 Leukemia
"Leukemia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Descriptor ID |
D007938
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| MeSH Number(s) |
C04.557.337
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| Concept/Terms |
Leukemia- Leukemia
- Leukemias
- Leucocythaemia
- Leucocythaemias
- Leucocythemia
- Leucocythemias
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Below are MeSH descriptors whose meaning is more general than "Leukemia".
Below are MeSH descriptors whose meaning is more specific than "Leukemia".
This graph shows the total number of publications written about "Leukemia" by people in this website by year, and whether "Leukemia" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 | | 1993 | 1 | 1 | 2 | | 1994 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1996 | 0 | 2 | 2 | | 1997 | 1 | 1 | 2 | | 1998 | 1 | 0 | 1 | | 1999 | 0 | 3 | 3 | | 2000 | 2 | 0 | 2 | | 2001 | 1 | 3 | 4 | | 2002 | 2 | 0 | 2 | | 2003 | 2 | 1 | 3 | | 2004 | 4 | 2 | 6 | | 2005 | 4 | 0 | 4 | | 2006 | 3 | 0 | 3 | | 2007 | 4 | 1 | 5 | | 2008 | 4 | 2 | 6 | | 2009 | 6 | 1 | 7 | | 2010 | 6 | 2 | 8 | | 2011 | 3 | 2 | 5 | | 2012 | 4 | 2 | 6 | | 2013 | 2 | 2 | 4 | | 2014 | 5 | 1 | 6 | | 2015 | 6 | 2 | 8 | | 2016 | 8 | 3 | 11 | | 2017 | 7 | 1 | 8 | | 2018 | 6 | 2 | 8 | | 2019 | 9 | 0 | 9 | | 2020 | 4 | 0 | 4 | | 2021 | 3 | 0 | 3 |
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Below are the most recent publications written about "Leukemia" by people in Profiles.
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Rogawski DS, Deng J, Li H, Miao H, Borkin D, Purohit T, Song J, Chase J, Li S, Ndoj J, Klossowski S, Kim E, Mao F, Zhou B, Ropa J, Krotoska MZ, Jin Z, Ernst P, Feng X, Huang G, Nishioka K, Kelly S, He M, Wen B, Sun D, Muntean A, Dou Y, Maillard I, Cierpicki T, Grembecka J. Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity. Nat Commun. 2021 05 14; 12(1):2792.
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Jones CL, Inguva A, Jordan CT. Targeting Energy Metabolism in Cancer Stem Cells: Progress and Challenges in Leukemia and Solid Tumors. Cell Stem Cell. 2021 03 04; 28(3):378-393.
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Ciavattone NG, Wu L, O'Neill R, Qiu J, Davila E, Cao X. MyD88 Costimulation in Donor CD8+ T Cells Enhances the Graft-versus-Tumor Effect in Murine Hematopoietic Cell Transplantation. J Immunol. 2021 02 15; 206(4):892-903.
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Do P, Perdue LA, Chyong A, Hunter R, Dougan J, Henry CJ, Porter CC, Dreaden EC. Rapid Assembly and Screening of Multivalent Immune Cell-Redirecting Therapies for Leukemia. ACS Comb Sci. 2020 10 12; 22(10):533-541.
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Kahn JM, Brazauskas R, Tecca HR, Bo-Subait S, Buchbinder D, Battiwala M, Flowers MED, Savani BN, Phelan R, Broglie L, Abraham AA, Keating AK, Daly A, Wirk B, George B, Alter BP, Ustun C, Freytes CO, Beitinjaneh AM, Duncan C, Copelan E, Hildebrandt GC, Murthy HS, Lazarus HM, Auletta JJ, Myers KC, Williams KM, Page KM, Vrooman LM, Norkin M, Byrne M, Diaz MA, Kamani N, Bhatt NS, Rezvani A, Farhadfar N, Mehta PA, Hematti P, Shaw PJ, Kamble RT, Schears R, Olsson RF, Hayashi RJ, Gale RP, Mayo SJ, Chhabra S, Rotz SJ, Badawy SM, Ganguly S, Pavletic S, Nishihori T, Prestidge T, Agrawal V, Hogan WJ, Inamoto Y, Shaw BE, Satwani P. Subsequent neoplasms and late mortality in children undergoing allogeneic transplantation for nonmalignant diseases. Blood Adv. 2020 05 12; 4(9):2084-2094.
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Liu H, Lee S, Zhang Q, Chen Z, Zhang G. The potential underlying mechanism of the leukemia caused by MLL-fusion and potential treatments. Mol Carcinog. 2020 07; 59(7):839-851.
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Kang YA, Pietras EM, Passegué E. Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia. J Exp Med. 2020 03 02; 217(3).
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Liggett LA, Sharma A, De S, DeGregori J. FERMI: A Novel Method for Sensitive Detection of Rare Mutations in Somatic Tissue. G3 (Bethesda). 2019 09 04; 9(9):2977-2987.
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Tsamadou C, Fürst D, Wang T, He N, Lee SJ, Spellman SR, Fleischhauer K, Hsu KC, Paczesny S, Verneris MR, Schrezenmeier H, Mytilineos J. Donor HLA-E Status Associates with Disease-Free Survival and Transplant-Related Mortality after Non In Vivo T Cell-Depleted HSCT for Acute Leukemia. Biol Blood Marrow Transplant. 2019 12; 25(12):2357-2365.
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Deng Z, Zhao J, Cai S, Qi Y, Yu Q, Martin MP, Gao X, Chen R, Zhuo J, Zhen J, Zhang M, Zhang G, He L, Zou H, Lu L, Zhu W, Hong W, Carrington M, Norman PJ. Natural Killer Cells Offer Differential Protection From Leukemia in Chinese Southern Han. Front Immunol. 2019; 10:1646.
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