 May 17; 5(5):e10598. PMID: 20498722.
      View in: PubMed
    56. High KP, D'Aquila RT, Fuldner RA, Gerding DN, Halter JB, Haynes L, Hazzard WR, Jackson LA, Janoff E, Levin MJ, Nayfield SG, Nichol KL, Prabhudas M, Talbot HK, Clayton CP, Henderson R, Scott CM, Tarver ED, Woolard NF, Schmader KE. Workshop on immunizations in older adults: identifying future research agendas. J Am Geriatr Soc. 2010 Apr; 58(4):765-76. PMID: 20398161.
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    57. Janoff EN, Frank DN. Pathogen-specific antibodies: codependent no longer. J Clin Invest. 2010 Apr; 120(4):1039-42. PMID: 20335652.
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    58. Hammitt LL, Bartlett JP, Li S, Rahkola J, Lang N, Janoff EN, Levin MJ, Weinberg A. Kinetics of viral shedding and immune responses in adults following administration of cold-adapted influenza vaccine. Vaccine. 2009 Dec 09; 27(52):7359-66. PMID: 19800447.
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    59. Kunisaki KM, Janoff EN. Influenza in immunosuppressed populations: a review of infection frequency, morbidity, mortality, and vaccine responses. Lancet Infect Dis. 2009 Aug; 9(8):493-504. PMID: 19628174.
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    60. Jackson LA, Janoff EN. Pneumococcal vaccination of elderly adults: new paradigms for protection. Clin Infect Dis. 2008 Nov 15; 47(10):1328-38. PMID: 18844484.
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    61. Effros RB, Fletcher CV, Gebo K, Halter JB, Hazzard WR, Horne FM, Huebner RE, Janoff EN, Justice AC, Kuritzkes D, Nayfield SG, Plaeger SF, Schmader KE, Ashworth JR, Campanelli C, Clayton CP, Rada B, Woolard NF, High KP. Aging and infectious diseases: workshop on HIV infection and aging: what is known and future research directions. Clin Infect Dis. 2008 Aug 15; 47(4):542-53. PMID: 18627268.
      View in: PubMed
    62. Meintjes G, Lawn SD, Scano F, Maartens G, French MA, Worodria W, Elliott JH, Murdoch D, Wilkinson RJ, Seyler C, John L, van der Loeff MS, Reiss P, Lynen L, Janoff EN, Gilks C, Colebunders R. Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings. Lancet Infect Dis. 2008 Aug; 8(8):516-23. PMID: 18652998.
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    63. Vacharaksa A, Asrani AC, Gebhard KH, Fasching CE, Giacaman RA, Janoff EN, Ross KF, Herzberg MC. Oral keratinocytes support non-replicative infection and transfer of harbored HIV-1 to permissive cells. Retrovirology. 2008 Jul 17; 5:66. PMID: 18637194.
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    64. Kambugu A, Meya DB, Rhein J, O'Brien M, Janoff EN, Ronald AR, Kamya MR, Mayanja-Kizza H, Sande MA, Bohjanen PR, Boulware DR. Outcomes of cryptococcal meningitis in Uganda before and after the availability of highly active antiretroviral therapy. Clin Infect Dis. 2008 Jun 01; 46(11):1694-701. PMID: 18433339.
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    65. Kunisaki KM, Rice KL, Janoff EN, Rector TS, Niewoehner DE. Exhaled nitric oxide, systemic inflammation, and the spirometric response to inhaled fluticasone propionate in severe chronic obstructive pulmonary disease: a prospective study. Ther Adv Respir Dis. 2008 Apr; 2(2):55-64. PMID: 19124359.
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    66. D'Heilly SJ, Janoff EN, Nichol P, Nichol KL. Rapid diagnosis of influenza infection in older adults: influence on clinical care in a routine clinical setting. J Clin Virol. 2008 Jun; 42(2):124-8. PMID: 18289930.
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    67. Bliss SJ, O'Brien KL, Janoff EN, Cotton MF, Musoke P, Coovadia H, Levine OS. The evidence for using conjugate vaccines to protect HIV-infected children against pneumococcal disease. Lancet Infect Dis. 2008 Jan; 8(1):67-80. PMID: 17974480.
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    68. Mantis NJ, Palaia J, Hessell AJ, Mehta S, Zhu Z, Corth?sy B, Neutra MR, Burton DR, Janoff EN. Inhibition of HIV-1 infectivity and epithelial cell transfer by human monoclonal IgG and IgA antibodies carrying the b12 V region. J Immunol. 2007 Sep 01; 179(5):3144-52. PMID: 17709529.
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    69. Boulware DR, Daley CL, Merrifield C, Hopewell PC, Janoff EN. Rapid diagnosis of pneumococcal pneumonia among HIV-infected adults with urine antigen detection. J Infect. 2007 Oct; 55(4):300-9. PMID: 17692384.
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    70. Shapiro RL, Lockman S, Kim S, Smeaton L, Rahkola JT, Thior I, Wester C, Moffat C, Arimi P, Ndase P, Asmelash A, Stevens L, Montano M, Makhema J, Essex M, Janoff EN. Infant morbidity, mortality, and breast milk immunologic profiles among breast-feeding HIV-infected and HIV-uninfected women in Botswana. J Infect Dis. 2007 Aug 15; 196(4):562-9. PMID: 17624842.
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    71. Nguyen JT, Myers N, Palaia J, Georgopoulos A, Rubins JB, Janoff EN. Humoral responses to oxidized low-density lipoprotein and related bacterial antigens after pneumococcal vaccine. Transl Res. 2007 Sep; 150(3):172-9. PMID: 17761370.
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    72. Fasching CE, Grossman T, Corth?sy B, Plaut AG, Weiser JN, Janoff EN. Impact of the molecular form of immunoglobulin A on functional activity in defense against Streptococcus pneumoniae. Infect Immun. 2007 Apr; 75(4):1801-10. PMID: 17261616.
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    73. Gordon SB, Janoff EN, Sloper D, Zhang Q, Read RC, Zijlstra EE, Finn A, Molyneux ME. HIV-1 infection is associated with altered innate pulmonary immunity. J Infect Dis. 2005 Oct 15; 192(8):1412-6. PMID: 16170759.
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    74. Jarvis GA, Janoff EN, Cheng H, Devita D, Fasching C, McCulloch CE, Murphy EL. Human T lymphotropic virus type II infection and humoral responses to pneumococcal polysaccharide and tetanus toxoid vaccines. J Infect Dis. 2005 Apr 15; 191(8):1239-44. PMID: 15776369.
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    75. King SJ, Hippe KR, Gould JM, Bae D, Peterson S, Cline RT, Fasching C, Janoff EN, Weiser JN. Phase variable desialylation of host proteins that bind to Streptococcus pneumoniae in vivo and protect the airway. Mol Microbiol. 2004 Oct; 54(1):159-71. PMID: 15458413.
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    76. Manigart O, Crepin M, Leroy V, Meda N, Valea D, Janoff EN, Rouet F, Dequae-Merchadoux L, Dabis F, Rouzioux C, Van de Perre P. Effect of perinatal zidovudine prophylaxis on the evolution of cell-free HIV-1 RNA in breast milk and on postnatal transmission. J Infect Dis. 2004 Oct 15; 190(8):1422-8. PMID: 15378434.
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    77. Feikin DR, Feldman C, Schuchat A, Janoff EN. Global strategies to prevent bacterial pneumonia in adults with HIV disease. Lancet Infect Dis. 2004 Jul; 4(7):445-55. PMID: 15219555.
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    78. John-Stewart G, Mbori-Ngacha D, Ekpini R, Janoff EN, Nkengasong J, Read JS, Van de Perre P, Newell ML. Breast-feeding and Transmission of HIV-1. J Acquir Immune Defic Syndr. 2004 Feb 01; 35(2):196-202. PMID: 14722454.
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    79. Janoff EN, Lynfield R. Smallpox: remembrance of things past, or the coming plague? J Lab Clin Med. 2003 Oct; 142(4):211-5. PMID: 14625525.
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    80. Weiser JN, Bae D, Fasching C, Scamurra RW, Ratner AJ, Janoff EN. Antibody-enhanced pneumococcal adherence requires IgA1 protease. Proc Natl Acad Sci U S A. 2003 Apr 01; 100(7):4215-20. PMID: 12642661.
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    81. Janoff EN, Smith PD. Emerging concepts in gastrointestinal aspects of HIV-1 pathogenesis and management. Gastroenterology. 2001 Feb; 120(3):607-21. PMID: 11179239.
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    82. Pillay K, Coutsoudis A, Agadzi-Naqvi AK, Kuhn L, Coovadia HM, Janoff EN. Secretory leukocyte protease inhibitor in vaginal fluids and perinatal human immunodeficiency virus type 1 transmission. J Infect Dis. 2001 Feb 15; 183(4):653-6. PMID: 11170993.
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    83. Carson PJ, Nichol KL, O'Brien J, Hilo P, Janoff EN. Immune function and vaccine responses in healthy advanced elderly patients. Arch Intern Med. 2000 Jul 10; 160(13):2017-24. PMID: 10888975.
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    84. French N, Nakiyingi J, Carpenter LM, Lugada E, Watera C, Moi K, Moore M, Antvelink D, Mulder D, Janoff EN, Whitworth J, Gilks CF. 23-valent pneumococcal polysaccharide vaccine in HIV-1-infected Ugandan adults: double-blind, randomised and placebo controlled trial. Lancet. 2000 Jun 17; 355(9221):2106-11. PMID: 10902624.
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    85. Scamurra RW, Miller DJ, Dahl L, Abrahamsen M, Kapur V, Wahl SM, Milner EC, Janoff EN. Impact of HIV-1 infection on VH3 gene repertoire of naive human B cells. J Immunol. 2000 May 15; 164(10):5482-91. PMID: 10799916.
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    86. French N, Mujugira A, Nakiyingi J, Mulder D, Janoff EN, Gilks CF. Immunologic and clinical stages in HIV-1-infected Ugandan adults are comparable and provide no evidence of rapid progression but poor survival with advanced disease. J Acquir Immune Defic Syndr. 1999 Dec 15; 22(5):509-16. PMID: 10961614.
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    87. Rubins JB, Alter M, Loch J, Janoff EN. Determination of antibody responses of elderly adults to all 23 capsular polysaccharides after pneumococcal vaccination. Infect Immun. 1999 Nov; 67(11):5979-84. PMID: 10531257.
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    88. Janoff EN, Fasching C, Orenstein JM, Rubins JB, Opstad NL, Dalmasso AP. Killing of Streptococcus pneumoniae by capsular polysaccharide-specific polymeric IgA, complement, and phagocytes. J Clin Invest. 1999 Oct; 104(8):1139-47. PMID: 10525053.
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    89. Kaplan JE, Janoff EN, Masur H. Editorial response: do bacterial pneumonia and Pneumocystis carinii pneumonia accelerate progression of human immunodeficiency virus disease? Clin Infect Dis. 1999 Sep; 29(3):544-6. PMID: 10530444.
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    90. Swingler S, Mann A, Jacqu? J, Brichacek B, Sasseville VG, Williams K, Lackner AA, Janoff EN, Wang R, Fisher D, Stevenson M. HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages. Nat Med. 1999 Sep; 5(9):997-103. PMID: 10470075.
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    91. Janoff EN, Rubins JB. Editorial response: Predicting protection against encapsulated pathogens. Clin Infect Dis. 1999 Aug; 29(2):289-91. PMID: 10476728.
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    92. Rubins JB, Cheung S, Carson P, Rubins HB, Janoff EN. Identification of clinical risk factors for nosocomial pneumococcal bacteremia. Clin Infect Dis. 1999 Jul; 29(1):178-83. PMID: 10433582.
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    93. Janoff EN, Tasker SA, Stevenson M, Rubins JB, O'Brien J, Utz G, Weiss P, Hall FW, Wallace MR. Immune activation and virologic response to immunization in recent HIV type 1 seroconverters. AIDS Res Hum Retroviruses. 1999 Jun 10; 15(9):837-45. PMID: 10381172.
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    94. Wahl SM, Smith PD, Janoff EN. Human immunodeficiency virus type 1 infection, mucosal immunity, and pathogenesis: comments and conference summary. J Infect Dis. 1999 May; 179 Suppl 3:S397-400. PMID: 10099105.
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    95. Janoff EN, Scamurra RW, Sanneman TC, Eidman K, Thurn JR. Human immunodeficiency virus type 1 and mucosal humoral defense. J Infect Dis. 1999 May; 179 Suppl 3:S475-9. PMID: 10099123.
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    96. Rubins JB, Paddock AH, Charboneau D, Berry AM, Paton JC, Janoff EN. Pneumolysin in pneumococcal adherence and colonization. Microb Pathog. 1998 Dec; 25(6):337-42. PMID: 9895272.
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    97. French N, Gilks CF, Mujugira A, Fasching C, O'Brien J, Janoff EN. Pneumococcal vaccination in HIV-1-infected adults in Uganda: humoral response and two vaccine failures. AIDS. 1998 Sep 10; 12(13):1683-9. PMID: 9764789.
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    98. Rubins JB, Puri AK, Loch J, Charboneau D, MacDonald R, Opstad N, Janoff EN. Magnitude, duration, quality, and function of pneumococcal vaccine responses in elderly adults. J Infect Dis. 1998 Aug; 178(2):431-40. PMID: 9697723.
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    99. Williams DN, Fasching C, Janoff EN. Septic siblings with pneumonia due to penicillin-resistant Streptococcus pneumoniae. Clin Infect Dis. 1998 May; 26(5):1230-1. PMID: 9597259.
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    100. Anderson MJ, Janoff EN. Klebsiella endocarditis: report of two cases and review. Clin Infect Dis. 1998 Feb; 26(2):468-74. PMID: 9502472.
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    101. Mundy LS, Janoff EN, Schwebke KE, Shanholtzer CJ, Willard KE. Ambiguity in the identification of Streptococcus pneumoniae. Optochin, bile solubility, quellung, and the AccuProbe DNA probe tests. Am J Clin Pathol. 1998 Jan; 109(1):55-61. PMID: 9426518.
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    102. Rubins JB, Janoff EN. Pneumolysin: a multifunctional pneumococcal virulence factor. J Lab Clin Med. 1998 Jan; 131(1):21-7. PMID: 9452123.
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    103. Rubins JB, Janoff EN. Community-acquired pneumonia. Tailoring management of adult patients according to risk category. Postgrad Med. 1997 Dec; 102(6):45-7, 52, 55-62. PMID: 9406562.
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    104. Janoff EN, Hayakawa H, Taylor DN, Fasching CE, Kenner JR, Jaimes E, Raij L. Nitric oxide production during Vibrio cholerae infection. Am J Physiol. 1997 11; 273(5):G1160-7. PMID: 9374715.
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    105. Hibbs JR, Douglas JM, Judson FN, McGill WL, Rietmeijer CA, Janoff EN. Prevalence of human immunodeficiency virus infection, mortality rate, and serogroup distribution among patients with pneumococcal bacteremia at Denver General Hospital, 1984-1994. Clin Infect Dis. 1997 Aug; 25(2):195-9. PMID: 9332509.
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    106. Wahl SM, McNeely TB, Janoff EN, Shugars D, Worley P, Tucker C, Orenstein JM. Secretory leukocyte protease inhibitor (SLPI) in mucosal fluids inhibits HIV-I. Oral Dis. 1997 May; 3 Suppl 1:S64-9. PMID: 9456660.
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    107. Wahl SM, Worley P, Jin W, McNeely TB, Eisenberg S, Fasching C, Orenstein JM, Janoff EN. Anatomic dissociation between HIV-1 and its endogenous inhibitor in mucosal tissues. Am J Pathol. 1997 Apr; 150(4):1275-84. PMID: 9094984.
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    108. Janoff EN, Fasching C, Ojoo JC, O'Brien J, Gilks CF. Responsiveness of human immunodeficiency virus type 1-infected Kenyan women with or without prior pneumococcal disease to pneumococcal vaccine. J Infect Dis. 1997 Apr; 175(4):975-8. PMID: 9086163.
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    109. Smith PD, Janoff EN, Mosteller-Barnum M, Merger M, Orenstein JM, Kearney JF, Graham MF. Isolation and purification of CD14-negative mucosal macrophages from normal human small intestine. J Immunol Methods. 1997 Mar 10; 202(1):1-11. PMID: 9075766.
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    110. Janoff EN, Rubins JB. Invasive pneumococcal disease in the immunocompromised host. Microb Drug Resist. 1997; 3(3):215-32. PMID: 9270991.
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    111. Brichacek B, Swindells S, Janoff EN, Pirruccello S, Stevenson M. Increased plasma human immunodeficiency virus type 1 burden following antigenic challenge with pneumococcal vaccine. J Infect Dis. 1996 Dec; 174(6):1191-9. PMID: 8940208.
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    112. Johnson S, Opstad NL, Douglas JM, Janoff EN. Prolonged and preferential production of polymeric immunoglobulin A in response to Streptococcus pneumoniae capsular polysaccharides. Infect Immun. 1996 Oct; 64(10):4339-44. PMID: 8926108.
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    113. Rubins JB, Charboneau D, Fasching C, Berry AM, Paton JC, Alexander JE, Andrew PW, Mitchell TJ, Janoff EN. Distinct roles for pneumolysin's cytotoxic and complement activities in the pathogenesis of pneumococcal pneumonia. Am J Respir Crit Care Med. 1996 Apr; 153(4 Pt 1):1339-46. PMID: 8616564.
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    114. Forthal DN, Landucci G, Habis A, Laxer M, Javato-Laxer M, Tilles JG, Janoff EN. Age, sex, and household exposure are associated with the acute measles-specific antibody-dependent cellular cytotoxicity antibody response. J Infect Dis. 1995 Dec; 172(6):1587-91. PMID: 7594722.
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    115. Amdahl BM, Rubins JB, Daley CL, Gilks CF, Hopewell PC, Janoff EN. Impaired natural immunity to pneumolysin during human immunodeficiency virus infection in the United States and Africa. Am J Respir Crit Care Med. 1995 Dec; 152(6 Pt 1):2000-4. PMID: 8520768.
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    116. Kline S, Larsen TA, Fieber L, Fishbach R, Greenwood M, Harris R, Kline MW, Tennican PO, Janoff EN. Limited toxicity of prolonged therapy with high doses of amphotericin B lipid complex. Clin Infect Dis. 1995 Nov; 21(5):1154-8. PMID: 8589135.
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    117. Levine J, Dykoski RK, Janoff EN. Candida-associated diarrhea: a syndrome in search of credibility. Clin Infect Dis. 1995 Oct; 21(4):881-6. PMID: 8645834.
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    118. Janoff EN, Wahl SM, Thomas K, Smith PD. Modulation of human immunodeficiency virus type 1 infection of human monocytes by IgA. J Infect Dis. 1995 Sep; 172(3):855-8. PMID: 7658082.
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    119. Opstad NL, Daley CL, Thurn JR, Rubins JB, Merrifield C, Hopewell PC, Janoff EN. Impact of Streptococcus pneumoniae bacteremia and human immunodeficiency virus type 1 on oral mucosal immunity. J Infect Dis. 1995 Aug; 172(2):566-70. PMID: 7622907.
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    120. Johnson S, Sypura WD, Gerding DN, Ewing SL, Janoff EN. Selective neutralization of a bacterial enterotoxin by serum immunoglobulin A in response to mucosal disease. Infect Immun. 1995 Aug; 63(8):3166-73. PMID: 7622244.
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    121. Carson PJ, Schut RL, Simpson ML, O'Brien J, Janoff EN. Antibody class and subclass responses to pneumococcal polysaccharides following immunization of human immunodeficiency virus-infected patients. J Infect Dis. 1995 Aug; 172(2):340-5. PMID: 7622875.
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    122. Weiss PJ, Wallace MR, Oldfield EC, O'Brien J, Janoff EN. Response of recent human immunodeficiency virus seroconverters to the pneumococcal polysaccharide vaccine and Haemophilus influenzae type b conjugate vaccine. J Infect Dis. 1995 May; 171(5):1217-22. PMID: 7751696.
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    123. Stevenson M, Brichacek B, Heinzinger N, Swindells S, Pirruccello S, Janoff E, Emerman M. Molecular basis of cell cycle dependent HIV-1 replication. Implications for control of virus burden. Adv Exp Med Biol. 1995; 374:33-45. PMID: 7572399.
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    124. Rubins JB, Charboneau D, Paton JC, Mitchell TJ, Andrew PW, Janoff EN. Dual function of pneumolysin in the early pathogenesis of murine pneumococcal pneumonia. J Clin Invest. 1995 Jan; 95(1):142-50. PMID: 7814608.
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    125. Peterson PK, Chao CC, Carson P, Hu S, Nichol K, Janoff EN. Levels of tumor necrosis factor alpha, interleukin 6, interleukin 10, and transforming growth factor beta are normal in the serum of the healthy elderly. Clin Infect Dis. 1994 Dec; 19(6):1158-9. PMID: 7888553.
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    126. Johnson S, Driks MR, Tweten RK, Ballard J, Stevens DL, Anderson DJ, Janoff EN. Clinical courses of seven survivors of Clostridium septicum infection and their immunologic responses to alpha toxin. Clin Infect Dis. 1994 Oct; 19(4):761-4. PMID: 7803645.
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    127. Janoff EN, Jackson S, Wahl SM, Thomas K, Peterman JH, Smith PD. Intestinal mucosal immunoglobulins during human immunodeficiency virus type 1 infection. J Infect Dis. 1994 Aug; 170(2):299-307. PMID: 8035014.
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    128. Arpadi SM, Back S, O'Brien J, Janoff EN. Antibodies to pneumococcal capsular polysaccharides in children with human immunodeficiency virus infection given polyvalent pneumococcal vaccine. J Pediatr. 1994 Jul; 125(1):77-9. PMID: 8021792.
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    129. Duane PG, Rubins JB, Weisel HR, Janoff EN. Identification of hydrogen peroxide as a Streptococcus pneumoniae toxin for rat alveolar epithelial cells. Infect Immun. 1993 Oct; 61(10):4392-7. PMID: 8406830.
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    130. Janoff EN, O'Brien J, Thompson P, Ehret J, Meiklejohn G, Duvall G, Douglas JM. Streptococcus pneumoniae colonization, bacteremia, and immune response among persons with human immunodeficiency virus infection. J Infect Dis. 1993 Jan; 167(1):49-56. PMID: 8093364.
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    131. Johnson S, Gerding DN, Janoff EN. Systemic and mucosal antibody responses to toxin A in patients infected with Clostridium difficile. J Infect Dis. 1992 Dec; 166(6):1287-94. PMID: 1431247.
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    132. Janoff EN, Breiman RF, Daley CL, Hopewell PC. Pneumococcal disease during HIV infection. Epidemiologic, clinical, and immunologic perspectives. Ann Intern Med. 1992 Aug 15; 117(4):314-24. PMID: 1637028.
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    133. Rubins JB, Duane PG, Charboneau D, Janoff EN. Toxicity of pneumolysin to pulmonary endothelial cells in vitro. Infect Immun. 1992 May; 60(5):1740-6. PMID: 1563759.
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    134. Smith PD, Quinn TC, Strober W, Janoff EN, Masur H. NIH conference. Gastrointestinal infections in AIDS. Ann Intern Med. 1992 Jan 01; 116(1):63-77. PMID: 1463471.
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    135. Janoff EN, Hardy WD, Smith PD, Wahl SM. Humoral recall responses in HIV infection. Levels, specificity, and affinity of antigen-specific IgG. J Immunol. 1991 Oct 01; 147(7):2130-5. PMID: 1918947.
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    136. Chao CC, Janoff EN, Hu SX, Thomas K, Gallagher M, Tsang M, Peterson PK. Altered cytokine release in peripheral blood mononuclear cell cultures from patients with the chronic fatigue syndrome. Cytokine. 1991 Jul; 3(4):292-8. PMID: 1873478.
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    137. Janoff EN, Orenstein JM, Manischewitz JF, Smith PD. Adenovirus colitis in the acquired immunodeficiency syndrome. Gastroenterology. 1991 Apr; 100(4):976-9. PMID: 2001834.
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    138. Anderson DJ, Kuhns JS, Vasil ML, Gerding DN, Janoff EN. DNA fingerprinting by pulsed field gel electrophoresis and ribotyping to distinguish Pseudomonas cepacia isolates from a nosocomial outbreak. J Clin Microbiol. 1991 Mar; 29(3):648-9. PMID: 2037688.
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    139. Janoff EN, Mead PS, Mead JR, Echeverria P, Bodhidatta L, Bhaibulaya M, Sterling CR, Taylor DN. Endemic Cryptosporidium and Giardia lamblia infections in a Thai orphanage. Am J Trop Med Hyg. 1990 Sep; 43(3):248-56. PMID: 2221219.
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    140. Janoff EN, Taylor DN, Echeverria P, Glode MP, Blaser MJ. Serum antibodies to Giardia lamblia by age in populations in Colorado and Thailand. West J Med. 1990 Mar; 152(3):253-6. PMID: 2333701.
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    141. Janoff EN, Limas C, Gebhard RL, Penley KA. Cryptosporidial carriage without symptoms in the acquired immunodeficiency syndrome (AIDS) Ann Intern Med. 1990 Jan 01; 112(1):75-6. PMID: 2152846.
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    142. Novotny TE, Hopkins RS, Shillam P, Janoff EN. Prevalence of Giardia lamblia and risk factors for infection among children attending day-care facilities in Denver. Public Health Rep. 1990 Jan-Feb; 105(1):72-5. PMID: 2106707.
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    143. Birkhead G, Janoff EN, Vogt RL, Smith PD. Elevated levels of immunoglobulin A to Giardia lamblia during a waterborne outbreak of gastroenteritis. J Clin Microbiol. 1989 Aug; 27(8):1707-10. PMID: 2768460.
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    144. Knisley CV, Engelkirk PG, Pickering LK, West MS, Janoff EN. Rapid detection of giardia antigen in stool with the use of enzyme immunoassays. Am J Clin Pathol. 1989 Jun; 91(6):704-8. PMID: 2729183.
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    145. Janoff EN, Craft JC, Pickering LK, Novotny T, Blaser MJ, Knisley CV, Reller LB. Diagnosis of Giardia lamblia infections by detection of parasite-specific antigens. J Clin Microbiol. 1989 Mar; 27(3):431-5. PMID: 2715318.
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    146. Narkewicz MR, Janoff EN, Sokol RJ, Levin MJ. Blastocystis hominis gastroenteritis in a hemophiliac with acquired immune deficiency syndrome. J Pediatr Gastroenterol Nutr. 1989 Jan; 8(1):125-8. PMID: 2732857.
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    147. Janoff EN, Douglas JM, Gabriel M, Blaser MJ, Davidson AJ, Cohn DL, Judson FN. Class-specific antibody response to pneumococcal capsular polysaccharides in men infected with human immunodeficiency virus type 1. J Infect Dis. 1988 Nov; 158(5):983-90. PMID: 3183430.
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    148. Smith PD, Janoff EN. Infectious diarrhea in human immunodeficiency virus infection. Gastroenterol Clin North Am. 1988 Sep; 17(3):587-98. PMID: 3049364.
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    149. Janoff EN, Smith PD. Perspectives on gastrointestinal infections in AIDS. Gastroenterol Clin North Am. 1988 Sep; 17(3):451-63. PMID: 3049355.
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    150. Janoff EN, Smith PD, Blaser MJ. Acute antibody responses to Giardia lamblia are depressed in patients with AIDS. J Infect Dis. 1988 Apr; 157(4):798-804. PMID: 3346571.
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    151. Anderson DJ, Janoff EN. Herpes zoster infection in a patient on methotrexate given prednisone to prevent post-herpetic neuralgia. Ann Intern Med. 1987 Nov; 107(5):783. PMID: 3662298.
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    152. Janoff EN, Reller LB. Cryptosporidium species, a protean protozoan. J Clin Microbiol. 1987 Jun; 25(6):967-75. PMID: 3298313.
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    153. Campos-Outcalt D, Janoff E. Health care in modern Cuba. West J Med. 1980 Mar; 132(3):265-71. PMID: 7376666.
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