 Anemia, Sickle Cell
"Anemia, Sickle Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.
| Descriptor ID |
D000755
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| MeSH Number(s) |
C15.378.071.141.150.150 C15.378.420.155 C16.320.070.150 C16.320.365.155
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| Concept/Terms |
Anemia, Sickle Cell- Anemia, Sickle Cell
- Anemias, Sickle Cell
- Sickle Cell Anemias
- Hemoglobin S Disease
- Disease, Hemoglobin S
- Hemoglobin S Diseases
- Sickle Cell Anemia
- Sickle Cell Disorders
- Cell Disorder, Sickle
- Cell Disorders, Sickle
- Sickle Cell Disorder
- Sickling Disorder Due to Hemoglobin S
- HbS Disease
- Sickle Cell Disease
- Cell Disease, Sickle
- Cell Diseases, Sickle
- Sickle Cell Diseases
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Below are MeSH descriptors whose meaning is more general than "Anemia, Sickle Cell".
- Diseases [C]
- Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
- Anemia [C15.378.071]
- Anemia, Hemolytic [C15.378.071.141]
- Anemia, Hemolytic, Congenital [C15.378.071.141.150]
- Anemia, Sickle Cell [C15.378.071.141.150.150]
- Hemoglobinopathies [C15.378.420]
- Anemia, Sickle Cell [C15.378.420.155]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Anemia, Hemolytic, Congenital [C16.320.070]
- Anemia, Sickle Cell [C16.320.070.150]
- Hemoglobinopathies [C16.320.365]
- Anemia, Sickle Cell [C16.320.365.155]
Below are MeSH descriptors whose meaning is more specific than "Anemia, Sickle Cell".
This graph shows the total number of publications written about "Anemia, Sickle Cell" by people in this website by year, and whether "Anemia, Sickle Cell" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 2 | 0 | 2 | | 2004 | 1 | 0 | 1 | | 2005 | 2 | 0 | 2 | | 2007 | 2 | 0 | 2 | | 2008 | 4 | 1 | 5 | | 2009 | 2 | 1 | 3 | | 2010 | 3 | 1 | 4 | | 2011 | 11 | 1 | 12 | | 2012 | 5 | 0 | 5 | | 2013 | 2 | 1 | 3 | | 2014 | 14 | 0 | 14 | | 2015 | 8 | 0 | 8 | | 2016 | 7 | 0 | 7 | | 2017 | 6 | 0 | 6 | | 2018 | 7 | 0 | 7 | | 2019 | 11 | 0 | 11 | | 2020 | 10 | 1 | 11 | | 2021 | 10 | 1 | 11 | | 2022 | 10 | 0 | 10 | | 2023 | 15 | 0 | 15 | | 2024 | 5 | 1 | 6 | | 2025 | 6 | 0 | 6 |
To return to the timeline, click here.
Below are the most recent publications written about "Anemia, Sickle Cell" by people in Profiles.
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Coleman KD, McKinley K, Ellison AM, Alpern ER, Hariharan S, Topoz I, Wurtz M, Nielsen B, Cook LJ, Morris CR, Brandow AM, Campbell AD, Liem RI, Nuss R, Quinn CT, Thompson AA, Villella A, King AA, Baumann A, Frankenberger W, Brousseau DC. Associations Between Pain Scores and Opioid Doses With Emergency Department Disposition and Return Visit Rates in Children With Sickle Cell Disease. Pediatr Blood Cancer. 2025 Jul; 72(7):e31750.
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Walters MC, Eapen M, Liu Y, El Rassi F, Waller EK, Levine JE, Strouse JJ, Antin JH, Parikh SH, Bakshi N, Dampier C, Jaroscak JJ, Bergmann S, Wong T, Kota V, Pace B, Lekakis LJ, Lulla P, Nickel RS, Kasow KA, Popat U, Smith W, Yu L, DiFronzo N, Geller N, Kamani N, Klings ES, Hassell K, Mendizabal A, Sullivan K, Neuberg D, Krishnamurti L. Hematopoietic cell transplant compared with standard care in adolescents and young adults with sickle cell disease. Blood Adv. 2025 Mar 11; 9(5):955-965.
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Zemplenyi A, Leonard J, Wright GC, DiStefano MJ, Nair K, Anderson KE, McQueen RB. Innovative Payment Models for Sickle-Cell Disease Gene Therapies in Medicaid: Leveraging Real-World Data and Insights from CMMI's Gene Therapy Access Model. Pharmacoeconomics. 2025 May; 43(5):583-594.
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Schlenz AM, Vestal E, Abrams CM, Kanter J, Phillips S. Barriers and Facilitators to Comprehensive Pediatric Sickle Cell Care: A Qualitative Study. Pediatr Blood Cancer. 2025 May; 72(5):e31603.
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Rana NK, Lisk C, Cendali F, Lucero MJ, Grier A, Setua S, Thangaraju K, Khan A, Reisz JA, Dzieciatkowska M, Pak DI, Swindle D, Danaher MX, Khan S, Westover N, Carter M, Hassell K, Nuss R, George G, Buehler PW, D'Alessandro A, Irwin DC. Metabolic and Proteomic Divergence is Present in Spleens and Livers from Berkeley Sickle Cell Anemia and ?-Thalassemia Mice. J Proteome Res. 2025 Mar 07; 24(3):1306-1316.
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Lucero MJ, Lisk C, Cendali F, Swindle D, Setua S, Thangaraju K, Pak DI, O'Boyle Q, Lu S, Tolson R, Zaeske S, Rana N, Khan S, Westover N, DavizonCastillo P, George G, Hassell K, Nuss R, Brinkman N, Gentinetta T, Palmer AF, D'Alessandro A, Buehler PW, Irwin DC. Targeting lung heme iron by aerosol hemopexin adminstration in sickle cell disease pulmonary hypertension. Free Radic Biol Med. 2025 Mar 01; 229:458-473.
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Miller JI, Hassell KL, Kellar-Guenther Y, Quesada S, West R, Sontag M. The Prevalence of Sickle Cell Disease in Colorado and Methodologies of the Colorado Sickle Cell Data Collection Program: Public Health Surveillance Study. JMIR Public Health Surveill. 2024 Dec 09; 10:e64995.
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Reisz JA, Earley EJ, Nemkov T, Key A, Stephenson D, Keele GR, Dzieciatkowska M, Spitalnik SL, Hod EA, Kleinman S, Roubinian NH, Gladwin MT, Hansen KC, Norris PJ, Busch MP, Zimring JC, Churchill GA, Page GP, D'Alessandro A. Arginine metabolism is a biomarker of red blood cell and human aging. Aging Cell. 2025 Feb; 24(2):e14388.
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Irwin DC, Calvo ETN, Belbis MD, Ehrenfort SKC, Noguer M, Messonnier LA, Buehler PW, Hirai DM, Ferguson SK. Understanding exercise (in)tolerance in sickle cell disease: impacts of hemolysis and exercise training on skeletal muscle oxygen delivery. J Appl Physiol (1985). 2024 Oct 01; 137(4):975-983.
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D'Alessandro A, Le K, Lundt M, Li Q, Dunkelberger EB, Cellmer T, Worth AJ, Patil S, Huston C, Grier A, Dzieciatkowska M, Stephenson D, Eaton WA, Thein SL. Functional and multi-omics signatures of mitapivat efficacy upon activation of pyruvate kinase in red blood cells from patients with sickle cell disease. Haematologica. 2024 08 01; 109(8):2639-2652.
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