|Institution||University of Colorado Denver - Anschutz Medical Campus|
12700 East 19th Avenue - Mail Stop 8619
Aurora CO 80045
|2013 - 2017||Infectious, Reproductive, Asthma and Pulmonary Conditions (IRAP) Study Section , NIH|
|2003||EU-US Workshop on Molecular Signatures of DNA Damage Induced Stress Response Young Scientist Travel , NIH|
|2002||Aspen Cancer Conference Young Investigator|
|1996||Phi Beta Kappa, College of William and Mary|
|2014 - 2017||Epigenetic marks of in utero exposure to gestational diabetes, NIH-NIDDK: R01-DK100340|
|2014 - 2016||Regulation of mRNA and miRNA expression in IPF by DNA methylation, NIH-NHLBI: R21-HL121572|
|2009 - 2015||Determinants of Environmental Airway Disease (Project 3), NIH-NIEHS: P01-ES18181|
|2009 - 2012||Peripheral Blood Biomarkers for Idiopathic Interstitial Pneumonia, NIH-NHLBI: RC1-HL099571|
|2009 - 2015||Asthma: An Epidemic Caused by Epigenetics?, NIH-NHLBI: R01-HL101251|
|2009 - 2019||External Advisory Committee, West Virginia-IDeA Networks of Biomedical Research Excellence, NIH-NIGMS|
I have a broad background in genomics, genetics, and bioinformatics. As a postdoctoral fellow with John Quackenbush, I identified gene expression fingerprints for molecular classification of tumors and outcome prediction in colon cancer. As an Assistant Research Professor at Duke University and then a Staff Scientist at NIEHS, I worked with David Schwartz to identify novel innate immune genes in mice by using genetic and genomic approaches. As the Deputy Director for the Center for Genes, Environment and Health, I provided oversight of next-generation sequencing, expression profiling, genotyping, and epigenomic technologies at National Jewish Health.
I am currently an Associate Professor in the Division of Pulmonary Sciences and Critical Care Medicine (School of Medicine), Epidemiology (Colorado School of Public Health), and Center for Genes, Environment, and Health (National Jewish Health). The focus of my research at the University of Colorado has largely been on epigenetic regulation and transcriptional profiles in pulmonary fibrosis, asthma, and innate immunity. In this work, we have identified molecular subtypes of pulmonary fibrosis, gene expression profiles of environmental exposures in asthma, and DNA methylation changes associated with the development of asthma and pulmonary fibrosis. I am also collaborating with a number of individuals across campus on epigenetic regulation of gene expression in a variety of diseases including gestational diabetes, maternal health/preterm birth, and chronic beryllium disease.
I teach a course focused on the immunologic basis of human disease (IMMU 7603), am a member of the Human Molecular Genetics and Genomics Program (HMGGP) and mentor a number of junior faculty, postdoctoral fellows, graduate and undergraduate students both in our laboratory (Schwarz|Yang Lab)
and in other Divisions and Departments on the Anschutz Medical Campus.
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