 Polypharmacy
"Polypharmacy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The use of multiple drugs administered to the same patient, most commonly seen in elderly patients. It includes also the administration of excessive medication. Since in the United States most drugs are dispensed as single-agent formulations, polypharmacy, though using many drugs administered to the same patient, must be differentiated from DRUG COMBINATIONS, single preparations containing two or more drugs as a fixed dose, and from DRUG THERAPY, COMBINATION, two or more drugs administered separately for a combined effect. (From Segen, Dictionary of Modern Medicine, 1992)
| Descriptor ID |
D019338
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| MeSH Number(s) |
E02.319.698
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Polypharmacy".
Below are MeSH descriptors whose meaning is more specific than "Polypharmacy".
This graph shows the total number of publications written about "Polypharmacy" by people in this website by year, and whether "Polypharmacy" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 2 | 0 | 2 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2014 | 0 | 2 | 2 | | 2015 | 5 | 3 | 8 | | 2016 | 3 | 3 | 6 | | 2017 | 1 | 1 | 2 | | 2018 | 2 | 1 | 3 | | 2019 | 4 | 2 | 6 | | 2020 | 1 | 0 | 1 | | 2021 | 2 | 2 | 4 | | 2022 | 1 | 2 | 3 |
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Below are the most recent publications written about "Polypharmacy" by people in Profiles.
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Goyal P, Safford MM, Hilmer SN, Steinman MA, Matlock DD, Maurer MS, Lachs MS, Kronish IM. N-of-1 trials to facilitate evidence-based deprescribing: Rationale and case study. Br J Clin Pharmacol. 2022 Oct; 88(10):4460-4473.
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Psomas CK, Hoover DR, Shi Q, Brown TT, Vance DE, Holman S, Plankey MW, Tien PC, Weber KM, Floris-Moore M, Bolivar HH, Golub ET, McDonnell Holstad M, Radtke KK, Tamraz B, Erlandson KM, Rubin LH, Sharma A. Polypharmacy Is Associated With Falls in Women With and Without HIV. J Acquir Immune Defic Syndr. 2022 07 01; 90(3):351-359.
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Marquez C, Thompson R, Feinstein JA, Orth LE. Identifying opportunities for pediatric medication therapy management in children with medical complexity. J Am Pharm Assoc (2003). 2022 Sep-Oct; 62(5):1587-1595.e3.
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Smith L, Letendre S, Erlandson KM, Ma Q, Ellis RJ, Farhadian SF. Polypharmacy in older adults with HIV infection: Effects on the brain. J Am Geriatr Soc. 2022 03; 70(3):924-927.
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Lohr WD, Jawad K, Feygin Y, Le J, Creel L, Pasquenza N, Williams PG, Jones VF, Myers J, Davis DW. Antipsychotic Medications for Low-Income Preschoolers: Long Duration and Psychotropic Medication Polypharmacy. Psychiatr Serv. 2022 05; 73(5):510-517.
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Simon ST, Kini V, Levy AE, Ho PM. Medication adherence in cardiovascular medicine. BMJ. 2021 08 11; 374:n1493.
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Davis DW, Lohr WD, Feygin Y, Creel L, Jawad K, Jones VF, Williams PG, Le J, Trace M, Pasquenza N. High-level psychotropic polypharmacy: a retrospective comparison of children in foster care to their peers on Medicaid. BMC Psychiatry. 2021 06 10; 21(1):303.
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Horace AE, Golchin N, Knight EMP, Dawson NV, Ma X, Feinstein JA, Johnson HK, Kleinman L, Bakaki PM. A Scoping Review of Medications Studied in Pediatric Polypharmacy Research. Paediatr Drugs. 2020 Feb; 22(1):85-94.
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Damluji AA, Forman DE, van Diepen S, Alexander KP, Page RL, Hummel SL, Menon V, Katz JN, Albert NM, Afilalo J, Cohen MG. Older Adults in the Cardiac Intensive Care Unit: Factoring Geriatric Syndromes in the Management, Prognosis, and Process of Care: A Scientific Statement From the American Heart Association. Circulation. 2020 01 14; 141(2):e6-e32.
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Goyal P, Gorodeski EZ, Flint KM, Goldwater DS, Dodson JA, Afilalo J, Maurer MS, Rich MW, Alexander KP, Hummel SL. Perspectives on Implementing a Multidomain Approach to Caring for Older Adults With Heart Failure. J Am Geriatr Soc. 2019 12; 67(12):2593-2599.
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