 Replication Origin
"Replication Origin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A unique DNA sequence of a replicon at which DNA REPLICATION is initiated and proceeds bidirectionally or unidirectionally. It contains the sites where the first separation of the complementary strands occurs, a primer RNA is synthesized, and the switch from primer RNA to DNA synthesis takes place. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
| Descriptor ID |
D018741
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| MeSH Number(s) |
G05.360.340.024.220.760 G05.360.340.024.745.725
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| Concept/Terms |
Replication Origin- Replication Origin
- Origin, Replication
- Origins, Replication
- ori Region
- Region, ori
- Regions, ori
- ori Regions
- Origin of Replication
- Replication Origins
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Below are MeSH descriptors whose meaning is more general than "Replication Origin".
Below are MeSH descriptors whose meaning is more specific than "Replication Origin".
This graph shows the total number of publications written about "Replication Origin" by people in this website by year, and whether "Replication Origin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 2002 | 1 | 2 | 3 | | 2004 | 2 | 0 | 2 | | 2008 | 2 | 0 | 2 | | 2011 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2017 | 0 | 2 | 2 | | 2021 | 0 | 1 | 1 | | 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Replication Origin" by people in Profiles.
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Henrikus SS, Gross MH, Willhoft O, P?hringer T, Lewis JS, McClure AW, Greiwe JF, Palm G, Nans A, Diffley JFX, Costa A. Unwinding of a eukaryotic origin of replication visualized by cryo-EM. Nat Struct Mol Biol. 2024 Aug; 31(8):1265-1276.
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Sreekumar L, Kumari K, Guin K, Bakshi A, Varshney N, Thimmappa BC, Narlikar L, Padinhateeri R, Siddharthan R, Sanyal K. Orc4 spatiotemporally stabilizes centromeric chromatin. Genome Res. 2021 04; 31(4):607-621.
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Sclafani RA, Hesselberth JR. O Cdc7 kinase where art thou? Curr Genet. 2018 Jun; 64(3):677-680.
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Rossbach D, Bryan DS, Hesselberth JR, Sclafani R. Localization of Cdc7 Protein Kinase During DNA Replication in Saccharomyces cerevisiae. G3 (Bethesda). 2017 11 06; 7(11):3757-3774.
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Guan L, He P, Yang F, Zhang Y, Hu Y, Ding J, Hua Y, Zhang Y, Ye Q, Hu J, Wang T, Jin C, Kong D. Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeast Schizosaccharomyces pombe. J Biol Chem. 2017 04 14; 292(15):6056-6075.
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Gaggioli V, Le Viet B, Germe T, Hyrien O. DNA topoisomerase IIa controls replication origin cluster licensing and firing time in Xenopus egg extracts. Nucleic Acids Res. 2013 Aug; 41(15):7313-31.
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Chen X, Liu G, Leffak M. Activation of a human chromosomal replication origin by protein tethering. Nucleic Acids Res. 2013 Jul; 41(13):6460-74.
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Martin MM, Ryan M, Kim R, Zakas AL, Fu H, Lin CM, Reinhold WC, Davis SR, Bilke S, Liu H, Doroshow JH, Reimers MA, Valenzuela MS, Pommier Y, Meltzer PS, Aladjem MI. Genome-wide depletion of replication initiation events in highly transcribed regions. Genome Res. 2011 Nov; 21(11):1822-32.
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Ye J, Su LH, Chen CL, Hu S, Wang J, Yu J, Chiu CH. Analysis of pSC138, the multidrug resistance plasmid of Salmonella enterica serotype Choleraesuis SC-B67. Plasmid. 2011 Mar; 65(2):132-40.
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Liu G, Chen X, Bissler JJ, Sinden RR, Leffak M. Replication-dependent instability at (CTG) x (CAG) repeat hairpins in human cells. Nat Chem Biol. 2010 Sep; 6(9):652-9.
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