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Search Results to John W Kappler

This is a "connection" page, showing the details of why an item matched the keywords from your search.

                     
                     

One or more keywords matched the following items that are connected to Kappler, John

Item TypeName
Academic Article Expression of antigen-specific, major histocompatibility complex-restricted receptors by cortical and medullary thymocytes in situ.
Academic Article Major histocompatibility complex-restricted antigen receptor on T cells. VIII. Role of the LFA-1 molecule.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells.
Academic Article Antigen-specific. I region-restricted interactions in vitro between tumor cell lines and T cell hybridomas.
Academic Article Use of I region-restricted, antigen-specific T cell hybridomas to produce idiotypically specific anti-receptor antibodies.
Academic Article Characterization of the gamma-interferon-mediated induction of antigen-presenting ability in P388D1 cells.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product.
Academic Article Functional and inducible expression of a transfected murine class II major histocompatibility complex gene.
Academic Article Biochemistry and distribution of the T cell receptor.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody.
Academic Article An IL 2-secreting T cell hybridoma that responds to a self class I histocompatibility antigen in the H-2D region.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides.
Academic Article The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas.
Academic Article Functional subsets of B cells defined by quantitative differences in surface I-A.
Academic Article Antigen presentation by Ia+ B cell hybridomas to H-2-restricted T cell hybridomas.
Academic Article Multiple binding sites for bacterial superantigens on soluble class II MHC molecules.
Academic Article Processing and major histocompatibility complex binding of the MTV7 superantigen.
Academic Article The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression.
Academic Article Genetic analysis of low V beta 3 expression in humans.
Academic Article Antigen recognition properties of mutant V beta 3+ T cell receptors are consistent with an immunoglobulin-like structure for the receptor.
Academic Article The bacterial and mouse mammary tumor virus superantigens; two different families of proteins with the same functions.
Academic Article The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma.
Academic Article Coordinate production by a T cell hybridoma of gamma interferon and three other lymphokine activities: multiple activities of a single lymphokine?
Academic Article The responses of mature T cells are not necessarily antagonized by their positively selecting peptide.
Academic Article Interleukin-induced increase in Ia expression by normal mouse B cells.
Academic Article Helper T cells recognise antigen and macrophage surface components simultaneously.
Academic Article T cell positive selection by a high density, low affinity ligand.
Academic Article Selection of antigen-specific T cells by a single IEk peptide combination.
Academic Article CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection.
Academic Article Production of soluble MHC class II proteins with covalently bound single peptides.
Academic Article Positive selection of TcR alpha beta thymocytes: is cortical thymic epithelium an obligatory participant in the presentation of major histocompatibility complex protein?
Academic Article Structures of an MHC class II molecule with covalently bound single peptides.
Academic Article The growth of the very large CD8+ T cell clones in older mice is controlled by cytokines.
Academic Article TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-alpha/beta dimers.
Academic Article T cells down-modulate peptide-MHC complexes on APCs in vivo.
Academic Article Alternate interactions define the binding of peptides to the MHC molecule IA(b).
Academic Article Soluble class I MHC with beta2-microglobulin covalently linked peptides: specific binding to a T cell hybridoma.
Academic Article Mimotopes for alloreactive and conventional T cells in a peptide-MHC display library.
Academic Article TCR-MHC/peptide interactions: kissing-cousins or a shotgun wedding?
Academic Article Analysis of the interaction site for the self superantigen Mls-1a on T cell receptor V beta.
Academic Article Promotion of B cell immune responses via an alum-induced myeloid cell population.
Academic Article Using a baculovirus display library to identify MHC class I mimotopes.
Academic Article Analysis of class II MHC structure in thymic nurse cells.
Academic Article Identification of the staphylococcal enterotoxin A superantigen binding site in the beta 1 domain of the human histocompatibility antigen HLA-DR.
Academic Article The role of the T cell receptor in positive and negative selection of developing T cells.
Academic Article How the T cell repertoire becomes peptide and MHC specific.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. 1983.
Academic Article Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands.
Academic Article HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells.
Academic Article The T cell receptors.
Academic Article Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules.
Academic Article Baculovirus-infected insect cells expressing peptide-MHC complexes elicit protective antitumor immunity.
Academic Article The toxicity of staphylococcal enterotoxin B in mice is mediated by T cells.
Academic Article Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection.
Academic Article Many different Vbeta CDR3s can reveal the inherent MHC reactivity of germline-encoded TCR V regions.
Academic Article The role of H-2-linked genes in helper T-cell function. I. In vitro expression in B cells of immune response genes controlling helper T-cell activity.
Academic Article Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register.
Academic Article T-cell repertoire and thymus.
Academic Article A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers.
Academic Article The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR.
Academic Article Mutations changing the kinetics of class II MHC peptide exchange.
Academic Article Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse.
Academic Article Immunization with an insulin peptide-MHC complex to prevent type 1 diabetes of NOD mice.
Academic Article Influence of the major histocompatibility complex on positive thymic selection of V beta 17a+ T cells.
Academic Article A closer look at TCR germline recognition.
Academic Article The development of helper T cell precursors in mouse thymus.
Academic Article The T-cell repertoire for antigen and MHC.
Academic Article The role of the T-cell receptor in thymocyte maturation: effects in vivo of anti-receptor antibody.
Academic Article Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex.
Academic Article The T cell receptor.
Academic Article Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen.
Academic Article The T cell and its receptor.
Academic Article T cells can distinguish between allogeneic major histocompatibility complex products on different cell types.
Academic Article The effect of thymus environment on T cell development and tolerance.
Academic Article The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens.
Academic Article T cell tolerance by clonal elimination in the thymus.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells. IX. Role of accessory molecules in recognition of antigen plus isolated IA.
Academic Article T cell receptor/MHC interactions in the thymus and the shaping of the T cell repertoire.
Academic Article Components of the ligand for a Ni++ reactive human T cell clone.
Academic Article Characterization of the murine antigenic determinant, designated L3T4a, recognized by monoclonal antibody GK1.5: expression of L3T4a by functional T cell clones appears to correlate primarily with class II MHC antigen-reactivity.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity.
Academic Article The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells: distribution on thymus and peripheral T cells.
Academic Article Antigen recognition by H-2-restricted T cells. II. A tryptic ovalbumin peptide that substitutes for processed antigen.
Academic Article Immunoglobulin-like nature of the alpha-chain of a human T-cell antigen/MHC receptor.
Academic Article Mechanisms of antigen processing and presentation.
Academic Article Antigen-specific, major histocompatibility complex-restricted T cell receptors.
Academic Article Mouse spleen dendritic cells present soluble antigens to antigen-specific T cell hybridomas.
Academic Article Superantigens: mechanism of T-cell stimulation and role in immune responses.
Academic Article Monoclonal antibodies defining functional sites on the toxin superantigen staphylococcal enterotoxin B.
Academic Article Cell surface expression of class II MHC proteins bound by a single peptide.
Academic Article Binding of a soluble alpha beta T-cell receptor to superantigen/major histocompatibility complex ligands.
Academic Article Fibroblasts can induce thymocyte positive selection in vivo.
Academic Article Comparison of peptides bound to spleen and thymus class II.
Academic Article The repertoire of T cells shaped by a single MHC/peptide ligand.
Academic Article Functional analysis of T cells expressing Ia antigens. I. Demonstration of helper T-cell heterogeneity.
Academic Article Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage.
Academic Article Influence of the NH2-terminal amino acid of the T cell receptor alpha chain on major histocompatibility complex (MHC) class II + peptide recognition.
Academic Article T cells can be activated by peptides that are unrelated in sequence to their selecting peptide.
Academic Article Class II major histocompatibility complex-peptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4(+) T cell response to a rheumatoid arthritis-associated antigen.
Academic Article Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes.
Academic Article Crystal structure of mouse H2-M.
Academic Article Invariant chain can bind MHC class II at a site other than the peptide binding groove.
Academic Article An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro.
Academic Article Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.
Academic Article Major histocompatibility complex proteins and TCRs: do they really go together like a horse and carriage?
Academic Article Identification of the region of T cell receptor beta chain that interacts with the self-superantigen MIs-1a.
Academic Article A role for clonal inactivation in T cell tolerance to Mls-1a.
Academic Article Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains.
Academic Article Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide.
Academic Article Superantigens interact with MHC class II molecules outside of the antigen groove.
Academic Article The staphylococcal enterotoxins and their relatives.
Academic Article Evolutionarily conserved amino acids that control TCR-MHC interaction.
Academic Article T cell receptor specificity for major histocompatibility complex proteins.
Academic Article Residues of the variable region of the T-cell-receptor beta-chain that interact with S. aureus toxin superantigens.
Academic Article The T cell receptor: the alpha and beta chains define idiotype, and antigen and MHC specificity.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells: the genetics of expression of an allotype.
Academic Article Effect of prostaglandin E2 on the gamma-interferon induction of antigen-presenting ability in P388D1 cells and on IL-2 production by T-cell hybridomas.
Academic Article The function of antigen-presenting cells in mice with severe combined immunodeficiency.
Academic Article Peptide vaccines prevent tumor growth by activating T cells that respond to native tumor antigens.
Academic Article Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. 1990.
Academic Article Molecular targeting of islet autoantigens.
Academic Article Tolerance to self antigens shapes the T-cell repertoire.
Academic Article Evolutionarily conserved features contribute to a? T cell receptor specificity.
Academic Article T cells and their eons-old obsession with MHC.
Academic Article Compartmentalization of MHC class II gene expression in transgenic mice.
Academic Article The T-cell accessory molecule CD4 recognizes a monomorphic determinant on isolated Ia.
Academic Article Involvement of major histocompatibility complex products in tolerance induction in the thymus.
Academic Article T-cell specificity and repertoire.
Academic Article A T cell receptor V beta segment that imparts reactivity to a class II major histocompatibility complex product.
Academic Article Presentation of antigen, foreign major histocompatibility complex proteins and self by thymus cortical epithelium.
Academic Article Do MHCII-presented neoantigens drive type 1 diabetes and other autoimmune diseases?
Academic Article MAIT cell recognition of MR1 on bacterially infected and uninfected cells.
Academic Article Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells.
Academic Article The antigen-specific, major histocompatibility complex-restricted receptor on T cells.
Academic Article L3T4 interacts with class II molecules on target cells.
Academic Article B cells expressing Ig transgenes respond to a T-dependent antigen only in the presence of Ia-compatible T cells.
Academic Article The T cell repertoire may be biased in favor of MHC recognition.
Concept Major Histocompatibility Complex
Concept Minor Histocompatibility Loci
Concept Minor Histocompatibility Antigens
Concept Histocompatibility Antigens Class I
Concept Histocompatibility Antigens Class II
Concept Histocompatibility Antigens
Concept Histocompatibility
Academic Article Monoclonal antibody blocking the recognition of an insulin peptide-MHC complex modulates type 1 diabetes.
Academic Article Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors.
Academic Article Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion.
Grant REGULATORY MECHANISMS IN THE IMMUNE SYSTEM
Grant Molecular Mechanisms of MHCII Recognition by CD8 T Cells in HIV Non-Progressor Patients
Academic Article The somatically generated portion of T cell receptor CDR3a contributes to the MHC allele specificity of the T cell receptor.
Academic Article C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Academic Article MHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collection.
Academic Article Development of T cell lines sensitive to antigen stimulation.
Concept Histocompatibility Antigen H-2D
Academic Article Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules.
Academic Article Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation.
Academic Article Rational discovery of a cancer neoepitope harboring the KRAS G12D driver mutation.
Academic Article Hidden in Plain View: Discovery of Chimeric Diabetogenic CD4 T Cell Neo-Epitopes.

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