RNA Polymerase I
"RNA Polymerase I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. The enzyme functions in the nucleolar structure and transcribes DNA into RNA. It has different requirements for cations and salts than RNA polymerase II and III and is not inhibited by alpha-amanitin.
Descriptor ID |
D012318
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MeSH Number(s) |
D08.811.913.696.445.735.270.750
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Concept/Terms |
RNA Polymerase I- RNA Polymerase I
- Polymerase I, RNA
- DNA-Dependent RNA Polymerase I
- DNA Dependent RNA Polymerase I
- RNA Polymerase A
- Polymerase A, RNA
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Below are MeSH descriptors whose meaning is more general than "RNA Polymerase I".
Below are MeSH descriptors whose meaning is more specific than "RNA Polymerase I".
This graph shows the total number of publications written about "RNA Polymerase I" by people in this website by year, and whether "RNA Polymerase I" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA Polymerase I" by people in Profiles.
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Huffines AK, Engel KL, French SL, Zhang Y, Viktorovskaya OV, Schneider DA. Rate of transcription elongation and sequence-specific pausing by RNA polymerase I directly influence rRNA processing. J Biol Chem. 2022 12; 298(12):102730.
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Clarke AM, Engel KL, Giles KE, Petit CM, Schneider DA. NETSeq reveals heterogeneous nucleotide incorporation by RNA polymerase I. Proc Natl Acad Sci U S A. 2018 12 11; 115(50):E11633-E11641.
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Ucuncuoglu S, Engel KL, Purohit PK, Dunlap DD, Schneider DA, Finzi L. Direct Characterization of Transcription Elongation by RNA Polymerase I. PLoS One. 2016; 11(7):e0159527.
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Engel KL, French SL, Viktorovskaya OV, Beyer AL, Schneider DA. Spt6 Is Essential for rRNA Synthesis by RNA Polymerase I. Mol Cell Biol. 2015 Jul; 35(13):2321-31.
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Viktorovskaya OV, Engel KL, French SL, Cui P, Vandeventer PJ, Pavlovic EM, Beyer AL, Kaplan CD, Schneider DA. Divergent contributions of conserved active site residues to transcription by eukaryotic RNA polymerases I and II. Cell Rep. 2013 Sep 12; 4(5):974-84.
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Lin CH, Platt MD, Ficarro SB, Hoofnagle MH, Shabanowitz J, Comai L, Hunt DF, Owens GK. Mass spectrometric identification of phosphorylation sites of rRNA transcription factor upstream binding factor. Am J Physiol Cell Physiol. 2007 May; 292(5):C1617-24.
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