 RNA Polymerase II
"RNA Polymerase II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure and transcribes DNA into RNA. It has different requirements for cations and salt than RNA polymerase I and is strongly inhibited by alpha-amanitin. EC 2.7.7.6.
| Descriptor ID |
D012319
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| MeSH Number(s) |
D08.811.913.696.445.735.270.762
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| Concept/Terms |
RNA Polymerase II- RNA Polymerase II
- RNA Polymerase B
- RNA Pol II
- DNA-Dependent RNA Polymerase II
- DNA Dependent RNA Polymerase II
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Below are MeSH descriptors whose meaning is more general than "RNA Polymerase II".
Below are MeSH descriptors whose meaning is more specific than "RNA Polymerase II".
This graph shows the total number of publications written about "RNA Polymerase II" by people in this website by year, and whether "RNA Polymerase II" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 1995 | 3 | 1 | 4 | | 1996 | 3 | 1 | 4 | | 1997 | 3 | 0 | 3 | | 1998 | 6 | 0 | 6 | | 1999 | 2 | 0 | 2 | | 2000 | 2 | 0 | 2 | | 2001 | 2 | 1 | 3 | | 2002 | 2 | 1 | 3 | | 2003 | 6 | 0 | 6 | | 2004 | 7 | 2 | 9 | | 2005 | 2 | 4 | 6 | | 2006 | 5 | 3 | 8 | | 2007 | 3 | 1 | 4 | | 2008 | 0 | 4 | 4 | | 2009 | 6 | 3 | 9 | | 2010 | 3 | 7 | 10 | | 2011 | 4 | 4 | 8 | | 2012 | 5 | 2 | 7 | | 2013 | 7 | 7 | 14 | | 2014 | 3 | 5 | 8 | | 2015 | 6 | 0 | 6 | | 2016 | 5 | 6 | 11 | | 2017 | 5 | 9 | 14 | | 2018 | 4 | 4 | 8 | | 2019 | 4 | 3 | 7 | | 2020 | 5 | 1 | 6 | | 2021 | 3 | 3 | 6 | | 2022 | 4 | 4 | 8 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA Polymerase II" by people in Profiles.
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Mattick JS, Amaral PP, Carninci P, Carpenter S, Chang HY, Chen LL, Chen R, Dean C, Dinger ME, Fitzgerald KA, Gingeras TR, Guttman M, Hirose T, Huarte M, Johnson R, Kanduri C, Kapranov P, Lawrence JB, Lee JT, Mendell JT, Mercer TR, Moore KJ, Nakagawa S, Rinn JL, Spector DL, Ulitsky I, Wan Y, Wilusz JE, Wu M. Long non-coding RNAs: definitions, functions, challenges and recommendations. Nat Rev Mol Cell Biol. 2023 06; 24(6):430-447.
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Geisberg JV, Moqtaderi Z, Fong N, Erickson B, Bentley DL, Struhl K. Nucleotide-level linkage of transcriptional elongation and polyadenylation. Elife. 2022 11 24; 11.
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Damon LJ, Aaron J, Palmer AE. Single molecule microscopy to profile the effect of zinc status on transcription factor dynamics. Sci Rep. 2022 Oct 22; 12(1):17789.
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Fong N, Sheridan RM, Ramachandran S, Bentley DL. The pausing zone and control of RNA polymerase II elongation by Spt5: Implications for the pause-release model. Mol Cell. 2022 10 06; 82(19):3632-3645.e4.
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Cortazar MA, Erickson B, Fong N, Pradhan SJ, Ntini E, Bentley DL. Xrn2 substrate mapping identifies torpedo loading sites and extensive premature termination of RNA pol II transcription. Genes Dev. 2022 10 01; 36(19-20):1062-1078.
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Nayak S, Taatjes DJ. SnapShot: Mediator complex structure. Cell. 2022 Sep 01; 185(18):3458-3458.e1.
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Clopper KC, Taatjes DJ. Chemical inhibitors of transcription-associated kinases. Curr Opin Chem Biol. 2022 10; 70:102186.
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Richter WF, Nayak S, Iwasa J, Taatjes DJ. The Mediator complex as a master regulator of transcription by RNA polymerase II. Nat Rev Mol Cell Biol. 2022 11; 23(11):732-749.
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Luyties O, Taatjes DJ. The Mediator kinase module: an interface between cell signaling and transcription. Trends Biochem Sci. 2022 04; 47(4):314-327.
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Palacio M, Taatjes DJ. Merging Established Mechanisms with New Insights: Condensates, Hubs, and the Regulation of RNA Polymerase II Transcription. J Mol Biol. 2022 01 15; 434(1):167216.
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