Item Type | Name |
Academic Article
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Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosis.
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Academic Article
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Dietary feeding of silibinin inhibits advance human prostate carcinoma growth in athymic nude mice and increases plasma insulin-like growth factor-binding protein-3 levels.
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Academic Article
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Flavonoid antioxidant silymarin and skin cancer.
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Academic Article
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Mechanisms of energy restriction: effects of corticosterone on cell growth, cell cycle machinery, and apoptosis.
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Academic Article
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Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis.
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Academic Article
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Tumor angiogenesis: a potential target in cancer control by phytochemicals.
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Academic Article
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Inhibition of retinoblastoma protein (Rb) phosphorylation at serine sites and an increase in Rb-E2F complex formation by silibinin in androgen-dependent human prostate carcinoma LNCaP cells: role in prostate cancer prevention.
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Academic Article
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Inhibition of NF-kappaB pathway in grape seed extract-induced apoptotic death of human prostate carcinoma DU145 cells.
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Academic Article
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Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes.
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Academic Article
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Suppression of advanced human prostate tumor growth in athymic mice by silibinin feeding is associated with reduced cell proliferation, increased apoptosis, and inhibition of angiogenesis.
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Academic Article
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Epidermal growth factor receptor mediates silibinin-induced cytotoxicity in a rat glioma cell line.
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Academic Article
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Silibinin sensitizes human prostate carcinoma DU145 cells to cisplatin- and carboplatin-induced growth inhibition and apoptotic death.
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Academic Article
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Synergistic anti-cancer effects of silibinin with conventional cytotoxic agents doxorubicin, cisplatin and carboplatin against human breast carcinoma MCF-7 and MDA-MB468 cells.
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Academic Article
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Silibinin prevents ultraviolet radiation-caused skin damages in SKH-1 hairless mice via a decrease in thymine dimer positive cells and an up-regulation of p53-p21/Cip1 in epidermis.
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Academic Article
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Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages.
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Academic Article
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In vivo suppression of hormone-refractory prostate cancer growth by inositol hexaphosphate: induction of insulin-like growth factor binding protein-3 and inhibition of vascular endothelial growth factor.
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Academic Article
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Inositol hexaphosphate inhibits growth and induces G1 arrest and apoptotic death of androgen-dependent human prostate carcinoma LNCaP cells.
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Academic Article
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Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling.
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Academic Article
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A cancer chemopreventive agent silibinin, targets mitogenic and survival signaling in prostate cancer.
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Academic Article
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Dietary feeding of silibinin prevents early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis.
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Academic Article
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Milk thistle and prostate cancer: differential effects of pure flavonolignans from Silybum marianum on antiproliferative end points in human prostate carcinoma cells.
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Academic Article
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Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.
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Academic Article
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Acacetin inhibits cell growth and cell cycle progression, and induces apoptosis in human prostate cancer cells: structure-activity relationship with linarin and linarin acetate.
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Academic Article
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Silibinin up-regulates DNA-protein kinase-dependent p53 activation to enhance UVB-induced apoptosis in mouse epithelial JB6 cells.
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Academic Article
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Prostate cancer and inositol hexaphosphate: efficacy and mechanisms.
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Academic Article
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Fractionation of grape seed extract and identification of gallic acid as one of the major active constituents causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells.
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Academic Article
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Silibinin efficacy against human hepatocellular carcinoma.
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Academic Article
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Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: evidence for a regulatory loop between p53 and caspase 2.
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Academic Article
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Grape seed extract inhibits in vitro and in vivo growth of human colorectal carcinoma cells.
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Academic Article
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Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells.
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Academic Article
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Mechanisms of action of novel agents for prostate cancer chemoprevention.
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Academic Article
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Silibinin synergizes with mitoxantrone to inhibit cell growth and induce apoptosis in human prostate cancer cells.
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Academic Article
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Fractionation of high molecular weight tannins in grape seed extract and identification of procyanidin B2-3,3'-di-O-gallate as a major active constituent causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells.
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Academic Article
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Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells.
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Academic Article
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Silibinin inhibits inflammatory and angiogenic attributes in photocarcinogenesis in SKH-1 hairless mice.
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Academic Article
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Silibinin inhibits constitutive activation of Stat3, and causes caspase activation and apoptotic death of human prostate carcinoma DU145 cells.
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Academic Article
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Chemopreventive efficacy of silymarin in skin and prostate cancer.
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Academic Article
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p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cells.
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Academic Article
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Gram-scale purification of flavonolignan diastereoisomers from Silybum marianum (Milk Thistle) extract in support of preclinical in vivo studies for prostate cancer chemoprevention.
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Academic Article
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Inducible nitric oxide synthase-vascular endothelial growth factor axis: a potential target to inhibit tumor angiogenesis by dietary agents.
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Academic Article
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Transcription factors: molecular targets for prostate cancer intervention by phytochemicals.
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Academic Article
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Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model.
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Academic Article
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Combinatorial strategies for cancer eradication by silibinin and cytotoxic agents: efficacy and mechanisms.
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Academic Article
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Silibinin impairs constitutively active TGFalpha-EGFR autocrine loop in advanced human prostate carcinoma cells.
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Academic Article
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New combination therapies with cell-cycle agents.
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Academic Article
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Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis.
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Academic Article
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Chemopreventive effects of oral gallic acid feeding on tumor growth and progression in TRAMP mice.
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Academic Article
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Multitargeted therapy of cancer by silymarin.
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Academic Article
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Chemopreventive efficacy of inositol hexaphosphate against prostate tumor growth and progression in TRAMP mice.
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Academic Article
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Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells.
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Academic Article
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Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model.
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Academic Article
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p21/Cip1 and p27/Kip1 Are essential molecular targets of inositol hexaphosphate for its antitumor efficacy against prostate cancer.
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Academic Article
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Silibinin inhibits established prostate tumor growth, progression, invasion, and metastasis and suppresses tumor angiogenesis and epithelial-mesenchymal transition in transgenic adenocarcinoma of the mouse prostate model mice.
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Academic Article
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Gallic acid, an active constituent of grape seed extract, exhibits anti-proliferative, pro-apoptotic and anti-tumorigenic effects against prostate carcinoma xenograft growth in nude mice.
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Academic Article
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Inositol hexaphosphate downregulates both constitutive and ligand-induced mitogenic and cell survival signaling, and causes caspase-mediated apoptotic death of human prostate carcinoma PC-3 cells.
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Academic Article
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Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft.
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Academic Article
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Anticancer and cancer chemopreventive potential of grape seed extract and other grape-based products.
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Academic Article
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Silibinin suppresses spontaneous tumorigenesis in APC min/+ mouse model by modulating beta-catenin pathway.
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Academic Article
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Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators.
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Academic Article
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Inositol hexaphosphate suppresses growth and induces apoptosis in prostate carcinoma cells in culture and nude mouse xenograft: PI3K-Akt pathway as potential target.
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Academic Article
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Chemoprevention of intestinal tumorigenesis in APCmin/+ mice by silibinin.
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Academic Article
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Dietary-feeding of grape seed extract prevents azoxymethane-induced colonic aberrant crypt foci formation in fischer 344 rats.
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Academic Article
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Silibinin exerts sustained growth suppressive effect against human colon carcinoma SW480 xenograft by targeting multiple signaling molecules.
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Academic Article
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Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer.
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Academic Article
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Silibinin prevents lung tumorigenesis in wild-type but not in iNOS-/- mice: potential of real-time micro-CT in lung cancer chemoprevention studies.
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Academic Article
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Grape seed extract upregulates p21 (Cip1) through redox-mediated activation of ERK1/2 and posttranscriptional regulation leading to cell cycle arrest in colon carcinoma HT29 cells.
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Academic Article
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Role of E-cadherin in antimigratory and antiinvasive efficacy of silibinin in prostate cancer cells.
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Academic Article
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Silibinin modulates TNF-a and IFN-? mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells.
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Academic Article
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Silibinin prevents ultraviolet B radiation-induced epidermal damages in JB6 cells and mouse skin in a p53-GADD45a-dependent manner.
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Academic Article
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Generation of reactive oxygen species by grape seed extract causes irreparable DNA damage leading to G2/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells.
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Academic Article
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Angiopreventive efficacy of pure flavonolignans from milk thistle extract against prostate cancer: targeting VEGF-VEGFR signaling.
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Academic Article
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Inositol hexaphosphate inhibits tumor growth, vascularity, and metabolism in TRAMP mice: a multiparametric magnetic resonance study.
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Academic Article
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Anti-cancer efficacy of silybin derivatives -- a structure-activity relationship.
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Academic Article
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Differential effect of grape seed extract against human non-small-cell lung cancer cells: the role of reactive oxygen species and apoptosis induction.
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Academic Article
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Energy deprivation by silibinin in colorectal cancer cells: a double-edged sword targeting both apoptotic and autophagic machineries.
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Academic Article
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Silibinin induces growth inhibition and apoptotic cell death in human lung carcinoma cells.
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Academic Article
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Growth inhibitory and apoptotic effects of inositol hexaphosphate in transgenic adenocarcinoma of mouse prostate (TRAMP-C1) cells.
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Academic Article
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Inositol hexaphosphate inhibits constitutive activation of NF- kappa B in androgen-independent human prostate carcinoma DU145 cells.
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Academic Article
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Grape seed extract inhibits advanced human prostate tumor growth and angiogenesis and upregulates insulin-like growth factor binding protein-3.
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Academic Article
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Synergistic anti-cancer effects of grape seed extract and conventional cytotoxic agent doxorubicin against human breast carcinoma cells.
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Academic Article
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Oral silibinin inhibits lung tumor growth in athymic nude mice and forms a novel chemocombination with doxorubicin targeting nuclear factor kappaB-mediated inducible chemoresistance.
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Academic Article
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A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells.
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Academic Article
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Chemopreventive effects of alpha-santalol on ultraviolet B radiation-induced skin tumor development in SKH-1 hairless mice.
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Academic Article
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Effect of silibinin on the growth and progression of primary lung tumors in mice.
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Academic Article
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Silymarin and epithelial cancer chemoprevention: how close we are to bedside?
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Academic Article
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Silibinin down-regulates survivin protein and mRNA expression and causes caspases activation and apoptosis in human bladder transitional-cell papilloma RT4 cells.
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Academic Article
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Prostate cancer prevention by silibinin.
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Academic Article
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Skin cancer chemopreventive agent, {alpha}-santalol, induces apoptotic death of human epidermoid carcinoma A431 cells via caspase activation together with dissipation of mitochondrial membrane potential and cytochrome c release.
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Academic Article
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Mechanisms and preclinical efficacy of silibinin in preventing skin cancer.
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Academic Article
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Natural flavonoids targeting deregulated cell cycle progression in cancer cells.
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Academic Article
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Prostate cancer chemoprevention by silibinin: bench to bedside.
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Academic Article
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Silibinin inhibits UVB- and epidermal growth factor-induced mitogenic and cell survival signaling involving activator protein-1 and nuclear factor-kappaB in mouse epidermal JB6 cells.
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Academic Article
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Grape seed extract induces anoikis and caspase-mediated apoptosis in human prostate carcinoma LNCaP cells: possible role of ataxia telangiectasia mutated-p53 activation.
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Academic Article
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Differential effect of silibinin on E2F transcription factors and associated biological events in chronically UVB-exposed skin versus tumors in SKH-1 hairless mice.
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Academic Article
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Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells.
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Academic Article
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Downregulation of both p21/Cip1 and p27/Kip1 produces a more aggressive prostate cancer phenotype.
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Academic Article
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A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients.
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Academic Article
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Isosilibinin inhibits advanced human prostate cancer growth in athymic nude mice: comparison with silymarin and silibinin.
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Academic Article
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Grape seed extract induces cell cycle arrest and apoptosis in human colon carcinoma cells.
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Academic Article
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Kava, a tonic for relieving the irrational development of natural preventive agents.
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Academic Article
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Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-kappaB and signal transducers and activators of transcription 3.
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Academic Article
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Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling.
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Academic Article
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Anti-tumor activity of oxypeucedanin from Ostericum koreanum against human prostate carcinoma DU145 cells.
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Academic Article
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Oral grape seed extract inhibits prostate tumor growth and progression in TRAMP mice.
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Academic Article
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Silibinin suppresses in vivo growth of human prostate carcinoma PC-3 tumor xenograft.
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Academic Article
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Large-scale isolation of flavonolignans from Silybum marianum extract affords new minor constituents and preliminary structure-activity relationships.
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Academic Article
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A study of high-dose oral silybin-phytosome followed by prostatectomy in patients with localized prostate cancer.
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Academic Article
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Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice.
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Academic Article
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Oral silibinin inhibits in vivo human bladder tumor xenograft growth involving down-regulation of survivin.
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Academic Article
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Influence of gallate esterification on the activity of procyanidin B2 in androgen-dependent human prostate carcinoma LNCaP cells.
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Academic Article
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Tumor progression stage and anatomical site regulate tumor-associated macrophage and bone marrow-derived monocyte polarization.
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Academic Article
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Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells.
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Academic Article
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Inhibitory effect of silibinin against azoxymethane-induced colon tumorigenesis in A/J mice.
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Academic Article
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Inhibition of azoxymethane-induced colonic aberrant crypt foci formation by silibinin in male Fisher 344 rats.
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Academic Article
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Silibinin feeding alters the metabolic profile in TRAMP prostatic tumors: 1H-NMRS-based metabolomics study.
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Academic Article
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Pachymic acid inhibits cell growth and modulates arachidonic acid metabolism in nonsmall cell lung cancer A549 cells.
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Academic Article
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Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of beta-catenin-dependent signaling.
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Academic Article
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Isosilybin A induces apoptosis in human prostate cancer cells via targeting Akt, NF-?B, and androgen receptor signaling.
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Academic Article
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Effect of silibinin in human colorectal cancer cells: targeting the activation of NF-?B signaling.
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Academic Article
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Interleukin-1beta-induced iNOS expression in human lung carcinoma A549 cells: involvement of STAT and MAPK pathways.
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Academic Article
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Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation.
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Academic Article
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Deletion of p21/Cdkn1a confers protective effect against prostate tumorigenesis in transgenic adenocarcinoma of the mouse prostate model.
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Academic Article
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Chemopreventive and anti-cancer efficacy of silibinin against growth and progression of lung cancer.
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Academic Article
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Rice varietal differences in bioactive bran components for inhibition of colorectal cancer cell growth.
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Academic Article
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Resveratrol selectively induces DNA Damage, independent of Smad4 expression, in its efficacy against human head and neck squamous cell carcinoma.
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Academic Article
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Emerging trends in cancer research: prevention and therapeutics. Preface.
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Academic Article
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Epigenetic modifications and p21-cyclin B1 nexus in anticancer effect of histone deacetylase inhibitors in combination with silibinin on non-small cell lung cancer cells.
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Academic Article
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Chemopreventive properties of dietary rice bran: current status and future prospects.
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Academic Article
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Silibinin synergizes with histone deacetylase and DNA methyltransferase inhibitors in upregulating E-cadherin expression together with inhibition of migration and invasion of human non-small cell lung cancer cells.
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Academic Article
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Molecular mechanisms of silibinin-mediated cancer chemoprevention with major emphasis on prostate cancer.
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Academic Article
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Identifying molecular targets of lifestyle modifications in colon cancer prevention.
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Academic Article
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Promise and potential of silibinin in colorectal cancer management: what patterns can be seen?
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Concept
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Thyroid Neoplasms
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Concept
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Mammary Neoplasms, Experimental
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Concept
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Brain Neoplasms
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Concept
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Lung Neoplasms
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Concept
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Prostatic Neoplasms
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Concept
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Urinary Bladder Neoplasms
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Concept
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Ovarian Neoplasms
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Concept
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Colorectal Neoplasms
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Concept
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Pancreatic Neoplasms
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Concept
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Neoplasms, Radiation-Induced
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Concept
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Kidney Neoplasms
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Concept
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Mouth Neoplasms
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Concept
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Breast Neoplasms
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Concept
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Stomach Neoplasms
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Concept
|
Head and Neck Neoplasms
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Concept
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Neoplasms, Hormone-Dependent
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Concept
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Neoplasms
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Concept
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Skin Neoplasms
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Concept
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Tongue Neoplasms
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Concept
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Colonic Neoplasms
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Concept
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Intestinal Neoplasms
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Concept
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Liver Neoplasms
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Concept
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Uterine Cervical Neoplasms
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Academic Article
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Bitter melon juice activates cellular energy sensor AMP-activated protein kinase causing apoptotic death of human pancreatic carcinoma cells.
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Academic Article
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Targeting tumor microenvironment with silibinin: promise and potential for a translational cancer chemopreventive strategy.
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Academic Article
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Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation.
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Academic Article
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Acacetin inhibits in vitro and in vivo angiogenesis and downregulates Stat signaling and VEGF expression.
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Academic Article
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Poly[3-(3, 4-dihydroxyphenyl) glyceric acid] from Comfrey exerts anti-cancer efficacy against human prostate cancer via targeting androgen receptor, cell cycle arrest and apoptosis.
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Academic Article
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Role of oxidative stress in cytotoxicity of grape seed extract in human bladder cancer cells.
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Academic Article
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Silibinin inhibits prostate cancer cells- and RANKL-induced osteoclastogenesis by targeting NFATc1, NF-?B, and AP-1 activation in RAW264.7 cells.
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Academic Article
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The strategies to control prostate cancer by chemoprevention approaches.
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Academic Article
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SNAI1 is critical for the aggressiveness of prostate cancer cells with low E-cadherin.
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Academic Article
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Procyanidin B2 3,3(?)-di-O-gallate, a biologically active constituent of grape seed extract, induces apoptosis in human prostate cancer cells via targeting NF-?B, Stat3, and AP1 transcription factors.
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Academic Article
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Characterization of azoxymethane-induced colon tumor metastasis to lung in a mouse model relevant to human sporadic colorectal cancer and evaluation of grape seed extract efficacy.
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Academic Article
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Target identification of grape seed extract in colorectal cancer using drug affinity responsive target stability (DARTS) technique: role of endoplasmic reticulum stress response proteins.
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Academic Article
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Silibinin strongly inhibits the growth kinetics of colon cancer stem cell-enriched spheroids by modulating interleukin 4/6-mediated survival signals.
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Academic Article
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Nuclear factor ?B-dependent regulation of angiogenesis, and metastasis in an in vivo model of thyroid cancer is associated with secreted interleukin-8.
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Academic Article
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In vitro and in vivo anticancer efficacy of silibinin against human pancreatic cancer BxPC-3 and PANC-1 cells.
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Academic Article
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Differential effects of grape seed extract against human colorectal cancer cell lines: the intricate role of death receptors and mitochondria.
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Academic Article
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Functional modification of adipocytes by grape seed extract impairs their pro-tumorigenic signaling on colon cancer stem cells and the daughter cancer cells.
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Academic Article
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Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1.
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Academic Article
|
A perspective on chemoprevention by resveratrol in head and neck squamous cell carcinoma.
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Academic Article
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Procyanidin B2 3,3?-di-O-gallate inhibits endothelial cells growth and motility by targeting VEGFR2 and integrin signaling pathways.
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Academic Article
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Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells.
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Academic Article
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Grape seed extract and resveratrol prevent 4-nitroquinoline 1-oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological responses.
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Academic Article
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Silibinin inhibits fibronectin induced motility, invasiveness and survival in human prostate carcinoma PC3 cells via targeting integrin signaling.
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Academic Article
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Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.
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Academic Article
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Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Uptake in Prostate Cancer Mouse Xenografts.
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Academic Article
|
Silibinin prevents prostate cancer cell-mediated differentiation of na?ve fibroblasts into cancer-associated fibroblast phenotype by targeting TGF ?2.
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Academic Article
|
Chemopreventive opportunities to control basal cell carcinoma: Current perspectives.
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Academic Article
|
Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation.
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Academic Article
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Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo.
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Academic Article
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Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells.
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Academic Article
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Silibinin Preferentially Radiosensitizes Prostate Cancer by Inhibiting DNA Repair Signaling.
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Academic Article
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Silibinin and its 2,3-dehydro-derivative inhibit basal cell carcinoma growth via suppression of mitogenic signaling and transcription factors activation.
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Academic Article
|
Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity.
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Academic Article
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Talarolutins A-D: Meroterpenoids from an endophytic fungal isolate of Talaromyces minioluteus.
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Academic Article
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Beneficial effects of the naturally occurring flavonoid silibinin on the prostate cancer microenvironment: role of monocyte chemotactic protein-1 and immune cell recruitment.
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Academic Article
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A novel alkaloid, evodiamine causes nuclear localization of cytochrome-c and induces apoptosis independent of p53 in human lung cancer cells.
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Academic Article
|
Inulanolide A as a new dual inhibitor of NFAT1-MDM2 pathway for breast cancer therapy.
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Academic Article
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Role of p53 in silibinin-mediated inhibition of ultraviolet B radiation-induced DNA damage, inflammation and skin carcinogenesis.
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Academic Article
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Promise of bitter melon (Momordica charantia) bioactives in cancer prevention and therapy.
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Academic Article
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Natural products and colon cancer: current status and future prospects.
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Academic Article
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Anthocyanin-containing purple-fleshed potatoes suppress colon tumorigenesis via elimination of colon cancer stem cells.
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Academic Article
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Silibinin and colorectal cancer chemoprevention: a comprehensive review on mechanisms and efficacy.
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Academic Article
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Fisetin inhibits cellular proliferation and induces mitochondria-dependent apoptosis in human gastric cancer cells.
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Academic Article
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Abrus Agglutinin, a type II ribosome inactivating protein inhibits Akt/PH domain to induce endoplasmic reticulum stress mediated autophagy-dependent cell death.
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Academic Article
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ATG14 facilitated lipophagy in cancer cells induce ER stress mediated mitoptosis through a ROS dependent pathway.
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Academic Article
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An Overview of Ultraviolet B Radiation-Induced Skin Cancer Chemoprevention by Silibinin.
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Academic Article
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Silibinin inhibits hypoxia-induced HIF-1a-mediated signaling, angiogenesis and lipogenesis in prostate cancer cells: In vitro evidence and in vivo functional imaging and metabolomics.
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Academic Article
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Silibinin Treatment Inhibits the Growth of Hedgehog Inhibitor-Resistant Basal Cell Carcinoma Cells via Targeting EGFR-MAPK-Akt and Hedgehog Signaling.
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Academic Article
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Mechanisms and Drug Targets for Pancreatic Cancer Chemoprevention.
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Grant
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CANCER CHEMOPREVENTION BY SILYMARIN
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Grant
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RECEPTOR SIGNALING, PHYTIC ACID AND PROSTATE CANCER
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Grant
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Skin Cancer Chemoprevention by Silibinin: Mechanisms and Efficacy
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Grant
|
CANCER CHEMOPREVENTION BY SILYMARIN
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Grant
|
Prostate Cancer Prevention and Treatment by Silibinin
|
Grant
|
Angioprevention of Lung Tumorigenesis by Silibinin
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Grant
|
Prostate Cancer Chemoprevention by Inositol Hexaphosphate Efficacy and Mechanism
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Grant
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Molecular mechanism of bitter melon juice efficacy against pancreatic cancer.
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Grant
|
Bladder Cancer Prevention by Silibinin
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Grant
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Colon Cancer Chemoprevention by Flavonoid Silibinin
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Academic Article
|
Nintedanib antiangiogenic inhibitor effectiveness in delaying adenocarcinoma progression in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP).
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Academic Article
|
Abrus agglutinin promotes irreparable DNA damage by triggering ROS generation followed by ATM-p73 mediated apoptosis in oral squamous cell carcinoma.
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Academic Article
|
Procyanidin B2 3,3?-di-O-gallate induces oxidative stress-mediated cell death in prostate cancer cells via inhibiting MAP kinase phosphatase activity and activating ERK1/2 and AMPK.
|
Academic Article
|
Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of ?-catenin in colon cancer stem cells.
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Academic Article
|
Exosomal microRNA profiling to identify hypoxia-related biomarkers in prostate cancer.
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Academic Article
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Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells.
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Academic Article
|
Bitter melon juice exerts its efficacy against pancreatic cancer via targeting both bulk and cancer stem cells.
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Academic Article
|
Nintedanib inhibits growth of human prostate carcinoma cells by modulating both cell cycle and angiogenesis regulators.
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Academic Article
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Nutraceuticals in prostate cancer therapeutic strategies and their neo-adjuvant use in diverse populations.
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Academic Article
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A novel approach to target hypoxic cancer cells via combining ?-oxidation inhibitor etomoxir with radiation.
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Academic Article
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Exosome proteomic analyses identify inflammatory phenotype and novel biomarkers in African American prostate cancer patients.
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Academic Article
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Differential effect of grape seed extract and its active constituent procyanidin B2 3,3?-di-O-gallate against prostate cancer stem cells.
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Academic Article
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Silibinin inhibits ultraviolet B radiation-induced mast cells recruitment and bone morphogenetic protein 2 expression in the skin at early stages in Ptch(+/-) mouse model of basal cell carcinoma.
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Concept
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Prostatic Neoplasms, Castration-Resistant
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Academic Article
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Bitter melon juice-intake modulates glucose metabolism and lactate efflux in tumors in its efficacy against pancreatic cancer.
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Academic Article
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Antiangiogenic therapy with Nintedanib affects hypoxia, angiogenesis and apoptosis in the ventral prostate of TRAMP animals.
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Academic Article
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Exosomes secreted by prostate cancer cells under hypoxia promote matrix metalloproteinases activity at pre-metastatic niches.
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Academic Article
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Silibinin and non-melanoma skin cancers.
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Academic Article
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Bitter melon juice intake with gemcitabine intervention circumvents resistance to gemcitabine in pancreatic patient-derived xenograft tumors.
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Academic Article
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Targeting Fat Oxidation in Mouse Prostate Cancer Decreases Tumor Growth and Stimulates Anti-Cancer Immunity.
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Academic Article
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Solid-phase synthesis of curcumin mimics and their anticancer activity against human pancreatic, prostate, and colorectal cancer cell lines.
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Academic Article
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Comparative Pre-clinical Efficacy of Chinese and Indian Cultivars of Bitter Melon (Momordica charantia) against Pancreatic Cancer.
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Academic Article
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Stage-specific differential expression of zinc transporter SLC30A and SLC39A family proteins during prostate tumorigenesis.
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Academic Article
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Chemopreventive efficacy of silibinin against basal cell carcinoma growth and progression in UVB-irradiated Ptch+/- mice.
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Academic Article
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Characterization of stage-specific tumor progression in TMPRSS2-ERG (fusion)-driven and non-fusion-driven prostate cancer in GEM models.
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Academic Article
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Stage-Specific Effect of Inositol Hexaphosphate on Cancer Stem Cell Pool during Growth and Progression of Prostate Tumorigenesis in TRAMP Model.
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Academic Article
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Acacetin induces sustained ERK1/2 activation and RIP1-dependent necroptotic death in breast cancer cells.
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Academic Article
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Integrated Microbiota and Metabolite Changes following Rice Bran Intake during Murine Inflammatory Colitis-Associated Colon Cancer and in Colorectal Cancer Survivors.
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Academic Article
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Differential Effect of Non-Steroidal Anti-Inflammatory Drugs Aspirin and Naproxen against TMPRSS2-ERG (Fusion)-Driven and Non-Fusion-Driven Prostate Cancer.
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Academic Article
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Phytochemicals as Immunomodulatory Molecules in Cancer Therapeutics.
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