UV photodegradation of murine growth hormone: chemical analysis and immunogenicity consequences.
Fradkin AH, Mozziconacci O, Sch?neich C, Carpenter JF, Randolph TW. UV photodegradation of murine growth hormone: chemical analysis and immunogenicity consequences. Eur J Pharm Biopharm. 2014 Jul; 87(2):395-402.
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Animals
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Antibodies
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Chromatography, Gel
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Chromatography, High Pressure Liquid
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Chromatography, Reverse-Phase
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Cross Reactions
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Dose-Response Relationship, Radiation
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Drug Stability
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Growth Hormone
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Injections, Subcutaneous
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Mice
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Mice, Inbred BALB C
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Mice, Nude
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Photolysis
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Protein Conformation
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Protein Denaturation
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Solubility
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Spectrometry, Mass, Electrospray Ionization
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Spectrophotometry, Infrared
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Tandem Mass Spectrometry
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Technology, Pharmaceutical
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T-Lymphocytes
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Ultraviolet Rays