 Carnitine
"Carnitine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A constituent of STRIATED MUSCLE and LIVER. It is an amino acid derivative and an essential cofactor for fatty acid metabolism.
| Descriptor ID |
D002331
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| MeSH Number(s) |
D02.092.877.883.099
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Carnitine".
Below are MeSH descriptors whose meaning is more specific than "Carnitine".
This graph shows the total number of publications written about "Carnitine" by people in this website by year, and whether "Carnitine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 2001 | 3 | 0 | 3 | | 2003 | 1 | 0 | 1 | | 2005 | 2 | 0 | 2 | | 2006 | 1 | 0 | 1 | | 2008 | 1 | 1 | 2 | | 2010 | 0 | 2 | 2 | | 2012 | 1 | 1 | 2 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 1 | 4 | 5 | | 2019 | 0 | 1 | 1 | | 2020 | 1 | 2 | 3 | | 2021 | 1 | 2 | 3 | | 2022 | 1 | 2 | 3 | | 2023 | 0 | 1 | 1 | | 2024 | 1 | 2 | 3 | | 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Carnitine" by people in Profiles.
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Solo KJ, Zhang Y, Bharathi SS, Zhang BB, Richert AC, Schmidt AV, Van't Land C, D'Annibale O, Wood TC, Goetzman ES. Oral octanoylcarnitine alleviates exercise intolerance in mouse models of long-chain fatty acid oxidation disorders. JCI Insight. 2025 Nov 24; 10(22).
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D'Annibale O, Phinney W, Crenshaw M, LoPiccolo MK, Elsharkawi I, Shelkowitz E, Pique D, Starosta RT, Larson A, Van Hove JLK, Wood T, Kochhar A. Differentiation of neonatal and infantile onset ECHS1 deficiency using SCEH enzyme activity and plasma acylcarnitine analysis. Mol Genet Metab. 2025 Aug; 145(4):109156.
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Oltman SP, Rogers EE, Baer RJ, Amsalu R, Bandoli G, Chambers CD, Cho H, Dagle JM, Karvonen KL, Kingsmore SF, McKenzie-Sampson S, Momany A, Ontiveros E, Protopsaltis LD, Rand L, Kobayashi ES, Steurer MA, Ryckman KK, Jelliffe-Pawlowski LL. Early Newborn Metabolic Patterning and Sudden Infant Death Syndrome. JAMA Pediatr. 2024 Nov 01; 178(11):1183-1191.
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McKenna CF, Stierwalt HD, Zemski Berry KA, Ehrlicher SE, Robinson MM, Zarini S, Kahn DE, Snell-Bergeon JK, Perreault L, Bergman BC, Newsom SA. Intramuscular diacylglycerol accumulates with acute hyperinsulinemia in insulin-resistant phenotypes. Am J Physiol Endocrinol Metab. 2024 Aug 01; 327(2):E183-E193.
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Nemkov T, Key A, Stephenson D, Earley EJ, Keele GR, Hay A, Amireault P, Casimir M, Dussiot M, Dzieciatkowska M, Reisz JA, Deng X, Stone M, Kleinman S, Spitalnik SL, Hansen KC, Norris PJ, Churchill GA, Busch MP, Roubinian N, Page GP, Zimring JC, Arduini A, D'Alessandro A. Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro. Blood. 2024 06 13; 143(24):2517-2533.
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Phelan DE, Mota C, Strowitzki MJ, Shigemura M, Sznajder JI, Crowe L, Masterson JC, Hayes SE, Reddan B, Yin X, Brennan L, Crean D, Cummins EP. Hypercapnia alters mitochondrial gene expression and acylcarnitine production in monocytes. Immunol Cell Biol. 2023 07; 101(6):556-577.
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Wang D, Ho ES, Cotticelli MG, Xu P, Napierala JS, Hauser LA, Napierala M, Himes BE, Wilson RB, Lynch DR, Mesaros C. Skin fibroblast metabolomic profiling reveals that lipid dysfunction predicts the severity of Friedreich's ataxia. J Lipid Res. 2022 09; 63(9):100255.
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Vaughan OR, Rosario FJ, Chan J, Cox LA, Ferchaud-Roucher V, Zemski-Berry KA, Reusch JEB, Keller AC, Powell TL, Jansson T. Maternal obesity causes fetal cardiac hypertrophy and alters adult offspring myocardial metabolism in mice. J Physiol. 2022 07; 600(13):3169-3191.
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Xu P, Chen C, Zhang Y, Dzieciatkowska M, Brown BC, Zhang W, Xie T, Abdulmalik O, Song A, Tong C, Qi H, Roach R, Kellems RE, D'Alessandro A, Xia Y. Erythrocyte transglutaminase-2 combats hypoxia and chronic kidney disease by promoting oxygen delivery and carnitine homeostasis. Cell Metab. 2022 02 01; 34(2):299-316.e6.
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D'Alessandro A, Thomas T, Akpan IJ, Reisz JA, Cendali FI, Gamboni F, Nemkov T, Thangaraju K, Katneni U, Tanaka K, Kahn S, Wei AZ, Valk JE, Hudson KE, Roh D, Moriconi C, Zimring JC, Hod EA, Spitalnik SL, Buehler PW, Francis RO. Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19. Cells. 2021 09 02; 10(9).
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