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David A Schwartz

TitleDistinguished Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED

    Collapse Research 
    Collapse research activities and funding
    R13HL174110     (REDENTE, ELIZABETH FRANCES)Apr 1, 2024 - Mar 31, 2025
    NIH
    Aspen Lung Conference Pulmonary Fibrosis - focusing on the future
    Role: Co-Principal Investigator
    P01HL162607     (SCHWARTZ, DAVID ALBERT)Jul 1, 2023 - Jun 30, 2028
    NIH
    Mechanisms Regulating Lung Injury and Early Lung Fibrosis
    Role: Principal Investigator
    R01HL158668     (SCHWARTZ, DAVID ALBERT)Apr 1, 2022 - Mar 31, 2027
    NIH
    Molecular Determinants of Usual Interstitial Pneumonia (UIP)
    Role: Principal Investigator
    I01BX005295     (SCHWARTZ, DAVID ALBERT)Oct 1, 2021 - Sep 30, 2025
    NIH
    lncRNAs, Linking Genetic Susceptibility to Molecular Phenotype in IPF
    Role: Principal Investigator
    UH3HL151865     (SCHWARTZ, DAVID ALBERT)Aug 20, 2020 - Jul 31, 2026
    NIH
    Preclinical Pulmonary Fibrosis, an opportune rare disease cohort
    Role: Principal Investigator
    UG3HL151865     (SCHWARTZ, DAVID ALBERT)Aug 1, 2020 - Jul 31, 2022
    NIH
    Preclinical Pulmonary Fibrosis, an opportune rare disease cohort
    Role: Principal Investigator
    R01HL149836     (SCHWARTZ, DAVID ALBERT)Jun 1, 2020 - May 31, 2025
    NIH
    Genes and Transcripts that Interact with MUC5B in Pulmonary Fibrosis
    Role: Principal Investigator
    R38HL143511     (SCHWARTZ, DAVID ALBERT)Mar 1, 2020 - Feb 28, 2029
    NIH
    Colorado StARR Program (CSP)
    Role: Principal Investigator
    R25ES025476     (BROWN, JARED MICHAEL)Apr 2, 2015 - Mar 31, 2025
    NIH
    Colorado Undergraduate Research in Environmental Health Science
    Role: Co-Principal Investigator
    UH3HL123442     (SCHWARTZ, DAVID ALBERT)Sep 22, 2014 - Jun 30, 2021
    NIH
    MUC5B, a novel therapeutic target for Idiopathic Pulmonary Fibrosis (IPF)
    Role: Principal Investigator
    UH2HL123442     (SCHWARTZ, DAVID ALBERT)Sep 22, 2014 - Jul 26, 2016
    NIH
    MUC5B, a novel therapeutic target for Idiopathic Pulmonary Fibrosis (IPF)
    Role: Principal Investigator
    R33HL120770     (SCHWARTZ, DAVID ALBERT)Aug 8, 2014 - Jun 30, 2019
    NIH
    Functional Genetics in Idiopathic Pulmonary Fibrosis
    Role: Principal Investigator
    R21HL120770     (SCHWARTZ, DAVID ALBERT)Aug 8, 2014 - Jun 30, 2016
    NIH
    Functional Genetics in Idiopathic Pulmonary Fibrosis
    Role: Principal Investigator
    R13HL123270     (KOTTON, DARRELL N.)Jul 1, 2014 - Jun 30, 2015
    NIH
    FASEB SRC on The Lung Epithelium in Health and Disease
    Role: Co-Principal Investigator
    I01BX001534     (SCHWARTZ, DAVID ALBERT)Oct 1, 2012 - Sep 30, 2016
    NIH
    Genetic and Epigenetic Changes in MUC5B and Fibrosing Interstitial Lung Disease
    Role: Principal Investigator
    S10RR031832     (SCHWARTZ, DAVID ALBERT)Jun 15, 2011 - Feb 14, 2013
    NIH
    Supercomputer Linux Cluster for Genomics and Proteomics
    Role: Principal Investigator
    RC1HD063508     (GELFAND, ERWIN WILLIAM)Sep 30, 2009 - Aug 31, 2012
    NIH
    Antenatal Dietary Supplementation is a Risk Factor for Infant Atopy Through Epige
    Role: Co-Principal Investigator
    RC1HL099571     (STEELE, MARK)Sep 30, 2009 - Aug 31, 2012
    NIH
    Peripheral Blood Biomarkers for Idiopathic Interstitial Pneumonia
    Role: Principal Investigator
    RC2HL101715     (SCHWARTZ, DAVID ALBERT)Sep 30, 2009 - Aug 31, 2012
    NIH
    Lung Genomics Research Consortium
    Role: Co-Principal Investigator
    P01ES018181     (SCHWARTZ, DAVID ALBERT)Sep 25, 2009 - Jul 31, 2015
    NIH
    Environmental Determinants of Airway Disease in Children
    Role: Principal Investigator
    R01HL097163     (SCHWARTZ, DAVID ALBERT)Sep 3, 2009 - Jun 30, 2019
    NIH
    Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF)
    Role: Principal Investigator
    R01HL101251     (SCHWARTZ, DAVID ALBERT)Sep 1, 2009 - Jun 30, 2015
    NIH
    Asthma: An Epidemic Caused by Epigenetics?
    Role: Principal Investigator
    R01HL095393     (SCHWARTZ, DAVID ALBERT)Sep 24, 2008 - Jul 31, 2013
    NIH
    Genomic Signatures for Idiopathic Interstitial Pneumonia
    Role: Principal Investigator
    P30ES011961     (DI GIULIO, RICHARD)May 3, 2004 - Mar 31, 2011
    NIH
    Center for Comparative Biology of Vulnerable Populations
    Role: Co-Principal Investigator
    P01ES012496     (SCHWARTZ, DAVID A)Sep 15, 2003 - Jun 30, 2008
    NIH
    The Pathogenesis and Genetics of Environmental Asthma
    Role: Principal Investigator
    U19ES011375     (LINNEY, ELWOOD ALBERT)Sep 25, 2001 - Jul 31, 2009
    NIH
    CENTER FOR ENVIRONMENTAL GENOMICS
    Role: Co-Principal Investigator
    U01HL066604     (SCHWARTZ, DAVID A)Sep 30, 2000 - Jul 31, 2004
    NIH
    MICROARRAY EXPRESSION PROFILING OF RODENT MODELS OF HUMA
    Role: Principal Investigator
    U01HL067467     (STEELE, MARK)Aug 20, 2000 - Jul 31, 2005
    NIH
    A LINKAGE STUDY IN FAMILIAL PULMONARY FIBROSIS
    Role: Co-Principal Investigator
    R01HL062628     (SCHWARTZ, DAVID A)Feb 10, 1999 - Dec 31, 2002
    NIH
    HOST DETERMINANTS OF ORGANIC DUST INDUCED AIRWAY DISEASE
    Role: Principal Investigator
    P01ES009607     (HUNNINGHAKE, GARY W)Nov 1, 1998 - Oct 31, 2004
    NIH
    AIRWAY DISEASE IN CHILDREN FROM RURAL COMMUNITIES
    Role: Co-Principal Investigator
    R01ES007498     (SCHWARTZ, DAVID A)Sep 1, 1995 - May 31, 2005
    NIH
    Biological Determinants of Environmental Airway Injury
    Role: Principal Investigator
    R01ES006537     (SCHWARTZ, DAVID A)Sep 1, 1993 - Aug 31, 1998
    NIH
    GRAIN DUST, ENDOTOXIN, AND AIRFLOW OBSTRUCTION
    Role: Principal Investigator
    K01OH000093     (SCHWARTZ, DAVID A)Jul 1, 1990 - Jun 30, 1993
    NIH
    ASBESTOS-INDUCED PLEURAL FIBROSIS &LUNG RESTRICTION
    Role: Principal Investigator
    K08ES000203     (SCHWARTZ, DAVID A)Apr 1, 1990 - Apr 30, 1995
    NIH
    EPIDEMIOLOGY OF VEGETABLE DUST-INDUCED AIRWAY DISEASE
    Role: Principal Investigator
    U09ES005210     (SMART, ROBERT C)Nov 23, 1988 - Jun 30, 2006
    NIH
    ENVIRONMENTAL HEALTH SCIENCES
    Role: Co-Principal Investigator
    T32HL007085     (SCHWARTZ, DAVID ALBERT)Jul 1, 1975 - Jun 30, 2025
    NIH
    Multi-Disciplinary Research Training in Respiratory Disease
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Montesi SB, Gomez CR, Beers M, Brown R, Chattopadhyay I, Flaherty KR, Garcia CK, Gomperts B, Hariri LP, Hogaboam CM, Jenkins RG, Kaminski N, Kim GHJ, K?nigshoff M, Kolb M, Kotton DN, Kropski JA, Lasky J, Magin CM, Maher TM, McCormick M, Moore BB, Nickerson-Nutter C, Oldham J, Podolanczuk AJ, Raghu G, Rosas I, Rowe SM, Schmidt WT, Schwartz D, Shore JE, Spino C, Craig JM, Martinez FJ. Pulmonary Fibrosis Stakeholder Summit: A Joint NHLBI, Three Lakes Foundation, and Pulmonary Fibrosis Foundation Workshop Report. Am J Respir Crit Care Med. 2024 02 15; 209(4):362-373. PMID: 38113442.
      View in: PubMed
    2. Blumhagen RZ, Kurche JS, Cool CD, Walts AD, Heinz D, Fingerlin TE, Yang IV, Schwartz DA. Spatially distinct molecular patterns of gene expression in idiopathic pulmonary fibrosis. Respir Res. 2023 Nov 17; 24(1):287. PMID: 37978501.
      View in: PubMed
    3. Moll M, Peljto AL, Kim JS, Xu H, Debban CL, Chen X, Menon A, Putman RK, Ghosh AJ, Saferali A, Nishino M, Hatabu H, Hobbs BD, Hecker J, McDermott G, Sparks JA, Wain LV, Allen RJ, Tobin MD, Raby BA, Chun S, Silverman EK, Zamora AC, Ortega VE, Garcia CK, Barr RG, Bleecker ER, Meyers DA, Kaner RJ, Rich SS, Manichaikul A, Rotter JI, Dupuis J, O'Connor GT, Fingerlin TE, Hunninghake GM, Schwartz DA, Cho MH. A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities. Am J Respir Crit Care Med. 2023 10 01; 208(7):791-801. PMID: 37523715.
      View in: PubMed
    4. Guillen-Guio B, Paynton ML, Allen RJ, Chin DPW, Donoghue LJ, Stockwell A, Leavy OC, Hernandez-Beeftink T, Reynolds C, Cullinan P, Martinez F, Booth HL, Fahy WA, Hall IP, Hart SP, Hill MR, Hirani N, Hubbard RB, McAnulty RJ, Millar AB, Navaratnam V, Oballa E, Parfrey H, Saini G, Sayers I, Tobin MD, Whyte MKB, Adegunsoye A, Kaminski N, Shwu-Fan M, Strek ME, Zhang Y, Fingerlin TE, Molina-Molina M, Neighbors M, Sheng XR, Oldham JM, Maher TM, Molyneaux PL, Flores C, Noth I, Schwartz DA, Yaspan BL, Jenkins RG, Wain LV, Hollox EJ. Association study of human leukocyte antigen (HLA) variants and idiopathic pulmonary fibrosis. medRxiv. 2023 Jul 24. PMID: 37546732.
      View in: PubMed
    5. Wu L, Chen X, Khalemsky A, Li D, Zoubeidi T, Lauque D, Alsabri M, Boudi Z, Kumar VA, Paxton J, Tsilimingras D, Kurland L, Schwartz D, Hachimi-Idrissi S, Camargo CA, Liu SW, Savioli G, Intas G, Soni KD, Junhasavasdikul D, Cabello JJT, Rathlev NK, Tazarourte K, Slagman A, Christ M, Singer AJ, Lang E, Ricevuti G, Li X, Liang H, Grossman SA, Bellou A. The Association between Emergency Department Length of Stay and In-Hospital Mortality in Older Patients Using Machine Learning: An Observational Cohort Study. J Clin Med. 2023 Jul 18; 12(14). PMID: 37510865.
      View in: PubMed
    6. Blumhagen RZ, Schwartz DA, Langefeld CD, Fingerlin TE. Identification of influential rare variants in aggregate testing using random forest importance measures. Ann Hum Genet. 2023 07; 87(4):184-195. PMID: 37221924.
      View in: PubMed
    7. Liu Q, Zhou Y, Cogan JD, Mitchell DB, Sheng Q, Zhao S, Bai Y, Ciombor KK, Sabusap CM, Malabanan MM, Markin CR, Douglas K, Ding G, Banovich NE, Nickerson DA, Blue EE, Bamshad MJ, Brown KK, Schwartz DA, Phillips JA, Martinez-Barricarte R, Salisbury ML, Shyr Y, Loyd JE, Kropski JA, Blackwell TS. The Genetic Landscape of Familial Pulmonary Fibrosis. Am J Respir Crit Care Med. 2023 05 15; 207(10):1345-1357. PMID: 36622818.
      View in: PubMed
    8. Peljto AL, Blumhagen RZ, Walts AD, Cardwell J, Powers J, Corte TJ, Dickinson JL, Glaspole I, Moodley YP, Vasakova MK, Bendstrup E, Davidsen JR, Borie R, Crestani B, Dieude P, Bonella F, Costabel U, Gudmundsson G, Donnelly SC, Egan J, Henry MT, Keane MP, Kennedy MP, McCarthy C, McElroy AN, Olaniyi JA, O'Reilly KMA, Richeldi L, Leone PM, Poletti V, Puppo F, Tomassetti S, Luzzi V, Kokturk N, Mogulkoc N, Fiddler CA, Hirani N, Jenkins RG, Maher TM, Molyneaux PL, Parfrey H, Braybrooke R, Blackwell TS, Jackson PD, Nathan SD, Porteous MK, Brown KK, Christie JD, Collard HR, Eickelberg O, Foster EE, Gibson KF, Glassberg M, Kass DJ, Kropski JA, Lederer D, Linderholm AL, Loyd J, Mathai SK, Montesi SB, Noth I, Oldham JM, Palmisciano AJ, Reichner CA, Rojas M, Roman J, Schluger N, Shea BS, Swigris JJ, Wolters PJ, Zhang Y, Prele CMA, Enghelmayer JI, Otaola M, Ryerson CJ, Salinas M, Sterclova M, Gebremariam TH, Myll?rniemi M, Carbone RG, Furusawa H, Hirose M, Inoue Y, Miyazaki Y, Ohta K, Ohta S, Okamoto T, Kim DS, Pardo A, Selman M, Aranda AU, Park MS, Park JS, Song JW, Molina-Molina M, Planas-Cerezales L, Westergren-Thorsson G, Smith AV, Manichaikul AW, Kim JS, Rich SS, Oelsner EC, Barr RG, Rotter JI, Dupuis J, O'Connor G, Vasan RS, Cho MH, Silverman EK, Schwarz MI, Steele MP, Lee JS, Yang IV, Fingerlin TE, Schwartz DA. Idiopathic Pulmonary Fibrosis Is Associated with Common Genetic Variants and Limited Rare Variants. Am J Respir Crit Care Med. 2023 05 01; 207(9):1194-1202. PMID: 36602845.
      View in: PubMed
    9. Wang S, Rao W, Hoffman A, Lin J, Li J, Lin T, Liew AA, Vincent M, Mertens TCJ, Karmouty-Quintana H, Crum CP, Metersky ML, Schwartz DA, Davies PJA, Stephan C, Jyothula SSK, Sheshadri A, Suarez EE, Huang HJ, Engelhardt JF, Dickey BF, Parekh KR, McKeon FD, Xian W. Cloning a profibrotic stem cell variant in idiopathic pulmonary fibrosis. Sci Transl Med. 2023 04 26; 15(693):eabp9528. PMID: 37099633.
      View in: PubMed
    10. Steele MP, Peljto AL, Mathai SK, Humphries S, Bang TJ, Oh A, Teague S, Cicchetti G, Sigakis C, Kropski JA, Loyd JE, Blackwell TS, Brown KK, Schwarz MI, Warren RA, Powers J, Walts AD, Markin C, Fingerlin TE, Yang IV, Lynch DA, Lee JS, Schwartz DA. Incidence and Progression of Fibrotic Lung Disease in an At-Risk Cohort. Am J Respir Crit Care Med. 2023 03 01; 207(5):587-593. PMID: 36094461.
      View in: PubMed
    11. Cooley JC, Javkhlan N, Wilson JA, Foster DG, Edelman BL, Ortiz LA, Schwartz DA, Riches DW, Redente EF. Inhibition of antiapoptotic BCL-2 proteins with ABT-263 induces fibroblast apoptosis, reversing persistent pulmonary fibrosis. JCI Insight. 2023 02 08; 8(3). PMID: 36752201.
      View in: PubMed
    12. Jun G, English AC, Metcalf GA, Yang J, Chaisson MJ, Pankratz N, Menon VK, Salerno WJ, Krasheninina O, Smith AV, Lane JA, Blackwell T, Kang HM, Salvi S, Meng Q, Shen H, Pasham D, Bhamidipati S, Kottapalli K, Arnett DK, Ashley-Koch A, Auer PL, Beutel KM, Bis JC, Blangero J, Bowden DW, Brody JA, Cade BE, Chen YI, Cho MH, Curran JE, Fornage M, Freedman BI, Fingerlin T, Gelb BD, Hou L, Hung YJ, Kane JP, Kaplan R, Kim W, Loos RJF, Marcus GM, Mathias RA, McGarvey ST, Montgomery C, Naseri T, Nouraie SM, Preuss MH, Palmer ND, Peyser PA, Raffield LM, Ratan A, Redline S, Reupena S, Rotter JI, Rich SS, Rienstra M, Ruczinski I, Sankaran VG, Schwartz DA, Seidman CE, Seidman JG, Silverman EK, Smith JA, Stilp A, Taylor KD, Telen MJ, Weiss ST, Williams LK, Wu B, Yanek LR, Zhang Y, Lasky-Su J, Gingras MC, Dutcher SK, Eichler EE, Gabriel S, Germer S, Kim R, Viaud-Martinez KA, Nickerson DA, Luo J, Reiner A, Gibbs RA, Boerwinkle E, Abecasis G, Sedlazeck FJ. Structural variation across 138,134 samples in the TOPMed consortium. Res Sq. 2023 Feb 03. PMID: 36778386.
      View in: PubMed
    13. Chen F, Wang X, Jang SK, Quach BC, Weissenkampen JD, Khunsriraksakul C, Yang L, Sauteraud R, Albert CM, Allred NDD, Arnett DK, Ashley-Koch AE, Barnes KC, Barr RG, Becker DM, Bielak LF, Bis JC, Blangero J, Boorgula MP, Chasman DI, Chavan S, Chen YI, Chuang LM, Correa A, Curran JE, David SP, Fuentes LL, Deka R, Duggirala R, Faul JD, Garrett ME, Gharib SA, Guo X, Hall ME, Hawley NL, He J, Hobbs BD, Hokanson JE, Hsiung CA, Hwang SJ, Hyde TM, Irvin MR, Jaffe AE, Johnson EO, Kaplan R, Kardia SLR, Kaufman JD, Kelly TN, Kleinman JE, Kooperberg C, Lee IT, Levy D, Lutz SM, Manichaikul AW, Martin LW, Marx O, McGarvey ST, Minster RL, Moll M, Moussa KA, Naseri T, North KE, Oelsner EC, Peralta JM, Peyser PA, Psaty BM, Rafaels N, Raffield LM, Reupena MS, Rich SS, Rotter JI, Schwartz DA, Shadyab AH, Sheu WH, Sims M, Smith JA, Sun X, Taylor KD, Telen MJ, Watson H, Weeks DE, Weir DR, Yanek LR, Young KA, Young KL, Zhao W, Hancock DB, Jiang B, Vrieze S, Liu DJ. Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing. Nat Genet. 2023 02; 55(2):291-300. PMID: 36702996.
      View in: PubMed
    14. Jun G, English AC, Metcalf GA, Yang J, Chaisson MJ, Pankratz N, Menon VK, Salerno WJ, Krasheninina O, Smith AV, Lane JA, Blackwell T, Kang HM, Salvi S, Meng Q, Shen H, Pasham D, Bhamidipati S, Kottapalli K, Arnett DK, Ashley-Koch A, Auer PL, Beutel KM, Bis JC, Blangero J, Bowden DW, Brody JA, Cade BE, Chen YI, Cho MH, Curran JE, Fornage M, Freedman BI, Fingerlin T, Gelb BD, Hou L, Hung YJ, Kane JP, Kaplan R, Kim W, Loos RJF, Marcus GM, Mathias RA, McGarvey ST, Montgomery C, Naseri T, Nouraie SM, Preuss MH, Palmer ND, Peyser PA, Raffield LM, Ratan A, Redline S, Reupena S, Rotter JI, Rich SS, Rienstra M, Ruczinski I, Sankaran VG, Schwartz DA, Seidman CE, Seidman JG, Silverman EK, Smith JA, Stilp A, Taylor KD, Telen MJ, Weiss ST, Williams LK, Wu B, Yanek LR, Zhang Y, Lasky-Su J, Gingras MC, Dutcher SK, Eichler EE, Gabriel S, Germer S, Kim R, Viaud-Martinez KA, Nickerson DA, Luo J, Reiner A, Gibbs RA, Boerwinkle E, Abecasis G, Sedlazeck FJ. Structural variation across 138,134 samples in the TOPMed consortium. bioRxiv. 2023 Jan 25. PMID: 36747810.
      View in: PubMed
    15. Wang D, Li W, Albasha N, Griffin L, Chang H, Amaya L, Ganguly S, Zeng L, Keum B, Gonz?lez-Navajas JM, Levin M, AkhavanAghdam Z, Snyder H, Schwartz D, Tao A, Boosherhri LM, Hoffman HM, Rose M, Estrada MV, Varki N, Herdman S, Corr M, Webster NJG, Raz E, Bertin S. Long-term exposure to house dust mites accelerates lung cancer development in mice. J Exp Clin Cancer Res. 2023 Jan 21; 42(1):26. PMID: 36670473.
      View in: PubMed
    16. Dobrinskikh E, Hennessy CE, Kurche JS, Kim E, Estrella AM, Cardwell J, Yang IV, Schwartz DA. Epithelial Endoplasmic Reticulum Stress Enhances the Risk of Muc5b-associated Lung Fibrosis. Am J Respir Cell Mol Biol. 2023 01; 68(1):62-74. PMID: 36108173.
      View in: PubMed
    17. Saunders GRB, Wang X, Chen F, Jang SK, Liu M, Wang C, Gao S, Jiang Y, Khunsriraksakul C, Otto JM, Addison C, Akiyama M, Albert CM, Aliev F, Alonso A, Arnett DK, Ashley-Koch AE, Ashrani AA, Barnes KC, Barr RG, Bartz TM, Becker DM, Bielak LF, Benjamin EJ, Bis JC, Bjornsdottir G, Blangero J, Bleecker ER, Boardman JD, Boerwinkle E, Boomsma DI, Boorgula MP, Bowden DW, Brody JA, Cade BE, Chasman DI, Chavan S, Chen YI, Chen Z, Cheng I, Cho MH, Choquet H, Cole JW, Cornelis MC, Cucca F, Curran JE, de Andrade M, Dick DM, Docherty AR, Duggirala R, Eaton CB, Ehringer MA, Esko T, Faul JD, Fernandes Silva L, Fiorillo E, Fornage M, Freedman BI, Gabrielsen ME, Garrett ME, Gharib SA, Gieger C, Gillespie N, Glahn DC, Gordon SD, Gu CC, Gu D, Gudbjartsson DF, Guo X, Haessler J, Hall ME, Haller T, Harris KM, He J, Herd P, Hewitt JK, Hickie I, Hidalgo B, Hokanson JE, Hopfer C, Hottenga J, Hou L, Huang H, Hung YJ, Hunter DJ, Hveem K, Hwang SJ, Hwu CM, Iacono W, Irvin MR, Jee YH, Johnson EO, Joo YY, Jorgenson E, Justice AE, Kamatani Y, Kaplan RC, Kaprio J, Kardia SLR, Keller MC, Kelly TN, Kooperberg C, Korhonen T, Kraft P, Krauter K, Kuusisto J, Laakso M, Lasky-Su J, Lee WJ, Lee JJ, Levy D, Li L, Li K, Li Y, Lin K, Lind PA, Liu C, Lloyd-Jones DM, Lutz SM, Ma J, M?gi R, Manichaikul A, Martin NG, Mathur R, Matoba N, McArdle PF, McGue M, McQueen MB, Medland SE, Metspalu A, Meyers DA, Millwood IY, Mitchell BD, Mohlke KL, Moll M, Montasser ME, Morrison AC, Mulas A, Nielsen JB, North KE, Oelsner EC, Okada Y, Orr? V, Palmer ND, Palviainen T, Pandit A, Park SL, Peters U, Peters A, Peyser PA, Polderman TJC, Rafaels N, Redline S, Reed RM, Reiner AP, Rice JP, Rich SS, Richmond NE, Roan C, Rotter JI, Rueschman MN, Runarsdottir V, Saccone NL, Schwartz DA, Shadyab AH, Shi J, Shringarpure SS, Sicinski K, Skogholt AH, Smith JA, Smith NL, Sotoodehnia N, Stallings MC, Stefansson H, Stefansson K, Stitzel JA, Sun X, Syed M, Tal-Singer R, Taylor AE, Taylor KD, Telen MJ, Thai KK, Tiwari H, Turman C, Tyrfingsson T, Wall TL, Walters RG, Weir DR, Weiss ST, White WB, Whitfield JB, Wiggins KL, Willemsen G, Willer CJ, Winsvold BS, Xu H, Yanek LR, Yin J, Young KL, Young KA, Yu B, Zhao W, Zhou W, Z?llner S, Zuccolo L, Batini C, Bergen AW, Bierut LJ, David SP, Gagliano Taliun SA, Hancock DB, Jiang B, Munaf? MR, Thorgeirsson TE, Liu DJ, Vrieze S. Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature. 2022 12; 612(7941):720-724. PMID: 36477530.
      View in: PubMed
    18. Borie R, Cardwell J, Konigsberg IR, Moore CM, Zhang W, Sasse SK, Gally F, Dobrinskikh E, Walts A, Powers J, Brancato J, Rojas M, Wolters PJ, Brown KK, Blackwell TS, Nakanishi T, Richards JB, Gerber AN, Fingerlin TE, Sachs N, Pulit SL, Zappala Z, Schwartz DA, Yang IV. Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles of MUC5B and DSP in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2022 11 15; 206(10):1259-1270. PMID: 35816432.
      View in: PubMed
    19. Schwartz DA, Blumhagen RZ, Fingerlin TE. Evolution of the Gain-of-Function MUC5B Promoter Variant. Am J Respir Crit Care Med. 2022 11 15; 206(10):1189-1191. PMID: 35830265.
      View in: PubMed
    20. Kurche JS, Stancil IT, Michalski JE, Yang IV, Schwartz DA. Dysregulated Cell-Cell Communication Characterizes Pulmonary Fibrosis. Cells. 2022 10 21; 11(20). PMID: 36291184.
      View in: PubMed
    21. Partanen JJ, H?pp?l? P, Zhou W, Lehisto AA, Ainola M, Sutinen E, Allen RJ, Stockwell AD, Leavy OC, Oldham JM, Guillen-Guio B, Cox NJ, Hirbo JB, Schwartz DA, Fingerlin TE, Flores C, Noth I, Yaspan BL, Jenkins RG, Wain LV, Ripatti S, Pirinen M, Laitinen T, Kaarteenaho R, Myll?rniemi M, Daly MJ, Koskela JT. Leveraging global multi-ancestry meta-analysis in the study of idiopathic pulmonary fibrosis genetics. Cell Genom. 2022 Oct 12; 2(10):100181. PMID: 36777997.
      View in: PubMed
    22. Lucas SEM, Raspin K, Mackintosh J, Glaspole I, Reynolds PN, Chia C, Grainge C, Kendall P, Troy L, Schwartz DA, Wood-Baker R, Walsh SLF, Moodley Y, Robertson J, Macansh S, Walters EH, Chambers D, Corte TJ, Dickinson JL. Preclinical interstitial lung disease in relatives of familial pulmonary fibrosis patients. Pulmonology. 2023 May-Jun; 29(3):257-260. PMID: 36216738.
      View in: PubMed
    23. Schedel M, Leach SM, Strand MJ, Danhorn T, MacBeth M, Faino AV, Lynch AM, Winn VD, Munoz LL, Forsberg SM, Schwartz DA, Gelfand EW, Hauk PJ. Molecular networks in atopic mothers impact the risk of infant atopy. Allergy. 2023 01; 78(1):244-257. PMID: 35993851.
      View in: PubMed
    24. Stancil IT, Michalski JE, Schwartz DA. An Airway-Centric View of Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2022 08 15; 206(4):410-416. PMID: 35446237.
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    182. Seibold MA, Smith RW, Urbanek C, Groshong SD, Cosgrove GP, Brown KK, Schwarz MI, Schwartz DA, Reynolds SD. The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium. PLoS One. 2013; 8(3):e58658. PMID: 23527003.
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    183. Gao Z, Dosman JA, Rennie DC, Schwartz DA, Yang IV, Beach J, Senthilselvan A. Association of Toll-like receptor 2 gene polymorphisms with lung function in workers in swine operations. Ann Allergy Asthma Immunol. 2013 Jan; 110(1):44-50.e1. PMID: 23244658.
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    184. De Arras L, Seng A, Lackford B, Keikhaee MR, Bowerman B, Freedman JH, Schwartz DA, Alper S. An evolutionarily conserved innate immunity protein interaction network. J Biol Chem. 2013 Jan 18; 288(3):1967-78. PMID: 23209288.
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    185. Lee HY, Seo JB, Steele MP, Schwarz MI, Brown KK, Loyd JE, Talbert JL, Schwartz DA, Lynch DA. High-resolution CT scan findings in familial interstitial pneumonia do not conform to those of idiopathic interstitial pneumonia. Chest. 2012 Dec; 142(6):1577-1583. PMID: 23364926.
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    186. Peljto AL, Steele MP, Fingerlin TE, Hinchcliff ME, Murphy E, Podlusky S, Carns M, Schwarz M, Varga J, Schwartz DA. The pulmonary fibrosis-associated MUC5B promoter polymorphism does not influence the development of interstitial pneumonia in systemic sclerosis. Chest. 2012 Dec; 142(6):1584-1588. PMID: 22576636.
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    187. Koeppen M, McNamee EN, Brodsky KS, Aherne CM, Faigle M, Downey GP, Colgan SP, Evans CM, Schwartz DA, Eltzschig HK. Detrimental role of the airway mucin Muc5ac during ventilator-induced lung injury. Mucosal Immunol. 2013 Jul; 6(4):762-75. PMID: 23187315.
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    188. Leslie KO, Cool CD, Sporn TA, Curran-Everett D, Steele MP, Brown KK, Wahidi MM, Schwartz DA. Familial idiopathic interstitial pneumonia: histopathology and survival in 30 patients. Arch Pathol Lab Med. 2012 Nov; 136(11):1366-76. PMID: 23106582.
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    189. Yang IV, Schwartz DA. Epigenetic mechanisms and the development of asthma. J Allergy Clin Immunol. 2012 Dec; 130(6):1243-55. PMID: 23026498.
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    191. Oakes JL, O'Connor BP, Warg LA, Burton R, Hock A, Loader J, Laflamme D, Jing J, Hui L, Schwartz DA, Yang IV. Ozone enhances pulmonary innate immune response to a Toll-like receptor-2 agonist. Am J Respir Cell Mol Biol. 2013 Jan; 48(1):27-34. PMID: 23002100.
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    192. Pedersen BS, Schwartz DA, Yang IV, Kechris KJ. Comb-p: software for combining, analyzing, grouping and correcting spatially correlated P-values. Bioinformatics. 2012 Nov 15; 28(22):2986-8. PMID: 22954632.
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    193. Yang IV, Schwartz DA. The next generation of complex lung genetic studies. Am J Respir Crit Care Med. 2012 Dec 01; 186(11):1087-94. PMID: 22936355.
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    194. Henao-Mart?nez AF, Schwartz DA, Yang IV. Chagasic cardiomyopathy, from acute to chronic: is this mediated by host susceptibility factors? Trans R Soc Trop Med Hyg. 2012 Sep; 106(9):521-7. PMID: 22819769.
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    195. Macneal K, Schwartz DA. The genetic and environmental causes of pulmonary fibrosis. Proc Am Thorac Soc. 2012 Jul; 9(3):120-5. PMID: 22802285.
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    196. Yang IV, Luna LG, Cotter J, Talbert J, Leach SM, Kidd R, Turner J, Kummer N, Kervitsky D, Brown KK, Boon K, Schwarz MI, Schwartz DA, Steele MP. The peripheral blood transcriptome identifies the presence and extent of disease in idiopathic pulmonary fibrosis. PLoS One. 2012; 7(6):e37708. PMID: 22761659.
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    197. Warg LA, Oakes JL, Burton R, Neidermyer AJ, Rutledge HR, Groshong S, Schwartz DA, Yang IV. The role of the E2F1 transcription factor in the innate immune response to systemic LPS. Am J Physiol Lung Cell Mol Physiol. 2012 Sep; 303(5):L391-400. PMID: 22707615.
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    198. Center DM, Schwartz DA, Solway J, Gail D, Laposky AD, Lin QS, Gan W. Genomic medicine and lung diseases. Am J Respir Crit Care Med. 2012 Aug 01; 186(3):280-5. PMID: 22652029.
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    199. Schwartz DA. Physician-scientists: the bridge between medicine and science. Am J Respir Crit Care Med. 2012 Mar 15; 185(6):595-6. PMID: 22422900.
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    200. De Arras L, Yang IV, Lackford B, Riches DW, Prekeris R, Freedman JH, Schwartz DA, Alper S. Spatiotemporal inhibition of innate immunity signaling by the Tbc1d23 RAB-GAP. J Immunol. 2012 Mar 15; 188(6):2905-13. PMID: 22312129.
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    201. Yang IV, Tomfohr J, Singh J, Foss CM, Marshall HE, Que LG, McElvania-Tekippe E, Florence S, Sundy JS, Schwartz DA. The clinical and environmental determinants of airway transcriptional profiles in allergic asthma. Am J Respir Crit Care Med. 2012 Mar 15; 185(6):620-7. PMID: 22246175.
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    202. Moran Gilad J, Carmeli Y, Schwartz D, Navon-Venezia S. Laboratory evaluation of the CHROMagar KPC medium for identification of carbapenem-nonsusceptible Enterobacteriaceae. Diagn Microbiol Infect Dis. 2011 Aug; 70(4):565-7. PMID: 21767716.
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    203. Yang IV, Rutledge HR, Yang J, Warg LA, Sevilla SD, Schwartz DA. A locus on chromosome 9 is associated with differential response of 129S1/SvImJ and FVB/NJ strains of mice to systemic LPS. Mamm Genome. 2011 Oct; 22(9-10):518-29. PMID: 21720866.
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    204. Yang IV, Jiang W, Rutledge HR, Lackford B, Warg LA, De Arras L, Alper S, Schwartz DA, Pisetsky DS. Identification of novel innate immune genes by transcriptional profiling of macrophages stimulated with TLR ligands. Mol Immunol. 2011 Sep; 48(15-16):1886-95. PMID: 21665277.
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    205. Yang IV, Schwartz DA. Epigenetic control of gene expression in the lung. Am J Respir Crit Care Med. 2011 May 15; 183(10):1295-301. PMID: 21596832.
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    206. Seibold MA, Wise AL, Speer MC, Steele MP, Brown KK, Loyd JE, Fingerlin TE, Zhang W, Gudmundsson G, Groshong SD, Evans CM, Garantziotis S, Adler KB, Dickey BF, du Bois RM, Yang IV, Herron A, Kervitsky D, Talbert JL, Markin C, Park J, Crews AL, Slifer SH, Auerbach S, Roy MG, Lin J, Hennessy CE, Schwarz MI, Schwartz DA. A common MUC5B promoter polymorphism and pulmonary fibrosis. N Engl J Med. 2011 Apr 21; 364(16):1503-12. PMID: 21506741.
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    207. Adler A, Navon-Venezia S, Moran-Gilad J, Marcos E, Schwartz D, Carmeli Y. Laboratory and clinical evaluation of screening agar plates for detection of carbapenem-resistant Enterobacteriaceae from surveillance rectal swabs. J Clin Microbiol. 2011 Jun; 49(6):2239-42. PMID: 21471338.
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    208. Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, Powell CL, Steigerwalt J, Xie Y, Kelada SN, Collins FS, Yang IV, Schwartz DA, Branstetter LA, Chesler EJ, Miller DR, Spence J, Liu EY, McMillan L, Sarkar A, Wang J, Wang W, Zhang Q, Broman KW, Korstanje R, Durrant C, Mott R, Iraqi FA, Pomp D, Threadgill D, de Villena FP, Churchill GA. Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res. 2011 Aug; 21(8):1213-22. PMID: 21406540.
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    209. Kelada SN, Wilson MS, Tavarez U, Kubalanza K, Borate B, Whitehead GS, Maruoka S, Roy MG, Olive M, Carpenter DE, Brass DM, Wynn TA, Cook DN, Evans CM, Schwartz DA, Collins FS. Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice. Am J Respir Cell Mol Biol. 2011 Oct; 45(4):817-24. PMID: 21378263.
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    210. Jin L, Xu LG, Yang IV, Davidson EJ, Schwartz DA, Wurfel MM, Cambier JC. Identification and characterization of a loss-of-function human MPYS variant. Genes Immun. 2011 Jun; 12(4):263-9. PMID: 21248775.
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    211. Rutledge HR, Jiang W, Yang J, Warg LA, Schwartz DA, Pisetsky DS, Yang IV. Gene expression profiles of RAW264.7 macrophages stimulated with preparations of LPS differing in isolation and purity. Innate Immun. 2012 Feb; 18(1):80-8. PMID: 21239457.
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    212. Schwartz DA. Environmental genomics and human health. G Ital Med Lav Ergon. 2011 Jan-Mar; 33(1):31-4. PMID: 21417136.
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    213. Seibold MA, Schwartz DA. The lung: the natural boundary between nature and nurture. Annu Rev Physiol. 2011; 73:457-78. PMID: 21054164.
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    214. Yang IV, Alper S, Lackford B, Rutledge H, Warg LA, Burch LH, Schwartz DA. Novel regulators of the systemic response to lipopolysaccharide. Am J Respir Cell Mol Biol. 2011 Aug; 45(2):393-402. PMID: 21131441.
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    215. Ober C, Butte AJ, Elias JA, Lusis AJ, Gan W, Banks-Schlegel S, Schwartz D. Getting from genes to function in lung disease: a National Heart, Lung, and Blood Institute workshop report. Am J Respir Crit Care Med. 2010 Sep 15; 182(6):732-7. PMID: 20558629.
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    216. Kumpf O, Giamarellos-Bourboulis EJ, Koch A, Hamann L, Mouktaroudi M, Oh DY, Latz E, Lorenz E, Schwartz DA, Ferwerda B, Routsi C, Skalioti C, Kullberg BJ, van der Meer JW, Schlag PM, Netea MG, Zacharowski K, Schumann RR. Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts. Crit Care. 2010; 14(3):R103. PMID: 20525286.
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    217. Schwartz DA. Epigenetics and environmental lung disease. Proc Am Thorac Soc. 2010 May; 7(2):123-5. PMID: 20427583.
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    218. Pastva AM, Walker JK, Maddox LA, Mukherjee S, Giamberardino C, Hsia B, Potts E, Zhu H, Degan S, Sunday ME, Lawson BL, Korfhagen TR, Schwartz DA, Eu JP, Foster WM, McMahon TJ, Que L, Wright JR. Nitric oxide mediates relative airway hyporesponsiveness to lipopolysaccharide in surfactant protein A-deficient mice. Am J Respir Cell Mol Biol. 2011 Feb; 44(2):175-84. PMID: 20348208.
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    219. Garantziotis S, Schwartz DA. Ecogenomics of respiratory diseases of public health significance. Annu Rev Public Health. 2010; 31:37-51 1 p following 51. PMID: 20070197.
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    220. Garantziotis S, Li Z, Potts EN, Lindsey JY, Stober VP, Polosukhin VV, Blackwell TS, Schwartz DA, Foster WM, Hollingsworth JW. TLR4 is necessary for hyaluronan-mediated airway hyperresponsiveness after ozone inhalation. Am J Respir Crit Care Med. 2010 04 01; 181(7):666-75. PMID: 20007931.
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    221. Senthilselvan A, Ch?nard L, Kirychuk S, Predicala B, Schwartz DA, Burch LH, Rennie DC, Willson PJ, Dosman JA. Gender-related tumor necrosis factor-alpha responses in na?ve volunteers with Toll-like receptor 4 polymorphisms exposed in a swine confinement facility. J Interferon Cytokine Res. 2009 Dec; 29(12):781-90. PMID: 19929430.
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    222. Alper S, McElwee MK, Apfeld J, Lackford B, Freedman JH, Schwartz DA. The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity. J Biol Chem. 2010 Jan 15; 285(3):1822-8. PMID: 19923212.
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    223. Hollingsworth JW, Theriot BS, Li Z, Lawson BL, Sunday M, Schwartz DA, Walker JK. Both hematopoietic-derived and non-hematopoietic-derived {beta}-arrestin-2 regulates murine allergic airway disease. Am J Respir Cell Mol Biol. 2010 Sep; 43(3):269-75. PMID: 19805483.
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    224. Yang IV, Wade CM, Kang HM, Alper S, Rutledge H, Lackford B, Eskin E, Daly MJ, Schwartz DA. Identification of novel genes that mediate innate immunity using inbred mice. Genetics. 2009 Dec; 183(4):1535-44. PMID: 19805818.
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    225. Pahwa P, Karunanayake CP, Rennie DC, Chen Y, Schwartz DA, Dosman JA. Association of the TLR4 Asp299Gly polymorphism with lung function in relation to body mass index. BMC Pulm Med. 2009 Sep 21; 9:46. PMID: 19772581.
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    226. Senthilselvan A, Dosman JA, Ch?nard L, Burch LH, Predicala BZ, Sorowski R, Schneberger D, Hurst T, Kirychuk S, Gerdts V, Cormier Y, Rennie DC, Schwartz DA. Toll-like receptor 4 variants reduce airway response in human subjects at high endotoxin levels in a swine facility. J Allergy Clin Immunol. 2009 May; 123(5):1034-40, 1040.e1-2. PMID: 19368968.
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    227. Boon K, Bailey NW, Yang J, Steel MP, Groshong S, Kervitsky D, Brown KK, Schwarz MI, Schwartz DA. Molecular phenotypes distinguish patients with relatively stable from progressive idiopathic pulmonary fibrosis (IPF). PLoS One. 2009; 4(4):e5134. PMID: 19347046.
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    228. Schwartz DA. Gene-environment interactions and airway disease in children. Pediatrics. 2009 Mar; 123 Suppl 3:S151-9. PMID: 19221158.
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    229. Huang YC, Li Z, Carter JD, Soukup JM, Schwartz DA, Yang IV. Fine ambient particles induce oxidative stress and metal binding genes in human alveolar macrophages. Am J Respir Cell Mol Biol. 2009 Nov; 41(5):544-52. PMID: 19251948.
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    230. Brass DM, Wise AL, Schwartz DA. Host-environment interactions in exposure-related diffuse lung diseases. Semin Respir Crit Care Med. 2008 Dec; 29(6):603-9. PMID: 19221958.
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    231. Garantziotis S, Li Z, Potts EN, Kimata K, Zhuo L, Morgan DL, Savani RC, Noble PW, Foster WM, Schwartz DA, Hollingsworth JW. Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice. J Biol Chem. 2009 Apr 24; 284(17):11309-17. PMID: 19164299.
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    232. Boon K, Tomfohr JK, Bailey NW, Garantziotis S, Li Z, Brass DM, Maruoka S, Hollingsworth JW, Schwartz DA. Evaluating genome-wide DNA methylation changes in mice by Methylation Specific Digital Karyotyping. BMC Genomics. 2008 Dec 11; 9:598. PMID: 19077247.
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    233. Hollingsworth JW, Maruoka S, Boon K, Garantziotis S, Li Z, Tomfohr J, Bailey N, Potts EN, Whitehead G, Brass DM, Schwartz DA. In utero supplementation with methyl donors enhances allergic airway disease in mice. J Clin Invest. 2008 Oct; 118(10):3462-9. PMID: 18802477.
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    234. Schwartz DA. Translating the genome. Am J Respir Crit Care Med. 2008 Oct 01; 178(7):662-3. PMID: 18796650.
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    235. Garantziotis S, Zudaire E, Trempus CS, Hollingsworth JW, Jiang D, Lancaster LH, Richardson E, Zhuo L, Cuttitta F, Brown KK, Noble PW, Kimata K, Schwartz DA. Serum inter-alpha-trypsin inhibitor and matrix hyaluronan promote angiogenesis in fibrotic lung injury. Am J Respir Crit Care Med. 2008 Nov 01; 178(9):939-47. PMID: 18703791.
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    236. Marraccini P, Brass DM, Hollingsworth JW, Maruoka S, Garantziotis S, Schwartz DA. Bakery flour dust exposure causes non-allergic inflammation and enhances allergic airway inflammation in mice. Clin Exp Allergy. 2008 Sep; 38(9):1526-35. PMID: 18564331.
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    237. Zaas AK, Liao G, Chien JW, Weinberg C, Shore D, Giles SS, Marr KA, Usuka J, Burch LH, Perera L, Perfect JR, Peltz G, Schwartz DA. Plasminogen alleles influence susceptibility to invasive aspergillosis. PLoS Genet. 2008 Jun 20; 4(6):e1000101. PMID: 18566672.
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    238. Brass DM, Yang IV, Kennedy MP, Whitehead GS, Rutledge H, Burch LH, Schwartz DA. Fibroproliferation in LPS-induced airway remodeling and bleomycin-induced fibrosis share common patterns of gene expression. Immunogenetics. 2008 Jul; 60(7):353-69. PMID: 18553078.
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    239. Brass DM, Hollingsworth JW, Cinque M, Li Z, Potts E, Toloza E, Foster WM, Schwartz DA. Chronic LPS inhalation causes emphysema-like changes in mouse lung that are associated with apoptosis. Am J Respir Cell Mol Biol. 2008 Nov; 39(5):584-90. PMID: 18539952.
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    240. Ben-Ami R, Weinberger M, Orni-Wasserlauff R, Schwartz D, Itzhaki A, Lazarovitch T, Bash E, Aharoni Y, Moroz I, Giladi M. Time to blood culture positivity as a marker for catheter-related candidemia. J Clin Microbiol. 2008 Jul; 46(7):2222-6. PMID: 18480222.
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    241. Alper S, Laws R, Lackford B, Boyd WA, Dunlap P, Freedman JH, Schwartz DA. Identification of innate immunity genes and pathways using a comparative genomics approach. Proc Natl Acad Sci U S A. 2008 May 13; 105(19):7016-21. PMID: 18463287.
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    242. Senthilselvan A, Rennie D, Ch?nard L, Burch LH, Babiuk L, Schwartz DA, Dosman JA. Association of polymorphisms of toll-like receptor 4 with a reduced prevalence of hay fever and atopy. Ann Allergy Asthma Immunol. 2008 May; 100(5):463-8. PMID: 18517079.
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    243. Garantziotis S, Hollingsworth JW, Zaas AK, Schwartz DA. The effect of toll-like receptors and toll-like receptor genetics in human disease. Annu Rev Med. 2008; 59:343-59. PMID: 17845139.
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    244. Driehuys B, Walker J, Pollaro J, Cofer GP, Mistry N, Schwartz D, Johnson GA. 3He MRI in mouse models of asthma. Magn Reson Med. 2007 Nov; 58(5):893-900. PMID: 17969115.
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    245. Garantziotis S, Palmer SM, Snyder LD, Ganous T, Chen BJ, Wang T, Cook DN, Schwartz DA. Alloimmune lung injury induced by local innate immune activation through inhaled lipopolysaccharide. Transplantation. 2007 Oct 27; 84(8):1012-9. PMID: 17989607.
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    246. Jaberi A, Schwartz D, Marticorena R, Dacouris N, Prabhudesai V, McFarlane P, Donnelly S. Risk factors for the development of cephalic arch stenosis. J Vasc Access. 2007 Oct-Dec; 8(4):287-95. PMID: 18161676.
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    247. Hollingsworth JW, Maruoka S, Li Z, Potts EN, Brass DM, Garantziotis S, Fong A, Foster WM, Schwartz DA. Ambient ozone primes pulmonary innate immunity in mice. J Immunol. 2007 Oct 01; 179(7):4367-75. PMID: 17878331.
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    248. Garantziotis S, Hollingsworth JW, Ghanayem RB, Timberlake S, Zhuo L, Kimata K, Schwartz DA. Inter-alpha-trypsin inhibitor attenuates complement activation and complement-induced lung injury. J Immunol. 2007 Sep 15; 179(6):4187-92. PMID: 17785858.
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    249. Hollingsworth JW, Whitehead G, Berman KG, Tekippe EM, Gilmour MI, Larkin JE, Quackenbush J, Schwartz DA. Genetic basis of murine antibacterial defense to streptococcal lung infection. Immunogenetics. 2007 Sep; 59(9):713-24. PMID: 17701033.
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    250. Alper S, McBride SJ, Lackford B, Freedman JH, Schwartz DA. Specificity and complexity of the Caenorhabditis elegans innate immune response. Mol Cell Biol. 2007 Aug; 27(15):5544-53. PMID: 17526726.
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    251. Brass DM, Hollingsworth JW, Fessler MB, Savov JD, Maxwell AB, Whitehead GS, Burch LH, Schwartz DA. The IL-1 type 1 receptor is required for the development of LPS-induced airways disease. J Allergy Clin Immunol. 2007 Jul; 120(1):121-7. PMID: 17512577.
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    252. Raj JU, Aliferis C, Caprioli RM, Cowley AW, Davies PF, Duncan MW, Erle DJ, Erzurum SC, Finn PW, Ischiropoulos H, Kaminski N, Kleeberger SR, Leikauf GD, Loyd JE, Martin TR, Matalon S, Moore JH, Quackenbush J, Sabo-Attwood T, Shapiro SD, Schnitzer JE, Schwartz DA, Schwiebert LM, Sheppard D, Ware LB, Weiss ST, Whitsett JA, Wurfel MM, Matthay MA. Genomics and proteomics of lung disease: conference summary. Am J Physiol Lung Cell Mol Physiol. 2007 Jul; 293(1):L45-51. PMID: 17468134.
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    253. Hollingsworth JW, Li Z, Brass DM, Garantziotis S, Timberlake SH, Kim A, Hossain I, Savani RC, Schwartz DA. CD44 regulates macrophage recruitment to the lung in lipopolysaccharide-induced airway disease. Am J Respir Cell Mol Biol. 2007 Aug; 37(2):248-53. PMID: 17446529.
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    254. Shofer S, Badea C, Auerbach S, Schwartz DA, Johnson GA. A micro-computed tomography-based method for the measurement of pulmonary compliance in healthy and bleomycin-exposed mice. Exp Lung Res. 2007 Apr-May; 33(3-4):169-83. PMID: 17558678.
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    255. Brass DM, Hollingsworth JW, McElvania-Tekippe E, Garantziotis S, Hossain I, Schwartz DA. CD14 is an essential mediator of LPS-induced airway disease. Am J Physiol Lung Cell Mol Physiol. 2007 Jul; 293(1):L77-83. PMID: 17384086.
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    256. Palmer SM, Klimecki W, Yu L, Reinsmoen NL, Snyder LD, Ganous TM, Burch L, Schwartz DA. Genetic regulation of rejection and survival following human lung transplantation by the innate immune receptor CD14. Am J Transplant. 2007 Mar; 7(3):693-9. PMID: 17217435.
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    257. Brass DM, Tomfohr J, Yang IV, Schwartz DA. Using mouse genomics to understand idiopathic interstitial fibrosis. Proc Am Thorac Soc. 2007 Jan; 4(1):92-100. PMID: 17202297.
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    258. Schwartz DA. The importance of gene-environment interactions and exposure assessment in understanding human diseases. J Expo Sci Environ Epidemiol. 2006 Nov; 16(6):474-6. PMID: 17109021.
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    259. Bolger MS, Ross DS, Jiang H, Frank MM, Ghio AJ, Schwartz DA, Wright JR. Complement levels and activity in the normal and LPS-injured lung. Am J Physiol Lung Cell Mol Physiol. 2007 Mar; 292(3):L748-59. PMID: 17071722.
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    260. Snyder LD, Hartwig MG, Ganous T, Davis RD, Herczyk WF, Reinsmoen NL, Schwartz DA, Palmer SM. Cytokine gene polymorphisms are not associated with bronchiolitis obliterans syndrome or survival after lung transplant. J Heart Lung Transplant. 2006 Nov; 25(11):1330-5. PMID: 17097497.
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    261. Whitehead GS, Burch LH, Berman KG, Piantadosi CA, Schwartz DA. Genetic basis of murine responses to hyperoxia-induced lung injury. Immunogenetics. 2006 Oct; 58(10):793-804. PMID: 17001473.
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    262. Yang IV, Burch LH, Steele MP, Savov JD, Hollingsworth JW, McElvania-Tekippe E, Berman KG, Speer MC, Sporn TA, Brown KK, Schwarz MI, Schwartz DA. Gene expression profiling of familial and sporadic interstitial pneumonia. Am J Respir Crit Care Med. 2007 Jan 01; 175(1):45-54. PMID: 16998095.
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    263. Schwartz DA. Future of toxicology--a shift in the paradigm: focus on human disease. Chem Res Toxicol. 2006 Sep; 19(9):1121-4. PMID: 16978015.
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    264. Garantziotis S, Brass DM, Savov J, Hollingsworth JW, McElvania-TeKippe E, Berman K, Walker JK, Schwartz DA. Leukocyte-derived IL-10 reduces subepithelial fibrosis associated with chronically inhaled endotoxin. Am J Respir Cell Mol Biol. 2006 Dec; 35(6):662-7. PMID: 16809636.
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    265. Burch LH, Yang IV, Whitehead GS, Chao FG, Berman KG, Schwartz DA. The transcriptional response to lipopolysaccharide reveals a role for interferon-gamma in lung neutrophil recruitment. Am J Physiol Lung Cell Mol Physiol. 2006 Oct; 291(4):L677-82. PMID: 16766576.
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    266. Hollingsworth JW, Whitehead GS, Lin KL, Nakano H, Gunn MD, Schwartz DA, Cook DN. TLR4 signaling attenuates ongoing allergic inflammation. J Immunol. 2006 May 15; 176(10):5856-62. PMID: 16670292.
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    267. Walker JK, Ahumada A, Frank B, Gaspard R, Berman K, Quackenbush J, Schwartz DA. Multistrain genetic comparisons reveal CCR5 as a receptor involved in airway hyperresponsiveness. Am J Respir Cell Mol Biol. 2006 Jun; 34(6):711-8. PMID: 16474097.
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    268. Sundy JS, Wood WA, Watt JL, Kline JN, Schwartz DA. Safety of incremental inhaled lipopolysaccharide challenge in humans. J Endotoxin Res. 2006; 12(2):113-9. PMID: 16690014.
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    269. Palmer SM, Burch LH, Mir S, Smith SR, Kuo PC, Herczyk WF, Reinsmoen NL, Schwartz DA. Donor polymorphisms in Toll-like receptor-4 influence the development of rejection after renal transplantation. Clin Transplant. 2006 Jan-Feb; 20(1):30-6. PMID: 16556150.
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    270. Cook DN, Whitehead GS, Burch LH, Berman KG, Kapadia Z, Wohlford-Lenane C, Schwartz DA. Spontaneous mutations in recombinant inbred mice: mutant toll-like receptor 4 (Tlr4) in BXD29 mice. Genetics. 2006 Mar; 172(3):1751-5. PMID: 16322526.
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    271. Schwartz DA, Cook DN. Polymorphisms of the Toll-like receptors and human disease. Clin Infect Dis. 2005 Nov 15; 41 Suppl 7:S403-7. PMID: 16237638.
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    272. Huerta MF, Farber GK, Wilder EL, Kleinman DV, Grady PA, Schwartz DA, Tabak LA. NIH Roadmap interdisciplinary research initiatives. PLoS Comput Biol. 2005 Nov; 1(6):e59. PMID: 16322762.
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    273. Schwartz DA, Weis B, Wilson SH. The need for exposure health sciences. Environ Health Perspect. 2005 Oct; 113(10):A650. PMID: 16203220.
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    284. Palmer SM, Burch LH, Trindade AJ, Davis RD, Herczyk WF, Reinsmoen NL, Schwartz DA. Innate immunity influences long-term outcomes after human lung transplant. Am J Respir Crit Care Med. 2005 Apr 01; 171(7):780-5. PMID: 15640363.
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    285. Zhang X, Gainetdinov RR, Beaulieu JM, Sotnikova TD, Burch LH, Williams RB, Schwartz DA, Krishnan KR, Caron MG. Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron. 2005 Jan 06; 45(1):11-6. PMID: 15629698.
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    287. Navon-Venezia S, Leavitt A, Ben-Ami R, Aharoni Y, Schwaber MJ, Schwartz D, Carmeli Y. Evaluation of an accelerated protocol for detection of extended-spectrum beta-lactamase-producing gram-negative bacilli from positive blood cultures. J Clin Microbiol. 2005 Jan; 43(1):439-41. PMID: 15635009.
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    294. Garantziotis S, Steele MP, Schwartz DA. Pulmonary fibrosis: thinking outside of the lung. J Clin Invest. 2004 Aug; 114(3):319-21. PMID: 15286797.
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    297. Black DW, Carney CP, Peloso PM, Woolson RF, Schwartz DA, Voelker MD, Barrett DH, Doebbeling BN. Gulf War veterans with anxiety: prevalence, comorbidity, and risk factors. Epidemiology. 2004 Mar; 15(2):135-42. PMID: 15127904.
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    303. El-Sayed NM, Ghedin E, Song J, MacLeod A, Bringaud F, Larkin C, Wanless D, Peterson J, Hou L, Taylor S, Tweedie A, Biteau N, Khalak HG, Lin X, Mason T, Hannick L, Caler E, Blandin G, Bartholomeu D, Simpson AJ, Kaul S, Zhao H, Pai G, Van Aken S, Utterback T, Haas B, Koo HL, Umayam L, Suh B, Gerrard C, Leech V, Qi R, Zhou S, Schwartz D, Feldblyum T, Salzberg S, Tait A, Turner CM, Ullu E, White O, Melville S, Adams MD, Fraser CM, Donelson JE. The sequence and analysis of Trypanosoma brucei chromosome II. Nucleic Acids Res. 2003 Aug 15; 31(16):4856-63. PMID: 12907728.
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    304. Walker JK, Fong AM, Lawson BL, Savov JD, Patel DD, Schwartz DA, Lefkowitz RJ. Beta-arrestin-2 regulates the development of allergic asthma. J Clin Invest. 2003 Aug; 112(4):566-74. PMID: 12925697.
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    307. Palmer SM, Burch LH, Davis RD, Herczyk WF, Howell DN, Reinsmoen NL, Schwartz DA. The role of innate immunity in acute allograft rejection after lung transplantation. Am J Respir Crit Care Med. 2003 Sep 15; 168(6):628-32. PMID: 12773319.
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    311. Balmes J, Becklake M, Blanc P, Henneberger P, Kreiss K, Mapp C, Milton D, Schwartz D, Toren K, Viegi G. American Thoracic Society Statement: Occupational contribution to the burden of airway disease. Am J Respir Crit Care Med. 2003 Mar 01; 167(5):787-97. PMID: 12598220.
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    312. Navon-Venezia S, Hammer-Munz O, Schwartz D, Turner D, Kuzmenko B, Carmeli Y. Occurrence and phenotypic characteristics of extended-spectrum beta-lactamases among members of the family Enterobacteriaceae at the Tel-Aviv Medical Center (Israel) and evaluation of diagnostic tests. J Clin Microbiol. 2003 Jan; 41(1):155-8. PMID: 12517841.
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    318. Barrett DH, Doebbeling CC, Schwartz DA, Voelker MD, Falter KH, Woolson RF, Doebbeling BN. Posttraumatic stress disorder and self-reported physical health status among U.S. Military personnel serving during the Gulf War period: a population-based study. Psychosomatics. 2002 May-Jun; 43(3):195-205. PMID: 12075034.
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    338. Schwartz DA. Etiology and pathogenesis of airway disease in children and adults from rural communities. Environ Health Perspect. 1999 Jun; 107 Suppl 3:393-401. PMID: 10346988.
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    343. Peiffer-Schneider S, Schutte BC, Murray JC, Frees KL, Williamson K, Leysens NJ, Schwartz DA. Exclusion of Ifa and Ifb as the Lps gene and mapping of three markers near the Lps locus. Mamm Genome. 1997 Oct; 8(10):785-6. PMID: 9321479.
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    348. Saag KG, Kolluri S, Koehnke RK, Georgou TA, Rachow JW, Hunninghake GW, Schwartz DA. Rheumatoid arthritis lung disease. Determinants of radiographic and physiologic abnormalities. Arthritis Rheum. 1996 Oct; 39(10):1711-9. PMID: 8843862.
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    350. Jagielo PJ, Thorne PS, Watt JL, Frees KL, Quinn TJ, Schwartz DA. Grain dust and endotoxin inhalation challenges produce similar inflammatory responses in normal subjects. Chest. 1996 Jul; 110(1):263-70. PMID: 8681637.
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    355. Quinn TJ, Donham KJ, Merchant JA, Schwartz DA. Peak flow as a measure of airway dysfunction in swine confinement operators. Chest. 1995 May; 107(5):1303-8. PMID: 7750323.
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    356. Dayton CS, Schwartz DA, Sprince NL, Yagla SJ, Davis CS, Koehnke RK, Furst DE, Hunninghake GW. Low-dose methotrexate may cause air trapping in patients with rheumatoid arthritis. Am J Respir Crit Care Med. 1995 Apr; 151(4):1189-93. PMID: 7697251.
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    362. Hunninghake GW, Gilbert S, Pueringer R, Dayton C, Floerchinger C, Helmers R, Merchant R, Wilson J, Galvin J, Schwartz D. Outcome of the treatment for sarcoidosis. Am J Respir Crit Care Med. 1994 Apr; 149(4 Pt 1):893-8. PMID: 8143052.
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    371. Siegman-Igra Y, Kulka T, Schwartz D, Konforti N. The significance of polymicrobial growth in urine: contamination or true infection. Scand J Infect Dis. 1993; 25(1):85-91. PMID: 8460355.
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    372. Dayton CS, Schwartz DA, Helmers RA, Pueringer RJ, Gilbert SR, Merchant RK, Hunninghake GW. Outcome of subjects with idiopathic pulmonary fibrosis who fail corticosteroid therapy. Implications for further studies. Chest. 1993 Jan; 103(1):69-73. PMID: 8417939.
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    373. Hempel SL, Schwartz DA, Hunninghake GW. The mast cell and idiopathic pulmonary fibrosis. Mayo Clin Proc. 1992 Oct; 67(10):1009-10. PMID: 1434849.
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    374. Schmidt LE, Thorne PS, Watt JL, Schwartz DA. Is an abbreviated bronchial challenge with histamine valid? Chest. 1992 Jan; 101(1):141-5. PMID: 1729060.
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    375. Schwartz DA. The clinical relevance of asbestos-induced pleural fibrosis. Ann N Y Acad Sci. 1991 Dec 31; 643:169-77. PMID: 1809130.
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    376. Schwartz DA, Helmers RA, Dayton CS, Merchant RK, Hunninghake GW. Determinants of bronchoalveolar lavage cellularity in idiopathic pulmonary fibrosis. J Appl Physiol (1985). 1991 Nov; 71(5):1688-93. PMID: 1761464.
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    377. Schwartz DA, Merchant RK, Helmers RA, Gilbert SR, Dayton CS, Hunninghake GW. The influence of cigarette smoking on lung function in patients with idiopathic pulmonary fibrosis. Am Rev Respir Dis. 1991 Sep; 144(3 Pt 1):504-6. PMID: 1892287.
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    378. Landas SK, Schwartz DA. Mica-associated pulmonary interstitial fibrosis. Am Rev Respir Dis. 1991 Sep; 144(3 Pt 1):718-21. PMID: 1892315.
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    379. Peterson MW, Geist LJ, Schwartz DA, Konicek S, Moseley PL. Outcome after cardiopulmonary resuscitation in a medical intensive care unit. Chest. 1991 Jul; 100(1):168-74. PMID: 2060338.
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    380. Schwartz DA. New developments in asbestos-induced pleural disease. Chest. 1991 Jan; 99(1):191-8. PMID: 1984952.
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    381. Schwartz DA, Galvin JR, Dayton CS, Stanford W, Merchant JA, Hunninghake GW. Determinants of restrictive lung function in asbestos-induced pleural fibrosis. J Appl Physiol (1985). 1990 May; 68(5):1932-7. PMID: 2361895.
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    382. Schwartz DA, Smith DD, Lakshminarayan S. The pulmonary sequelae associated with accidental inhalation of chlorine gas. Chest. 1990 Apr; 97(4):820-5. PMID: 2323253.
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    383. Auroux MR, Mayaux MJ, Guihard-Moscato ML, Fromantin M, Barthe J, Schwartz D. Paternal age and mental functions of progeny in man. Hum Reprod. 1989 Oct; 4(7):794-7. PMID: 2606957.
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    384. Schwartz DA, Rosenstock L, Clark JG. Monocyte-derived growth factors in asbestos-induced interstitial fibrosis. Environ Res. 1989 Aug; 49(2):283-94. PMID: 2473896.
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    385. Schwartz DA, Baker EL. Respiratory illness in the construction industry. Airflow obstruction among painters. Chest. 1988 Jan; 93(1):134-7. PMID: 3335144.
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