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Anthony N. Gerber

TitleAffiliate - NJH
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

    Collapse Research 
    Collapse research activities and funding
    K08HL077159     (GERBER, ANTHONY N)Sep 29, 2005 - Jun 30, 2010
    Gli1 in murine lung development and differentiation
    Role: Principal Investigator

    R01HL109557     (GERBER, ANTHONY N)Apr 15, 2012 - May 31, 2021
    Role of Klf15 in airway smooth muscle and the response to glucocorticoids
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Sasse SK, Kadiyala V, Danhorn T, Panettieri RA, Phang TL, Gerber AN. Glucocorticoid Receptor ChIP-Seq Identifies PLCD1 as a KLF15 Target that Represses Airway Smooth Muscle Hypertrophy. Am J Respir Cell Mol Biol. 2017 Aug; 57(2):226-237. PMID: 28375666.
      View in: PubMed
    2. Helling BA, Gerber AN, Kadiyala V, Sasse SK, Pedersen BS, Sparks L, Nakano Y, Okamoto T, Evans CM, Yang IV, Schwartz DA. Regulation of MUC5B Expression in Idiopathic Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2017 Jul; 57(1):91-99. PMID: 28272906.
      View in: PubMed
    3. Katial RK, Bensch GW, Busse WW, Chipps BE, Denson JL, Gerber AN, Jacobs JS, Kraft M, Martin RJ, Nair P, Wechsler ME. Changing Paradigms in the Treatment of Severe Asthma: The Role of Biologic Therapies. J Allergy Clin Immunol Pract. 2017 Mar - Apr; 5(2S):S1-S14. PMID: 28143691.
      View in: PubMed
    4. Altonsy MO, Mostafa MM, Gerber AN, Newton R. Long-acting ß2-agonists promote glucocorticoid-mediated repression of NF-?B by enhancing expression of the feedback regulator TNFAIP3. Am J Physiol Lung Cell Mol Physiol. 2017 Mar 01; 312(3):L358-L370. PMID: 28039105.
      View in: PubMed
    5. Gerber AN. Measuring safety of inhaled corticosteroids in asthma. Ann Allergy Asthma Immunol. 2016 Dec; 117(6):577-581. PMID: 27979012.
      View in: PubMed
    6. Sasse SK, Altonsy MO, Kadiyala V, Cao G, Panettieri RA, Gerber AN. Glucocorticoid and TNF signaling converge at A20 (TNFAIP3) to repress airway smooth muscle cytokine expression. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 01; 311(2):L421-32. PMID: 27371733.
      View in: PubMed
    7. Kadiyala V, Sasse SK, Altonsy MO, Berman R, Chu HW, Phang TL, Gerber AN. Cistrome-based Cooperation between Airway Epithelial Glucocorticoid Receptor and NF-?B Orchestrates Anti-inflammatory Effects. J Biol Chem. 2016 Jun 10; 291(24):12673-87. PMID: 27076634; PMCID: PMC4933445 [Available on 06/10/17].
    8. Kadiyala V, Sasse SK, Altonsy MO, Phang TL, Gerber AN. Cistrome Analysis of Glucocorticoid Receptor Activity in Bronchial Epithelial Cells Defines Novel Mechanisms of Steroid Efficacy. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S103. PMID: 27027943; PMCID: PMC5015740 [Available on 03/01/17].
    9. Kraft M, Gerber AN, Szefler SJ, Wechsler ME. Introduction to the 58th Annual Thomas L. Petty Aspen Lung Conference: Asthma 2015: Mechanisms to Personalized Medicine. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S23-4. PMID: 27027947.
      View in: PubMed
    10. Morrison-Nozik A, Anand P, Zhu H, Duan Q, Sabeh M, Prosdocimo DA, Lemieux ME, Nordsborg N, Russell AP, MacRae CA, Gerber AN, Jain MK, Haldar SM. Glucocorticoids enhance muscle endurance and ameliorate Duchenne muscular dystrophy through a defined metabolic program. Proc Natl Acad Sci U S A. 2015 Dec 08; 112(49):E6780-9. PMID: 26598680; PMCID: PMC4679037.
    11. Sasse SK, Zuo Z, Kadiyala V, Zhang L, Pufall MA, Jain MK, Phang TL, Stormo GD, Gerber AN. Response Element Composition Governs Correlations between Binding Site Affinity and Transcription in Glucocorticoid Receptor Feed-forward Loops. J Biol Chem. 2015 Aug 07; 290(32):19756-69. PMID: 26088140; PMCID: PMC4528137.
    12. Gerber AN. Glucocorticoids and the Lung. Adv Exp Med Biol. 2015; 872:279-98. PMID: 26215999.
      View in: PubMed
    13. Sasse SK, Gerber AN. Feed-forward transcriptional programming by nuclear receptors: regulatory principles and therapeutic implications. Pharmacol Ther. 2015 Jan; 145:85-91. PMID: 25168919; PMCID: PMC4322938.
    14. Altonsy MO, Sasse SK, Phang TL, Gerber AN. Context-dependent cooperation between nuclear factor ?B (NF-?B) and the glucocorticoid receptor at a TNFAIP3 intronic enhancer: a mechanism to maintain negative feedback control of inflammation. J Biol Chem. 2014 Mar 21; 289(12):8231-9. PMID: 24500711; PMCID: PMC3961651.
    15. Gerber AN. Glucocorticoids and airway smooth muscle: some answers, more questions. Am J Respir Crit Care Med. 2013 May 15; 187(10):1040-1. PMID: 23675710.
      View in: PubMed
    16. Sasse SK, Mailloux CM, Barczak AJ, Wang Q, Altonsy MO, Jain MK, Haldar SM, Gerber AN. The glucocorticoid receptor and KLF15 regulate gene expression dynamics and integrate signals through feed-forward circuitry. Mol Cell Biol. 2013 Jun; 33(11):2104-15. PMID: 23508109; PMCID: PMC3648070.
    17. Haldar SM, Jeyaraj D, Anand P, Zhu H, Lu Y, Prosdocimo DA, Eapen B, Kawanami D, Okutsu M, Brotto L, Fujioka H, Kerner J, Rosca MG, McGuinness OP, Snow RJ, Russell AP, Gerber AN, Bai X, Yan Z, Nosek TM, Brotto M, Hoppel CL, Jain MK. Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation. Proc Natl Acad Sci U S A. 2012 Apr 24; 109(17):6739-44. PMID: 22493257; PMCID: PMC3340075.
    18. Gerber AN. Genetics of glucocorticoids in asthma. N Engl J Med. 2011 Dec 22; 365(25):2435; author reply 2435-6. PMID: 22187997.
      View in: PubMed
    19. Gerber AN, Sutherland ER. Vitamin D and asthma: another dimension. Am J Respir Crit Care Med. 2011 Dec 15; 184(12):1324-5. PMID: 22174108.
      View in: PubMed
    20. Masuno K, Haldar SM, Jeyaraj D, Mailloux CM, Huang X, Panettieri RA, Jain MK, Gerber AN. Expression profiling identifies Klf15 as a glucocorticoid target that regulates airway hyperresponsiveness. Am J Respir Cell Mol Biol. 2011 Sep; 45(3):642-9. PMID: 21257922; PMCID: PMC3175579.
    21. Gerber AN, Masuno K, Diamond MI. Discovery of selective glucocorticoid receptor modulators by multiplexed reporter screening. Proc Natl Acad Sci U S A. 2009 Mar 24; 106(12):4929-34. PMID: 19255438; PMCID: PMC2660744.
    22. Yun AJ, Lee PY, Gerber AN. Integrating systems biology and medical imaging: understanding disease distribution in the lung model. AJR Am J Roentgenol. 2006 Apr; 186(4):925-30. PMID: 16554557.
      View in: PubMed
    23. Yun AJ, Bazar KA, Gerber A, Lee PY, Daniel SM. The dynamic range of biologic functions and variation of many environmental cues may be declining in the modern age: implications for diseases and therapeutics. Med Hypotheses. 2005; 65(1):173-8. PMID: 15893136.
      View in: PubMed
    24. Yun AJ, Bazar KA, Lee PY, Gerber A, Daniel SM. The smoking gun: many conditions associated with tobacco exposure may be attributable to paradoxical compensatory autonomic responses to nicotine. Med Hypotheses. 2005; 64(6):1073-9. PMID: 15823687.
      View in: PubMed
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