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Hua Huang

TitleAffiliate - NJH
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-IMM MICRO GENERAL OPER

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Gao J, Li Y, Guan X, Mohammed Z, Gomez G, Hui Y, Zhao D, Oskeritzian CA, Huang H. IL-33 priming and antigenic stimulation synergistically promote the transcription of proinflammatory cytokine and chemokine genes in human skin mast cells. BMC Genomics. 2023 Oct 06; 24(1):592. PMID: 37798647.
      View in: PubMed
    2. Li Y, Gao J, Zhao D, Guan X, Morris SC, Finkelman FD, Huang H. The Hdc GC box is critical for Hdc gene transcription and histamine-mediated anaphylaxis. J Allergy Clin Immunol. 2023 07; 152(1):195-204.e3. PMID: 36804390.
      View in: PubMed
    3. Li Y, Qi X, Zhao D, Urban JF, Huang H. IL-3 Expands Pre-Basophil and Mast Cell Progenitors by Upregulating the IL-3 Receptor Expression. Cell Immunol. 2022 04; 374:104498. PMID: 35334276.
      View in: PubMed
    4. Bridges JP, Vladar EK, Huang H, Mason RJ. Respiratory epithelial cell responses to SARS-CoV-2 in COVID-19. Thorax. 2022 02; 77(2):203-209. PMID: 34404754.
      View in: PubMed
    5. Most JF, Ambrose CS, Chung Y, Kreindler JL, Near A, Brunton S, Cao Y, Huang H, Zhao X. Real-World Assessment of Asthma Specialist Visits Among U.S. Patients with Severe Asthma. J Allergy Clin Immunol Pract. 2021 10; 9(10):3662-3671.e1. PMID: 34148858.
      View in: PubMed
    6. Li Y, Gao J, Kamran M, Harmacek L, Danhorn T, Leach SM, O'Connor BP, Hagman JR, Huang H. GATA2 regulates mast cell identity and responsiveness to antigenic stimulation by promoting chromatin remodeling at super-enhancers. Nat Commun. 2021 01 21; 12(1):494. PMID: 33479210.
      View in: PubMed
    7. Kamran M, Liang J, Liu B, Li Y, Gao J, Keating A, Mohamed F, Dai S, Reinhardt R, Jiong Y, Wu Z, Huang H. The Clusters of Transcription Factors NFATC2, STAT5, GATA2, AP1, RUNX1 and EGR2 Binding Sites at the Induced Il13 Enhancers Mediate Il13 Gene Transcription in Response to Antigenic Stimulation. J Immunol. 2020 12 15; 205(12):3311-3318. PMID: 33188077.
      View in: PubMed
    8. Huang H, Li Y, Liang J, Finkelman FD. Molecular Regulation of Histamine Synthesis. Front Immunol. 2018; 9:1392. PMID: 29973935.
      View in: PubMed
    9. Li Y, Liu B, Harmacek L, Long Z, Liang J, Lukin K, Leach SM, O'Connor B, Gerber AN, Hagman J, Roers A, Finkelman FD, Huang H. The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis. J Allergy Clin Immunol. 2018 10; 142(4):1173-1184. PMID: 29277702.
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    10. Born WK, Huang Y, Reinhardt RL, Huang H, Sun D, O'Brien RL. ?d T Cells and B Cells. Adv Immunol. 2017; 134:1-45. PMID: 28413020.
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    11. Huang H, Li Y, Liu B. Transcriptional regulation of mast cell and basophil lineage commitment. Semin Immunopathol. 2016 09; 38(5):539-48. PMID: 27126100.
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    12. Huang Y, Getahun A, Heiser RA, Detanico TO, Aviszus K, Kirchenbaum GA, Casper TL, Huang C, Aydintug MK, Carding SR, Ikuta K, Huang H, Wysocki LJ, Cambier JC, O'Brien RL, Born WK. ?d T Cells Shape Preimmune Peripheral B Cell Populations. J Immunol. 2016 Jan 01; 196(1):217-31. PMID: 26582947.
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    13. Huang Y, Yang Z, McGowan J, Huang H, O'Brien RL, Born WK. Regulation of IgE Responses by ?d T Cells. Curr Allergy Asthma Rep. 2015 Apr; 15(4):13. PMID: 26130476.
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    14. Li Y, Qi X, Liu B, Huang H. The STAT5-GATA2 pathway is critical in basophil and mast cell differentiation and maintenance. J Immunol. 2015 May 01; 194(9):4328-38. PMID: 25801432.
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    15. Huang Y, Heiser RA, Detanico TO, Getahun A, Kirchenbaum GA, Casper TL, Aydintug MK, Carding SR, Ikuta K, Huang H, Cambier JC, Wysocki LJ, O'Brien RL, Born WK. ?d T cells affect IL-4 production and B-cell tolerance. Proc Natl Acad Sci U S A. 2015 Jan 06; 112(1):E39-48. PMID: 25535377.
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    16. Kedl RM, Wysocki LJ, Janssen WJ, Born WK, Rosenbaum MD, Granowski J, Kench JA, Fong DL, Switzer LA, Cruse M, Huang H, Jakubzick CV, Kosmider B, Takeda K, Stranova TJ, Klumm RC, Delgado C, Tummala S, De Langhe S, Cambier J, Haskins K, Lenz LL, Curran-Everett D. General parity between trio and pairwise breeding of laboratory mice in static caging. J Immunol. 2014 Nov 15; 193(10):4757-60. PMID: 25381356.
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    17. Huang H, Li Y. Mechanisms controlling mast cell and basophil lineage decisions. Curr Allergy Asthma Rep. 2014 Sep; 14(9):457. PMID: 25086577.
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    18. Milgrom H, Huang H. Allergic disorders at a venerable age: a mini-review. Gerontology. 2014; 60(2):99-107. PMID: 24334920.
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    19. Chen Z, Wang S, Erekosima N, Li Y, Hong J, Qi X, Merkel P, Nagabhushanam V, Choo E, Katial R, Alam R, Trikha A, Chu HW, Zhuang Y, Jin M, Bai C, Huang H. IL-4 confers resistance to IL-27-mediated suppression on CD4+ T cells by impairing signal transducer and activator of transcription 1 signaling. J Allergy Clin Immunol. 2013 Oct; 132(4):912-21.e1-5. PMID: 23958647.
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    20. Qi X, Hong J, Chaves L, Zhuang Y, Chen Y, Wang D, Chabon J, Graham B, Ohmori K, Li Y, Huang H. Antagonistic regulation by the transcription factors C/EBPa and MITF specifies basophil and mast cell fates. Immunity. 2013 Jul 25; 39(1):97-110. PMID: 23871207.
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    21. Nishida J, Li Y, Zhuang Y, Huang Z, Huang H. IFN-? suppresses permissive chromatin remodeling in the regulatory region of the Il4 gene. Cytokine. 2013 Apr; 62(1):91-5. PMID: 23490416.
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    22. Huang H, Qi X. Differentiation of innate type-2 effector cells. Immunol Res. 2013 Mar; 55(1-3):173-7. PMID: 22945806.
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    23. Huang H, Li Y, Qi X. Cytokine signaling in the differentiation of innate effector cells. JAKSTAT. 2013 Jan 01; 2(1):e23531. PMID: 24058796.
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    24. Thaikoottathil JV, Martin RJ, Di PY, Minor M, Case S, Zhang B, Zhang G, Huang H, Chu HW. SPLUNC1 deficiency enhances airway eosinophilic inflammation in mice. Am J Respir Cell Mol Biol. 2012 Aug; 47(2):253-60. PMID: 22499853.
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    25. Goplen N, Karim Z, Guo L, Zhuang Y, Huang H, Gorska MM, Gelfand E, Pag?s G, Pouyss?gur J, Alam R. ERK1 is important for Th2 differentiation and development of experimental asthma. FASEB J. 2012 May; 26(5):1934-45. PMID: 22262639.
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    26. Huang H. Suppressing allergic immune responses. Front Biosci (Elite Ed). 2011 06 01; 3(3):864-70. PMID: 21622097.
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    27. Qi X, Nishida J, Chaves L, Ohmori K, Huang H. CCAAT/enhancer-binding protein alpha (C/EBPalpha) is critical for interleukin-4 expression in response to FcepsilonRI receptor cross-linking. J Biol Chem. 2011 May 06; 286(18):16063-73. PMID: 21454593.
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    28. Bai X, Kim SH, Azam T, McGibney MT, Huang H, Dinarello CA, Chan ED. IL-32 is a host protective cytokine against Mycobacterium tuberculosis in differentiated THP-1 human macrophages. J Immunol. 2010 Apr 01; 184(7):3830-40. PMID: 20190143.
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    29. Born WK, Huang Y, Jin N, Huang H, O'Brien RL. Balanced approach of gammadelta T cells to type 2 immunity. Immunol Cell Biol. 2010 Mar-Apr; 88(3):269-74. PMID: 20101253.
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    30. Zhuang Y, Huang Z, Nishida J, Brown M, Zhang L, Huang H. A continuous T-bet expression is required to silence the interleukin-4-producing potential in T helper type 1 cells. Immunology. 2009 Sep; 128(1):34-42. PMID: 19689734.
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    31. Huang Y, Jin N, Roark CL, Aydintug MK, Wands JM, Huang H, O'Brien RL, Born WK. The influence of IgE-enhancing and IgE-suppressive gammadelta T cells changes with exposure to inhaled ovalbumin. J Immunol. 2009 Jul 15; 183(2):849-55. PMID: 19542369.
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    32. Ohmori K, Luo Y, Jia Y, Nishida J, Wang Z, Bunting KD, Wang D, Huang H. IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increasing the number of basophil/mast cell progenitors in the spleen. J Immunol. 2009 Mar 01; 182(5):2835-41. PMID: 19234178.
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