 Tissue Fixation
"Tissue Fixation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The technique of using FIXATIVES in the preparation of cytologic, histologic, or pathologic specimens for the purpose of maintaining the existing form and structure of all the constituent elements.
| Descriptor ID |
D016707
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| MeSH Number(s) |
E01.370.225.500.620.760.720 E01.370.225.750.600.760.720 E05.200.500.620.760.720 E05.200.750.600.760.720
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tissue Fixation".
Below are MeSH descriptors whose meaning is more specific than "Tissue Fixation".
This graph shows the total number of publications written about "Tissue Fixation" by people in this website by year, and whether "Tissue Fixation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1998 | 2 | 0 | 2 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 2 | 2 | | 2009 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 2 | 2 | | 2015 | 0 | 2 | 2 | | 2017 | 0 | 2 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2024 | 0 | 2 | 2 | | 2025 | 0 | 2 | 2 |
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Below are the most recent publications written about "Tissue Fixation" by people in Profiles.
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Kuhn BK, Vrugt B, Low A, Goodman JE, Attanoos R. Comparative analysis of asbestos body and fiber content in formalin-fixed vs. paraffin-embedded lung tissue. Front Public Health. 2025; 13:1590802.
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Galbraith K, Wu J, Sikkink K, Mohamed H, Reid D, Perez-Arreola M, Belton JM, Nomikou S, Melnyk S, Yang Y, Liechty BL, Jour G, Tsirigos A, Hermel DJ, Beck A, Sigal D, Dahl NA, Vibhakar R, Schmitt A, Snuderl M. Detection of Gene Fusions and Rearrangements in Formalin-Fixed, Paraffin-Embedded Solid Tumor Specimens Using High-Throughput Chromosome Conformation Capture. J Mol Diagn. 2025 May; 27(5):346-359.
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Schwab SK, Harris PS, Michel C, McGinnis CD, Nahomi RB, Assiri MA, Reisdorph R, Henriksen K, Orlicky DJ, Levi M, Rosenberg A, Nagaraj RH, Fritz KS. Quantifying Protein Acetylation in Diabetic Nephropathy from Formalin-Fixed Paraffin-Embedded Tissue. Proteomics Clin Appl. 2024 Nov; 18(6):e202400018.
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Perlman CE, Knudsen L, Smith BJ. The fix is not yet in: recommendation for fixation of lungs within physiological/pathophysiological volume range in preclinical pulmonary structure-function studies. Am J Physiol Lung Cell Mol Physiol. 2024 Aug 01; 327(2):L218-L231.
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May-Zhang AA, Benthal JT, Southard-Smith EM. Hybridization Chain Reaction for mRNA Localization in Single Cells from Mouse and Human Cryosections. Curr Protoc. 2022 May; 2(5):e439.
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Bubak AN, Mescher T, Mariani M, Frietze SE, Hassell JE, Niemeyer CS, Como CN, Burnet AM, Subramanian PS, Cohrs RJ, Mahalingam R, Nagel MA. Targeted RNA Sequencing of Formalin-Fixed, Paraffin-Embedded Temporal Arteries From Giant Cell Arteritis Cases Reveals Viral Signatures. Neurol Neuroimmunol Neuroinflamm. 2021 11; 8(6).
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Pennock ND, Jindal S, Horton W, Sun D, Narasimhan J, Carbone L, Fei SS, Searles R, Harrington CA, Burchard J, Weinmann S, Schedin P, Xia Z. RNA-seq from archival FFPE breast cancer samples: molecular pathway fidelity and novel discovery. BMC Med Genomics. 2019 12 19; 12(1):195.
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Mullegama SV, Alberti MO, Au C, Li Y, Toy T, Tomasian V, Xian RR. Nucleic Acid Extraction from Human Biological Samples. Methods Mol Biol. 2019; 1897:359-383.
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Auerbach SS, Xu M, Merrick BA, Hoenerhoff MJ, Phadke D, Taxman DJ, Shah R, Hong HL, Ton TV, Kovi RC, Sills RC, Pandiri AR. Exome Sequencing of Fresh-frozen or Formalin-fixed Paraffin-embedded B6C3F1/N Mouse Hepatocellular Carcinomas Arising Either Spontaneously or due to Chronic Chemical Exposure. Toxicol Pathol. 2018 08; 46(6):706-718.
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Baena-Del Valle JA, Zheng Q, Hicks JL, Fedor H, Trock BJ, Morrissey C, Corey E, Cornish TC, Sfanos KS, De Marzo AM. Rapid Loss of RNA Detection by In Situ Hybridization in Stored Tissue Blocks and Preservation by Cold Storage of Unstained Slides. Am J Clin Pathol. 2017 Nov 02; 148(5):398-415.
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