Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution
Menu

Contact Us
If you have any questions or feedback please contact us.

Edward David Chan

TitlePrincipal Investigator
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone303/315-7767

    Collapse Research 
    Collapse research activities and funding
    I01BX005651     (CHAN, EDWARD D)Jul 1, 2023 - Jun 30, 2027
    NIH
    Establishing the Therapeutic Efficacy of Alpha-1-Antitrypsin and Enoxaparin Against COVID-19
    Role: Principal Investigator
    I01CX001452     (CHAN, EDWARD D)Oct 1, 2017 - Sep 30, 2021
    NIH
    How Does Nicotine Impair Macrophage Killing of Mycobacterium Tuberculosis? 
    Role: Principal Investigator
    R21AI121605     (CHAN, EDWARD D)Jun 14, 2016 - May 31, 2019
    NIH
    The role of T regulatory cells in cigarette smoke-induced susceptibility to tuberculosis
    Role: Principal Investigator
    I01BX001028     (CHAN, EDWARD D)Oct 1, 2011 - Sep 30, 2015
    NIH
    Mechanistic study of the host defense functions of IL-32 in tuberculosis
    Role: Principal Investigator
    R01HL066112     (CHAN, EDWARD D)Jul 15, 2001 - Nov 30, 2007
    NIH
    Host defense functions of M. tuberculosis lipoglycan
    Role: Principal Investigator
    K08HL003625     (CHAN, EDWARD D)Jan 1, 1997 - Dec 31, 2001
    NIH
    REGULATION OF INSULIN LIKE GROWTH FACTOR I
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Chan ED. Identification of Alpha-1 Antitrypsin-Deficient Subjects with Normal Spirometry Who May Benefit from Alpha-1 Antitrypsin Replacement. Am J Respir Crit Care Med. 2024 04 15; 209(8):1033-1034. PMID: 38237158.
      View in: PubMed
    2. Dawrs SN, Virdi R, Norton GJ, Elias T, Hasan NA, Robinson S, Matriz J, Epperson LE, Glickman CM, Beagle S, Crooks JL, Nelson ST, Chan ED, Damby DE, Strong M, Honda JR. Hawaiian Volcanic Ash, an Airborne Fomite for Nontuberculous Mycobacteria. Geohealth. 2024 Jan; 8(1):e2023GH000889. PMID: 38161597.
      View in: PubMed
    3. Bai X, Verma D, Garcia C, Musheyev A, Kim K, Fornis L, Griffith DE, Li L, Whittel N, Gadwa J, Ohanjanyan T, Eggleston MJ, Galvan M, Freed BM, Ordway D, Chan ED. Ex vivo and in vivo evidence that cigarette smoke-exposed T regulatory cells impair host immunity against Mycobacterium tuberculosis. Front Cell Infect Microbiol. 2023; 13:1216492. PMID: 37965256.
      View in: PubMed
    4. Hendrix J, Epperson LE, Tong EI, Chan YL, Hasan NA, Dawrs SN, Norton GJ, Virdi R, Crooks JL, Chan ED, Honda JR, Strong M. Complete genome assembly of Hawai'i environmental nontuberculous mycobacteria reveals unexpected co-isolation with methylobacteria. PLoS One. 2023; 18(9):e0291072. PMID: 37703253.
      View in: PubMed
    5. Dawrs SN, Virdi R, Islam MN, Hasan NA, Norton GJ, Crooks JL, Parr J, Heinz D, Cool CD, Belisle JT, Chan ED, Honda JR. Immunological and metabolic characterization of environmental Mycobacterium chimaera infection in a murine model. Microbes Infect. 2023 Nov-Dec; 25(8):105184. PMID: 37453489.
      View in: PubMed
    6. Bai X, Schountz T, Buckle AM, Talbert JL, Sandhaus RA, Chan ED. Alpha-1-antitrypsin antagonizes COVID-19: a review of the epidemiology, molecular mechanisms, and clinical evidence. Biochem Soc Trans. 2023 06 28; 51(3):1361-1375. PMID: 37294003.
      View in: PubMed
    7. Dow CT, Lin NW, Chan ED. Sarcoidosis, Mycobacterium paratuberculosis and Noncaseating Granulomas: Who Moved My Cheese. Microorganisms. 2023 Mar 24; 11(4). PMID: 37110254.
      View in: PubMed
    8. Peters J, Maselli DJ, Mangat M, Coalson JJ, Hinojosa C, Giavedoni L, Brown-Elliott BA, Chan E, Griffith D. A marmoset model for Mycobacterium avium complex pulmonary disease. PLoS One. 2023; 18(3):e0260563. PMID: 36893126.
      View in: PubMed
    9. Rockstrom M, Lutz R, Dickeson K, O'Rorke EV, Narita M, Amram O, Chan ED. Fulminant pulmonary tuberculosis in a previously healthy young woman from the Marshall Islands: Potential risk factors. J Clin Tuberc Other Mycobact Dis. 2023 May; 31:100351. PMID: 36923241.
      View in: PubMed
    10. Arguinchona LM, Zagona-Prizio C, Joyce ME, Chan ED, Maloney JP. Microvascular significance of TGF-? axis activation in COVID-19. Front Cardiovasc Med. 2022; 9:1054690. PMID: 36684608.
      View in: PubMed
    11. Campbell JR, Chan ED, Falzon D, Trajman A, Keshavjee S, Leung CC, Miller AC, Monedero-Recuero I, Rodrigues DS, Seo H, Baghaei P, Udwadia Z, Viiklepp P, Bastos M, Menzies D. Low Body Mass Index at Treatment Initiation and Rifampicin-Resistant Tuberculosis Treatment Outcomes: An Individual Participant Data Meta-Analysis. Clin Infect Dis. 2022 12 19; 75(12):2201-2210. PMID: 35476134.
      View in: PubMed
    12. Lu M, Chen W, Lei Z, Dai S, Hou C, Du S, Geake J, Bhurayanontachai R, Karamchand S, Chan ED, Jin Q, Li H. Image-guided percutaneous biopsy and pathological diagnosis in atypical tuberculous spondylitis: a case series and clinical outcomes. Ann Transl Med. 2022 Oct; 10(20):1140. PMID: 36388828.
      View in: PubMed
    13. Bai X, Bai A, Tomasicchio M, Hagman JR, Buckle AM, Gupta A, Kadiyala V, Bevers S, Serban KA, Kim K, Feng Z, Spendier K, Hagen G, Fornis L, Griffith DE, Dzieciatkowska M, Sandhaus RA, Gerber AN, Chan ED. a1-Antitrypsin Binds to the Glucocorticoid Receptor with Anti-Inflammatory and Antimycobacterial Significance in Macrophages. J Immunol. 2022 11 01; 209(9):1746-1759. PMID: 36162872.
      View in: PubMed
    14. Youssefnia A, Pierre A, Hoder JM, MacDonald M, Shaffer MJB, Friedman J, Mehler PS, Bontempo A, da Silva FCN, Chan ED. Ancillary treatment of patients with lung disease due to non-tuberculous mycobacteria: a narrative review. J Thorac Dis. 2022 Sep; 14(9):3575-3597. PMID: 36245600.
      View in: PubMed
    15. Abdelaal HFM, Chan ED, Young L, Baldwin SL, Coler RN. Mycobacterium abscessus: It's Complex. Microorganisms. 2022 Jul 19; 10(7). PMID: 35889173.
      View in: PubMed
    16. Byrd TF, Chan ED. Editorial: Mycobacterium abscessus; The Paradox of Low Pathogenicity and High Virulence. Front Microbiol. 2022; 13:943694. PMID: 35756056.
      View in: PubMed
    17. Bai X, Buckle AM, Vladar EK, Janoff EN, Khare R, Ordway D, Beckham D, Fornis LB, Majluf-Cruz A, Fugit RV, Freed BM, Kim S, Sandhaus RA, Chan ED. Author Correction: Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19. Sci Rep. 2022 Apr 19; 12(1):6466. PMID: 35440617.
      View in: PubMed
    18. Parsons AW, Dawrs SN, Nelson ST, Norton GJ, Virdi R, Hasan NA, Epperson LE, Holst B, Chan ED, Leos-Barajas V, Reich BJ, Crooks JL, Strong M, Pacifici K, Honda JR. Soil Properties and Moisture Synergistically Influence Nontuberculous Mycobacterial Prevalence in Natural Environments of Hawai'i. Appl Environ Microbiol. 2022 05 10; 88(9):e0001822. PMID: 35435715.
      View in: PubMed
    19. Schenkel AR, Mitchell JD, Cool CD, Bai X, Groshong S, Koelsch T, Verma D, Ordway D, Chan ED. Characterization of Immune Cells From the Lungs of Patients With Chronic Non-Tuberculous Mycobacteria or Pseudomonas aeruginosa Infection. Immune Netw. 2022 Jun; 22(3):e27. PMID: 35799709.
      View in: PubMed
    20. Bai X, Buckle AM, Vladar EK, Janoff EN, Khare R, Ordway D, Beckham D, Fornis LB, Majluf-Cruz A, Fugit RV, Freed BM, Kim S, Sandhaus RA, Chan ED. Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19. Sci Rep. 2022 03 25; 12(1):5207. PMID: 35338216.
      View in: PubMed
    21. Dow CT, Greenblatt CL, Chan ED, Dow JF. Evaluation of BCG Vaccination and Plasma Amyloid: A Prospective, Pilot Study with Implications for Alzheimer's Disease. Microorganisms. 2022 Feb 12; 10(2). PMID: 35208878.
      View in: PubMed
    22. Choi S, Potts KJ, Althoff MD, Jimenez G, Bai X, Calhoun KM, Cool CD, Chan ED. Histopathologic Analysis of Surgically Resected Lungs of Patients with Non-tuberculous Mycobacterial Lung Disease: a Retrospective and Hypothesis-generating Study. Yale J Biol Med. 2021 12; 94(4):527-535. PMID: 34970090.
      View in: PubMed
    23. Johara FT, Benedetti A, Platt R, Menzies D, Viiklepp P, Schaaf S, Chan E. Evaluating the performance of propensity score matching based approaches in individual patient data meta-analysis. BMC Med Res Methodol. 2021 11 23; 21(1):257. PMID: 34814845.
      View in: PubMed
    24. Tun MH, Borg B, Godfrey M, Hadley-Miller N, Chan ED. Respiratory manifestations of Marfan syndrome: a narrative review. J Thorac Dis. 2021 Oct; 13(10):6012-6025. PMID: 34795948.
      View in: PubMed
    25. Chen J, Xie F, Zheng X, Li Y, Liu S, Ma KC, Goto T, M?ller T, Chan ED, Sun J. Mobile 3-dimensional (3D) C-arm system-assisted transbronchial biopsy and ablation for ground-glass opacity pulmonary nodules: a case report. Transl Lung Cancer Res. 2021 Jul; 10(7):3312-3319. PMID: 34430367.
      View in: PubMed
    26. Dempers L, Lane T, Moubry RM, Chan ED. Taking Extra Steps in Evaluating a Lung Nodule. Ann Am Thorac Soc. 2021 06; 18(6):1063-1065. PMID: 34076558.
      View in: PubMed
    27. Ha DM, Zeng C, Chan ED, Gray M, Mazzone PJ, Samet JM, Steiner JF. Association of Exercise Behavior with Overall Survival in Stage I-IIIA Lung Cancer. Ann Am Thorac Soc. 2021 06; 18(6):1034-1042. PMID: 33326358.
      View in: PubMed
    28. Chan ED, Cota-Gomez A, Podell B. Adding Another Piece to the Puzzle of Why NTM Infections Are Relatively Uncommon despite Their Ubiquitous Nature. mBio. 2021 04 20; 12(2). PMID: 33879587.
      View in: PubMed
    29. Knitz MW, Bickett TE, Darragh LB, Oweida AJ, Bhatia S, Van Court B, Bhuvane S, Piper M, Gadwa J, Mueller AC, Nguyen D, Nangia V, Osborne DG, Bai X, Ferrara SE, Boss MK, Goodspeed A, Burchill MA, Tamburini BAJ, Chan ED, Pickering CR, Clambey ET, Karam SD. Targeting resistance to radiation-immunotherapy in cold HNSCCs by modulating the Treg-dendritic cell axis. J Immunother Cancer. 2021 04; 9(4). PMID: 33883256.
      View in: PubMed
    30. Nelson ST, Robinson S, Rey K, Brown L, Jones N, Dawrs SN, Virdi R, Norton GJ, Epperson LE, Hasan NA, Chan ED, Strong M, Honda JR. Exposure Pathways of Nontuberculous Mycobacteria Through Soil, Streams, and Groundwater, Hawai'i, USA. Geohealth. 2021 Apr; 5(4):e2020GH000350. PMID: 33855248.
      View in: PubMed
    31. Verma D, Chan ED, Ordway DJ. The double-edged sword of Tregs in M tuberculosis, M avium, and M absessus infection. Immunol Rev. 2021 05; 301(1):48-61. PMID: 33713043.
      View in: PubMed
    32. Chan ED, Majluf-Cruz A. Is the Angioedema Associated with COVID-19 a Real Entity, a Mimic, or Both? Am J Respir Crit Care Med. 2021 03 01; 203(5):645-646. PMID: 33357169.
      View in: PubMed
    33. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-G?mez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, ?lvarez ?MC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Ant?n Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Ara?jo WL, Araya J, Arden C, Ar?valo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnaun?-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, ?valos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, B?nr?ti ?, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Baril? D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touz? N, Bellarosa C, Belleudi F, Bell? P?rez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Bur?n MI, Bustos V, B?ttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cair? M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, Camuzard O, Cancino J, Candido de Almeida D, Canesi L, Caniggia I, Canonico B, Cant? C, Cao B, Caraglia M, Caram?s B, Carchman EH, Cardenal-Mu?oz E, Cardenas C, Cardenas L, Cardoso SM, Carew JS, Carle GF, Carleton G, Carloni S, Carmona-Gutierrez D, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382. PMID: 33634751.
      View in: PubMed
    34. Dow CT, Chan ED. What is the evidence that mycobacteria are associated with the pathogenesis of Sjogren's syndrome? J Transl Autoimmun. 2021; 4:100085. PMID: 33665595.
      View in: PubMed
    35. Yiang GT, Tzeng IS, Shui HA, Wu MY, Peng MY, Chan CY, Chan ED, Wu YK, Lan CC, Yang MC, Huang KL, Wu CW, Chang CH, Su WL. Early Screening of Risk for Multidrug-Resistant Organisms in the Emergency Department in Patients With Pneumonia and Early Septic Shock: Single-Center, Retrospective Cohort Study. Shock. 2021 02 01; 55(2):198-209. PMID: 32694392.
      View in: PubMed
    36. Grayeb DE, Chan ED, Swanson LM, Gibson DG, Mehler PS. Nontuberculous mycobacterial lung infections in patients with eating disorders: plausible mechanistic links in a case series. AME Case Rep. 2021; 5:9. PMID: 33634249.
      View in: PubMed
    37. Ha DM, Prochazka AV, Bekelman DB, Stevens-Lapsley JE, Chan ED, Keith RL. Association of Leisure-Time Physical Activity With Health-Related Quality of Life Among US Lung Cancer Survivors. JNCI Cancer Spectr. 2021 02; 5(1). PMID: 35075444.
      View in: PubMed
    38. Virdi R, Lowe ME, Norton GJ, Dawrs SN, Hasan NA, Epperson LE, Glickman CM, Chan ED, Strong M, Crooks JL, Honda JR. Lower Recovery of Nontuberculous Mycobacteria from Outdoor Hawai'i Environmental Water Biofilms Compared to Indoor Samples. Microorganisms. 2021 Jan 22; 9(2). PMID: 33499212.
      View in: PubMed
    39. Chan ED, Sharma V. Does Hypoxia Itself Beget Worsening Hypoxemia in COVID-19? Mayo Clin Proc. 2021 03; 96(3):824-825. PMID: 33673937.
      View in: PubMed
    40. Hasan NA, Norton GJ, Virdi R, Epperson LE, Vang CK, Hellbusch B, Bai X, Chan ED, Strong M, Honda JR. Measurable genomic changes in Mycobacterium avium subsp. hominissuis after long-term adaptation in Acanthamoeba lenticulata and reduced persistence in macrophages. J Bacteriol. 2021 03 15; 203(6). PMID: 33431432.
      View in: PubMed
    41. Weingart MF, Li Q, Choi S, Maleki-Fischbach M, Kwon YS, Koelsch T, Dow CT, Truong TQ, Chan ED. Analysis of Non-TB Mycobacterial Lung Disease in Patients With Primary Sj?gren's Syndrome at a Referral Center. Chest. 2021 06; 159(6):2218-2221. PMID: 33440182.
      View in: PubMed
    42. Odackal J, Milinic T, Amass T, Chan ED, Hua J, Krefft S. A 28-Year-Old Man With Chest Pain, Shortness of Breath, and Hemoptysis After Recovery From Coronavirus Disease 2019 Pneumonia. Chest. 2021 01; 159(1):e35-e38. PMID: 33422238.
      View in: PubMed
    43. Chan ED, Bai X. Further evidence that cigarette smoke and nicotine compromise host immunity against tuberculosis (invited editorial). Tuberculosis (Edinb). 2021 03; 127:102035. PMID: 33317928.
      View in: PubMed
    44. Verma D, Chan ED, Ordway DJ. Non-Tuberculous Mycobacteria Interference with BCG-Current Controversies and Future Directions. Vaccines (Basel). 2020 Nov 16; 8(4). PMID: 33207695.
      View in: PubMed
    45. Bai X, Hippensteel J, Leavitt A, Maloney JP, Beckham D, Garcia C, Li Q, Freed BM, Ordway D, Sandhaus RA, Chan ED. Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19. Med Hypotheses. 2021 Jan; 146:110394. PMID: 33239231.
      View in: PubMed
    46. Kwak N, Winters N, Campbell JR, Chan ED, Gegia M, Lange C, Lee M, Milanov V, Menzies D, Yim JJ. Changes in treatment for multidrug-resistant tuberculosis according to national income. Eur Respir J. 2020 11; 56(5). PMID: 32586878.
      View in: PubMed
    47. Kim S, Lee JH, Lee S, Shim S, Nguyen TT, Hwang J, Kim H, Choi YO, Hong J, Bae S, Jhun H, Yum H, Lee Y, Chan ED, Yu L, Azam T, Kim YD, Yeom SC, Yoo KH, Kang LW, Shin KC, Kim S. The Progression of SARS Coronavirus 2 (SARS-CoV2): Mutation in the Receptor Binding Domain of Spike Gene. Immune Netw. 2020 Oct; 20(5):e41. PMID: 33163249.
      View in: PubMed
    48. Glickman CM, Virdi R, Hasan NA, Epperson LE, Brown L, Dawrs SN, Crooks JL, Chan ED, Strong M, Nelson ST, Honda JR. Assessment of Soil Features on the Growth of Environmental Nontuberculous Mycobacterial Isolates from Hawai'i. Appl Environ Microbiol. 2020 10 15; 86(21). PMID: 32859599.
      View in: PubMed
    49. Honda JR, Chan YL, Tong EI, Kawatachi M, Virdi R, Norton GJ, Dawrs SN, Hasan NA, Epperson LE, Crooks JT, Chan ED, Strong M. Inaugural nontuberculous mycobacterial lung disease education and research conference, Honolulu, Hawai'i, February 1-2, 2020. Microbes Infect. 2021 Jan-Feb; 23(1):104763. PMID: 33035706.
      View in: PubMed
    50. Davidson KR, Ha DM, Schwarz MI, Chan ED. Bronchoalveolar lavage as a diagnostic procedure: a review of known cellular and molecular findings in various lung diseases. J Thorac Dis. 2020 Sep; 12(9):4991-5019. PMID: 33145073.
      View in: PubMed
    51. Moon P, Guillaumin E, Chan ED. Non-tuberculous mycobacterial lung disease due to multiple "minor" risk factors: an illustrative case and a review of these "lesser elements". J Thorac Dis. 2020 Sep; 12(9):4960-4972. PMID: 33145070.
      View in: PubMed
    52. Li T, Taba ST, Khong PL, Tan TX, Trieu PDY, Chan E, Suleiman ME, Li Y, Brennan P, Lewis S. Reading High Breast Density Mammograms: Differences in Diagnostic Performance between Radiologists from Hong Kong SAR/Guangdong Province in China and Australia. Asian Pac J Cancer Prev. 2020 Sep 01; 21(9):2623-2629. PMID: 32986361.
      View in: PubMed
    53. King M, Hurley H, Davidson KR, Dempsey EC, Barron MA, Chan ED, Frey A. The Link between Fusobacteria and Colon Cancer: a Fulminant Example and Review of the Evidence. Immune Netw. 2020 Aug; 20(4):e30. PMID: 32895617.
      View in: PubMed
    54. Dawrs SN, Kautz M, Chan ED, Honda JR. Mycobacteriumabscessus and Gastroesophageal Reflux: An In Vitro Study. Am J Respir Crit Care Med. 2020 08 01; 202(3):466-469. PMID: 32298605.
      View in: PubMed
    55. Chan ED, Majluf-Cruz A. Hereditary Angioedema. N Engl J Med. 2020 07 23; 383(4):e20. PMID: 32706544.
      View in: PubMed
    56. Chan ED, Verma D, Ordway DJ. Animal Models of Mycobacteria Infection. Curr Protoc Immunol. 2020 06; 129(1):e98. PMID: 32497414.
      View in: PubMed
    57. Chan ED. Are there common threads in the susceptibility to cancer and tuberculosis? J Thorac Dis. 2020 May; 12(5):1776-1780. PMID: 32642083.
      View in: PubMed
    58. Honda JR, Hess T, Carlson R, Kandasamy P, Nieto Ramirez LM, Norton GJ, Virdi R, Islam MN, Mehaffy C, Hasan NA, Epperson LE, Hesser D, Alper S, Strong M, Flores SC, Voelker DR, Dobos KM, Chan ED. Nontuberculous Mycobacteria Show Differential Infectivity and Use Phospholipids to Antagonize LL-37. Am J Respir Cell Mol Biol. 2020 03; 62(3):354-363. PMID: 31545652.
      View in: PubMed
    59. Feng Z, Bai X, Wang T, Garcia C, Bai A, Li L, Honda JR, Nie X, Chan ED. Differential Responses by Human Macrophages to Infection With Mycobacterium tuberculosis and Non-tuberculous Mycobacteria. Front Microbiol. 2020; 11:116. PMID: 32117140.
      View in: PubMed
    60. Choi S, Richards JC, Chan ED. Can physics principles help explain why non-tuberculous mycobacterial lung disease is more severe in the right middle lobe and lingula? J Thorac Dis. 2019 Nov; 11(11):4847-4854. PMID: 31903275.
      View in: PubMed
    61. Chan ED, Chan MM, Chan MM, Marik PE. Use of glucocorticoids in the critical care setting: Science and clinical evidence. Pharmacol Ther. 2020 02; 206:107428. PMID: 31626870.
      View in: PubMed
    62. Damen MSMA, Ballak D, Sapinsley Z, Bai X, Chan ED, Seals DR, Popa CD, Joosten LAB. Transgenic mice expressing human IL-32 develop adipokine profiles resembling those of obesity-induced metabolic changes. Cytokine. 2020 01; 125:154793. PMID: 31398626.
      View in: PubMed
    63. Bai X, Bai A, Honda JR, Eichstaedt C, Musheyev A, Feng Z, Huitt G, Harbeck R, Kosmider B, Sandhaus RA, Chan ED. Alpha-1-Antitrypsin Enhances Primary Human Macrophage Immunity Against Non-tuberculous Mycobacteria. Front Immunol. 2019; 10:1417. PMID: 31293581.
      View in: PubMed
    64. Marras TK, Mirsaeidi M, Vinnard C, Chan ED, Eagle G, Zhang R, Wang P, Zhang Q. Guidelines-based treatment associated with improved economic outcomes in nontuberculous mycobacterial lung disease. J Med Econ. 2019 Nov; 22(11):1126-1133. PMID: 31094592.
      View in: PubMed
    65. Kim EW, De Leon A, Jiang Z, Radu RA, Martineau AR, Chan ED, Bai X, Su WL, Montoya DJ, Modlin RL, Liu PT. Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against Mycobacterium tuberculosis. mSphere. 2019 06 05; 4(3). PMID: 31167948.
      View in: PubMed
    66. Verma D, Stapleton M, Gadwa J, Vongtongsalee K, Schenkel AR, Chan ED, Ordway D. Mycobacterium avium Infection in a C3HeB/FeJ Mouse Model. Front Microbiol. 2019; 10:693. PMID: 31001241.
      View in: PubMed
    67. Tran T, Bonham AJ, Chan ED, Honda JR. A paucity of knowledge regarding nontuberculous mycobacterial lipids compared to the tubercle bacillus. Tuberculosis (Edinb). 2019 03; 115:96-107. PMID: 30948183.
      View in: PubMed
    68. Gebert MJ, Delgado-Baquerizo M, Oliverio AM, Webster TM, Nichols LM, Honda JR, Chan ED, Adjemian J, Dunn RR, Fierer N. Ecological Analyses of Mycobacteria in Showerhead Biofilms and Their Relevance to Human Health. mBio. 2018 10 30; 9(5). PMID: 30377276.
      View in: PubMed
    69. Ahmad N, Ahuja SD, Akkerman OW, Alffenaar JC, Anderson LF, Baghaei P, Bang D, Barry PM, Bastos ML, Behera D, Benedetti A, Bisson GP, Boeree MJ, Bonnet M, Brode SK, Brust JCM, Cai Y, Caumes E, Cegielski JP, Centis R, Chan PC, Chan ED, Chang KC, Charles M, Cirule A, Dalcolmo MP, D'Ambrosio L, de Vries G, Dheda K, Esmail A, Flood J, Fox GJ, Fr?chet-Jachym M, Fregona G, Gayoso R, Gegia M, Gler MT, Gu S, Guglielmetti L, Holtz TH, Hughes J, Isaakidis P, Jarlsberg L, Kempker RR, Keshavjee S, Khan FA, Kipiani M, Koenig SP, Koh WJ, Kritski A, Kuksa L, Kvasnovsky CL, Kwak N, Lan Z, Lange C, Laniado-Labor?n R, Lee M, Leimane V, Leung CC, Leung EC, Li PZ, Lowenthal P, Maciel EL, Marks SM, Mase S, Mbuagbaw L, Migliori GB, Milanov V, Miller AC, Mitnick CD, Modongo C, Mohr E, Monedero I, Nahid P, Ndjeka N, O'Donnell MR, Padayatchi N, Palmero D, Pape JW, Podewils LJ, Reynolds I, Riekstina V, Robert J, Rodriguez M, Seaworth B, Seung KJ, Schnippel K, Shim TS, Singla R, Smith SE, Sotgiu G, Sukhbaatar G, Tabarsi P, Tiberi S, Trajman A, Trieu L, Udwadia ZF, van der Werf TS, Veziris N, Viiklepp P, Vilbrun SC, Walsh K, Westenhouse J, Yew WW, Yim JJ, Zetola NM, Zignol M, Menzies D. Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis. Lancet. 2018 09 08; 392(10150):821-834. PMID: 30215381.
      View in: PubMed
    70. Ketai L, Currie BJ, Holt MR, Chan ED. Radiology of Chronic Cavitary Infections. J Thorac Imaging. 2018 Sep; 33(5):334-343. PMID: 30048346.
      View in: PubMed
    71. Holt MR, Chan ED. Chronic Cavitary Infections Other than Tuberculosis: Clinical Aspects. J Thorac Imaging. 2018 Sep; 33(5):322-333. PMID: 30036298.
      View in: PubMed
    72. Honda JR, Virdi R, Chan ED. Global Environmental Nontuberculous Mycobacteria and Their Contemporaneous Man-Made and Natural Niches. Front Microbiol. 2018; 9:2029. PMID: 30214436.
      View in: PubMed
    73. Chan ED. Thin body habitus is a risk factor for active pulmonary tuberculosis, but not for infection. Int J Tuberc Lung Dis. 2018 08 01; 22(8):967-968. PMID: 29991410.
      View in: PubMed
    74. Harausz EP, Garcia-Prats AJ, Law S, Schaaf HS, Kredo T, Seddon JA, Menzies D, Turkova A, Achar J, Amanullah F, Barry P, Becerra M, Chan ED, Chan PC, Ioana Chiotan D, Crossa A, Drobac PC, Fairlie L, Falzon D, Flood J, Gegia M, Hicks RM, Isaakidis P, Kadri SM, Kampmann B, Madhi SA, Marais E, Mariandyshev A, M?ndez-Echevarr?a A, Moore BK, Nargiza P, Ozere I, Padayatchi N, Ur-Rehman S, Rybak N, Santiago-Garcia B, Shah NS, Sharma S, Shim TS, Skrahina A, Soriano-Arandes A, van den Boom M, van der Werf MJ, van der Werf TS, Williams B, Yablokova E, Yim JJ, Furin J, Hesseling AC. Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis. PLoS Med. 2018 07; 15(7):e1002591. PMID: 29995958.
      View in: PubMed
    75. Chan ED. Reduced IFN-? in Patients with Pulmonary Nontuberculous Mycobacterial Disease: Potentially Multiple Causes. Am J Respir Cell Mol Biol. 2018 07; 59(1):130-131. PMID: 29957052.
      View in: PubMed
    76. Bai X, Aerts SL, Verma D, Ordway DJ, Chan ED. Epidemiologic Evidence of and Potential Mechanisms by Which Second-Hand Smoke Causes Predisposition to Latent and Active Tuberculosis. Immune Netw. 2018 Jun; 18(3):e22. PMID: 29984040.
      View in: PubMed
    77. Honda JR, Alper S, Bai X, Chan ED. Acquired and genetic host susceptibility factors and microbial pathogenic factors that predispose to nontuberculous mycobacterial infections. Curr Opin Immunol. 2018 10; 54:66-73. PMID: 29936307.
      View in: PubMed
    78. Gomes RS, Silva MVT, Dos Santos JC, van Linge C, Reis JM, Teixeira MM, Pinto SA, Dorta ML, Bai X, Chan ED, Dinarello CA, Oliveira MAP, Joosten LAB, Ribeiro-Dias F. Human Interleukin-32? Plays a Protective Role in an Experimental Model of Visceral Leishmaniasis in Mice. Infect Immun. 2018 05; 86(5). PMID: 29483288.
      View in: PubMed
    79. Brown JK, Singh K, Dumitru R, Chan E, Kim MP. The Benefits of Enhanced Recovery After Surgery Programs and Their Application in Cardiothoracic Surgery. Methodist Debakey Cardiovasc J. 2018 Apr-Jun; 14(2):77-88. PMID: 29977464.
      View in: PubMed
    80. Honda JR, Bai X, Chan ED. Elucidating the Pathogenesis of Nontuberculous Mycobacterial Lung Disease: Lesson from the Six Blind Men and the Elephant. Am J Respir Cell Mol Biol. 2018 02; 58(2):142-143. PMID: 29388833.
      View in: PubMed
    81. Malcolm KC, Caceres SM, Honda JR, Davidson RM, Epperson LE, Strong M, Chan ED, Nick JA. Mycobacterium abscessus Displays Fitness for Fomite Transmission. Appl Environ Microbiol. 2017 10 01; 83(19). PMID: 28754702.
      View in: PubMed
    82. Bai X, Stitzel JA, Bai A, Zambrano CA, Phillips M, Marrack P, Chan ED. Nicotine Impairs Macrophage Control of Mycobacterium tuberculosis. Am J Respir Cell Mol Biol. 2017 09; 57(3):324-333. PMID: 28398760.
      View in: PubMed
    83. Zhao X, Epperson LE, Hasan NA, Honda JR, Chan ED, Strong M, Walter ND, Davidson RM. Complete Genome Sequence of Mycobacterium avium subsp. hominissuis Strain H87 Isolated from an Indoor Water Sample. Genome Announc. 2017 Apr 20; 5(16). PMID: 28428297.
      View in: PubMed
    84. Lee S, Choi DK, Kwak A, Kim S, Nguyen TT, Gil G, Kim E, Yoo KH, Kim IA, Lee Y, Jhun H, Chan ED, Bai X, Kim H, Kim YS, Kim S. IL-32-induced Inflammatory Cytokines Are Selectively Suppressed by a1-antitrypsin in Mouse Bone Marrow Cells. Immune Netw. 2017 Apr; 17(2):116-120. PMID: 28458623.
      View in: PubMed
    85. Farabaugh KT, Majumder M, Guan BJ, Jobava R, Wu J, Krokowski D, Gao XH, Schuster A, Longworth M, Chan ED, Bianchi M, Dey M, Koromilas AE, Ramakrishnan P, Hatzoglou M. Protein Kinase R Mediates the Inflammatory Response Induced by Hyperosmotic Stress. Mol Cell Biol. 2017 02 15; 37(4). PMID: 27920257.
      View in: PubMed
    86. Williams JG, Phan H, Winston HR, Fugit RV, Graney B, Jamroz B, English B, Chan ED. A 27-Year-Old Man With Acute Severe Low Back Pain and Bilateral Leg Swelling That Prompted Renting a Wheelchair for Mobility. Chest. 2017 Feb; 151(2):e35-e39. PMID: 28183502.
      View in: PubMed
    87. Becker KL, Arts P, Jaeger M, Plantinga TS, Gilissen C, van Laarhoven A, van Ingen J, Veltman JA, Joosten LA, Hoischen A, Netea MG, Iseman MD, Chan ED, van de Veerdonk FL. MST1R mutation as a genetic cause of Lady Windermere syndrome. Eur Respir J. 2017 01; 49(1). PMID: 28100548.
      View in: PubMed
    88. Honda JR, Hasan NA, Davidson RM, Williams MD, Epperson LE, Reynolds PR, Smith T, Iakhiaeva E, Bankowski MJ, Wallace RJ, Chan ED, Falkinham JO, Strong M. Correction: Environmental Nontuberculous Mycobacteria in the Hawaiian Islands. PLoS Negl Trop Dis. 2016 Dec; 10(12):e0005200. PMID: 27911953.
      View in: PubMed
    89. Hasan NA, Honda JR, Davidson RM, Epperson LE, Bankowski MJ, Chan ED, Strong M. Complete Genome Sequence of Mycobacterium chimaera Strain AH16. Genome Announc. 2016 Nov 23; 4(6). PMID: 27881537.
      View in: PubMed
    90. Honda JR, Hasan NA, Davidson RM, Williams MD, Epperson LE, Reynolds PR, Smith T, Iakhiaeva E, Bankowski MJ, Wallace RJ, Chan ED, Falkinham JO, Strong M. Environmental Nontuberculous Mycobacteria in the Hawaiian Islands. PLoS Negl Trop Dis. 2016 Oct; 10(10):e0005068. PMID: 27780201.
      View in: PubMed
    91. Philley JV, DeGroote MA, Honda JR, Chan MM, Kasperbauer S, Walter ND, Chan ED. Treatment of Non-Tuberculous Mycobacterial Lung Disease. Curr Treat Options Infect Dis. 2016 Dec; 8(4):275-296. PMID: 28529461.
      View in: PubMed
    92. Walter ND, de Jong BC, Garcia BJ, Dolganov GM, Worodria W, Byanyima P, Musisi E, Huang L, Chan ED, Van TT, Antonio M, Ayorinde A, Kato-Maeda M, Nahid P, Leung AM, Yen A, Fingerlin TE, Kechris K, Strong M, Voskuil MI, Davis JL, Schoolnik GK. Adaptation of Mycobacterium tuberculosis to Impaired Host Immunity in HIV-Infected Patients. J Infect Dis. 2016 10 15; 214(8):1205-11. PMID: 27534685.
      View in: PubMed
    93. Foster CL, Badlam J, De Groote MA, Chan ED. A 65-Year-Old Groundskeeper With High Fever, Pulmonary Nodules, and Thoracic Lymphadenopathy. Chest. 2016 Jun; 149(6):e191-4. PMID: 27287596.
      View in: PubMed
    94. Bai X, Oberley-Deegan RE, Bai A, Ovrutsky AR, Kinney WH, Weaver M, Zhang G, Honda JR, Chan ED. Curcumin enhances human macrophage control of Mycobacterium tuberculosis infection. Respirology. 2016 Jul; 21(5):951-7. PMID: 27012592.
      View in: PubMed
    95. Fox GJ, Mitnick CD, Benedetti A, Chan ED, Becerra M, Chiang CY, Keshavjee S, Koh WJ, Shiraishi Y, Viiklepp P, Yim JJ, Pasvol G, Robert J, Shim TS, Shin SS, Menzies D, Ahuja S, Ashkin D, Avenda?o M, Banerjee R, Bauer M, Burgos M, Centis R, Cobelens F, Cox H, D'Ambrosio L, de Lange WCM, DeRiemer K, Enarson D, Falzon D, Flanagan K, Flood J, Gandhi N, Garcia-Garcia L, Granich RM, Hollm-Delgado MG, Holtz TH, Hopewell P, Iseman M, Jarlsberg LG, Kim HR, Lancaster J, Lange C, Leimane V, Leung CC, Li J, Menzies D, Migliori GB, Narita M, Nathanson E, Odendaal R, O'Riordan P, Pai M, Palmero D, Park SK, Pena J, P?rez-Guzm?n C, Ponce-de-Leon A, Quelapio MID, Quy HT, Riekstina V, Royce S, Salim M, Schaaf HS, Seung KJ, Shah L, Shean K, Sifuentes-Osornio J, Sotgiu G, Strand MJ, Sung SW, Tabarsi P, Tupasi TE, Vargas MH, van Altena R, van der Walt M, van der Werf TS, Westenhouse J, Yew WW. Surgery as an Adjunctive Treatment for Multidrug-Resistant Tuberculosis: An Individual Patient Data Metaanalysis. Clin Infect Dis. 2016 Apr 01; 62(7):887-895. PMID: 26757804.
      View in: PubMed
    96. Abe J, Alop-Mabuti A, Burger P, Button J, Ellsberry M, Hitzeman J, Morgenstern D, Nunies K, Strother M, Darling-Munson J, Chan YL, Cassady R, Vasconcellos SM, Iseman MD, Chan ED, Honda JR. Comparing the temporal colonization and microbial diversity of showerhead biofilms in Hawai'i and Colorado. FEMS Microbiol Lett. 2016 Feb; 363(4). PMID: 26764424.
      View in: PubMed
    97. Bai X, Dinarello CA, Chan ED. The role of interleukin-32 against tuberculosis. Cytokine. 2015 Dec; 76(2):585-587. PMID: 26144292.
      View in: PubMed
    98. Honda JR, Hess T, Malcolm KC, Ovrutsky AR, Bai X, Irani VR, Dobos KM, Chan ED, Flores SC. Pathogenic nontuberculous mycobacteria resist and inactivate cathelicidin: implication of a novel role for polar mycobacterial lipids. PLoS One. 2015; 10(5):e0126994. PMID: 25993058.
      View in: PubMed
    99. Bai X, Shang S, Henao-Tamayo M, Basaraba RJ, Ovrutsky AR, Matsuda JL, Takeda K, Chan MM, Dakhama A, Kinney WH, Trostel J, Bai A, Honda JR, Achcar R, Hartney J, Joosten LA, Kim SH, Orme I, Dinarello CA, Ordway DJ, Chan ED. Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2015 Apr 21; 112(16):5111-6. PMID: 25820174.
      View in: PubMed
    100. Bishwakarma R, Kinney WH, Honda JR, Mya J, Strand MJ, Gangavelli A, Bai X, Ordway DJ, Iseman MD, Chan ED. Epidemiologic link between tuberculosis and cigarette/biomass smoke exposure: Limitations despite the vast literature. Respirology. 2015 May; 20(4):556-68. PMID: 25808744.
      View in: PubMed
    101. Bai X, Kinney WH, Su WL, Bai A, Ovrutsky AR, Honda JR, Netea MG, Henao-Tamayo M, Ordway DJ, Dinarello CA, Chan ED. Caspase-3-independent apoptotic pathways contribute to interleukin-32?-mediated control of Mycobacterium tuberculosis infection in THP-1 cells. BMC Microbiol. 2015 Feb 21; 15:39. PMID: 25887904.
      View in: PubMed
    102. Chan E, Anderson CS, Wang X, Arima H, Saxena A, Moullaali TJ, Heeley E, Delcourt C, Wu G, Wang J, Chen G, Lavados PM, Stapf C, Robinson T, Chalmers J, Huang Y. Significance of intraventricular hemorrhage in acute intracerebral hemorrhage: intensive blood pressure reduction in acute cerebral hemorrhage trial results. Stroke. 2015 Mar; 46(3):653-8. PMID: 25677598.
      View in: PubMed
    103. Honda JR, Bernhard JN, Chan ED. Natural disasters and nontuberculous mycobacteria: a recipe for increased disease? Chest. 2015 Feb; 147(2):304-308. PMID: 25644904.
      View in: PubMed
    104. Honda JR, Wallace RJ, Chan ED. First you have to row a little boat. Respirology. 2015 Feb; 20(2):181-2. PMID: 25581353.
      View in: PubMed
    105. Honda JR, Knight V, Chan ED. Pathogenesis and risk factors for nontuberculous mycobacterial lung disease. Clin Chest Med. 2015 Mar; 36(1):1-11. PMID: 25676515.
      View in: PubMed
    106. Chan ED, Kinney WH, Honda JR, Bishwakarma R, Gangavelli A, Mya J, Bai X, Ordway DJ. Tobacco exposure and susceptibility to tuberculosis: is there a smoking gun? Tuberculosis (Edinb). 2014 Dec; 94(6):544-50. PMID: 25305002.
      View in: PubMed
    107. Kim E, Kinney WH, Ovrutsky AR, Vo D, Bai X, Honda JR, Marx G, Peck E, Lindberg L, Falkinham JO, May RM, Chan ED. A surface with a biomimetic micropattern reduces colonization of Mycobacterium abscessus. FEMS Microbiol Lett. 2014 Nov; 360(1):17-22. PMID: 25155501.
      View in: PubMed
    108. Wu GC, Chan ED, Chou YC, Yu CY, Hsieh TY, Hsieh CB, Chian CF, Ke FC, Dai YL, Su WL. Risk factors for the development of pulmonary oil embolism after transcatheter arterial chemoembolization of hepatic tumors. Anticancer Drugs. 2014 Sep; 25(8):976-81. PMID: 24736105.
      View in: PubMed
    109. Honda JR, Connick E, MaWhinney S, Chan ED, Flores SC. Plasma LL-37 correlates with vitamin D and is reduced in human immunodeficiency virus-1 infected individuals not receiving antiretroviral therapy. J Med Microbiol. 2014 Jul; 63(Pt 7):997-1003. PMID: 24821067.
      View in: PubMed
    110. Czaja CA, Merkel PA, Chan ED, Lenz LL, Wolf ML, Alam R, Frankel SK, Fischer A, Gogate S, Perez-Velez CM, Knight V. Rituximab as successful adjunct treatment in a patient with disseminated nontuberculous mycobacterial infection due to acquired anti-interferon-? autoantibody. Clin Infect Dis. 2014 Mar; 58(6):e115-8. PMID: 24336756.
      View in: PubMed
    111. Chan MM, Chan MM, Mengshol JA, Fish DN, Chan ED. Octreotide: a drug often used in the critical care setting but not well understood. Chest. 2013 Dec; 144(6):1937-1945. PMID: 24297127.
      View in: PubMed
    112. Ovrutsky AR, Merkel PA, Schonteich E, Bai X, Kinney W, Iseman MD, Kartalija M, Knight V, Chan ED. Patients with non-tuberculous mycobacterial lung disease have elevated transforming growth factor-beta following ex vivo stimulation of blood with live Mycobacterium intracellulare. Scand J Infect Dis. 2013 Sep; 45(9):711-4. PMID: 23808720.
      View in: PubMed
    113. Talbert J, Chan ED. The association between body shape and nontuberculous mycobacterial lung disease. Expert Rev Respir Med. 2013 Jun; 7(3):201-4. PMID: 23734642.
      View in: PubMed
    114. Chan ED, Iseman MD. Surgery for MDR-TB? Int J Tuberc Lung Dis. 2013 May; 17(5):710. PMID: 23575341.
      View in: PubMed
    115. Bai X, Feldman NE, Chmura K, Ovrutsky AR, Su WL, Griffin L, Pyeon D, McGibney MT, Strand MJ, Numata M, Murakami S, Gaido L, Honda JR, Kinney WH, Oberley-Deegan RE, Voelker DR, Ordway DJ, Chan ED. Inhibition of nuclear factor-kappa B activation decreases survival of Mycobacterium tuberculosis in human macrophages. PLoS One. 2013; 8(4):e61925. PMID: 23634218.
      View in: PubMed
    116. Chan ED, Chan MM, Chan MM. Pulse oximetry: understanding its basic principles facilitates appreciation of its limitations. Respir Med. 2013 Jun; 107(6):789-99. PMID: 23490227.
      View in: PubMed
    117. Ovrutsky AR, Chan ED, Kartalija M, Bai X, Jackson M, Gibbs S, Falkinham JO, Iseman MD, Reynolds PR, McDonnell G, Thomas V. Cooccurrence of free-living amoebae and nontuberculous Mycobacteria in hospital water networks, and preferential growth of Mycobacterium avium in Acanthamoeba lenticulata. Appl Environ Microbiol. 2013 May; 79(10):3185-92. PMID: 23475613.
      View in: PubMed
    118. Chan ED, Iseman MD. Underlying host risk factors for nontuberculous mycobacterial lung disease. Semin Respir Crit Care Med. 2013 Feb; 34(1):110-23. PMID: 23460011.
      View in: PubMed
    119. Malcolm KC, Nichols EM, Caceres SM, Kret JE, Martiniano SL, Sagel SD, Chan ED, Caverly L, Solomon GM, Reynolds P, Bratton DL, Taylor-Cousar JL, Nichols DP, Saavedra MT, Nick JA. Mycobacterium abscessus induces a limited pattern of neutrophil activation that promotes pathogen survival. PLoS One. 2013; 8(2):e57402. PMID: 23451220.
      View in: PubMed
    120. Wang CH, Chan ED, Perng CL, Chian CF, Chen CW, Perng WC, Su WL. Intravenous immunoglobulin replacement therapy to prevent pulmonary infection in a patient with Good's syndrome. J Microbiol Immunol Infect. 2015 Apr; 48(2):229-32. PMID: 23200552.
      View in: PubMed
    121. Kartalija M, Ovrutsky AR, Bryan CL, Pott GB, Fantuzzi G, Thomas J, Strand MJ, Bai X, Ramamoorthy P, Rothman MS, Nagabhushanam V, McDermott M, Levin AR, Frazer-Abel A, Giclas PC, Korner J, Iseman MD, Shapiro L, Chan ED. Patients with nontuberculous mycobacterial lung disease exhibit unique body and immune phenotypes. Am J Respir Crit Care Med. 2013 Jan 15; 187(2):197-205. PMID: 23144328.
      View in: PubMed
    122. Chan ED, Pott GB, Silkoff PE, Ralston AH, Bryan CL, Shapiro L. Alpha-1-antitrypsin inhibits nitric oxide production. J Leukoc Biol. 2012 Dec; 92(6):1251-60. PMID: 22975343.
      View in: PubMed
    123. Walter ND, Strong M, Belknap R, Ordway DJ, Daley CL, Chan ED. Translating basic science insight into public health action for multidrug- and extensively drug-resistant tuberculosis. Respirology. 2012 Jul; 17(5):772-91. PMID: 22458269.
      View in: PubMed
    124. Marx GE, Chan ED. Tuberculous meningitis: diagnosis and treatment overview. Tuberc Res Treat. 2011; 2011:798764. PMID: 22567269.
      View in: PubMed
    125. Bai X, Ovrutsky AR, Kartalija M, Chmura K, Kamali A, Honda JR, Oberley-Deegan RE, Dinarello CA, Crapo JD, Chang LY, Chan ED. IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease. Int Immunol. 2011 Nov; 23(11):679-91. PMID: 22033195.
      View in: PubMed
    126. Honda JR, Shang S, Shanley CA, Caraway ML, Henao-Tamayo M, Chan ED, Basaraba RJ, Orme IM, Ordway DJ, Flores SC. Immune Responses of HIV-1 Tat Transgenic Mice to Mycobacterium Tuberculosis W-Beijing SA161. Open AIDS J. 2011; 5:86-95. PMID: 22046211.
      View in: PubMed
    127. Ovrutsky AR, Kartalija M, Bai X, Chan ED. A trojan horse strategy to deliver amikacin to mycobacterial granulomas. Am J Respir Crit Care Med. 2011 Oct 01; 184(7):860; author reply 860-1. PMID: 21965019.
      View in: PubMed
    128. Coffey D, Fain B, Thompson C, Chan ED, Nawaz S. Liver failure as the only clinical manifestation of multiple myeloma. Ann Hematol. 2012 Apr; 91(4):625-7. PMID: 21732087.
      View in: PubMed
    129. Shang S, Harton M, Tamayo MH, Shanley C, Palanisamy GS, Caraway M, Chan ED, Basaraba RJ, Orme IM, Ordway DJ. Increased Foxp3 expression in guinea pigs infected with W-Beijing strains of M. tuberculosis. Tuberculosis (Edinb). 2011 Sep; 91(5):378-85. PMID: 21737349.
      View in: PubMed
    130. Shang S, Ordway D, Henao-Tamayo M, Bai X, Oberley-Deegan R, Shanley C, Orme IM, Case S, Minor M, Ackart D, Hascall-Dove L, Ovrutsky AR, Kandasamy P, Voelker DR, Lambert C, Freed BM, Iseman MD, Basaraba RJ, Chan ED. Cigarette smoke increases susceptibility to tuberculosis--evidence from in vivo and in vitro models. J Infect Dis. 2011 May 01; 203(9):1240-8. PMID: 21357942.
      View in: PubMed
    131. Kandasamy P, Zarini S, Chan ED, Leslie CC, Murphy RC, Voelker DR. Pulmonary surfactant phosphatidylglycerol inhibits Mycoplasma pneumoniae-stimulated eicosanoid production from human and mouse macrophages. J Biol Chem. 2011 Mar 11; 286(10):7841-7853. PMID: 21205826.
      View in: PubMed
    132. Walter ND, Rice PL, Redente EF, Kauvar EF, Lemond L, Aly T, Wanebo K, Chan ED. Wound healing after trauma may predispose to lung cancer metastasis: review of potential mechanisms. Am J Respir Cell Mol Biol. 2011 May; 44(5):591-6. PMID: 21177982.
      View in: PubMed
    133. Bai X, Chmura K, Ovrutsky AR, Bowler RP, Scheinman RI, Oberley-Deegan RE, Liu H, Shang S, Ordway D, Chan ED. Mycobacterium tuberculosis increases IP-10 and MIG protein despite inhibition of IP-10 and MIG transcription. Tuberculosis (Edinb). 2011 Jan; 91(1):26-35. PMID: 21167783.
      View in: PubMed
    134. Mor? JM, Voelker DR, Silveira LJ, Edwards MG, Chan ED, Bowler RP. Smoking reduces surfactant protein D and phospholipids in patients with and without chronic obstructive pulmonary disease. BMC Pulm Med. 2010 Oct 25; 10:53. PMID: 20973980.
      View in: PubMed
    135. Chan ED, Keane J, Iseman MD. Should cigarette smoke exposure be a criterion to treat latent tuberculous infection? Am J Respir Crit Care Med. 2010 Oct 15; 182(8):990-2. PMID: 20947905.
      View in: PubMed
    136. Oberley-Deegan RE, Rebits BW, Weaver MR, Tollefson AK, Bai X, McGibney M, Ovrutsky AR, Chan ED, Crapo JD. An oxidative environment promotes growth of Mycobacterium abscessus. Free Radic Biol Med. 2010 Dec 01; 49(11):1666-73. PMID: 20807564.
      View in: PubMed
    137. Gingo M, Risbano MG, Russ PD, Chan ED. Not your otitis media 101. Am J Med. 2010 Aug; 123(8):e9-e11. PMID: 20670714.
      View in: PubMed
    138. Bai X, Kim SH, Azam T, McGibney MT, Huang H, Dinarello CA, Chan ED. IL-32 is a host protective cytokine against Mycobacterium tuberculosis in differentiated THP-1 human macrophages. J Immunol. 2010 Apr 01; 184(7):3830-40. PMID: 20190143.
      View in: PubMed
    139. Chan ED, Iseman MD. Slender, older women appear to be more susceptible to nontuberculous mycobacterial lung disease. Gend Med. 2010 Feb; 7(1):5-18. PMID: 20189150.
      View in: PubMed
    140. Chan ED, Bai X, Kartalija M, Orme IM, Ordway DJ. Host immune response to rapidly growing mycobacteria, an emerging cause of chronic lung disease. Am J Respir Cell Mol Biol. 2010 Oct; 43(4):387-93. PMID: 20081053.
      View in: PubMed
    141. Hong J, Bae S, Kang Y, Yoon D, Bai X, Chan ED, Azam T, Dinarello CA, Lee S, Her E, Rho G, Kim S. Suppressing IL-32 in monocytes impairs the induction of the proinflammatory cytokines TNFalpha and IL-1beta. Cytokine. 2010 Feb; 49(2):171-6. PMID: 19880327.
      View in: PubMed
    142. Bedient TJ, Schwarz MI, Groshong SD, Chan ED. A 45-year-old man with a history of hepatitis C and testicular cancer presents with cavitary lung lesions and palpable purpura. Chest. 2009 Oct; 136(4):1168-1174. PMID: 19809061.
      View in: PubMed
    143. Kuronuma K, Mitsuzawa H, Takeda K, Nishitani C, Chan ED, Kuroki Y, Nakamura M, Voelker DR. Anionic pulmonary surfactant phospholipids inhibit inflammatory responses from alveolar macrophages and U937 cells by binding the lipopolysaccharide-interacting proteins CD14 and MD-2. J Biol Chem. 2009 Sep 18; 284(38):25488-500. PMID: 19584052.
      View in: PubMed
    144. Morris KR, Lutz RD, Bai X, McGibney MT, Cook D, Ordway D, Chan ED. Suppression of IFNgamma+mycobacterial lipoarabinomannan-induced NO by IL-4 is due to decreased IRF-1 expression. Tuberculosis (Edinb). 2009 Jul; 89(4):294-303. PMID: 19556165.
      View in: PubMed
    145. Bai X, Silvius D, Chan ED, Escalier D, Xu SX. Identification and characterization of a novel testis-specific gene CKT2, which encodes a substrate for protein kinase CK2. Nucleic Acids Res. 2009 May; 37(8):2699-711. PMID: 19273531.
      View in: PubMed
    146. Chan ED, Strand MJ, Iseman MD. Multidrug-resistant tuberculosis (TB) resistant to fluoroquinolones and streptomycin but susceptible to second-line injection therapy has a better prognosis than extensively drug-resistant TB. Clin Infect Dis. 2009 Mar 01; 48(5):e50-2. PMID: 19191632.
      View in: PubMed
    147. Pott GB, Chan ED, Dinarello CA, Shapiro L. Alpha-1-antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood. J Leukoc Biol. 2009 May; 85(5):886-95. PMID: 19197072.
      View in: PubMed
    148. Oberley-Deegan RE, Lee YM, Morey GE, Cook DM, Chan ED, Crapo JD. The antioxidant mimetic, MnTE-2-PyP, reduces intracellular growth of Mycobacterium abscessus. Am J Respir Cell Mol Biol. 2009 Aug; 41(2):170-8. PMID: 19097985.
      View in: PubMed
    149. Chan ED, Iseman MD. Multidrug-resistant and extensively drug-resistant tuberculosis: a review. Curr Opin Infect Dis. 2008 Dec; 21(6):587-95. PMID: 18978526.
      View in: PubMed
    150. Chan ED, Strand MJ, Iseman MD. Treatment outcomes in extensively resistant tuberculosis. N Engl J Med. 2008 Aug 07; 359(6):657-9. PMID: 18687654.
      View in: PubMed
    151. Chan ED, Iseman MD. Significance of bronchiectasis in patients with alpha1-antitrypsin deficiency. Am J Respir Crit Care Med. 2008 Jul 15; 178(2):208; author reply 208-9. PMID: 18594121.
      View in: PubMed
    152. Chmura K, Bai X, Nakamura M, Kandasamy P, McGibney M, Kuronuma K, Mitsuzawa H, Voelker DR, Chan ED. Induction of IL-8 by Mycoplasma pneumoniae membrane in BEAS-2B cells. Am J Physiol Lung Cell Mol Physiol. 2008 Jul; 295(1):L220-30. PMID: 18487355.
      View in: PubMed
    153. Miller RM, Tomaras AP, Barker AP, Voelker DR, Chan ED, Vasil AI, Vasil ML. Pseudomonas aeruginosa twitching motility-mediated chemotaxis towards phospholipids and fatty acids: specificity and metabolic requirements. J Bacteriol. 2008 Jun; 190(11):4038-49. PMID: 18390654.
      View in: PubMed
    154. Chan ED. Corticosteroids for bacterial meningitis. N Engl J Med. 2008 Mar 27; 358(13):1399; author reply 1400-1. PMID: 18367746.
      View in: PubMed
    155. Sergew A, Merrick D, Chan ED. A 64-year-old man with joint swelling and an abnormal chest radiograph. Chest. 2008 Mar; 133(3):805-8. PMID: 18321909.
      View in: PubMed
    156. Ordway D, Henao-Tamayo M, Smith E, Shanley C, Harton M, Troudt J, Bai X, Basaraba RJ, Orme IM, Chan ED. Animal model of Mycobacterium abscessus lung infection. J Leukoc Biol. 2008 Jun; 83(6):1502-11. PMID: 18310351.
      View in: PubMed
    157. Liu L, Bastien N, Sidaway F, Chan E, Li Y. Seroprevalence of human metapneumovirus (hMPV) in the Canadian province of Saskatchewan analyzed by a recombinant nucleocapsid protein-based enzyme-linked immunosorbent assay. J Med Virol. 2007 Mar; 79(3):308-13. PMID: 17245714.
      View in: PubMed
    158. Morimoto Y, Chan ED, Heifets L, Routes JM. Pulmonary infection with Mycobacterium neoaurum identified by 16S ribosomal DNA sequence. J Infect. 2007 Apr; 54(4):e227-31. PMID: 17306883.
      View in: PubMed
    159. Chan ED, Kaminska AM, Gill W, Chmura K, Feldman NE, Bai X, Floyd CM, Fulton KE, Huitt GA, Strand MJ, Iseman MD, Shapiro L. Alpha-1-antitrypsin (AAT) anomalies are associated with lung disease due to rapidly growing mycobacteria and AAT inhibits Mycobacterium abscessus infection of macrophages. Scand J Infect Dis. 2007; 39(8):690-6. PMID: 17654345.
      View in: PubMed
    160. Gray K, Chan ED, Alvarado J. A 48-year-old woman with multiple pulmonary nodules and a right ventricular mass. Chest. 2006 Oct; 130(4):1248-51. PMID: 17035464.
      View in: PubMed
    161. Netea MG, Azam T, Lewis EC, Joosten LA, Wang M, Langenberg D, Meng X, Chan ED, Yoon DY, Ottenhoff T, Kim SH, Dinarello CA. Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism. PLoS Med. 2006 Aug; 3(8):e277. PMID: 16903774.
      View in: PubMed
    162. Sullivan A, Chmura K, Cool CD, Keith R, Schwartz GG, Chan ED. Pulmonary capillary hemangiomatosis: an immunohistochemical analysis of vascular remodeling. Eur J Med Res. 2006 May 05; 11(5):187-93. PMID: 16723291.
      View in: PubMed
    163. Chan MM, Chmura K, Chan ED. Increased NaCl-induced interleukin-8 production by human bronchial epithelial cells is enhanced by the DeltaF508/W1282X mutation of the cystic fibrosis transmembrane conductance regulator gene. Cytokine. 2006 Mar 21; 33(6):309-16. PMID: 16647268.
      View in: PubMed
    164. Sullivan A, Chmura K, Cool CD, Voelkel N, Chan ED. Pulmonary capillary hemangiomatosis: an immunohistochemical analysis of vascular remodeling in a fatal case. Chest. 2005 Dec; 128(6 Suppl):576S. PMID: 16373838.
      View in: PubMed
    165. Wieland CW, Florquin S, Chan ED, Leemans JC, Weijer S, Verbon A, Fantuzzi G, van der Poll T. Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice. Int Immunol. 2005 Nov; 17(11):1399-408. PMID: 16141243.
      View in: PubMed
    166. Chmura K, Chan ED, Noone PG, Zariwala M, Winn RA, Knowles MR, Iseman MD, Gardner EM. A middle-aged woman with recurrent respiratory infections. Respiration. 2005 Jul-Aug; 72(4):427-30. PMID: 16088289.
      View in: PubMed
    167. Gruber MP, Nana-Sinkam SP, Chan ED. Airflow limitation and dynamic gas trapping in a bone marrow transplant recipient. Respir Care. 2004 Dec; 49(12):1542-5. PMID: 15603056.
      View in: PubMed
    168. Winn RA, Chan ED, Langmack EL, Kotaru C, Aronsen E. Dysphagia, chest pain, and refractory asthma in a 42-year-old woman. Chest. 2004 Nov; 126(5):1694-7. PMID: 15539746.
      View in: PubMed
    169. Bowler RP, Duda B, Vu KO, Byers T, Franklin W, Chan ED, Miller YE. Airway antioxidants and oxidative stress as predictors of sputum atypia and airflow obstruction. Chest. 2004 May; 125(5 Suppl):127S-8S. PMID: 15136460.
      View in: PubMed
    170. Kalman D, Lee A, Chan E, Miller DR, Spiro A, Ren XS, Kazis LE. Alcohol dependence, other psychiatric disorders, and health-related quality of life: a replication study in a large random sample of enrollees in the Veterans Health Administration. Am J Drug Alcohol Abuse. 2004 May; 30(2):473-87. PMID: 15230087.
      View in: PubMed
    171. Bowler RP, Duda B, Chan ED, Enghild JJ, Ware LB, Matthay MA, Duncan MW. Proteomic analysis of pulmonary edema fluid and plasma in patients with acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2004 Jun; 286(6):L1095-104. PMID: 14742308.
      View in: PubMed
    172. Chan ED, Laurel V, Strand MJ, Chan JF, Huynh ML, Goble M, Iseman MD. Treatment and outcome analysis of 205 patients with multidrug-resistant tuberculosis. Am J Respir Crit Care Med. 2004 May 15; 169(10):1103-9. PMID: 14742301.
      View in: PubMed
    173. Bai X, Wilson SE, Chmura K, Feldman NE, Chan ED. Morphometric analysis of Th(1) and Th(2) cytokine expression in human pulmonary tuberculosis. Tuberculosis (Edinb). 2004; 84(6):375-85. PMID: 15525561.
      View in: PubMed
    174. Bastien N, Ward D, Van Caeseele P, Brandt K, Lee SH, McNabb G, Klisko B, Chan E, Li Y. Human metapneumovirus infection in the Canadian population. J Clin Microbiol. 2003 Oct; 41(10):4642-6. PMID: 14532196.
      View in: PubMed
    175. Bowler RP, Velsor LW, Duda B, Chan ED, Abraham E, Ware LB, Matthay MA, Day BJ. Pulmonary edema fluid antioxidants are depressed in acute lung injury. Crit Care Med. 2003 Sep; 31(9):2309-15. PMID: 14501961.
      View in: PubMed
    176. Bai X, Chan ED, Xu X. The protein of a new gene, Tctex4, interacts with protein kinase CK2beta subunit and is highly expressed in mouse testis. Biochem Biophys Res Commun. 2003 Jul 18; 307(1):86-91. PMID: 12849985.
      View in: PubMed
    177. Chmura K, Cool C, Kircher T, Chan ED. Painful lymphadenopathy and fulminant sepsis in a previously healthy 16-year-old girl. Chest. 2003 Jul; 124(1):379-82. PMID: 12853549.
      View in: PubMed
    178. Chan MM, Chan MM, Chan ED. What is the effect of fingernail polish on pulse oximetry? Chest. 2003 Jun; 123(6):2163-4. PMID: 12796214.
      View in: PubMed
    179. Morris KR, Lutz RD, Choi HS, Kamitani T, Chmura K, Chan ED. Role of the NF-kappaB signaling pathway and kappaB cis-regulatory elements on the IRF-1 and iNOS promoter regions in mycobacterial lipoarabinomannan induction of nitric oxide. Infect Immun. 2003 Mar; 71(3):1442-52. PMID: 12595462.
      View in: PubMed
    180. Chmura K, Lutz RD, Chiba H, Numata MS, Choi HJ, Fantuzzi G, Voelker DR, Chan ED. Mycoplasma pneumoniae antigens stimulate interleukin-8. Chest. 2003 Mar; 123(3 Suppl):425S. PMID: 12629012.
      View in: PubMed
    181. Choi HS, Rai PR, Chu HW, Cool C, Chan ED. Analysis of nitric oxide synthase and nitrotyrosine expression in human pulmonary tuberculosis. Am J Respir Crit Care Med. 2002 Jul 15; 166(2):178-86. PMID: 12119230.
      View in: PubMed
    182. Chan ED, Choi HS, Cool C, Accurso FJ, Fantuzzi G. Interleukin-18 expression in cystic fibrosis lungs. Chest. 2002 Mar; 121(3 Suppl):84S-85S. PMID: 11893709.
      View in: PubMed
    183. Tse HM, Josephy SI, Chan ED, Fouts D, Cooper AM. Activation of the mitogen-activated protein kinase signaling pathway is instrumental in determining the ability of Mycobacterium avium to grow in murine macrophages. J Immunol. 2002 Jan 15; 168(2):825-33. PMID: 11777978.
      View in: PubMed
    Chan's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    See all (711) concept(s)
    _
    Co-Authors Expand Description
    See all (84) people
    _
    Similar People Expand Description
    See all (60) people
    _
    Same Department Expand Description
    Search Department

    Copyright © 2024 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)