 RNA Polymerase II
"RNA Polymerase II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure and transcribes DNA into RNA. It has different requirements for cations and salt than RNA polymerase I and is strongly inhibited by alpha-amanitin. EC 2.7.7.6.
| Descriptor ID |
D012319
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| MeSH Number(s) |
D08.811.913.696.445.735.270.762
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| Concept/Terms |
RNA Polymerase II- RNA Polymerase II
- RNA Polymerase B
- RNA Pol II
- DNA-Dependent RNA Polymerase II
- DNA Dependent RNA Polymerase II
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Below are MeSH descriptors whose meaning is more general than "RNA Polymerase II".
Below are MeSH descriptors whose meaning is more specific than "RNA Polymerase II".
This graph shows the total number of publications written about "RNA Polymerase II" by people in this website by year, and whether "RNA Polymerase II" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 2 | 2 | | 1995 | 2 | 0 | 2 | | 1996 | 2 | 1 | 3 | | 1997 | 1 | 0 | 1 | | 1998 | 3 | 0 | 3 | | 1999 | 2 | 0 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 1 | 2 | | 2002 | 4 | 2 | 6 | | 2003 | 2 | 0 | 2 | | 2004 | 2 | 2 | 4 | | 2005 | 2 | 2 | 4 | | 2006 | 4 | 2 | 6 | | 2007 | 3 | 1 | 4 | | 2008 | 0 | 3 | 3 | | 2009 | 3 | 2 | 5 | | 2010 | 3 | 4 | 7 | | 2011 | 4 | 2 | 6 | | 2012 | 3 | 3 | 6 | | 2013 | 7 | 7 | 14 | | 2014 | 2 | 4 | 6 | | 2015 | 5 | 1 | 6 | | 2016 | 5 | 6 | 11 | | 2017 | 3 | 6 | 9 | | 2018 | 3 | 2 | 5 | | 2019 | 3 | 3 | 6 | | 2020 | 3 | 1 | 4 | | 2021 | 1 | 3 | 4 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA Polymerase II" by people in Profiles.
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Luyties O, Taatjes DJ. The Mediator kinase module: an interface between cell signaling and transcription. Trends Biochem Sci. 2022 04; 47(4):314-327.
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Palacio M, Taatjes DJ. Merging Established Mechanisms with New Insights: Condensates, Hubs, and the Regulation of RNA Polymerase II Transcription. J Mol Biol. 2022 01 15; 434(1):167216.
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Rivas T, Goodrich JA, Kugel JF. The Herpes Simplex Virus 1 Protein ICP4 Acts as both an Activator and a Repressor of Host Genome Transcription during Infection. Mol Cell Biol. 2021 09 24; 41(10):e0017121.
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Saldi T, Riemondy K, Erickson B, Bentley DL. Alternative RNA structures formed during transcription depend on elongation rate and modify RNA processing. Mol Cell. 2021 04 15; 81(8):1789-1801.e5.
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Gally F, Sasse SK, Kurche JS, Gruca MA, Cardwell JH, Okamoto T, Chu HW, Hou X, Poirion OB, Buchanan J, Preissl S, Ren B, Colgan SP, Dowell RD, Yang IV, Schwartz DA, Gerber AN. The MUC5B-associated variant rs35705950 resides within an enhancer subject to lineage- and disease-dependent epigenetic remodeling. JCI Insight. 2021 01 25; 6(2).
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Decker TM. Mechanisms of Transcription Elongation Factor DSIF (Spt4-Spt5). J Mol Biol. 2021 07 09; 433(14):166657.
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Pfleger J, Coleman RC, Ibetti J, Roy R, Kyriazis ID, Gao E, Drosatos K, Koch WJ. Genomic Binding Patterns of Forkhead Box Protein O1 Reveal Its Unique Role in Cardiac Hypertrophy. Circulation. 2020 09; 142(9):882-898.
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Ly E, Powell AE, Goodrich JA, Kugel JF. Release of Human TFIIB from Actively Transcribing Complexes Is Triggered upon Synthesis of 7- and 9-nt RNAs. J Mol Biol. 2020 06 26; 432(14):4049-4060.
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Bacon CW, Challa A, Hyder U, Shukla A, Borkar AN, Bayo J, Liu J, Wu SY, Chiang CM, Kutateladze TG, D'Orso I. KAP1 Is a Chromatin Reader that Couples Steps of RNA Polymerase II Transcription to Sustain Oncogenic Programs. Mol Cell. 2020 06 18; 78(6):1133-1151.e14.
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Schier AC, Taatjes DJ. Structure and mechanism of the RNA polymerase II transcription machinery. Genes Dev. 2020 04 01; 34(7-8):465-488.
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