 RNA Polymerase II
"RNA Polymerase II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure and transcribes DNA into RNA. It has different requirements for cations and salt than RNA polymerase I and is strongly inhibited by alpha-amanitin. EC 2.7.7.6.
| Descriptor ID |
D012319
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| MeSH Number(s) |
D08.811.913.696.445.735.270.762
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| Concept/Terms |
RNA Polymerase II- RNA Polymerase II
- RNA Polymerase B
- RNA Pol II
- DNA-Dependent RNA Polymerase II
- DNA Dependent RNA Polymerase II
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Below are MeSH descriptors whose meaning is more general than "RNA Polymerase II".
Below are MeSH descriptors whose meaning is more specific than "RNA Polymerase II".
This graph shows the total number of publications written about "RNA Polymerase II" by people in this website by year, and whether "RNA Polymerase II" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 1 | 4 | | 1996 | 3 | 1 | 4 | | 1997 | 3 | 0 | 3 | | 1998 | 6 | 0 | 6 | | 1999 | 2 | 0 | 2 | | 2000 | 2 | 0 | 2 | | 2001 | 2 | 1 | 3 | | 2002 | 5 | 2 | 7 | | 2003 | 6 | 0 | 6 | | 2004 | 7 | 2 | 9 | | 2005 | 2 | 4 | 6 | | 2006 | 5 | 3 | 8 | | 2007 | 3 | 1 | 4 | | 2008 | 0 | 4 | 4 | | 2009 | 6 | 4 | 10 | | 2010 | 3 | 7 | 10 | | 2011 | 4 | 4 | 8 | | 2012 | 5 | 3 | 8 | | 2013 | 7 | 5 | 12 | | 2014 | 3 | 5 | 8 | | 2015 | 6 | 0 | 6 | | 2016 | 5 | 7 | 12 | | 2017 | 5 | 8 | 13 | | 2018 | 4 | 4 | 8 | | 2019 | 4 | 3 | 7 | | 2020 | 5 | 1 | 6 | | 2021 | 4 | 3 | 7 | | 2022 | 4 | 5 | 9 | | 2023 | 0 | 1 | 1 | | 2024 | 7 | 1 | 8 | | 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "RNA Polymerase II" by people in Profiles.
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Nagel M, Taatjes DJ. Regulation of RNA polymerase II transcription through re-initiation and bursting. Mol Cell. 2025 May 15; 85(10):1907-1919.
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Stanley JT, Barone GEF, Townsend HA, Sigauke RF, Allen MA, Dowell RD. LIET model: capturing the kinetics of RNA polymerase from loading to termination. Nucleic Acids Res. 2025 Apr 10; 53(7).
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Blears D, Lou J, Fong N, Mitter R, Sheridan RM, He D, Dirac-Svejstrup AB, Bentley D, Svejstrup JQ. Redundant pathways for removal of defective RNA polymerase II complexes at a promoter-proximal pause checkpoint. Mol Cell. 2024 Dec 19; 84(24):4790-4807.e11.
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Sow A, Lemmond B, Rennick B, Van Wyk J, Martin L, Townsend M, Grupe A, Beaudry R, Healy R, Smith ME, Bonito G. Tuber cumberlandense and T. canirevelatum, two new edible Tuber species from eastern North America discovered by truffle-hunting dogs. Mycologia. 2024 Nov-Dec; 116(6):949-964.
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Palacio M, Taatjes DJ. Transcription regulation through selective partitioning: Weak interactions with a strong foundation. Mol Cell. 2024 Sep 19; 84(18):3375-3377.
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Stallman JK, Johnston PR, Lickey EB, Marlin M, Melie T, Quandt CA, Aime MC, Haelewaters D. Recent fieldwork and fungarium studies double known diversity of Chlorosplenium and improve understanding of species distributions. Mycologia. 2024 Nov-Dec; 116(6):993-1018.
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Bentley DL. Multiple Forms and Functions of Premature Termination by RNA Polymerase II. J Mol Biol. 2025 Jan 01; 437(1):168743.
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Hyder U, Challa A, Thornton M, Nandu T, Kraus WL, D'Orso I. KAP1 negatively regulates RNA polymerase II elongation kinetics to activate signal-induced transcription. Nat Commun. 2024 Jul 12; 15(1):5859.
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Zhao H, Li J, Xiang Y, Malik S, Vartak SV, Veronezi GMB, Young N, Riney M, Kalchschmidt J, Conte A, Jung SK, Ramachandran S, Roeder RG, Shi Y, Casellas R, Asturias FJ. An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II. Mol Cell. 2024 Jul 25; 84(14):2648-2664.e10.
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Walker FM, Sobral LM, Danis E, Sanford B, Donthula S, Balakrishnan I, Wang D, Pierce A, Karam SD, Kargar S, Serkova NJ, Foreman NK, Venkataraman S, Dowell R, Vibhakar R, Dahl NA. Rapid P-TEFb-dependent transcriptional reorganization underpins the glioma adaptive response to radiotherapy. Nat Commun. 2024 May 30; 15(1):4616.
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