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Ischemia alone is sufficient to induce TNF-alpha mRNA and peptide in the myocardium.

Shames BD, Barton HH, Reznikov LL, Cairns CB, Banerjee A, Harken AH, Meng X. Ischemia alone is sufficient to induce TNF-alpha mRNA and peptide in the myocardium. Shock. 2002 Feb; 17(2):114-9.

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