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James H. Finigan

TitleAffiliate - NJH
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED

    Collapse Research 
    Collapse research activities and funding
    F32HL078137     (FINIGAN, JAMES H)Jul 1, 2005 - Jun 30, 2006
    NIH/NHLBI
    Activated Protein C on Endothelial Barrier Function
    Role: Principal Investigator
    K08HL086668     (FINIGAN, JAMES H)Aug 15, 2007 - Jul 31, 2012
    NIH/NHLBI
    Efficacy of Activated Protein C in Ventilator Associated Lung Injury
    Role: Principal Investigator
    R01HL111674     (FINIGAN, JAMES H)Jul 1, 2012 - Jun 30, 2017
    NIH/NHLBI
    ADAM17-NRG-1 Signaling in Acute Lung Injury
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Castaldi PJ, Benet M, Petersen H, Rafaels N, Finigan J, Paoletti M, Marike Boezen H, Vonk JM, Bowler R, Pistolesi M, Puhan MA, Anto J, Wauters E, Lambrechts D, Janssens W, Bigazzi F, Camiciottoli G, Cho MH, Hersh CP, Barnes K, Rennard S, Boorgula MP, Dy J, Hansel NN, Crapo JD, Tesfaigzi Y, Agusti A, Silverman EK, Garcia-Aymerich J. Do COPD subtypes really exist? COPD heterogeneity and clustering in 10 independent cohorts. Thorax. 2017 Jun 21. PMID: 28637835.
      View in: PubMed
    2. Mishra R, Foster D, Vasu VT, Thaikoottathil JV, Kosmider B, Chu HW, Bowler RP, Finigan JH. Cigarette Smoke Induces Human Epidermal Receptor 2-Dependent Changes in Epithelial Permeability. Am J Respir Cell Mol Biol. 2016 Jun; 54(6):853-64. PMID: 26600084; PMCID: PMC4942212 [Available on 06/01/17].
      View in: PubMed, PubMed Central
    3. Brune K, Frank J, Schwingshackl A, Finigan J, Sidhaye VK. Pulmonary epithelial barrier function: some new players and mechanisms. Am J Physiol Lung Cell Mol Physiol. 2015 Apr 15; 308(8):L731-45. PMID: 25637609; PMCID: PMC4747906.
      View in: PubMed, PubMed Central
    4. Finigan JH, Vasu VT, Thaikoottathil JV, Mishra R, Shatat MA, Mason RJ, Kern JA. HER2 activation results in ß-catenin-dependent changes in pulmonary epithelial permeability. Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15; 308(2):L199-207. PMID: 25326580; PMCID: PMC4338945.
      View in: PubMed, PubMed Central
    5. Berman R, Huang C, Jiang D, Finigan JH, Wu Q, Chu HW. MUC18 Differentially Regulates Pro-Inflammatory and Anti-Viral Responses in Human Airway Epithelial Cells. J Clin Cell Immunol. 2014 Oct; 5(5). PMID: 25478290.
      View in: PubMed
    6. Kim J, Vasu VT, Mishra R, Singleton KR, Yoo M, Leach SM, Farias-Hesson E, Mason RJ, Kang J, Ramamoorthy P, Kern JA, Heasley LE, Finigan JH, Tan AC. Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy. Bioinformatics. 2014 Sep 01; 30(17):2393-8. PMID: 24812339; PMCID: PMC4147888.
      View in: PubMed, PubMed Central
    7. Finigan JH, Kern JA. Lung cancer screening: past, present and future. Clin Chest Med. 2013 Sep; 34(3):365-71. PMID: 23993809; PMCID: PMC4102106.
      View in: PubMed, PubMed Central
    8. Finigan JH, Kern JA. Lung cancer: new therapeutic targets, new definitions. Am J Respir Crit Care Med. 2012 Jul 01; 186(1):7-8. PMID: 22753683; PMCID: PMC3400992.
      View in: PubMed, PubMed Central
    9. Finigan JH, Downey GP, Kern JA. Human epidermal growth factor receptor signaling in acute lung injury. Am J Respir Cell Mol Biol. 2012 Oct; 47(4):395-404. PMID: 22652197; PMCID: PMC3488630.
      View in: PubMed, PubMed Central
    10. Finigan JH, Mishra R, Vasu VT, Silveira LJ, Nethery DE, Standiford TJ, Burnham EL, Moss M, Kern JA. Bronchoalveolar lavage neuregulin-1 is elevated in acute lung injury and correlates with inflammation. Eur Respir J. 2013 Feb; 41(2):396-401. PMID: 22599357; PMCID: PMC4140244.
      View in: PubMed, PubMed Central
    11. Carr LL, Finigan JH, Kern JA. Evaluation and treatment of patients with non-small cell lung cancer. Med Clin North Am. 2011 Nov; 95(6):1041-54. PMID: 22032426.
      View in: PubMed
    12. Finigan JH, Faress JA, Wilkinson E, Mishra RS, Nethery DE, Wyler D, Shatat M, Ware LB, Matthay MA, Mason R, Silver RF, Kern JA. Neuregulin-1-human epidermal receptor-2 signaling is a central regulator of pulmonary epithelial permeability and acute lung injury. J Biol Chem. 2011 Mar 25; 286(12):10660-70. PMID: 21247898; PMCID: PMC3060517.
      View in: PubMed, PubMed Central
    13. Lin Z, Natesan V, Shi H, Dong F, Kawanami D, Mahabeleshwar GH, Atkins GB, Nayak L, Cui Y, Finigan JH, Jain MK. Kruppel-like factor 2 regulates endothelial barrier function. Arterioscler Thromb Vasc Biol. 2010 Oct; 30(10):1952-9. PMID: 20651277; PMCID: PMC3095948.
      View in: PubMed, PubMed Central
    14. Finigan JH, Boueiz A, Wilkinson E, Damico R, Skirball J, Pae HH, Damarla M, Hasan E, Pearse DB, Reddy SP, Grigoryev DN, Cheadle C, Esmon CT, Garcia JG, Hassoun PM. Activated protein C protects against ventilator-induced pulmonary capillary leak. Am J Physiol Lung Cell Mol Physiol. 2009 Jun; 296(6):L1002-11. PMID: 19363121; PMCID: PMC2692806.
      View in: PubMed, PubMed Central
    15. Finigan JH. The coagulation system and pulmonary endothelial function in acute lung injury. Microvasc Res. 2009 Jan; 77(1):35-8. PMID: 18938186.
      View in: PubMed
    16. Finigan JH, Dudek SM, Singleton PA, Chiang ET, Jacobson JR, Camp SM, Ye SQ, Garcia JG. Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation. J Biol Chem. 2005 Apr 29; 280(17):17286-93. PMID: 15710622.
      View in: PubMed
    17. Nonas SA, Finigan JH, Gao L, Garcia JG. Functional genomic insights into acute lung injury: role of ventilators and mechanical stress. Proc Am Thorac Soc. 2005; 2(3):188-94. PMID: 16222036.
      View in: PubMed
    18. Grigoryev DN, Finigan JH, Hassoun P, Garcia JG. Science review: searching for gene candidates in acute lung injury. Crit Care. 2004 Dec; 8(6):440-7. PMID: 15566614; PMCID: PMC1065043.
      View in: PubMed, PubMed Central
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