 RNA Polymerase II
"RNA Polymerase II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure and transcribes DNA into RNA. It has different requirements for cations and salt than RNA polymerase I and is strongly inhibited by alpha-amanitin. EC 2.7.7.6.
| Descriptor ID |
D012319
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| MeSH Number(s) |
D08.811.913.696.445.735.270.762
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| Concept/Terms |
RNA Polymerase II- RNA Polymerase II
- RNA Polymerase B
- RNA Pol II
- DNA-Dependent RNA Polymerase II
- DNA Dependent RNA Polymerase II
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Below are MeSH descriptors whose meaning is more general than "RNA Polymerase II".
Below are MeSH descriptors whose meaning is more specific than "RNA Polymerase II".
This graph shows the total number of publications written about "RNA Polymerase II" by people in this website by year, and whether "RNA Polymerase II" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 2 | 3 | | 1994 | 1 | 0 | 1 | | 1995 | 3 | 1 | 4 | | 1996 | 3 | 1 | 4 | | 1997 | 3 | 0 | 3 | | 1998 | 6 | 0 | 6 | | 1999 | 2 | 0 | 2 | | 2000 | 2 | 0 | 2 | | 2001 | 2 | 1 | 3 | | 2002 | 5 | 2 | 7 | | 2003 | 5 | 0 | 5 | | 2004 | 7 | 2 | 9 | | 2005 | 2 | 3 | 5 | | 2006 | 6 | 4 | 10 | | 2007 | 3 | 1 | 4 | | 2008 | 0 | 4 | 4 | | 2009 | 6 | 3 | 9 | | 2010 | 3 | 7 | 10 | | 2011 | 4 | 4 | 8 | | 2012 | 5 | 3 | 8 | | 2013 | 8 | 8 | 16 | | 2014 | 3 | 5 | 8 | | 2015 | 8 | 1 | 9 | | 2016 | 6 | 6 | 12 | | 2017 | 5 | 9 | 14 | | 2018 | 4 | 3 | 7 | | 2019 | 4 | 2 | 6 | | 2020 | 5 | 0 | 5 |
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Below are the most recent publications written about "RNA Polymerase II" by people in Profiles.
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Liu H, Ramachandran S, Fong N, Phang T, Lee S, Parsa P, Liu X, Harmacek L, Danhorn T, Song T, Oh S, Zhang Q, Chen Z, Zhang Q, Tu TH, Happoldt C, O'Conner B, Janknecht R, Li CY, Marrack P, Kappler J, Leach S, Zhang G. JMJD5 couples with CDK9 to release the paused RNA polymerase II. Proc Natl Acad Sci U S A. 2020 08 18; 117(33):19888-19895.
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Ly E, Powell AE, Goodrich JA, Kugel JF. Release of Human TFIIB from Actively Transcribing Complexes Is Triggered upon Synthesis of 7- and 9-nt RNAs. J Mol Biol. 2020 06 26; 432(14):4049-4060.
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Bacon CW, Challa A, Hyder U, Shukla A, Borkar AN, Bayo J, Liu J, Wu SY, Chiang CM, Kutateladze TG, D'Orso I. KAP1 Is a Chromatin Reader that Couples Steps of RNA Polymerase II Transcription to Sustain Oncogenic Programs. Mol Cell. 2020 06 18; 78(6):1133-1151.e14.
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Schier AC, Taatjes DJ. Structure and mechanism of the RNA polymerase II transcription machinery. Genes Dev. 2020 04 01; 34(7-8):465-488.
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Fant CB, Levandowski CB, Gupta K, Maas ZL, Moir J, Rubin JD, Sawyer A, Esbin MN, Rimel JK, Luyties O, Marr MT, Berger I, Dowell RD, Taatjes DJ. TFIID Enables RNA Polymerase II Promoter-Proximal Pausing. Mol Cell. 2020 05 21; 78(4):785-793.e8.
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Makowski MM, Gaullier G, Luger K. Picking a nucleosome lock: Sequence- and structure-specific recognition of the nucleosome. J Biosci. 2020; 45.
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Cortazar MA, Sheridan RM, Erickson B, Fong N, Glover-Cutter K, Brannan K, Bentley DL. Control of RNA Pol II Speed by PNUTS-PP1 and Spt5 Dephosphorylation Facilitates Termination by a "Sitting Duck Torpedo" Mechanism. Mol Cell. 2019 12 19; 76(6):896-908.e4.
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Steinparzer I, Sedlyarov V, Rubin JD, Eislmayr K, Galbraith MD, Levandowski CB, Vcelkova T, Sneezum L, Wascher F, Amman F, Kleinova R, Bender H, Andrysik Z, Espinosa JM, Superti-Furga G, Dowell RD, Taatjes DJ, Kovarik P. Transcriptional Responses to IFN-? Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions. Mol Cell. 2019 11 07; 76(3):485-499.e8.
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Stratton MS, Bagchi RA, Felisbino MB, Hirsch RA, Smith HE, Riching AS, Enyart BY, Koch KA, Cavasin MA, Alexanian M, Song K, Qi J, Lemieux ME, Srivastava D, Lam MPY, Haldar SM, Lin CY, McKinsey TA. Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation. Circ Res. 2019 09 13; 125(7):662-677.
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El Khattabi L, Zhao H, Kalchschmidt J, Young N, Jung S, Van Blerkom P, Kieffer-Kwon P, Kieffer-Kwon KR, Park S, Wang X, Krebs J, Tripathi S, Sakabe N, Sobreira DR, Huang SC, Rao SSP, Pruett N, Chauss D, Sadler E, Lopez A, Nóbrega MA, Aiden EL, Asturias FJ, Casellas R. A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers. Cell. 2019 08 22; 178(5):1145-1158.e20.
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